academic article

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• Greving, M. P., Patti, G. J., Siuzdak, G. Nanostructure-initiator mass spectrometry metabolite analysis and imaging Analytical Chemistry  2011 83:2-7  DOI:10.1021/ac101565f  PMID:21049956  PMCID:PMC3012143
• Pendyala, G., Trauger, S. A., Siuzdak, G., Fox, H. S. Short communication: Quantitative proteomic plasma profiling reveals activation of host defense to oxidative stress in chronic SIV and methamphetamine comorbidity AIDS Research and Human Retroviruses  2011 27:179-182  DOI:10.1089/aid.2010.0090  PMID:20929344  PMCID:PMC3045074
• Powers, M. E., Smith, P. A., Roberts, T. C., Fowler, B. J., King, C. C., Trauger, S. A., Siuzdak, G., Romesberg, F. E. Type I signal peptidase and protein secretion in Staphylococcus epidermidis Journal of Bacteriology  2011 193:340-348  DOI:10.1128/jb.01052-10  PMID:21075926  PMCID:PMC3019839
• Tautenhahn, R., Patti, G. J., Kalisiak, E., Miyamoto, T., Schmidt, M., Lo, F. Y., McBee, J., Baliga, N. S., Siuzdak, G. metaXCMS: second-order analysis of untargeted metabolomics data Analytical Chemistry  2011 83:696-700  DOI:10.1021/ac102980g  PMID:21174458  PMCID:PMC3654666
• Lowe, R. D., Szili, E. J., Kirkbride, P., Thissen, H., Siuzdak, G., Voelcker, N. H. Combined immunocapture and laser desorption/ionization mass spectrometry on porous silicon Analytical Chemistry  2010 82:4201-4208  DOI:10.1021/ac100455x  PMID:20411919
• Patti, G. J., Woo, H. K., Yanes, O., Shriver, L., Thomas, D., Uritboonthai, W., Apon, J. V., Steenwyk, R., Manchester, M., Siuzdak, G. Detection of carbohydrates and steroids by cation-enhanced nanostructure-initiator mass spectrometry (NIMS) for biofluid analysis and tissue imaging Analytical Chemistry  2010 82:121-128  DOI:10.1021/ac9014353  PMID:19961200  PMCID:PMC2802282
• Facciotti, M. T., Pang, W. L., Lo, F. Y., Whitehead, K., Koide, T., Masumura, K., Pan, M., Kaur, A., Larsen, D. J., Reiss, D. J., Hoang, L., Kalisiak, E., et al. Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis BMC Systems Biology  2010 4:64  DOI:10.1186/1752-0509-4-64  PMID:20470417  PMCID:PMC2880973
• Dorrell, M. I., Aguilar, E., Jacobson, R., Trauger, S. A., Friedlander, J., Siuzdak, G., Friedlander, M. Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy Glia  2010 58:43-54  DOI:10.1002/glia.20900  PMID:19544395  PMCID:PMC2814838
• Yanes, O., Clark, J., Wong, D. M., Patti, G. J., Sanchez-Ruiz, A., Benton, H. P., Trauger, S. A., Desponts, C., Ding, S., Siuzdak, G. Metabolic oxidation regulates embryonic stem cell differentiation Nature Chemical Biology  2010 6:411-417  DOI:10.1038/nchembio.364  PMID:20436487  PMCID:PMC2873061
• Cvetkovic, A., Menon, A. L., Thorgersen, M. P., Scott, J. W., Poole, F. L., Jenney, F. E., Lancaster, W. A., Praissman, J. L., Shanmukh, S., Vaccaro, B. J., Trauger, S. A., Kalisiak, E., et al. Microbial metalloproteomes are largely uncharacterized Nature  2010 466:779-782  DOI:10.1038/nature09265  PMID:20639861
• Patti, G. J., Shriver, L. P., Wassif, C. A., Woo, H. K., Uritboonthai, W., Apon, J., Manchester, M., Porter, F. D., Siuzdak, G. Nanostructure-initiator mass spectrometry (NIMS) imaging of brain cholesterol metabolites in Smith-Lemli-Opitz syndrome Neuroscience  2010 170:858-864  DOI:10.1016/j.neuroscience.2010.07.038  PMID:20670678  PMCID:PMC2952448
• Pendyala, G., Trauger, S. A., Siuzdak, G., Fox, H. S. Quantitative plasma proteomic profiling identifies the vitamin E binding protein afamin as a potential pathogenic factor in SIV induced CNS disease Journal of Proteome Research  2010 9:352-358  DOI:10.1021/pr900685u  PMID:19908921  PMCID:PMC2801767
• Kopp, F., Komatsu, T., Nomura, D. K., Trauger, S. A., Thomas, J. R., Siuzdak, G., Simon, G. M., Cravatt, B. F. The glycerophospho metabolome and its influence on amino acid homeostasis revealed by brain metabolomics of GDE1(-/-) mice Chemistry & Biology  2010 17:831-840  DOI:10.1016/j.chembiol.2010.06.009  PMID:20797612  PMCID:PMC2931592
• Dorrell, M. I., Aguilar, E., Jacobson, R., Yanes, O., Gariano, R., Heckenlively, J., Banin, E., Ramirez, G. A., Gasmi, M., Bird, A., Siuzdak, G., Friedlander, M. Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress Journal of Clinical Investigation  2009 119:611-623  DOI:10.1172/jci35977  PMID:19188685  PMCID:PMC2648679
• Pendyala, G., Trauger, S. A., Kalisiak, E., Ellis, R. J., Siuzdak, G., Fox, H. S. Cerebrospinal fluid proteomics reveals potential pathogenic changes in the brains of SIV-infected monkeys Journal of Proteome Research  2009 8:2253-2260  DOI:10.1021/pr800854t  PMID:19281240  PMCID:PMC2682714
