Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form
Rosenblum, Jonathan
Display my h-index
Publications in VIVO
 
    Export Publications Table
co-author
Co-author Network
map of science
Map of Science
Biosketch in .docx format  Create Biosketch

Rosenblum, Jonathan

Graduate Student
share the uri qr icon Close

Positions

  • 2013 - Senior Director, Research, ActivX Biosciences

Websites

  • Doctoral Dissertation
  • Publications
  • Background
  • Contact
  • View All
scroll to property group menus

Publications

recent publications
  • All Publications
  • PubMed Display for Export
  • Publications without PubMed PMIDs

  • academic article

    • Lin, E. C. K., Amantea, C. M., Nomanbhoy, T. K., Weissig, H., Ishiyama, J., Hu, Y., Sidique, S., Li, B., Kozarich, J. W., Rosenblum, J. S. ERK5 kinase activity is dispensable for cellular immune response and proliferation Proceedings of the National Academy of Sciences of the United States of America  2016 113:11865-11870  DOI:10.1073/pnas.1609019113  PMID:27679845  PMCID:PMC5081620
    • Nomanbhoy, T. K., Sharma, G., Brown, H., Wu, J., Aban, A., Vogeti, S., Alemayehu, S., Sykes, M., Rosenblum, J. S., Kozarich, J. W. Chemoproteomic evaluation of target engagement by the cyclin-dependent kinase 4 and 6 inhibitor palbociclib correlates with cancer cell response Biochemistry  2016 55:5434-5441  DOI:10.1021/acs.biochem.6b00629  PMID:27571378
    • Chillappagari, S., Muller, C., Mahavadi, P., Guenther, A., Nahrlich, L., Rosenblum, J., Rubin, B. K., Henke, M. O. A small molecule neutrophil elastase inhibitor, KRP-109, inhibits cystic fibrosis mucin degradation Journal of Cystic Fibrosis  2016 15:325-331  DOI:10.1016/j.jcf.2015.10.008  PMID:26526358
    • Okerberg, E. S., Hainley, A., Brown, H., Aban, A., Alemayehu, S., Shih, A., Wu, J., Patricelli, M. P., Kozarich, J. W., Nomanbhoy, T., Rosenblum, J. S. Identification of a tumor specific, active-site mutation in casein kinase 1α by chemical proteomics PLoS One  2016 11  DOI:10.1371/journal.pone.0152934  PMID:27031502
    • Nordin, B. E., Liu, Y., Aban, A., Brown, H. E., Wu, J., Hainley, A. K., Rosenblum, J. S., Nomanbhoy, T. K., Kozarich, J. W. ATP acyl phosphate reactivity reveals native conformations of Hsp90 para logs and inhibitor target engagement Biochemistry  2015 54:3024-3036  DOI:10.1021/acs.biochem.5b00148
    • Okerberg, E. S., Brown, H. E., Minimo, L., Alemayehu, S., Rosenblum, J., Patricelli, M., Nomanbhoy, T., Kozarich, J. W. Monitoring native p38α:MK2/3 complexes via trans delivery of an ATP acyl phosphate probe Journal of the American Chemical Society  2014 136:4664-4669  DOI:10.1021/ja4129907  PMID:24601623
    • Harstad, E. B., Rosenblum, J. S., Gorrell, M. D., Achanzar, W. E., Minimo, L., Wu, J., Rosini-Marthaler, L., Gullo, R., Ordway, N. D., Kirby, M. S., Chadwick, K. D., Cosma, G. N., et al. DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues Regulatory Peptides  2013 186:26-35  DOI:10.1016/j.regpep.2013.07.003  PMID:23850796
    • Rosenblum, J. S., Nomanbhoy, T. K., Kozarich, J. W. Functional interrogation of kinases and other nucleotide-binding proteins FEBS Letters  2013 587:1870-1877  DOI:10.1016/j.febslet.2013.05.008  PMID:23684650
    • Shreder, K. R., Lin, E. C. K., Wu, J., Cajica, J., Amantea, C. M., Hu, Y., Okerberg, E., Brown, H. E., Pham, L. M., Chung, D. M., Fraser, A. S., McGee, E., et al. Synthesis and structure-activity relationship of (1-halo-2-naphthyl) carbamate-based inhibitors of KIAA1363 (NCEH1/AADACL1) Bioorganic & Medicinal Chemistry Letters  2012 22:5748-5751  DOI:10.1016/j.bmcl.2012.05.102  PMID:22877630
    • Cociorva, O. M., Li, B., Nomanbhoy, T., Li, Q., Nakamura, A., Nakamura, K., Nomura, M., Okada, K., Seto, S., Yumoto, K., Liyanage, M., Zhang, M. C., et al. Synthesis and structure-activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3 beta Bioorganic & Medicinal Chemistry Letters  2011 21:5948-5951  DOI:10.1016/j.bmcl.2011.07.073  PMID:21873061
    • Chaves, S. R., Rosenblum, J. S. Efficient nuclear transport of structurally disturbed cargo: mutations in a cargo protein switch its cognate karyopherin PLoS One  2011 6  DOI:10.1371/journal.pone.0016846  PMID:21347375  PMCID:PMC3036716
    • Miyazaki, M., Rosenblum, J. S., Kasahara, Y., Nakagawa, I., Patricelli, M. P. Determination of enzymatic source of alanine aminotransferase activity in serum from dogs with liver injury Journal of Pharmacological and Toxicological Methods  2009 60:307-315  DOI:10.1016/j.vascn.2009.09.001  PMID:19748590
    • Liu, Y., Jiang, N., Wu, J., Dai, W., Rosenblum, J. S. Polo-like kinases inhibited by Wortmannin. Labeling site and downstream effects Journal of Biological Chemistry  2007 282:2505-2511  DOI:10.1074/jbc.M609603200  PMID:17135248
