recent publications
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academic article
- Nogal, B., Bianchi, M., Cottrell, C. A., Kirchdoerfer, R. N., Sewall, L. M., Turner, H. L., Zhao, F., Sok, D., Burton, D. R., Hangartner, L., Ward, A. B. Mapping polyclonal antibody responses in non-human primates vaccinated with HIV env trimer subunit vaccines Cell Reports 2020 30:3755-3765 DOI:10.1016/j.celrep.2020.02.061 PMID:32187547 PMCID:PMC7153566
- Kumar, S., Ju, B., Shapero, B., Lin, X., Ren, L., Zhang, L., Li, D., Zhou, Z. H., Feng, Y., Sou, C., Mann, C. J., Hao, Y. L., et al. A V(H)1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite Science Advances 2020 6 DOI:10.1126/sciadv.abb1328 PMID:32938661 PMCID:PMC7494343
- Rogers, T. F., Zhao, F., Huang, D. L., Beutler, N., Burns, A., He, W. T., Limbo, O., Smith, C., Song, G., Woehl, J., Yang, L. L., Abbott, R. K., et al. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model Science 2020 369:956-963 DOI:10.1126/science.abc7520 PMID:32540903 PMCID:PMC7299280
- Zhao, F., Joyce, C., Burns, A., Nogal, B., Cottrell, C. A., Ramos, A., Biddle, T., Pauthner, M., Nedellec, R., Qureshi, H., Mason, R., Landais, E., et al. Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques Cell Reports 2020 32 DOI:10.1016/j.celrep.2020.108122 PMID:32905766 PMCID:PMC7487785
- Cottrell, C. A., van Schooten, J., Bowman, C. A., Yuan, M., Oyen, D., Shin, M., Morpurgo, R., van der Woude, P., van Breemen, M., Torres, J. L., Patel, R., Gross, J., et al. Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates PLoS Pathogens 2020 16 DOI:10.1371/journal.ppat.1008753 PMID:32866207 PMCID:PMC7485981
- Yuan, M., Liu, H. J., Wu, N. C., Lee, C. C. D., Zhu, X. Y., Zhao, F., Huang, D. L., Yu, W. L., Hua, Y. Z., Tien, H., Rogers, T. F., Landais, E., et al. Structural basis of a shared antibody response to SARS-CoV-2 Science 2020 369:1119-1123 DOI:10.1126/science.abd2321 PMID:32661058 PMCID:PMC7402627
- Steichen, J. M., Lin, Y. C., Havenar-Daughton, C., Pecetta, S., Ozorowski, G., Willis, J. R., Toy, L., Sok, D., Liguori, A., Kratochvil, S., Torres, J. L., Kalyuzhniy, O., et al. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses Science 2019 366 DOI:10.1126/science.aax4380 PMID:31672916
- Melo, M., Porter, E., Zhang, Y., Silva, M., Li, N., Dobosh, B., Liguori, A., Skog, P., Landais, E., Menis, S., Sok, D., Nemazee, D., et al. Immunogenicity of RNA replicons encoding HIV Env immunogens designed for self-assembly into nanoparticles Molecular Therapy 2019 27:2080-2090 DOI:10.1016/j.ymthe.2019.08.007 PMID:31515132 PMCID:PMC6904793
- Umotoy, J., Bagaya, B. S., Joyce, C., Schiffner, T., Menis, S., Saye-Francisco, K. L., Biddle, T., Mohan, S., Vollbrecht, T., Kalyuzhniy, O., Madzorera, S., Kitchin, D., et al. Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan Immunity 2019 51:141-154 DOI:10.1016/j.immuni.2019.06.004 PMID:31315032 PMCID:PMC6642152
- Voss, J. E., Gonzalez-Martin, A., Andrabi, R., Fuller, R. P., Murrell, B., McCoy, L. E., Porter, K., Huang, D., Li, W., Sok, D., Le, K., Briney, B., et al. Reprogramming the antigen specificity of B cells using genome-editing technologies Elife 2019 8 DOI:10.7554/eLife.42995 PMID:30648968 PMCID:PMC6355199
- He, L., Kumar, S., Allen, J. D., Huang, D. L., Lin, X., Mann, C. J., Saye-Francisco, K. L., Copps, J., Sarkar, A., Blizard, G. S., Ozorowski, G., Sok, D., et al. HIV-1 vaccine design through minimizing envelope metastability Science Advances 2018 4 DOI:10.1126/sciadv.aau6769 PMID:30474059 PMCID:PMC6248932