• Koudelka, K. J., Destito, G., Plummer, E. M., Trauger, S. A., Siuzdak, G., Manchester, M. Endothelial targeting of cowpea mosaic virus (CPMV) via surface vimentin PLoS Pathogens  2009 5:e1000417  DOI:10.1371/journal.ppat.1000417  PMID:19412526  PMCID:PMC2670497
• Zhou, H. Y., Wu, S. L., Joo, J. Y., Zhu, S. Y., Han, D. W., Lin, T. X., Trauger, S., Bien, G., Zhu, Y., Yao, S., Siuzdak, G. Generation of induced pluripotent stem cells using recombinant proteins Cell Stem Cell  2009 4:381-384  DOI:10.1016/j.stem.2009.04.005  PMID:19398399
• Kalisiak, J., Trauger, S. A., Kalisiak, E., Morita, H., Fokin, V. V., Adams, M. W. W., Sharpless, K. B., Siuzdak, G. Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach Journal of the American Chemical Society  2009 131:378-386  DOI:10.1021/ja808172n  PMID:19055353  PMCID:PMC2735399
• Wikoff, W. R., Anfora, A. T., Liu, J., Schultz, P. G., Lesley, S. A., Peters, E. C., Siuzdak, G. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites Proceedings of the National Academy of Sciences of the United States of America  2009 106:3698-3703  DOI:10.1073/pnas.0812874106  PMID:19234110  PMCID:PMC2656143
• Yanes, O., Woo, H. K., Northen, T. R., Oppenheimer, S. R., Shriver, L., Apon, J., Estrada, M. N., Potchoiba, M. J., Steenwyk, R., Manchester, M., Siuzdak, G. Nanostructure initiator mass spectrometry: Tissue imaging and direct biofluid analysis Analytical Chemistry  2009 81:2969-2975  DOI:10.1021/ac802576q  PMID:19301920  PMCID:PMC2676195
• Menon, A. L., Poole, F. L., Cvetkovic, A., Trauger, S. A., Kalisiak, E., Scott, J. W., Shanmukh, S., Praissman, J., Jenney, F. E., Wikoff, W. R., Apon, J. V., Siuzdak, G., et al. Novel multiprotein complexes identified in the hyperthermophilic archaeon pyrococcus furiosus by non-denaturing fractionation of the native proteome Molecular & Cellular Proteomics  2009 8:735-751  DOI:10.1074/mcp.M800246-MCP200  PMID:19043064  PMCID:PMC2668238
• Woo, H. K., Go, E. P., Hoang, L., Trauger, S. A., Bowen, B., Siuzdak, G., Northen, T. R. Phosphonium labeling for increasing metabolomic coverage of neutral lipids using electrospray ionization mass spectrometry Rapid Communications in Mass Spectrometry  2009 23:1849-1855  DOI:10.1002/rcm.4076  PMID:19449318  PMCID:PMC3052201
• Wikoff, W. R., Kalisak, E., Trauger, S., Manchester, M., Siuzdak, G. Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response Journal of Proteome Research  2009 8:3578-3587  DOI:10.1021/pr900275p  PMID:19496611  PMCID:PMC3437991
• Crews, B., Wikoff, W. R., Patti, G. J., Woo, H. K., Kalisiak, E., Heideker, J., Siuzdak, G. Variability analysis of human plasma and cerebral spinal fluid reveals statistical significance of changes in mass spectrometry-based metabolomics data Analytical Chemistry  2009 81:8538-8544  DOI:10.1021/ac9014947  PMID:19764780  PMCID:PMC3058611
• Northen, T. R., Lee, J. C., Hoang, L., Raymond, J., Hwang, D. R., Yannone, S. M., Wong, C. H., Siuzdak, G. A nanostructure-initiator mass spectrometry-based enzyme activity assay Proceedings of the National Academy of Sciences of the United States of America  2008 105:3678-3683  DOI:10.1073/pnas.0712332105  PMID:18319341  PMCID:PMC2268803
• Trauger, S. A., Kalisak, E., Kalisiak, J., Morita, H., Weinberg, M. V., Menon, A. L., Poole, F. L., Adams, M. W. W., Siuzdak, G. Correlating the transcriptome, proteome, and metabolome in the environmental adaptation of a hyperthermophile Journal of Proteome Research  2008 7:1027-1035  DOI:10.1021/pr700609j  PMID:18247545
• Wikoff, W. R., Pendyala, G., Siuzdak, G., Fox, H. S. Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques Journal of Clinical Investigation  2008 118:2661-2669  DOI:10.1172/jci34138  PMID:18521184  PMCID:PMC2398736
• O'Maille, G., Go, E. P., Hoang, L., Want, E. J., Smith, C., O'Maille, P., Nordstrom, A., Morita, H., Qin, C., Uritboonthai, W., Apon, J., Moore, R., et al. Metabolomics relative quantitation with mass spectrometry using chemical derivatization and isotope labeling Spectroscopy-an International Journal  2008 22:327-343  DOI:10.3233/spe-2008-0361
• Nordstrom, A., Want, E., Northen, T., Lehtio, J., Siuzdak, G. Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics Analytical Chemistry  2008 80:421-429  DOI:10.1021/ac:701982e  PMID:18085752
• Eraly, S. A., Vallon, V., Rieg, T., Gangoiti, J. A., Wikoff, W. R., Siuzdak, G., Barshop, B. A., Nigam, S. K. Multiple organic anion transporters contribute to net renal excretion of uric acid Physiological Genomics  2008 33:180-192  DOI:10.1152/physiolgenomics.00207.2007  PMID:18270321  PMCID:PMC3016923
