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Sok, Devin
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Sok, Devin

Graduate Student
Non-Faculty Academic
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  • 2017 - Director, Antibody Discovery and Development, IAVI's Neutralizing Antibody Center , Scripps Research

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    • Nogal, B., Bianchi, M., Cottrell, C. A., Kirchdoerfer, R. N., Sewall, L. M., Turner, H. L., Zhao, F., Sok, D., Burton, D. R., Hangartner, L., Ward, A. B. Mapping polyclonal antibody responses in non-human primates vaccinated with HIV env trimer subunit vaccines Cell Reports  2020 30:3755-3765  DOI:10.1016/j.celrep.2020.02.061  PMID:32187547  PMCID:PMC7153566
    • Kumar, S., Ju, B., Shapero, B., Lin, X., Ren, L., Zhang, L., Li, D., Zhou, Z. H., Feng, Y., Sou, C., Mann, C. J., Hao, Y. L., et al. A V(H)1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite Science Advances  2020 6  DOI:10.1126/sciadv.abb1328  PMID:32938661  PMCID:PMC7494343
    • Rogers, T. F., Zhao, F., Huang, D. L., Beutler, N., Burns, A., He, W. T., Limbo, O., Smith, C., Song, G., Woehl, J., Yang, L. L., Abbott, R. K., et al. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model Science  2020 369:956-963  DOI:10.1126/science.abc7520  PMID:32540903  PMCID:PMC7299280
    • Zhao, F., Joyce, C., Burns, A., Nogal, B., Cottrell, C. A., Ramos, A., Biddle, T., Pauthner, M., Nedellec, R., Qureshi, H., Mason, R., Landais, E., et al. Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques Cell Reports  2020 32  DOI:10.1016/j.celrep.2020.108122  PMID:32905766  PMCID:PMC7487785
    • Cottrell, C. A., van Schooten, J., Bowman, C. A., Yuan, M., Oyen, D., Shin, M., Morpurgo, R., van der Woude, P., van Breemen, M., Torres, J. L., Patel, R., Gross, J., et al. Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates PLoS Pathogens  2020 16  DOI:10.1371/journal.ppat.1008753  PMID:32866207  PMCID:PMC7485981
    • Yuan, M., Liu, H. J., Wu, N. C., Lee, C. C. D., Zhu, X. Y., Zhao, F., Huang, D. L., Yu, W. L., Hua, Y. Z., Tien, H., Rogers, T. F., Landais, E., et al. Structural basis of a shared antibody response to SARS-CoV-2 Science  2020 369:1119-1123  DOI:10.1126/science.abd2321  PMID:32661058  PMCID:PMC7402627
    • Steichen, J. M., Lin, Y. C., Havenar-Daughton, C., Pecetta, S., Ozorowski, G., Willis, J. R., Toy, L., Sok, D., Liguori, A., Kratochvil, S., Torres, J. L., Kalyuzhniy, O., et al. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses Science  2019 366  DOI:10.1126/science.aax4380  PMID:31672916
    • Melo, M., Porter, E., Zhang, Y., Silva, M., Li, N., Dobosh, B., Liguori, A., Skog, P., Landais, E., Menis, S., Sok, D., Nemazee, D., et al. Immunogenicity of RNA replicons encoding HIV Env immunogens designed for self-assembly into nanoparticles Molecular Therapy  2019 27:2080-2090  DOI:10.1016/j.ymthe.2019.08.007  PMID:31515132  PMCID:PMC6904793
    • Umotoy, J., Bagaya, B. S., Joyce, C., Schiffner, T., Menis, S., Saye-Francisco, K. L., Biddle, T., Mohan, S., Vollbrecht, T., Kalyuzhniy, O., Madzorera, S., Kitchin, D., et al. Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan Immunity  2019 51:141-154  DOI:10.1016/j.immuni.2019.06.004  PMID:31315032  PMCID:PMC6642152
    • Voss, J. E., Gonzalez-Martin, A., Andrabi, R., Fuller, R. P., Murrell, B., McCoy, L. E., Porter, K., Huang, D., Li, W., Sok, D., Le, K., Briney, B., et al. Reprogramming the antigen specificity of B cells using genome-editing technologies Elife  2019 8  DOI:10.7554/eLife.42995  PMID:30648968  PMCID:PMC6355199
