recent publications
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academic article
- Hernandez, L. W., Sarlah, D. Empowering synthesis of complex natural products Chemistry-a European Journal 2019 DOI:10.1002/chem.201901808 PMID:31194262
- Tang, C., Okumura, M., Zhu, Y., Hooper, A. R., Zhou, Y., Lee, Y. H., Sarlah, D. Palladium-catalyzed dearomative syn-1,4-carboamination with Grignard reagents Angewandte Chemie-International Edition 2019 58:10245-10249 DOI:10.1002/anie.201905021 PMID:31090252 PMCID:PMC6640109
- Dennis, D. G., Okumura, M., Sarlah, D. Synthesis of (+/-)-idarubicinone via global functionalization of tetracene Journal of the American Chemical Society 2019 141:10193-10198 DOI:10.1021/jacs.9b05370 PMID:31244190
- Bingham, T. W., Hernandez, L. W., Olson, D. G., Svec, R. L., Hergenrother, P. J., Sarlah, D. Enantioselective synthesis of isocarbostyril alkaloids and analogs using catalytic dearomative functionalization of benzene Journal of the American Chemical Society 2019 141:657-670 DOI:10.1021/jacs.8b12123 PMID:30520639 PMCID:PMC6488038
- Wertjes, W. C., Okumura, M., Sarlah, D. Palladium-catalyzed dearomative syn-1,4-diamination Journal of the American Chemical Society 2019 141:163-167 DOI:10.1021/jacs.8b13030 PMID:30566338 PMCID:PMC6488036
- Wertjes, W. C., Southgate, E. H., Sarlah, D. Recent advances in chemical dearomatization of nonactivated arenes Chemical Society Reviews 2018 47:7996-8017 DOI:10.1039/c8cs00389k PMID:30073226
- Hernandez, L. W., Klockner, U., Pospech, J., Hauss, L., Sarlah, D. Nickel-catalyzed dearomative trans-1,2-carboamination Journal of the American Chemical Society 2018 140:4503-4507 DOI:10.1021/jacs.8b01726 PMID:29544244 PMCID:PMC5971658
- Okumura, M., Sarlah, D. Arenophile-mediated dearomative functionalization strategies Synlett 2018 29:845-855 DOI:10.1055/s-0036-1591940
- Sarlah, D., Okumura, M., Shved, A. Palladium-catalyzed dearomative syn-1,4-carboamination Synlett 2018 29:A40-A43
- Sarlah, D., Okumura, M., Shved, A. Palladium-catalyzed dearomative syn-1,4-carboamination Synthesis-Stuttgart 2018 50:A40-A43 DOI:10.1055/s-0036-1591457 PMID:29183109 PMCID:PMC5971112
- Okumura, M., Shved, A. S., Sarlah, D. Palladium-catalyzed dearomative syn-1,4-carboamination Journal of the American Chemical Society 2017 139:17787-17790 DOI:10.1021/jacs.8b13030 PMID:29183109 PMCID:PMC5971112
- Hernandez, L. W., Pospech, J., Klockner, U., Bingham, T. W., Sarlah, D. Synthesis of (+)-pancratistatins via catalytic desymmetrization of benzene Journal of the American Chemical Society 2017 139:15656-15659 DOI:10.1021/jacs.7b10351 PMID:29059521 PMCID:PMC5960067
- Schafroth, M. A., Rummelt, S. M., Sarlah, D., Carreira, E. M. Enantioselective iridium-catalyzed allylic cyclizations Organic Letters 2017 19:3235-3238 DOI:10.1021/acs.orglett.7b01346 PMID:28573860
- Southgate, E. H., Holycross, D. R., Sarlah, D. Total synthesis of lycoricidine and narciclasine by chemical dearomatization of bromobenzene Angewandte Chemie-International Edition 2017 56:15049-15052 DOI:10.1002/anie.201709712 PMID:29024240 PMCID:PMC5971115
- Okumura, M., Huynh, S. M. N., Pospech, J., Sarlah, D. Arenophile-mediated dearomative reduction Angewandte Chemie-International Edition 2016 55:15910-15914 DOI:10.1002/anie.201609686 PMID:27879027 PMCID:PMC6043355
- Southgate, E. H., Pospech, J., Fu, J., Holycross, D. R., Sarlah, D. Dearomative dihydroxylation with arenophiles Nature Chemistry 2016 8:922-928 DOI:10.1038/nchem.2594 PMID:27657867 PMCID:PMC5971114
- Sarlah, D. Organic chemistry: No double bond left behind Nature 2016 531:453-454 PMID:27008963