• Woo, H. K., Northen, T. R., Yanes, O., Siuzdak, G. Nanostructure-initiator mass spectrometry: a protocol for preparing and applying NIMS surfaces for high-sensitivity mass analysis Nature Protocols  2008 3:1341-1349  DOI:10.1038/nprot.2008.110  PMID:18714302
• Vallon, V., Eraly, S. A., Wikoff, W. R., Rieg, T., Kaler, G., Truong, D. M., Ahn, S. Y., Mahapatra, N. R., Mahata, S. K., Gangoiti, J. A., Wu, W., Barshop, B. A., et al. Organic anion transporter 3 contributes to the regulation of blood pressure Journal of the American Society of Nephrology  2008 19:1732-1740  DOI:10.1681/asn.2008020180  PMID:18508962  PMCID:PMC2518443
• Bunner, A. E., Trauger, S. A., Siuzdak, G., Williamson, J. R. Quantitative ESI-TOF analysis of macromolecular assembly kinetics Analytical Chemistry  2008 80:9379-9386  DOI:10.1021/ac8020505  PMID:19007188  PMCID:PMC2735594
• Benton, H. P., Wong, D. M., Trauger, S. A., Siuzdak, G. XCMS2: Processing tandem mass spectrometry data for metabolite identification and structural characterization Analytical Chemistry  2008 80:6382-6389  DOI:10.1021/ac800795f  PMID:18627180  PMCID:PMC2728033
• Pendyala, G., Want, E. J., Webb, W., Siuzdak, G., Fox, H. S. Biomarkers for neuroaids: The widening scope of metabolomics Journal of Neuroimmune Pharmacology  2007 2:72-80  DOI:10.1007/s11481-006-9041-3  PMID:18040828
• Northen, T. R., Yanes, O., Northen, M. T., Marrinucci, D., Uritboonthai, W., Apon, J., Golledge, S. L., Nordstrom, A., Siuzdak, G. Clathrate nanostructures for mass spectrometry Nature  2007 449:1033-1036  DOI:10.1038/nature06195  PMID:17960240
• Lissauer, M. E., Johnson, S. B., Siuzdak, G., Bochicchio, G., Whiteford, C., Nussbaumer, B., Moore, R., Scalea, T. M. Coagulation and complement protein differences between septic and uninfected systemic inflammatory response syndrome patients Journal of Trauma-Injury Infection and Critical Care  2007 62:1082-1092  DOI:10.1097/TA.0b013e31804d23e1  PMID:17495706
• Want, E. J., Nordstrom, A., Morita, H., Siuzdak, G. From exogenous to endogenous: The inevitable imprint of mass spectrometry in metabolomics Journal of Proteome Research  2007 6:459-468  DOI:10.1021/pr060505+  PMID:17269703
• Northen, T. R., Woo, H. K., Northen, M. T., Nordstrom, A., Uritboonthail, W., Turner, K. L., Siuzdak, G. High surface area of porous silicon drives desorption of intact molecules Journal of the American Society for Mass Spectrometry  2007 18:1945-1949  DOI:10.1016/j.jasms.2007.08.009  PMID:17881245  PMCID:PMC2080661
• Wikoff, W. R., Gangoiti, J. A., Barshop, B. A., Siuzdak, G. Metabolomics identifies perturbations in human disorders of propionate metabolism Clinical Chemistry  2007 53:2169-2176  DOI:10.1373/clinchem.2007.089011  PMID:17951291
• Mutch, D. M., O'Maille, G., Wikoff, W. R., Wiedmer, T., Sims, P. J., Siuzdak, G. Mobilization of pro-inflammatory lipids in obese plscr3-deficient mice Genome Biology  2007 8:R38  DOI:10.1186/gb-2007-8-3-r38  PMID:17355638  PMCID:PMC1868938
• Go, E. P., Uritboonthai, W., Apon, J. V., Trauger, S. A., Nordstrom, A., O'Maille, G., Brittain, S. M., Peters, E. C., Siuzdak, G. Selective metabolite and peptide capture/mass detection using fluorous affinity tags Journal of Proteome Research  2007 6:1492-1499  DOI:10.1021/pr060608s  PMID:17343404  PMCID:PMC2530906
• Steenwyk, R. C., Hutzler, J. M., Sams, J., Shen, Z. X., Siuzdak, G. Atmospheric pressure desorption/ionization on silicon ion trap mass spectrometry applied to the quantitation of midazolam in rat plasma and determination of midazolam 1 '-hydroxylation kinetics in human liver microsomes Rapid Communications in Mass Spectrometry  2006 20:3717-3722  DOI:10.1002/rcm.2796  PMID:17117443
• Go, E. P., Wikoff, W. R., Shen, Z. X., O'Maille, G., Morita, H., Conrads, T. P., Nordstrom, A., Trauger, S. A., Uritboonthai, W., Lucas, D. A., Chan, K. C., Veenstra, T. D., et al. Mass spectrometry reveals specific and global molecular transformations during viral infection Journal of Proteome Research  2006 5:2405-2416  DOI:10.1021/pr060215t  PMID:16944953  PMCID:PMC2566936
• Nordstrom, A., O'Maille, G., Qin, C., Siuzdak, G. Nonlinear data alignment for uplc-ms and hplc-ms based metabolomics: Quantitative analysis of endogenous and exogenous metabolites in human serum Analytical Chemistry  2006 78:3289-3295  DOI:10.1021/ac060245f  PMID:16689529  PMCID:PMC3705959
• Want, E. J., Smith, C. A., Qin, C. A., VanHorne, K. C., Siuzdak, G. Phospholipid capture combined with non-linear chromatographic correction for improved serum metabolite profiling Metabolomics  2006 2:145-154  DOI:10.1007/s11306-006-0028-0