- Sok, D., Burton, D. R. Recent progress in broadly neutralizing antibodies to HIV Nature Immunology 2018 19:1179-1188 DOI:10.1038/s41590-018-0235-7 PMID:30333615
- Cao, L. W., Pauthner, M., Andrabi, R., Rantalainen, K., Berndsen, Z., Diedrich, J. K., Menis, S., Sok, D., Bastidas, R., Park, S. K. R., Delahunty, C. M., He, L., et al. Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer Nature Communications 2018 9 DOI:10.1038/s41467-018-06121-4 PMID:30209313 PMCID:PMC6135743
- Khan, S. N., Sok, D., Tran, K., Movsesyan, A., Dubrovskaya, V., Burton, D. R., Wyatt, R. T. Targeting the HIV-1 spike and coreceptor with bi- and trispecific antibodies for single-component broad inhibition of entry Journal of Virology 2018 92:e00384-18 DOI:10.1128/jvi.00384-18 PMID:29976677
- Magnani, D. M., Rogers, T. F., Beutler, N., Ricciardi, M. J., Bailey, V. K., Gonzalez-Nieto, L., Briney, B., Sok, D., Le, K., Strubel, A., Gutman, M. J., Pedreno-Lopez, N., et al. Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques Science Translational Medicine 2017 9 DOI:10.1126/scitranslmed.aan8184 PMID:28978754
- Voss, J. E., Andrabi, R., McCoy, L. E., de Val, N., Fuller, R. P., Messmer, T., Su, C. Y., Sok, D., Khan, S. N., Garces, F., Pritchard, L. K., Wyatt, R. T., et al. Elicitation of neutralizing antibodies targeting the V2 apex of the HIV Envelope trimer in a wild-type animal model Cell Reports 2017 21:222-235 DOI:10.1016/j.celrep.2017.09.024 PMID:28978475 PMCID:PMC5640805
- Julg, B., Sok, D., Schmidt, S. D., Abbink, P., Newman, R. M., Broge, T., Linde, C., Nkolola, J., Le, K., Su, D., Torabi, J., Pack, M., et al. Protective efficacy of broadly neutralizing antibodies with incomplete neutralization activity against simian-human immunodeficiency virus in rhesus monkeys Journal of Virology 2017 91:e01187-17 DOI:10.1128/jvi.01187-17 PMID:28768869 PMCID:PMC5625479
- Julg, B., Tartaglia, L. J., Keele, B. F., Wagh, K., Pegu, A., Sok, D., Abbink, P., Schmidt, S. D., Wang, K., Chen, X., Joyce, M. G., Georgiev, I. S., et al. Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge Science Translational Medicine 2017 9 DOI:10.1126/scitranslmed.aal1321 PMID:28878010
- He, L., Lin, X., de Val, N., Saye-Francisco, K. L., Mann, C. J., Augst, R., Morris, C. D., Azadnia, P., Zhou, B., Sok, D., Ozorowski, G., Ward, A. B., et al. Hidden lineage complexity of glycan-dependent HIV-1 broadly neutralizing antibodies uncovered by digital panning and native-like gp140 trimer Frontiers in Immunology 2017 8 DOI:10.3389/fimmu.2017.01025
- Sok, D., Le, K. M., Vadnais, M. L., Saye-Francisco, K. L., Jardine, J. G., Torres, J. L., Berndsen, Z. T., Kong, L., Tanfield, R. S., Ruiz, J., Ramos, A., Liang, C. H., et al. Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows Nature 2017 548:108-111 DOI:10.1038/nature23301 PMID:28726771
- Rogers, T. F., Goodwin, E. C., Briney, B., Sok, D., Beutler, N., Strubel, A., Nedellec, R., Le, K., Brown, M. E., Burton, D. R., Walker, L. M. Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors Science Immunology 2017 2 DOI:10.1126/sciimmunol.aan6809 PMID:28821561 PMCID:PMC5892203
- Pauthner, M., Havenar-Daughton, C., Sok, D., Nkolola, J. P., Bastidas, R., Boopathy, A. V., Carnathan, D. G., Chandrashekar, A., Cirelli, K. M., Cottrell, C. A., Eroshkin, A. M., Guenaga, J., et al. Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches Immunity 2017 46:1073-1088 DOI:10.1016/j.immuni.2017.05.007 PMID:28636956 PMCID:PMC5483234