    • He, L., Kumar, S., Allen, J. D., Huang, D. L., Lin, X., Mann, C. J., Saye-Francisco, K. L., Copps, J., Sarkar, A., Blizard, G. S., Ozorowski, G., Sok, D., et al. HIV-1 vaccine design through minimizing envelope metastability Science Advances  2018 4  DOI:10.1126/sciadv.aau6769  PMID:30474059  PMCID:PMC6248932
    • Sok, D., Burton, D. R. Recent progress in broadly neutralizing antibodies to HIV Nature Immunology  2018 19:1179-1188  DOI:10.1038/s41590-018-0235-7  PMID:30333615
    • Cao, L. W., Pauthner, M., Andrabi, R., Rantalainen, K., Berndsen, Z., Diedrich, J. K., Menis, S., Sok, D., Bastidas, R., Park, S. K. R., Delahunty, C. M., He, L., et al. Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer Nature Communications  2018 9  DOI:10.1038/s41467-018-06121-4  PMID:30209313  PMCID:PMC6135743
    • Khan, S. N., Sok, D., Tran, K., Movsesyan, A., Dubrovskaya, V., Burton, D. R., Wyatt, R. T. Targeting the HIV-1 spike and coreceptor with bi- and trispecific antibodies for single-component broad inhibition of entry Journal of Virology  2018 92:e00384-18  DOI:10.1128/jvi.00384-18  PMID:29976677
    • Magnani, D. M., Rogers, T. F., Beutler, N., Ricciardi, M. J., Bailey, V. K., Gonzalez-Nieto, L., Briney, B., Sok, D., Le, K., Strubel, A., Gutman, M. J., Pedreno-Lopez, N., et al. Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques Science Translational Medicine  2017 9  DOI:10.1126/scitranslmed.aan8184  PMID:28978754
    • Voss, J. E., Andrabi, R., McCoy, L. E., de Val, N., Fuller, R. P., Messmer, T., Su, C. Y., Sok, D., Khan, S. N., Garces, F., Pritchard, L. K., Wyatt, R. T., et al. Elicitation of neutralizing antibodies targeting the V2 apex of the HIV Envelope trimer in a wild-type animal model Cell Reports  2017 21:222-235  DOI:10.1016/j.celrep.2017.09.024  PMID:28978475  PMCID:PMC5640805
    • Julg, B., Sok, D., Schmidt, S. D., Abbink, P., Newman, R. M., Broge, T., Linde, C., Nkolola, J., Le, K., Su, D., Torabi, J., Pack, M., et al. Protective efficacy of broadly neutralizing antibodies with incomplete neutralization activity against simian-human immunodeficiency virus in rhesus monkeys Journal of Virology  2017 91:e01187-17  DOI:10.1128/jvi.01187-17  PMID:28768869  PMCID:PMC5625479
    • Julg, B., Tartaglia, L. J., Keele, B. F., Wagh, K., Pegu, A., Sok, D., Abbink, P., Schmidt, S. D., Wang, K., Chen, X., Joyce, M. G., Georgiev, I. S., et al. Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge Science Translational Medicine  2017 9  DOI:10.1126/scitranslmed.aal1321  PMID:28878010
    • He, L., Lin, X., de Val, N., Saye-Francisco, K. L., Mann, C. J., Augst, R., Morris, C. D., Azadnia, P., Zhou, B., Sok, D., Ozorowski, G., Ward, A. B., et al. Hidden lineage complexity of glycan-dependent HIV-1 broadly neutralizing antibodies uncovered by digital panning and native-like gp140 trimer Frontiers in Immunology  2017 8  DOI:10.3389/fimmu.2017.01025
    • Sok, D., Le, K. M., Vadnais, M. L., Saye-Francisco, K. L., Jardine, J. G., Torres, J. L., Berndsen, Z. T., Kong, L., Tanfield, R. S., Ruiz, J., Ramos, A., Liang, C. H., et al. Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows Nature  2017 548:108-111  DOI:10.1038/nature23301  PMID:28726771
    • Rogers, T. F., Goodwin, E. C., Briney, B., Sok, D., Beutler, N., Strubel, A., Nedellec, R., Le, K., Brown, M. E., Burton, D. R., Walker, L. M. Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors Science Immunology  2017 2  DOI:10.1126/sciimmunol.aan6809  PMID:28821561  PMCID:PMC5892203
    • Pauthner, M., Havenar-Daughton, C., Sok, D., Nkolola, J. P., Bastidas, R., Boopathy, A. V., Carnathan, D. G., Chandrashekar, A., Cirelli, K. M., Cottrell, C. A., Eroshkin, A. M., Guenaga, J., et al. Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches Immunity  2017 46:1073-1088  DOI:10.1016/j.immuni.2017.05.007  PMID:28636956  PMCID:PMC5483234