• Lee, J. C., Wit, C. Y., Apon, J. V., Siuzdak, G., Wong, C. H. Reactivity-based one-pot synthesis of the tumor-associated antigen n3 minor octasaccharide for the development of a photocleavable dios-ms sugar array Angewandte Chemie-International Edition  2006 45:2753-2757  DOI:10.1002/anie.200504067  PMID:16548041
• Shen, Z. X., Want, E. J., Chen, W., Keating, W., Nussbaumer, W., Moore, R., Gentle, T. M., Siuzdak, G. Sepsis plasma protein profiling with immunodepletion, three-dimensional liquid chromatography tandem mass spectrometry, and spectrum counting Journal of Proteome Research  2006 5:3154-3160  DOI:10.1021/pr060327k  PMID:17081067
• Want, E. J., O'Maille, G., Smith, C. A., Brandon, T. R., Uritboonthai, W., Qin, C., Trauger, S. A., Siuzdak, G. Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry Analytical Chemistry  2006 78:743-752  DOI:10.1021/ac051312t  PMID:16448047
• Nordstrom, A., Apon, J. V., Uritboonthal, W., Go, E. P., Siuzdak, G. Surfactant-enhanced desorption/ionization on silicon mass spectrometry Analytical Chemistry  2006 78:272-278  DOI:10.1021/ac051398q  PMID:16383337
• Smith, C. A., Want, E. J., O'Maille, G., Abagyan, R., Siuzdak, G. Xcms: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification Analytical Chemistry  2006 78:779-787  DOI:10.1021/ac051437y  PMID:16448051
• Talkington, M. W. T., Siuzdak, G., Williamson, J. R. An assembly landscape for the 30S ribosomal subunit Nature  2005 438:628-632  DOI:10.1038/nature04261  PMID:16319883  PMCID:PMC1444899
• Go, E. P., Apon, J. V., Luo, G. H., Saghatelian, A., Daniels, R. H., Sahi, V., Dubrow, R., Cravatt, B. F., Vertes, A., Siuzdak, G. Desorption/ionization on silicon nanowires Analytical Chemistry  2005 77:1641-1646  DOI:10.1021/ac048460o  PMID:15762567
• Smith, C. A., O'Maille, G., Want, E. J., Qin, C., Trauger, S. A., Brandon, T. R., Custodio, D. E., Abagyan, R., Siuzdak, G. METLIN - a metabolite mass spectral database Therapeutic Drug Monitoring  2005 27:747-751  DOI:10.1097/01.ftd.0000179845.53213.39  PMID:16404815
• Bothner, B., Taylor, D., Jun, B., Lee, K. K., Siuzdak, G., Schlutz, C. P., Johnson, J. E. Maturation of a tetravirus capsid alters the dynamic properties and creates a metastable complex Virology  2005 334:17-27  DOI:10.1016/j.virol.2005.01.017  PMID:15749119
• Lacy, E. R., Wang, Y. F., Post, J., Nourse, A., Webb, W., Mapelli, M., Musacchio, A., Siuzdak, G., Kriwacki, R. W. Molecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell division Journal of Molecular Biology  2005 349:764-773  DOI:10.1016/j.jmb.2005.04.019  PMID:15890360
• Lowe, R., Go, E. P., Tong, G. C., Voelcker, N. H., Siuzdak, G. Monitoring edta and endogenous metabolite biomarkers from serum with mass spectrometry Spectroscopy-an International Journal  2005 19:137-146
• Luo, G. H., Chen, Y., Siuzdak, G., Vertes, A. Surface modification and laser pulse length effects on internal energy transfer in dios Journal of Physical Chemistry B  2005 109:24450-24456  DOI:10.1021/jp054311d  PMID:16375447
• Want, E. J., Cravatt, B. F., Siuzdak, G. The expanding role of mass spectrometry in metabolite profiling and characterization ChemBioChem  2005 6:1941-1951  DOI:10.1002/cbic.200500151  PMID:16206229
• Shen, Z. X., Thomas, J. J., Siuzdak, G., Blackledge, R. D. A case study on forensic polymer analysis by dios-ms: The suspect who gave us the slip (r) Journal of Forensic Sciences  2004 49:1028-1035  PMID:15461106
• Shen, Z. X., Go, E. P., Gamez, A., Apon, J. V., Fokin, V., Greig, M., Ventura, M., Crowell, J. E., Blixt, O., Paulson, J. C., Stevens, R. C., Finn, M. G., et al. A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a desorption/ionization on silicon (DIOS) platform ChemBioChem  2004 5:921-927  DOI:10.1002/cbic.200400008  PMID:15239048
• Meng, J. C., Siuzdak, G., Finn, M. G. Affinity mass spectrometry from a tailored porous silicon surface Chemical Communications  2004 2108-2109  DOI:10.1039/b408200a
• Saghatelian, A., Trauger, S. A., Want, E. J., Hawkins, E. G., Siuzdak, G., Cravatt, B. F. Assignment of endogenous substrates to enzymes by global metabolite profiling Biochemistry  2004 43:14332-14339  DOI:10.1021/bi0480335  PMID:15533037
• Meng, J. C., Averbuj, C., Lewis, W. G., Siuzdak, G., Finn, M. G. Cleavable linkers for porous silicon-based mass spectrometry Angewandte Chemie-International Edition  2004 43:1255-1260  DOI:10.1002/anie.200352803  PMID:14991792