- Xie, J., Sok, D., Wu, N. C., Zheng, T., Zhang, W., Burton, D. R., Lerner, R. A. Immunochemical engineering of cell surfaces to generate virus resistance Proceedings of the National Academy of Sciences of the United States of America 2017 114:4655-4660 DOI:10.1073/pnas.1702764114 PMID:28396429 PMCID:PMC5422804
- Lee, J. H., Andrabi, R., Su, C. Y., Yasmeen, A., Julien, J. P., Kong, L., Wu, N. C., McBride, R., Sok, D., Pauthner, M., Cottrell, C. A., Nieusma, T., et al. A broadly neutralizing antibody targets the dynamic HIV envelope trimer apex via a long, rigidified, and anionic β-hairpin structure Immunity 2017 46:690-702 DOI:10.1016/j.immuni.2017.03.017 PMID:28423342 PMCID:PMC5400778
- Cao, L., Diedrich, J. K., Kulp, D. W., Pauthner, M., He, L., Park, S. K. R., Sok, D., Su, C. Y., Delahunty, C. M., Menis, S., Andrabi, R., Guenaga, J., et al. Global site-specific N-glycosylation analysis of HIV envelope glycoprotein Nature Communications 2017 8 DOI:10.1038/ncomms14954 PMID:28348411
- Irimia, A., Serra, A. M., Sarkar, A., Jacak, R., Kalyuzhniy, O., Sok, D., Saye-Francisco, K. L., Schiffner, T., Tingle, R., Kubitz, M., Adachi, Y., Stanfield, R. L., et al. Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design PLoS Pathogens 2017 13 DOI:10.1371/journal.ppat.1006212 PMID:28225819 PMCID:PMC5338832
- Freund, N. T., Wang, H., Scharf, L., Nogueira, L., Horwitz, J. A., Bar-On, Y., Golijanin, J., Sievers, S. A., Sok, D., Cai, H., Lorenzi, J. C. C., Halper-Stromberg, A., et al. Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller Science Translational Medicine 2017 9 DOI:10.1126/scitranslmed.aal2144 PMID:28100831
- Morris, C. D., Azadnia, P., de Val, N., Vora, N., Honda, A., Giang, E., Saye-Francisco, K., Cheng, Y. S., Lin, X., Mann, C. J., Tang, J., Sok, D., et al. Differential antibody responses to conserved HIV-1 neutralizing epitopes in the context of multivalent scaffolds and native-like gp140 trimers MBio 2017 8:e00036-17 DOI:10.1128/mBio.00036-17 PMID:28246356 PMCID:PMC5347340
- Havenar-Daughton, C., Carnathan, D. G., Torrents de la Peña, A., Pauthner, M., Briney, B., Reiss, S. M., Wood, J. S., Kaushik, K., van Gils, M. J., Rosales, S. L., van der Woude, P., Locci, M., et al. Direct probing of germinal center responses reveals immunological features and bottlenecks for neutralizing antibody responses to HIV Env trimer Cell Reports 2016 17:2195-2209 DOI:10.1016/j.celrep.2016.10.085 PMID:27880897 PMCID:PMC5142765
- Sok, D., Burton, D. R. HIV broadly neutralizing antibodies: taking good care of the 98% Immunity 2016 45:958-960 DOI:10.1016/j.immuni.2016.10.033 PMID:27851923
- Sok, D., Briney, B., Jardine, J. G., Kulp, D. W., Menis, S., Pauthner, M., Wood, A., Lee, E. C., Le, K. M., Jones, M., Ramos, A., Kalyuzhniy, O., et al. Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice Science 2016 353:1557-1560 DOI:10.1126/science.aah3945 PMID:27608668 PMCID:PMC5404394
- Escolano, A., Steichen, J. M., Dosenovic, P., Kulp, D. W., Golijanin, J., Sok, D., Freund, N. T., Gitlin, A. D., Oliveira, T., Araki, T., Lowe, S., Chen, S. T., et al. Sequential immunization elicits broadly neutralizing anti-HIV-1 antibodies in Ig knockin mice Cell 2016 166:1445-1458 DOI:10.1016/j.cell.2016.07.030 PMID:27610569 PMCID:PMC5019122
- Briney, B., Sok, D., Jardine, J. G., Kulp, D. W., Skog, P., Menis, S., Jacak, R., Kalyuzhniy, O., de Val, N., Sesterhenn, F., Le, K. M., Ramos, A., et al. Tailored immunogens direct affinity maturation toward HIV neutralizing antibodies Cell 2016 166:1459-1470 DOI:10.1016/j.cell.2016.08.005 PMID:27610570 PMCID:PMC5018249