- Sarlah, D., Juranovic, A., Kozar, B., Rejc, L., Golobic, A., Petric, A. Synthesis of naphthalene-based push-pull molecules with a heteroaromatic electron acceptor Molecules 2016 21 DOI:10.3390/molecules21030267 PMID:26950099
- Ungarean, C. N., Southgate, E. H., Sarlah, D. Enantioselective polyene cyclizations Organic & Biomolecular Chemistry 2016 14:5454-5467 DOI:10.1039/c6ob00375c PMID:27143099
- Hamilton, J. Y., Sarlah, D., Carreira, E. M. Iridium-catalyzed enantioselective allylic alkylation with functionalized organozinc bromides Angewandte Chemie-International Edition 2015 54:7644-7647 DOI:10.1002/anie.201501851 PMID:25969352
- Shemet, A., Sarlah, D., Carreira, E. M. Stereochemical studies of the opening of chloro vinyl epoxides: cyclic chloronium ions as intermediates Organic Letters 2015 17:1878-1881 DOI:10.1021/acs.orglett.5b00558 PMID:25811099
- Schafroth, M. A., Zuccarello, G., Krautwald, S., Sarlah, D., Carreira, E. M. Stereodivergent total synthesis of Δ9-tetrahydrocannabinols Angewandte Chemie - International Edition 2014 53:13898-13901 DOI:10.1002/anie.201408380 PMID:25303495
- Hamilton, J. Y., Hauser, N., Sarlah, D., Carreira, E. M. Iridium-catalyzed enantioselective allyl-allylsilane cross-coupling Angewandte Chemie - International Edition 2014 53:10759-10762 DOI:10.1002/anie.201406077 PMID:25111443
- Hamilton, J. Y., Sarlah, D., Carreira, E. M. Iridium-catalyzed enantioselective allyl-alkene coupling Journal of the American Chemical Society 2014 136:3006-3009 DOI:10.1021/ja412962w PMID:24521052
- Krautwald, S., Schafroth, M. A., Sarlah, D., Carreira, E. M. Stereodivergent α-allylation of linear aldehydes with dual iridium and amine catalysis Journal of the American Chemical Society 2014 136:3020-3023 DOI:10.1021/ja5003247 PMID:24506196
- Lin, T. Y., Chin, C. R., Everitt, A. R., Clare, S., Perreira, J. M., Savidis, G., Aker, A. M., John, S. P., Sarlah, D., Carreira, E. M., Elledge, S. J., Kellam, P., et al. Amphotericin B increases influenza A virus infection by preventing IFITM3-mediated restriction Cell Reports 2013 5:895-908 DOI:10.1016/j.celrep.2013.10.033 PMID:24268777 PMCID:PMC3898084
- Hamilton, J. Y., Sarlah, D., Carreira, E. M. Iridium-catalyzed enantioselective allylic alkynylation Angewandte Chemie - International Edition 2013 52:7532-7535 DOI:10.1002/anie.201302731 PMID:23712914
- Krautwald, S., Sarlah, D., Schafroth, M. A., Carreira, E. M. Enantio- and diastereodivergent dual catalysis: α-allylation of branched aldehydes Science 2013 340:1065-1068 DOI:10.1126/science.1237068 PMID:23723229
- Hamilton, J. Y., Sarlah, D., Carreira, E. M. Iridium-catalyzed enantioselective allylic vinylation Journal of the American Chemical Society 2013 135:994-997 DOI:10.1021/ja311422z PMID:23256708
- Schafroth, M. A., Sarlah, D., Krautwald, S., Carreira, E. M. Iridium-catalyzed enantioselective polyene cyclization Journal of the American Chemical Society 2012 134:20276-20278 DOI:10.1021/ja310386m PMID:23193947
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Nicolaou, K. C., Lu, M., Totokotsopoulos, S., Heretsch, P., Giguere, D., Sun, Y. P., Sarlah, D., Nguyen, T. H., Wolf, I. C., Smee, D. F., Day, C. W., Bopp, S., et al. Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents Journal of the American Chemical Society 2012 134:17320-17332 DOI:10.1021/ja308429f PMID:22978674 PMCID:PMC3490634
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Nicolaou, K. C., Sun, Y. P., Sarlah, D., Zhan, W. Q., Wu, T. R. Bioinspired synthesis of hirsutellones A, B, and C Organic Letters 2011 13:5708-5710 DOI:10.1021/ol202239u PMID:21913732 PMCID:PMC3207260
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Nicolaou, K. C., Totokotsopoulos, S., Giguere, D., Sun, Y. P., Sarlah, D. Total synthesis of epicoccin G Journal of the American Chemical Society 2011 133:8150-8153 DOI:10.1021/ja2032635 PMID:21548595 PMCID:PMC3102137