• Thomas, J. J., Bothner, B., Traina, J., Benner, W. H., Siuzdak, G. Electrospray ion mobility spectrometry of intact viruses Spectroscopy-an International Journal  2004 18:31-36
• Bothner, B., Siuzdak, G. Electrospray ionization of a whole virus: Analyzing mass, structure, and viability ChemBioChem  2004 5:258-260  DOI:10.1002/cbic.200300754  PMID:14997515
• Trauger, S. A., Go, E. P., Shen, Z. X., Apon, J. V., Compton, B. J., Bouvier, E. S. P., Finn, M. G., Siuzdak, G. High sensitivity and analyte capture with desorption/ionization mass spectrometry on silylated porous silicon Analytical Chemistry  2004 76:4484-4489  DOI:10.1021/ac049657j  PMID:15283591
• Wu, E., Trauger, S. A., Pache, L., Mullen, T. M., Von Seggern, D. J., Siuzdak, G., Nemerow, G. R. Membrane cofactor protein is a receptor for adenoviruses associated with epidemic keratoconjunctivitis Journal of Virology  2004 78:3897-3905  DOI:10.1128/jvi.78.8.3897-3905.2004  PMID:15047806
• Kriwacki, R., Reisdorph, N., Siuzdak, G. Protein structure characterization with mass spectrometry Spectroscopy-an International Journal  2004 18:37-47
• Trauger, S. A., Wu, E., Bark, S. J., Nemerow, G. R., Siuzdak, G. The identification of an adenovirus receptor by using affinity capture and mass spectrometry ChemBioChem  2004 5:1095-1099  DOI:10.1002/cbic.200400037  PMID:15300833
• Lewis, W. G., Shen, Z. X., Finn, M. G., Siuzdak, G. Desorption/ionization on silicon (DIOS) mass spectrometry: background and applications International Journal of Mass Spectrometry  2003 226:107-116  DOI:10.1016/s1387-3806(02)00973-9
• Go, E. P., Prenni, J. E., Wei, J., Jones, A., Hall, S. C., Witkowska, H. E., Shen, Z. X., Siuzdak, G. Desorption/ionization on silicon time-of-flight/time-of-flight mass spectrometry Analytical Chemistry  2003 75:2504-2506  DOI:10.1021/ac026253n  PMID:12918997
• Reisdorph, N., Thomas, J. J., Katpally, U., Chase, E., Harris, K., Siuzdak, G., Smith, T. J. Human rhinovirus capsid dynamics is controlled by canyon flexibility Virology  2003 314:34-44  DOI:10.1016/s0042-6822(03)00452-5  PMID:14517058
• Trauger, S. A., Junker, T., Siuzdak, G. Investigating viral proteins and intact viruses with mass spectrometry Modern Mass Spectrometry  2003 225:265-282  DOI:10.1007/b10476
• Want, E., Greig, M., Compton, B., Bolanos, B., Siuzdak, G. Mass spectrometry in high throughput analysis Spectroscopy-an International Journal  2003 17:663-680
• Compton, B. J., Siuzdak, G. Mass spectrometry in nucleic acid, carbohydrate and steroid analysis Spectroscopy-an International Journal  2003 17:699-713
• Yao, S., Meng, J. C., Siuzdak, G., Finn, M. G. New catalysts for the asymmetric hydrosilylation of ketones discovered by mass spectrometry screening Journal of Organic Chemistry  2003 68:2540-2546  DOI:10.1021/jo026365e  PMID:12662022
• Prenni, J. E., Shen, Z. X., Trauger, S., Chen, W., Siuzdak, G. Protein characterization using liquid chromatography desorption ionization on silicon mass spectrometry (lc-dios-ms) Spectroscopy-an International Journal  2003 17:693-698
• Meyers, A., Trauger, S., Webb, W., Reisdorph, N., Wranik, C., Peters, E., Siuzdak, G. Protein identification and profiling with mass spectrometry Spectroscopy-an International Journal  2003 17:1-15
• Go, E. P., Shen, Z. X., Harris, K., Siuzdak, G. Quantitative analysis with desorption/ionization on silicon mass spectrometry using electrospray deposition Analytical Chemistry  2003 75:5475-5479  DOI:10.1021/ac034376h  PMID:14710827
• Want, E., Compton, B. J., Hollenbeck, T., Siuzdak, G. The application of mass spectrometry in pharmacokinetics studies Spectroscopy-an International Journal  2003 17:681-691
• Sonderegger, M., Staniszewski, K., Meyers, A., Siuzdak, G. A bioinformatics approach for mass spectrometry data processing: Applications to proteomics and small molecule analysis Spectroscopy-an International Journal  2002 16:81-87
• Bothner, B., Carmitchel, L., Staniszewski, K., Sonderegger, M., Siuzdak, G. Biomolecule structure characterization in the gas phase using mass spectrometry Spectroscopy-an International Journal  2002 16:71-79
• Trauger, S. A., Webb, W., Siuzdak, G. Peptide and protein analysis with mass spectrometry Spectroscopy-an International Journal  2002 16:15-28
• Smith, T. J., Schmidt, T., Fang, J., Wu, J., Siuzdak, G., Stanley, C. A. The structure of apo human glutamate dehydrogenase details subunit communication and allostery Journal of Molecular Biology  2002 318:765-777  DOI:10.1016/s0022-2836(02)00161-4  PMID:12054821
• Thomas, J. J., Shen, Z. X., Blackledge, R., Siuzdak, G. Desorption-ionization on silicon mass spectrometry: An application in forensics Analytica Chimica Acta  2001 442:183-190  DOI:10.1016/s0003-2670(01)01107-2