- Liu, J., Ghneim, K., Sok, D., Bosche, W. J., Li, Y., Chipriano, E., Berkemeier, B., Oswald, K., Borducchi, E., Cabral, C., Peter, L., Brinkman, A., et al. Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus Science 2016 353:1045-1049 DOI:10.1126/science.aag0491 PMID:27540005
- McCoy, L. E., van Gils, M. J., Ozorowski, G., Messmer, T., Briney, B., Voss, J. E., Kulp, D. W., Macauley, M. S., Sok, D., Pauthner, M., Menis, S., Cottrell, C. A., et al. Holes in the glycan shield of the native HIV Envelope are a target of trimer-elicited neutralizing antibodies Cell Reports 2016 16:2327-2338 DOI:10.1016/j.celrep.2016.07.074 PMID:27545891 PMCID:PMC5007210
- Jardine, J. G., Sok, D., Julien, J. P., Briney, B., Sarkar, A., Liang, C. H., Scherer, E. A., Henry Dunand, C. J., Adachi, Y., Diwanji, D., Hsueh, J., Jones, M., et al. Minimally mutated HIV-1 broadly neutralizing antibodies to guide reductionist vaccine design PLoS Pathogens 2016 12 DOI:10.1371/journal.ppat.1005815 PMID:27560183 PMCID:PMC4999182
- Sok, D., Pauthner, M., Briney, B., Lee, J. H., Saye-Francisco, K. L., Hsueh, J., Ramos, A., Le, K. M., Jones, M., Jardine, J. G., Bastidas, R., Sarkar, A., et al. A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans Immunity 2016 45:31-45 DOI:10.1016/j.immuni.2016.06.026 PMID:27438765 PMCID:PMC4990068
- He, L., de Val, N., Morris, C. D., Vora, N., Thinnes, T. C., Kong, L., Azadnia, P., Sok, D., Zhou, B., Burton, D. R., Wilson, I. A., Nemazee, D., et al. Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles Nature Communications 2016 7 DOI:10.1038/ncomms12041 PMID:27349934 PMCID:PMC4931238
- Kong, L., He, L., de Val, N., Vora, N., Morris, C. D., Azadnia, P., Sok, D., Zhou, B., Burton, D. R., Ward, A. B., Wilson, I. A., Zhu, J. Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability Nature Communications 2016 7 DOI:10.1038/ncomms12040 PMID:27349805 PMCID:PMC4931249
- Jardine, J. G., Kulp, D. W., Havenar-Daughton, C., Sarkar, A., Briney, B., Sok, D., Sesterhenn, F., Ereno-Orbea, J., Kalyuzhniy, O., Deresa, I., Hu, X., Spencer, S., et al. HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogene Science 2016 351:1458-1463 DOI:10.1126/science.aad9195 PMID:27013733 PMCID:PMC4872700
- Bornholdt, Z. A., Turner, H. L., Murin, C. D., Li, W., Sok, D., Souders, C. A., Piper, A. E., Goff, A., Shamblin, J. D., Wollen, S. E., Sprague, T. R., Fusco, M. L., et al. Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak Science 2016 351:1078-1083 DOI:10.1126/science.aad5788 PMID:26912366 PMCID:PMC4900763
- van Gils, M. J., van den Kerkhof, T. L., Ozorowski, G., Cottrell, C. A., Sok, D., Pauthner, M., Pallesen, J., de Val, N., Yasmeen, A., de Taeye, S. W., Schorcht, A., Gumbs, S., et al. An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability Nature Microbiology 2016 2 DOI:10.1038/nmicrobiol.2016.199 PMID:27841852 PMCID:PMC5372380
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Hu, J. K., Crampton, J. C., Cupo, A., Ketas, T., van Gils, M. J., Sliepen, K., de Taeye, S. W., Sok, D., Ozorowski, G., Deresa, I., Stanfield, R., Ward, A. B., et al. Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity Journal of Virology 2015 89:10383-10398 DOI:10.1128/jvi.01653-15 PMID:26246566 PMCID:PMC4580201