    • Xie, J., Sok, D., Wu, N. C., Zheng, T., Zhang, W., Burton, D. R., Lerner, R. A. Immunochemical engineering of cell surfaces to generate virus resistance Proceedings of the National Academy of Sciences of the United States of America  2017 114:4655-4660  DOI:10.1073/pnas.1702764114  PMID:28396429  PMCID:PMC5422804
    • Lee, J. H., Andrabi, R., Su, C. Y., Yasmeen, A., Julien, J. P., Kong, L., Wu, N. C., McBride, R., Sok, D., Pauthner, M., Cottrell, C. A., Nieusma, T., et al. A broadly neutralizing antibody targets the dynamic HIV envelope trimer apex via a long, rigidified, and anionic β-hairpin structure Immunity  2017 46:690-702  DOI:10.1016/j.immuni.2017.03.017  PMID:28423342  PMCID:PMC5400778
    • Cao, L., Diedrich, J. K., Kulp, D. W., Pauthner, M., He, L., Park, S. K. R., Sok, D., Su, C. Y., Delahunty, C. M., Menis, S., Andrabi, R., Guenaga, J., et al. Global site-specific N-glycosylation analysis of HIV envelope glycoprotein Nature Communications  2017 8  DOI:10.1038/ncomms14954  PMID:28348411
    • Irimia, A., Serra, A. M., Sarkar, A., Jacak, R., Kalyuzhniy, O., Sok, D., Saye-Francisco, K. L., Schiffner, T., Tingle, R., Kubitz, M., Adachi, Y., Stanfield, R. L., et al. Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design PLoS Pathogens  2017 13  DOI:10.1371/journal.ppat.1006212  PMID:28225819  PMCID:PMC5338832
    • Freund, N. T., Wang, H., Scharf, L., Nogueira, L., Horwitz, J. A., Bar-On, Y., Golijanin, J., Sievers, S. A., Sok, D., Cai, H., Lorenzi, J. C. C., Halper-Stromberg, A., et al. Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller Science Translational Medicine  2017 9  DOI:10.1126/scitranslmed.aal2144  PMID:28100831
    • Morris, C. D., Azadnia, P., de Val, N., Vora, N., Honda, A., Giang, E., Saye-Francisco, K., Cheng, Y. S., Lin, X., Mann, C. J., Tang, J., Sok, D., et al. Differential antibody responses to conserved HIV-1 neutralizing epitopes in the context of multivalent scaffolds and native-like gp140 trimers MBio  2017 8:e00036-17  DOI:10.1128/mBio.00036-17  PMID:28246356  PMCID:PMC5347340
    • Havenar-Daughton, C., Carnathan, D. G., Torrents de la Peña, A., Pauthner, M., Briney, B., Reiss, S. M., Wood, J. S., Kaushik, K., van Gils, M. J., Rosales, S. L., van der Woude, P., Locci, M., et al. Direct probing of germinal center responses reveals immunological features and bottlenecks for neutralizing antibody responses to HIV Env trimer Cell Reports  2016 17:2195-2209  DOI:10.1016/j.celrep.2016.10.085  PMID:27880897  PMCID:PMC5142765
    • Sok, D., Burton, D. R. HIV broadly neutralizing antibodies: taking good care of the 98% Immunity  2016 45:958-960  DOI:10.1016/j.immuni.2016.10.033  PMID:27851923
    • Sok, D., Briney, B., Jardine, J. G., Kulp, D. W., Menis, S., Pauthner, M., Wood, A., Lee, E. C., Le, K. M., Jones, M., Ramos, A., Kalyuzhniy, O., et al. Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice Science  2016 353:1557-1560  DOI:10.1126/science.aah3945  PMID:27608668  PMCID:PMC5404394
    • Escolano, A., Steichen, J. M., Dosenovic, P., Kulp, D. W., Golijanin, J., Sok, D., Freund, N. T., Gitlin, A. D., Oliveira, T., Araki, T., Lowe, S., Chen, S. T., et al. Sequential immunization elicits broadly neutralizing anti-HIV-1 antibodies in Ig knockin mice Cell  2016 166:1445-1458  DOI:10.1016/j.cell.2016.07.030  PMID:27610569  PMCID:PMC5019122
    • Briney, B., Sok, D., Jardine, J. G., Kulp, D. W., Skog, P., Menis, S., Jacak, R., Kalyuzhniy, O., de Val, N., Sesterhenn, F., Le, K. M., Ramos, A., et al. Tailored immunogens direct affinity maturation toward HIV neutralizing antibodies Cell  2016 166:1459-1470  DOI:10.1016/j.cell.2016.08.005  PMID:27610570  PMCID:PMC5018249