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Nicolaou, K. C., Sanchini, S., Sarlah, D., Lu, G., Wu, T. R., Nomura, D. K., Cravatt, B. F., Cubitt, B., de la Torre, J. C., Hessell, A. J., Burton, D. R. Design, synthesis, and biological evaluation of a biyouyanagin compound library Proceedings of the National Academy of Sciences of the United States of America 2011 108:6715-6720 DOI:10.1073/pnas.1015258108 PMID:21245351 PMCID:PMC3084107
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Nicolaou, K. C., Sun, Y. P., Korman, H., Sarlah, D. Asymmetric total synthesis of cylindrocyclophanes A and F through cyclodimerization and a Ramberg-Bäcklund reaction Angewandte Chemie-International Edition 2010 49:5875-5878 DOI:10.1002/anie.201003500 PMID:20623817 PMCID:PMC3014728
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Nicolaou, K. C., Sanchini, S., Wu, T. R., Sarlah, D. Total synthesis and structural revision of biyouyanagin B Chemistry-a European Journal 2010 16:7678-7682 DOI:10.1002/chem.201001474 PMID:20572192 PMCID:PMC3023179
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Nicolaou, K. C., Reingruber, R., Sarlah, D., Brase, S. Enantioselective intramolecular Friedel−Crafts-type α-arylation of aldehydes Journal of the American Chemical Society 2009 131:2086-2087 DOI:10.1021/ja809405c PMID:19173649
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Nicolaou, K. C.*, Sarlah, D.*, Wu, T. R., Zhan, W. Q. Total synthesis of hirsutellone B Angewandte Chemie-International Edition 2009 48:6870-6874 DOI:10.1002/anie.200903382 PMID:19685548 PMCID:PMC2772144 (* = equal contribution)
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Nicolaou, K. C., Wu, T. R., Sarlah, D., Shaw, D. M., Rowcliffe, E., Burton, D. R. Total synthesis, revised structure, and biological evaluation of biyouyanagin A and analogues thereof Journal of the American Chemical Society 2008 130:11114-11121 DOI:10.1021/ja802805c PMID:18646750 PMCID:PMC2614900
- Dai, M., Sarlah, D., Yu, M., Danishefsky, S. J., Jones, G. O., Houk, K. N. Highly selective Diels-Alder reactions of directly connected enyne dienophiles Journal of the American Chemical Society 2007 129:645-657 DOI:10.1021/ja065762u PMID:17227028
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Nicolaou, K. C.*, Sarlah, D.*, Shaw, D. M. Total synthesis and revised structure of biyouyanagin A Angewandte Chemie-International Edition 2007 46:4708-4711 DOI:10.1002/anie.200701552 PMID:17523208 (* = equal contribution)
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Nicolaou, K. C., Pihko, P. M., Bernal, F., Frederick, M. O., Qian, W. Y., Uesaka, N., Diedrichs, N., Hinrichs, J., Koftis, T. V., Loizidou, E., Petrovic, G., Rodriquez, M., et al. Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure Journal of the American Chemical Society 2006 128:2244-2257 DOI:10.1021/ja0547477 PMID:16478178
- Zorko, M., Majerle, A., Sarlah, D., Keber, M. M., Mohar, B., Jerala, R. Combination of antimicrobial and endotoxin-neutralizing activities of novel oleoylamines Antimicrobial Agents and Chemotherapy 2005 49:2307-2313 DOI:10.1128/;aac.49.6.2307-2313.2005 PMID:15917526 PMCID:PMC1140490
- Nicolaou, K. C., Bulger, P. G., Sarlah, D. Metathesis reactions in total synthesis Angewandte Chemie-International Edition 2005 44:4490-4527 DOI:10.1002/anie.200500369 PMID:16003791
- Nicolaou, K. C., Bulger, P. G., Sarlah, D. Palladium-catalyzed cross-coupling reactions in total synthesis Angewandte Chemie-International Edition 2005 44:4442-4489 DOI:10.1002/anie.200500368 PMID:15991198