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McCoy, L. E., Falkowska, E., Doores, K. J., Le, K., Sok, D., van Gils, M. J., Euler, Z., Burger, J. A., Seaman, M. S., Sanders, R. W., Schuitemaker, H., Poignard, P., et al. Incomplete neutralization and deviation from sigmoidal neutralization curves for HIV broadly neutralizing monoclonal antibodies PLoS Pathogens 2015 11:e1005110 DOI:10.1371/journal.ppat.1005110 PMID:26267277 PMCID:PMC4534392
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Sanders, R. W., van Gils, M. J., Derking, R., Sok, D., Ketas, T. J., Burger, J. A., Ozorowski, G., Cupo, A., Simonich, C., Goo, L., Arendt, H., Kim, H. J., et al. HIV-1 neutralizing antibodies induced by native-like envelope trimers Science 2015 349:aac4223 DOI:10.1126/science.aac4223 PMID:26089353 PMCID:PMC4498988
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Jardine, J. G., Ota, T., Sok, D., Pauthner, M., Kulp, D. W., Kalyuzhniy, O., Skog, P. D., Thinnes, T. C., Bhullar, D., Briney, B., Menis, S., Jones, M., et al. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen Science 2015 349:156-161 DOI:10.1126/science.aac5894 PMID:26089355 PMCID:PMC4669217
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Asmal, M., Luedemann, C., Lavine, C. L., Mach, L. V., Balachandran, H., Brinkley, C., Denny, T. N., Lewis, M. G., Anderson, H., Pal, R., Sok, D., Le, K., et al. Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes Virology 2015 475:37-45 DOI:10.1016/j.virol.2014.10.032 PMID:25462344 PMCID:PMC4280322
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Doores, K. J., Kong, L., Krumm, S. A., Le, K. M., Sok, D., Laserson, U., Garces, F., Poignard, P., Wilson, I. A., Burton, D. R. Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope Journal of Virology 2015 89:1105-1118 DOI:10.1128/jvi02905-14 PMID:25378488 PMCID:PMC4300629
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Sok, D., van Gils, M. J., Pauthner, M., Julien, J. P., Saye-Francisco, K. L., Hsueh, J., Briney, B., Lee, J. H., Le, K. M., Lee, P. S., Hua, Y., Seaman, M. S., et al. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex Proceedings of the National Academy of Sciences of the United States of America 2014 111:17624-17629 DOI:10.1073/pnas.1415789111 PMID:25422458 PMCID:PMC4267403
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He, L., Sok, D., Azadnia, P., Hsueh, J., Landais, E., Simek, M., Koff, W. C., Poignard, P., Burton, D. R., Zhu, J. Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding Scientific Reports 2014 4:6778 DOI:10.1038/srep06778 PMID:25345460 PMCID:PMC4894419
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Garces, F., Sok, D., Kong, L., McBride, R., Kim, H. J., Saye-Francisco, K. F., Julien, J. P., Hua, Y., Cupo, A., Moore, J. P., Paulson, J. C., Ward, A. B., et al. Structural evolution of glycan recognition by a family of potent HIV antibodies Cell 2014 159:69-79 DOI:10.1016/j.cell.2014.09.009 PMID:25259921 PMCID:PMC4278586
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Murin, C. D., Julien, J. P., Sok, D., Stanfield, R. L., Khayat, R., Cupo, A., Moore, J. P., Burton, D. R., Wilson, I. A., Ward, A. B. Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy Journal of Virology 2014 88:10177-10188 DOI:10.1128/jvi.01229-14 PMID:24965454 PMCID:PMC4136306
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Sok, D., Doores, K. J., Briney, B., Le, K. M., Saye-Francisco, K. L., Ramos, A., Kulp, D. W., Julien, J. P., Menis, S., Wickramasinghe, L., Seaman, M. S., Schief, W. R., et al. Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV Science Translational Medicine 2014 6:236ra63 DOI:10.1126/scitranslmed.3008104 PMID:24828077 PMCID:PMC4095976
