recent publications
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academic article
- Bell, E. W., Zheng, E. J., Ryno, L. M. Identification of inhibitors of the E. coli chaperone SurA using in silico and in vitro techniques Bioorganic & Medicinal Chemistry Letters 2018 28:3540-3548 DOI:10.1016/j.bmcl.2018.09.034 PMID:30301675
- Ryno, L. M., Cottine, C. Biological impact and ethical implications of pesticide use: a short module for upper-division-undergraduate biochemistry courses Journal of Chemical Education 2018 95:1771-1777 DOI:10.1021/acs.jchemed.8b00379
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Genereux, J. C., Qu, S., Zhou, M., Ryno, L. M., Wang, S., Shoulders, M. D., Kaufman, R. J., Lasmezas, C. I., Kelly, J. W., Wiseman, R. L.
Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis
EMBO Journal
2015
34:4-19
DOI:10.15252/embj.201488896
PMID:25361606
PMCID:PMC4291477
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Cooley, C. B., Ryno, L. M., Plate, L., Morgan, G. J., Hulleman, J. D., Kelly, J. W., Wiseman, R. L.
Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain
Proceedings of the National Academy of Sciences of the United States of America
2014
111:13046-13051
DOI:10.1073/pnas.1406050111
PMID:25157167
PMCID:PMC4246986
- Ryno, L. M., Reese, C., Tolan, M., O'Brien, J., Short, G., Sorriano, G., Nettleton, J., Fulton, K., Iovine, P. M. Amphiphilic graft copolymers from end-functionalized starches: synthesis, characterization, thin film preparation, and small molecule loading Biomacromolecules 2014 15:2944-2951 DOI:10.1021/bm500572v PMID:25033423
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Ryno, L. M., Genereux, J. C., Naito, T., Morimoto, R. I., Powers, E. T., Shoulders, M. D., Wiseman, R. L.
Characterizing the altered cellular proteome induced by the stress-independent activation of heat shock factor 1
ACS Chemical Biology
2014
9:1273-1283
DOI:10.1021/cb500062n
PMID:24689980
PMCID:PMC4076015
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Wang, X., Cattaneo, F., Ryno, L., Hulleman, J., Reixach, N., Buxbaum, J. N.
The systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice
Journal of Neuroscience
2014
34:7253-7265
DOI:10.1523/jneurosci.4936-13.2014
PMID:24849358
PMCID:PMC4028500
- Ryno, L. M., Levine, Y., Iovine, P. M. Synthesis, characterization, and comparative analysis of amylose-guest complexes prepared by microwave irradiation Carbohydrate Research 2014 383:82-88 DOI:10.1016/j.carres.2013.11.010 PMID:24333898
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Shoulders, M. D., Ryno, L. M., Cooley, C. B., Kelly, J. W., Wiseman, R. L.
Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells
Journal of the American Chemical Society
2013
135:8129-8132
DOI:10.1021/ja402756p
PMID:23682758
PMCID:PMC23682758
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Ryno, L. M., Wiseman, R. L., Kelly, J. W.
Targeting unfolded protein response signaling pathways to ameliorate protein misfolding diseases
Current Opinion in Chemical Biology
2013
17:346-352
DOI:10.1016/j.cbpa.2013.04.009
PMID:23647985
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Shoulders, M. D., Ryno, L. M., Genereux, J. C., Moresco, J. J., Tu, P. G., Wu, C., Yates, J. R., 3rd, Su, A. I., Kelly, J. W., Wiseman, R. L.
Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments
Cell Reports
2013
3:1279-1292
DOI:10.1016/j.celrep.2013.03.024
PMID:23583182
PMCID:PMC3754422
- Ramalingam, V., Kwee, S. K., Ryno, L. M., Urbach, A. R. A cucurbit[8]uril sponge Organic & Biomolecular Chemistry 2012 10:8587-8589 DOI:10.1039/c2ob26774h PMID:23042328
- Chinai, J. M., Taylor, A. B., Ryno, L. M., Hargreaves, N. D., Morris, C. A., Hart, P. J., Urbach, A. R. Molecular recognition of insulin by a synthetic receptor Journal of the American Chemical Society 2011 133:8810-8813 DOI:10.1021/ja201581x PMID:21473587 PMCID:PMC3110995