    • Liu, J., Ghneim, K., Sok, D., Bosche, W. J., Li, Y., Chipriano, E., Berkemeier, B., Oswald, K., Borducchi, E., Cabral, C., Peter, L., Brinkman, A., et al. Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus Science  2016 353:1045-1049  DOI:10.1126/science.aag0491  PMID:27540005
    • McCoy, L. E., van Gils, M. J., Ozorowski, G., Messmer, T., Briney, B., Voss, J. E., Kulp, D. W., Macauley, M. S., Sok, D., Pauthner, M., Menis, S., Cottrell, C. A., et al. Holes in the glycan shield of the native HIV Envelope are a target of trimer-elicited neutralizing antibodies Cell Reports  2016 16:2327-2338  DOI:10.1016/j.celrep.2016.07.074  PMID:27545891  PMCID:PMC5007210
    • Jardine, J. G., Sok, D., Julien, J. P., Briney, B., Sarkar, A., Liang, C. H., Scherer, E. A., Henry Dunand, C. J., Adachi, Y., Diwanji, D., Hsueh, J., Jones, M., et al. Minimally mutated HIV-1 broadly neutralizing antibodies to guide reductionist vaccine design PLoS Pathogens  2016 12  DOI:10.1371/journal.ppat.1005815  PMID:27560183  PMCID:PMC4999182
    • Sok, D., Pauthner, M., Briney, B., Lee, J. H., Saye-Francisco, K. L., Hsueh, J., Ramos, A., Le, K. M., Jones, M., Jardine, J. G., Bastidas, R., Sarkar, A., et al. A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans Immunity  2016 45:31-45  DOI:10.1016/j.immuni.2016.06.026  PMID:27438765  PMCID:PMC4990068
    • He, L., de Val, N., Morris, C. D., Vora, N., Thinnes, T. C., Kong, L., Azadnia, P., Sok, D., Zhou, B., Burton, D. R., Wilson, I. A., Nemazee, D., et al. Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles Nature Communications  2016 7  DOI:10.1038/ncomms12041  PMID:27349934  PMCID:PMC4931238
    • Kong, L., He, L., de Val, N., Vora, N., Morris, C. D., Azadnia, P., Sok, D., Zhou, B., Burton, D. R., Ward, A. B., Wilson, I. A., Zhu, J. Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability Nature Communications  2016 7  DOI:10.1038/ncomms12040  PMID:27349805  PMCID:PMC4931249
    • Jardine, J. G., Kulp, D. W., Havenar-Daughton, C., Sarkar, A., Briney, B., Sok, D., Sesterhenn, F., Ereno-Orbea, J., Kalyuzhniy, O., Deresa, I., Hu, X., Spencer, S., et al. HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogene Science  2016 351:1458-1463  DOI:10.1126/science.aad9195  PMID:27013733  PMCID:PMC4872700
    • Bornholdt, Z. A., Turner, H. L., Murin, C. D., Li, W., Sok, D., Souders, C. A., Piper, A. E., Goff, A., Shamblin, J. D., Wollen, S. E., Sprague, T. R., Fusco, M. L., et al. Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak Science  2016 351:1078-1083  DOI:10.1126/science.aad5788  PMID:26912366  PMCID:PMC4900763
    • van Gils, M. J., van den Kerkhof, T. L., Ozorowski, G., Cottrell, C. A., Sok, D., Pauthner, M., Pallesen, J., de Val, N., Yasmeen, A., de Taeye, S. W., Schorcht, A., Gumbs, S., et al. An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability Nature Microbiology  2016 2  DOI:10.1038/nmicrobiol.2016.199  PMID:27841852  PMCID:PMC5372380
    • degree-related publication Hu, J. K., Crampton, J. C., Cupo, A., Ketas, T., van Gils, M. J., Sliepen, K., de Taeye, S. W., Sok, D., Ozorowski, G., Deresa, I., Stanfield, R., Ward, A. B., et al. Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity Journal of Virology  2015 89:10383-10398  DOI:10.1128/jvi.01653-15  PMID:26246566  PMCID:PMC4580201