• Thomas, J. J., Shen, Z. X., Crowell, J. E., Finn, M. G., Siuzdak, G. Desorption/ionization on silicon (dios): A diverse mass spectrometry platform for protein characterization Proceedings of the National Academy of Sciences of the United States of America  2001 98:4932-4937  DOI:10.1073/pnas.081069298  PMID:11296246  PMCID:PMC33141
• Shen, Z. X., Yao, S. L., Crowell, J. E., Siuzdak, G., Finn, M. G. Dios-mseed: A chip-based method for measurement of enantiomeric excess by kinetic resolution/mass spectrometry Israel Journal of Chemistry  2001 41:313-316  DOI:10.1560/tbxu-fd8h-fhm1-nr8h
• Bark, S. J., Muster, N., Yates, J. R., Siuzdak, G. High-temperature protein mass mapping using a thermophilic protease Journal of the American Chemical Society  2001 123:1774-1775  DOI:10.1021/ja002909n  PMID:11456785
• Fuerstenau, S. D., Benner, W. H., Thomas, J. J., Brugidou, C., Bothner, B., Siuzdak, G. Mass spectrometry of an intact virus Angewandte Chemie-International Edition  2001 40:542-544
• Shen, Z. X., Thomas, J. J., Averbuj, C., Broo, K. M., Engelhard, M., Crowell, J. E., Finn, M. G., Siuzdak, G. Porous silicon as a versatile platform for laser desorption/ionization mass spectrometry Analytical Chemistry  2001 73:612-619  DOI:10.1021/ac000746f  PMID:11217770
• Broo, K., Wei, J., Marshall, D., Brown, F., Smith, T. J., Johnson, J. E., Schneemann, A., Siuzdak, G. Viral capsid mobility: A dynamic conduit for inactivation Proceedings of the National Academy of Sciences of the United States of America  2001 98:2274-2277  DOI:10.1073/pnas.051598298  PMID:11226229  PMCID:PMC30128
• Thomas, J. J., Bakhtiar, R., Siuzdak, G. Mass spectrometry in viral proteomics Accounts of Chemical Research  2000 33:179-187  DOI:10.1021/ar9801200  PMID:10727207
• Bothner, B., Chavez, R., Wei, J., Strupp, C., Phung, Q., Schneemann, A., Siuzdak, G. Monitoring enzyme catalysis with mass spectrometry Journal of Biological Chemistry  2000 275:13455-13459  DOI:10.1074/jbc.275.18.13455  PMID:10788458
• Bothner, B., Schneemann, A., Marshall, D., Reddy, V., Johnson, J. E., Siuzdak, G. Crystallographically identical virus capsids display different properties in solution Nature Structural Biology  1999 6:114-116  PMID:10048920
• Wei, J., Buriak, J. M., Siuzdak, G. Desorption-ionization mass spectrometry on porous silicon Nature  1999 399:243-246  PMID:10353246
• Hollenbeck, T. P. E., Siuzdak, G., Blackledge, R. D. Electrospray and maldi mass spectrometry in the identification of spermicides in criminal investigations Journal of Forensic Sciences  1999 44:783-788  PMID:10432613
• Yang, C. Y., Gu, Z. W., Yang, M. L., Lin, S. N., Siuzdak, G., Smith, C. V. Identification of modified tryptophan residues in apolipoprotein b-100 derived from copper ion-oxidized low-density lipoprotein Biochemistry  1999 38:15903-15908  DOI:10.1021/bi991464g  PMID:10625456
• Schalley, C. A., Castellano, R. K., Brody, M. S., Rudkevich, D. M., Siuzdak, G., Rebek, J. Investigating molecular recognition by mass spectrometry: Characterization of calixarene-based self-assembling capsule hosts with charged guests Journal of the American Chemical Society  1999 121:4568-4579  DOI:10.1021/ja990276a
• Guo, J. H., Wu, J., Siuzdak, G., Finn, M. G. Measurement of enantiomeric excess by kinetic resolution and mass spectrometry Angewandte Chemie-International Edition  1999 38:1755-1758  DOI:10.1002/(sici)1521-3773(19990614)38:12<1755::aid-anie1755>3.3.co;2-h
• Chatman, K., Hollenbeck, T., Hagey, L., Vallee, M., Purdy, R., Weiss, F., Siuzdak, G. Nanoelectrospray mass spectrometry and precursor ion monitoring for quantitative steroid analysis and attomole sensitivity Analytical Chemistry  1999 71:2358-2363  DOI:10.1021/ac9806411  PMID:10405603
• Tsui, V., Garcia, C., Cavagnero, S., Siuzdak, G., Dyson, H. J., Wright, P. E. Quench-flow experiments combined with mass spectrometry show apomyoglobin folds through an obligatory intermediate Protein Science  1999 8:45-49  DOI:10.1110/ps.8.1.45  PMID:10210182  PMCID:PMC2144105
• Marmey, P., Bothner, B., Jacquot, E., de Kochko, A., Ong, C. A., Yot, P., Siuzdak, G., Beachy, R. N., Fauquet, C. M. Rice tungro bacilliform virus open reading frame 3 encodes a single 37-kda coat protein Virology  1999 253:319-326  DOI:10.1006/viro.1998.9519  PMID:9918890
• Takayama, S., Chung, S. J., Igarashi, Y., Ichikawa, Y., Sepp, A., Lechler, R. I., Wu, J., Hayashi, T., Siuzdak, G., Wong, C. H. Selective inhibition of β-1,4- and α-1,3-galactosyltransferases: donor sugar-nucleotide based approach Bioorganic & Medicinal Chemistry  1999 7:401-409  DOI:10.1016/s0968-0896(98)00249-1  PMID:10218835