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Almagro, J. C., Gilliland, G. L., Breden, F., Scott, J. K., Sok, D., Pauthner, M., Reichert, J. M., Helguera, G., Andrabi, R., Mabry, R., Blery, M., Voss, J. E., et al. Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA MAbs 2014 6:577-618 DOI:10.4161/mabs.28421 PMID:24589717 PMCID:PMC4011904
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Julien, J. P., Cupo, A., Sok, D., Stanfield, R. L., Lyumkis, D., Deller, M. C., Klasse, P. J., Burton, D. R., Sanders, R. W., Moore, J. P., Ward, A. B., Wilson, I. A. Crystal structure of a soluble cleaved HIV-1 envelope trimer Science 2013 342:1477-1483 DOI:10.1126/science.1245625 PMID:24179159 PMCID:PMC3886632
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Julien, J. P., Sok, D., Khayat, R., Lee, J. H., Doores, K. J., Walker, L. M., Ramos, A., Diwanji, D. C., Pejchal, R., Cupo, A., Katpally, U., Depetris, R. S., et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans PLoS Pathogens 2013 9:e1003342 DOI:10.1371/journal.ppat.1003342 PMID:23658524 PMCID:PMC3642082
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Sok, D., Laserson, U., Laserson, J., Liu, Y., Vigneault, F., Julien, J. P., Briney, B., Ramos, A., Saye, K. F., Le, K., Mahan, A., Wang, S., et al. The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies PLoS Pathogens 2013 9:e1003754 DOI:10.1371/journal.ppat.1003754 PMID:24278016 PMCID:PMC3836729
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Sok, D., Burton, D. R. SnapShot: broadly neutralizing antibodies Cell 2013 155:728 DOI:10.1016/j.cell.2013.10.009 PMID:24243025 PMCID:PMC4070420
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Jardine, J., Julien, J. P., Menis, S., Ota, T., Kalyuzhniy, O., McGuire, A., Sok, D., Huang, P. S., MacPherson, S., Jones, M., Nieusma, T., Mathison, J., et al. Rational HIV immunogen design to target specific germline B cell receptors Science 2013 340:711-716 DOI:10.1126/science.1234150 PMID:23539181 PMCID:PMC3689846
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Ota, T., Doyle-Cooper, C., Cooper, A. B., Huber, M., Falkowska, E., Doores, K. J., Hangartner, L., Le, K., Sok, D., Jardine, J., Lifson, J., Wu, X. L., et al. Anti-HIV B Cell lines as candidate vaccine biosensors Journal of Immunology 2012 189:4816-4824 DOI:10.4049/jimmunol.1202165 PMID:23066156 PMCID:PMC3626558
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Kazane, S. A., Sok, D., Cho, E. H., Uson, M. L., Kuhn, P., Schultz, P. G., Smider, V. V. Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR Proceedings of the National Academy of Sciences of the United States of America 2012 109:3731-3736 DOI:10.1073/pnas.1120682109 PMID:22345566 PMCID:PMC3309776
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Marrinucci, D., Bethel, K., Kolatkar, A., Luttgen, M. S., Malchiodi, M., Baehring, F., Voigt, K., Lazar, D., Nieva, J., Bazhenova, L., Ko, A. H., Korn, W. M., et al. Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers Physical Biology 2012 9:016003 DOI:10.1088/1478-3975/9/1/016003 PMID:22306768 PMCID:PMC3387996
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Walker, L. M., Sok, D., Nishimura, Y., Donau, O., Sadjadpour, R., Gautam, R., Shingai, M., Pejchal, R., Ramos, A., Simek, M. D., Geng, Y., Wilson, I. A., et al. Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque Proceedings of the National Academy of Sciences of the United States of America 2011 108:20125-20129 DOI:10.1073/pnas.1117531108 PMID:22123961 PMCID:PMC3250170