    • degree-related publication McCoy, L. E., Falkowska, E., Doores, K. J., Le, K., Sok, D., van Gils, M. J., Euler, Z., Burger, J. A., Seaman, M. S., Sanders, R. W., Schuitemaker, H., Poignard, P., et al. Incomplete neutralization and deviation from sigmoidal neutralization curves for HIV broadly neutralizing monoclonal antibodies PLoS Pathogens  2015 11:e1005110  DOI:10.1371/journal.ppat.1005110  PMID:26267277  PMCID:PMC4534392
    • degree-related publication Sanders, R. W., van Gils, M. J., Derking, R., Sok, D., Ketas, T. J., Burger, J. A., Ozorowski, G., Cupo, A., Simonich, C., Goo, L., Arendt, H., Kim, H. J., et al. HIV-1 neutralizing antibodies induced by native-like envelope trimers Science  2015 349:aac4223  DOI:10.1126/science.aac4223  PMID:26089353  PMCID:PMC4498988
    • degree-related publication Jardine, J. G., Ota, T., Sok, D., Pauthner, M., Kulp, D. W., Kalyuzhniy, O., Skog, P. D., Thinnes, T. C., Bhullar, D., Briney, B., Menis, S., Jones, M., et al. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen Science  2015 349:156-161  DOI:10.1126/science.aac5894  PMID:26089355  PMCID:PMC4669217
    • degree-related publication Asmal, M., Luedemann, C., Lavine, C. L., Mach, L. V., Balachandran, H., Brinkley, C., Denny, T. N., Lewis, M. G., Anderson, H., Pal, R., Sok, D., Le, K., et al. Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes Virology  2015 475:37-45  DOI:10.1016/j.virol.2014.10.032  PMID:25462344  PMCID:PMC4280322
    • degree-related publication Doores, K. J., Kong, L., Krumm, S. A., Le, K. M., Sok, D., Laserson, U., Garces, F., Poignard, P., Wilson, I. A., Burton, D. R. Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope Journal of Virology  2015 89:1105-1118  DOI:10.1128/jvi02905-14  PMID:25378488  PMCID:PMC4300629
    • degree-related publication Sok, D., van Gils, M. J., Pauthner, M., Julien, J. P., Saye-Francisco, K. L., Hsueh, J., Briney, B., Lee, J. H., Le, K. M., Lee, P. S., Hua, Y., Seaman, M. S., et al. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex Proceedings of the National Academy of Sciences of the United States of America  2014 111:17624-17629  DOI:10.1073/pnas.1415789111  PMID:25422458  PMCID:PMC4267403
    • degree-related publication He, L., Sok, D., Azadnia, P., Hsueh, J., Landais, E., Simek, M., Koff, W. C., Poignard, P., Burton, D. R., Zhu, J. Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding Scientific Reports  2014 4:6778  DOI:10.1038/srep06778  PMID:25345460  PMCID:PMC4894419
    • degree-related publication Garces, F., Sok, D., Kong, L., McBride, R., Kim, H. J., Saye-Francisco, K. F., Julien, J. P., Hua, Y., Cupo, A., Moore, J. P., Paulson, J. C., Ward, A. B., et al. Structural evolution of glycan recognition by a family of potent HIV antibodies Cell  2014 159:69-79  DOI:10.1016/j.cell.2014.09.009  PMID:25259921  PMCID:PMC4278586
    • degree-related publication Murin, C. D., Julien, J. P., Sok, D., Stanfield, R. L., Khayat, R., Cupo, A., Moore, J. P., Burton, D. R., Wilson, I. A., Ward, A. B. Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy Journal of Virology  2014 88:10177-10188  DOI:10.1128/jvi.01229-14  PMID:24965454  PMCID:PMC4136306
    • degree-related publication Sok, D., Doores, K. J., Briney, B., Le, K. M., Saye-Francisco, K. L., Ramos, A., Kulp, D. W., Julien, J. P., Menis, S., Wickramasinghe, L., Seaman, M. S., Schief, W. R., et al. Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV Science Translational Medicine  2014 6:236ra63  DOI:10.1126/scitranslmed.3008104  PMID:24828077  PMCID:PMC4095976
    • degree-related publication Almagro, J. C., Gilliland, G. L., Breden, F., Scott, J. K., Sok, D., Pauthner, M., Reichert, J. M., Helguera, G., Andrabi, R., Mabry, R., Blery, M., Voss, J. E., et al. Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA MAbs  2014 6:577-618  DOI:10.4161/mabs.28421  PMID:24589717  PMCID:PMC4011904