• Schalley, C. A., Rivera, J. M., Martin, T., Santamaria, J., Siuzdak, G., Rebek, J. Structural examination of supramolecular architectures by electrospray ionization mass spectrometry European Journal of Organic Chemistry  1999 1999:1325-1331  DOI:10.1002/(SICI)1099-0690(199906)1999:6<1325::AID-EJOC1325>3.0.CO;2-6
• Lewis, J. K., Bothner, B., Smith, T. J., Siuzdak, G. Antiviral agent blocks breathing of the common cold virus Proceedings of the National Academy of Sciences of the United States of America  1998 95:6774-6778  DOI:10.1073/pnas.95.12.6774  PMID:9618488
• Owens, D. R., Bothner, B., Phung, Q., Harris, K., Siuzdak, G. Aspects of oligonucleotide and peptide sequencing with maldi and electrospray mass spectrometry Bioorganic & Medicinal Chemistry  1998 6:1547-1554  DOI:10.1016/s0968-0896(98)00098-4  PMID:9801826
• Bothner, B., Dong, X. F., Bibbs, L., Johnson, J. E., Siuzdak, G. Evidence of viral capsid dynamics using limited proteolysis and mass spectrometry Journal of Biological Chemistry  1998 273:673-676  DOI:10.1074/jbc.273.2.673  PMID:9422714
• Lewis, J. K., Bendahmane, M., Smith, T. J., Beachy, R. N., Siuzdak, G. Identification of viral mutants by mass spectrometry Proceedings of the National Academy of Sciences of the United States of America  1998 95:8596-8601  DOI:10.1073/pnas.95.15.8596  PMID:9671723
• Siuzdak, G. Probing viruses with mass spectrometry Journal of Mass Spectrometry  1998 33:203-211  DOI:10.1002/(sici)1096-9888(199803)33:3<203::aid-jms653>3.0.co;2-q  PMID:9538522
• Siuzdak, G. What's your frequently asked mass spec question? R&D Magazine  1998 40:37-37
• Wu, J., Chatman, K., Harris, K., Siuzdak, G. An automated maldi mass spectrometry approach for optimizing cyclosporin extraction and quantitation Analytical Chemistry  1997 69:3767-3771  DOI:10.1021/ac970276y  PMID:9302875
• Takayama, S., Martin, R., Wu, J., Laslo, K., Siuzdak, G., Wong, C. H. Chemoenzymatic preparation of novel cyclic imine sugars and rapid biological activity evaluation using electrospray mass spectrometry and kinetic analysis Journal of the American Chemical Society  1997 119:8146-8151  DOI:10.1021/ja971695f
• Kriwacki, R. W., Wu, J., Tennant, L., Wright, P. E., Siuzdak, G. Probing protein structure using biochemical and biophysical methods - proteolysis, matrix-assisted laser desorption/ionization mass spectrometry, high-performance liquid chromatography and size-exclusion chromatography of p21(waf1/cip1/sdi1) Journal of Chromatography A  1997 777:23-30  DOI:10.1016/s0021-9673(97)00527-x  PMID:9297835
• Wu, J., Takayama, S., Wong, C. H., Siuzdak, G. Quantitative electrospray mass spectrometry for the rapid assay of enzyme inhibitors Chemistry & Biology  1997 4:653-657  DOI:10.1016/s1074-5521(97)90220-9  PMID:9331404
• Chang, H. T., Chen, C. T., Kondo, T., Siuzdak, G., Sharpless, K. B. Asymmetric dihydroxylation enables rapid construction of chiral dendrimers based on 1,2-diols Angewandte Chemie-International Edition  1996 35:182-186  DOI:10.1002/anie.199601821
• Fitzgerald, M. C., Siuzdak, G. Biochemical mass spectrometry: Worth the weight? Chemistry & Biology  1996 3:707-715  DOI:10.1016/s1074-5521(96)90245-8  PMID:8939685
• Fitzgerald, M. C., Harris, K., Shevlin, C. G., Siuzdak, G. Direct characterization of solid phase resin-bound molecules by mass spectrometry Bioorganic & Medicinal Chemistry Letters  1996 6:979-982  DOI:10.1016/0960-894x(96)00152-7
• Siuzdak, G., Bothner, B., Yeager, M., Brugidou, C., Fauquet, C. M., Hoey, K., Chang, C. M. Mass spectrometry and viral analysis Chemistry & Biology  1996 3:45-48  DOI:10.1016/s1074-5521(96)90083-6  PMID:8807827
• Kriwacki, R. W., Wu, J., Siuzdak, G., Wright, P. E. Probing protein/protein interactions with mass spectrometry and isotopic labeling: Analysis of the p21/cdk2 complex Journal of the American Chemical Society  1996 118:5320-5321  DOI:10.1021/ja960752m
• Cravatt, B. F., Prosperogarcia, O., Siuzdak, G., Gilula, N. B., Henriksen, S. J., Boger, D. L., Lerner, R. A. Chemical characterization of a family of brain lipids that induce sleep Science  1995 268:1506-1509  DOI:10.1126/science.7770779  PMID:7770779
• Krebs, J. F., Siuzdak, G., Dyson, H. J., Stewart, J. D., Benkovic, S. J. Detection of a catalytic antibody species acylated at the active site by electrospray mass spectrometry Biochemistry  1995 34:720-723  DOI:10.1021/bi00003a002  PMID:7827028