    • degree-related publication Julien, J. P., Cupo, A., Sok, D., Stanfield, R. L., Lyumkis, D., Deller, M. C., Klasse, P. J., Burton, D. R., Sanders, R. W., Moore, J. P., Ward, A. B., Wilson, I. A. Crystal structure of a soluble cleaved HIV-1 envelope trimer Science  2013 342:1477-1483  DOI:10.1126/science.1245625  PMID:24179159  PMCID:PMC3886632
    • degree-related publication Julien, J. P., Sok, D., Khayat, R., Lee, J. H., Doores, K. J., Walker, L. M., Ramos, A., Diwanji, D. C., Pejchal, R., Cupo, A., Katpally, U., Depetris, R. S., et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans PLoS Pathogens  2013 9:e1003342  DOI:10.1371/journal.ppat.1003342  PMID:23658524  PMCID:PMC3642082
    • degree-related publication Sok, D., Laserson, U., Laserson, J., Liu, Y., Vigneault, F., Julien, J. P., Briney, B., Ramos, A., Saye, K. F., Le, K., Mahan, A., Wang, S., et al. The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies PLoS Pathogens  2013 9:e1003754  DOI:10.1371/journal.ppat.1003754  PMID:24278016  PMCID:PMC3836729
    • degree-related publication Sok, D., Burton, D. R. SnapShot: broadly neutralizing antibodies Cell  2013 155:728  DOI:10.1016/j.cell.2013.10.009  PMID:24243025  PMCID:PMC4070420
    • degree-related publication Jardine, J., Julien, J. P., Menis, S., Ota, T., Kalyuzhniy, O., McGuire, A., Sok, D., Huang, P. S., MacPherson, S., Jones, M., Nieusma, T., Mathison, J., et al. Rational HIV immunogen design to target specific germline B cell receptors Science  2013 340:711-716  DOI:10.1126/science.1234150  PMID:23539181  PMCID:PMC3689846
    • degree-related publication Ota, T., Doyle-Cooper, C., Cooper, A. B., Huber, M., Falkowska, E., Doores, K. J., Hangartner, L., Le, K., Sok, D., Jardine, J., Lifson, J., Wu, X. L., et al. Anti-HIV B Cell lines as candidate vaccine biosensors Journal of Immunology  2012 189:4816-4824  DOI:10.4049/jimmunol.1202165  PMID:23066156  PMCID:PMC3626558
    • degree-related publication Kazane, S. A., Sok, D., Cho, E. H., Uson, M. L., Kuhn, P., Schultz, P. G., Smider, V. V. Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR Proceedings of the National Academy of Sciences of the United States of America  2012 109:3731-3736  DOI:10.1073/pnas.1120682109  PMID:22345566  PMCID:PMC3309776
    • degree-related publication Marrinucci, D., Bethel, K., Kolatkar, A., Luttgen, M. S., Malchiodi, M., Baehring, F., Voigt, K., Lazar, D., Nieva, J., Bazhenova, L., Ko, A. H., Korn, W. M., et al. Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers Physical Biology  2012 9:016003  DOI:10.1088/1478-3975/9/1/016003  PMID:22306768  PMCID:PMC3387996
    • degree-related publication Walker, L. M., Sok, D., Nishimura, Y., Donau, O., Sadjadpour, R., Gautam, R., Shingai, M., Pejchal, R., Ramos, A., Simek, M. D., Geng, Y., Wilson, I. A., et al. Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque Proceedings of the National Academy of Sciences of the United States of America  2011 108:20125-20129  DOI:10.1073/pnas.1117531108  PMID:22123961  PMCID:PMC3250170
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Background

education and training

  • Ph.D. in Chemistry, Scripps Research 2008 - 2014
  • B.S. in Chemistry, Stanford University 2004 - 2008

advisee of

  • graduate advising relationship

    • Kuhn, Peter, Ph.D.  candidacy, 2009 - 2014
    • Burton, Dennis, Ph.D.  candidacy, 2009 - 2014
    • Stevens, Raymond, Ph.D.  candidacy, 2009 - 2014
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Contact

full name

  • Devin Sok

geographic location

  • Scripps California 

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