• Siuzdak, G., Bothner, B. Gas-phase micelles Angewandte Chemie-International Edition  1995 34:2053-2055  DOI:10.1002/anie.199520531
• Bothner, B., Chatman, K., Sarkisian, M., Siuzdak, G. Liquid-chromatography mass-spectrometry of antisense oligonucleotides Bioorganic & Medicinal Chemistry Letters  1995 5:2863-2868  DOI:10.1016/0960-894x(95)00499-j
• Siuzdak, G., Krebs, J. F., Benkovic, S. J., Dyson, H. J. Binding of hapten to a single chain catalytic antibody demonstrated by electrospray mass spectrometry Journal of the American Chemical Society  1994 116:7937-7938  DOI:10.1021/ja00096a077
• Lerner, R. A., Siuzdak, G., Prosperogarcia, O., Henriksen, S. J., Boger, D. L., Cravatt, B. F. Cerebrodiene: A brain lipid isolated from sleep-deprived cats Proceedings of the National Academy of Sciences of the United States of America  1994 91:9505-9508  DOI:10.1073/pnas.91.20.9505  PMID:7937797  PMCID:PMC44841
• Stewart, J. D., Krebs, J. F., Siuzdak, G., Berdis, A. J., Smithrud, D. B., Benkovic, S. J. Dissection of an antibody-catalyzed reaction Proceedings of the National Academy of Sciences of the United States of America  1994 91:7404-7409  DOI:10.1073/pnas.91.16.7404  PMID:8052597
• Siuzdak, G., Zheng, Z. L., Rhamphal, J. Y., Ichikawa, Y., Nicolaou, K. C., Gaeta, F. C. A., Chatman, K. S., Wong, C. H. Examination of the sialyl-lewis-x calcium complex by electrospray mass-spectrometry Bioorganic & Medicinal Chemistry Letters  1994 4:2863-2866  DOI:10.1016/s0960-894x(01)80829-5
• Crano, J., Knowles, D., Kwiatkowski, P., Flood, T., Ross, R., Chiang, L., Lasch, J., Chadha, R., Siuzdak, G. Structure of three novel photochromic compounds; X-ray crystallographic and theoretical studies Acta Crystallographica Section B-Structural Science  1994 50:772-779  DOI:10.1107/s0108768194005938
• Siuzdak, G. The emergence of mass-spectrometry in biochemical-research Proceedings of the National Academy of Sciences of the United States of America  1994 91:11290-11297  DOI:10.1073/pnas.91.24.11290  PMID:7972052
• Rideout, D., Bustamante, A., Siuzdak, G. Cationic drug analysis using matrix-assisted laser-desorption ionization mass-spectrometry - application to influx kinetics, multidrug-resistance, and intracellular chemical-change Proceedings of the National Academy of Sciences of the United States of America  1993 90:10226-10229  DOI:10.1073/pnas.90.21.10226  PMID:8234281
• Siuzdak, G., Ichikawa, Y., Caulfield, T. J., Munoz, B., Wong, C. H., Nicolaou, K. C. Evidence of ca2+-dependent carbohydrate association through ion spray mass-spectrometry Journal of the American Chemical Society  1993 115:2877-2881  DOI:10.1021/ja00060a040
• Siuzdak, G., Wendeborn, S. V., Nicolaou, K. C. Cationization of organometallo carbonyl compounds by fast ion bombardment International Journal of Mass Spectrometry and Ion Processes  1992 112:79-91  DOI:10.1016/0168-1176(92)87033-b
• Siuzdak, G., Belbruno, J. J. Multiphoton ionization of nitrobenzene in nonaqueous solutions - characterization of the cation and ion-molecule chemistry Laser Chemistry  1991 11:83-93  DOI:10.1155/lc.11.83
• Siuzdak, G., North, S., Belbruno, J. J. Multiphoton ionization of phenol in nonaqueous solutions - characterization of the cation and ion molecule chemistry Journal of Physical Chemistry  1991 95:5186-5190  DOI:10.1021/j100166a050
• Belbruno, J. J., Siuzdak, G. Rempi-ms - application to the study of the gas-phase dynamics of radical cations Institute of Physics Conference Series  1991 177-180
• Belbruno, J. J., Siuzdak, G. Resonant ionization in solution - initiation of ion-molecule chemistry by rempi Institute of Physics Conference Series  1991 351-354
• Siuzdak, G., Belbruno, J. J. Laser multiphoton dissociation ionization of butylamines - competitive processes in radical cations Journal of Physical Chemistry  1990 94:4559-4565  DOI:10.1021/j100374a038
• Siuzdak, G., Belbruno, J. J. Multiphoton ionization studies of amines with uv-vis lasers Applied Physics B-Photophysics and Laser Chemistry  1990 50:221-226  DOI:10.1007/bf00357287
• Belbruno, J. J., Siuzdak, G., North, S. Multiphoton-induced chemistry of phenol in hexane at 266 nm Chemical Physics Letters  1990 166:167-172  DOI:10.1016/0009-2614(90)87271-r
• Belbruno, J. J., Siuzdak, G., North, S. Uv multiphoton induced chemistry of nitrobenzene in solution Laser Chemistry  1990 10:177-184  DOI:10.1155/1990/42676
• Marzzacco, C. J., Deckey, G., Colarulli, R., Siuzdak, G., Halpern, A. M. Excited-state protonation and photophysical properties of azaphenanthrenes Journal of Physical Chemistry  1989 93:2935-2939  DOI:10.1021/j100345a018