    • Danilova, O., Li, B., Szardenings, A. K., Huber, B. T., Rosenblum, J. S. Synthesis and activity of a potent, specific azabicyclo[3.3.0]-octane-based DPP II inhibitor Bioorganic & Medicinal Chemistry Letters  2007 17:507-510  DOI:10.1016/j.bmcl.2006.10.012  PMID:17055271  PMCID:PMC1828633
    • Shreder, K. R., Wong, M. S., Corral, S., Yu, Z., Winn, D. T., Wu, M., Hu, Y., Nomanbhoy, T., Alemayehu, S., Fuller, S. R., Rosenblum, J. S., Kozarich, J. W. Boro-norleucine as a P1 residue for the design of selective and potent DPP7 inhibitors Bioorganic & Medicinal Chemistry Letters  2005 15:4256-4260  DOI:10.1016/j.bmcl.2005.06.076  PMID:16084722
    • Hu, Y., Ma, L., Wu, M., Wong, M. S., Li, B., Corral, S., Yu, Z., Nomanbhoy, T., Alemayehu, S., Fuller, S. R., Rosenblum, J. S., Rozenkrants, N., et al. Synthesis and structure-activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7 Bioorganic & Medicinal Chemistry Letters  2005 15:4239-4242  DOI:10.1016/j.bmcl.2005.06.075  PMID:16085416
    • Liu, Y., Shreder, K. R., Gai, W., Corral, S., Ferris, D. K., Rosenblum, J. S. Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase Chemistry & Biology  2005 12:99-107  DOI:10.1016/j.chembiol.2004.11.009  PMID:15664519
    • Baxter, S. M., Rosenblum, J. S., Knutson, S., Nelson, M. R., Montimurro, J. S., Di Gennaro, J. A., Speir, J. A., Burbaum, J. J., Fetrow, J. S. Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast Molecular & Cellular Proteomics  2004 3:209-225  DOI:10.1074/mcp.M300082-MCP200  PMID:14645503
    • Rosenblum, J. S., Kozarich, J. W. Proyl peptidases: a serine protease subfamily with high potential for drug discovery Current Opinion in Chemical Biology  2003 7:496-504  DOI:10.1016/s1367-5931(03)00084-x  PMID:12941425
    • Nomanbhoy, T. K., Rosenblum, J., Aban, A., Burbaum, J. J. Inhibitor focusing: direct selection of drug targets from proteomes using activity-based probes Assay and Drug Development Technologies  2003 1:137-146  DOI:10.1089/154065803321537854  PMID:15090140
    • Rosenblum, J. S., Blobel, G. Autoproteolysis in nucleoporin biogenesis Proceedings of the National Academy of Sciences of the United States of America  1999 96:11370-11375  DOI:10.1073/pnas.96.20.11370  PMID:10500183  PMCID:PMC18040
    • Pemberton, L. F., Rosenblum, J. S., Blobel, G. Nuclear import of the TATA-binding protein: mediation by the karyopherin Kap114p and a possible mechanism for intranuclear targeting Journal of Cell Biology  1999 145:1407-1417  PMID:10385521  PMCID:PMC2133169
    • Albertini, M., Pemberton, L. F., Rosenblum, J. S., Blobel, G. A novel nuclear import pathway for the transcription factor TFIIS Journal of Cell Biology  1998 143:1447-1455  PMID:9852143  PMCID:PMC2132971
    • Rosenblum, J. S., Pemberton, L. F., Bonifaci, N., Blobel, G. Nuclear import and the evolution of a multifunctional RNA-binding protein Journal of Cell Biology  1998 143:887-899  PMID:9817748  PMCID:PMC2132966
    • Pemberton, L. F., Blobel, G., Rosenblum, J. S. Transport routes through the nuclear pore complex Current Opinion in Cell Biology  1998 10:392-399  DOI:10.1016/S0955-0674(98)80016-1  PMID:9640541
    • Pemberton, L. F., Rosenblum, J. S., Blobel, G. A distinct and parallel pathway for the nuclear import of an mRNA-binding protein Journal of Cell Biology  1997 139:1645-1653  PMID:9412460  PMCID:PMC2132632
    • Rosenblum, J. S., Pemberton, L. F., Blobel, G. A nuclear import pathway for a protein involved in tRNA maturation Journal of Cell Biology  1997 139:1655-1661  PMID:9412461  PMCID:PMC2132634
    • degree-related publication Rosenblum, J. S., Gilula, N. B., Lerner, R. A. On signal sequence polymorphisms and diseases of distribution Proceedings of the National Academy of Sciences of the United States of America  1996 93:4471-4473  DOI:10.1073/pnas.93.9.4471  PMID:8633092
    • degree-related publication Rosenblum, J. S., Lo, L. C., Li, T. Y., Janda, K. D., Lerner, R. A. Antibody-catalyzed phosphate triester hydrolysis Angewandte Chemie-International Edition  1995 34:2275-2277  DOI:10.1002/anie.199522751
    • degree-related publication Barbas, C. F., Rosenblum, J. S., Lerner, R. A. Direct selection of antibodies that coordinate metals from semisynthetic combinatorial libraries Proceedings of the National Academy of Sciences of the United States of America  1993 90:6385-6389  PMID:8341642  PMCID:PMC46936
scroll to property group menus

Background

education and training

  • Ph.D. in Chemistry, Scripps Research 1991 - 1996
  • B.A. in Chemistry, University of Pennsylvania , with Honors 1987 - 1991

advisee of

  • graduate advising relationship

    • Lerner, Richard, Ph.D.  candidacy, 1992 - 1996
scroll to property group menus

Contact

full name

  • Jonathan S Rosenblum

geographic location

  • Scripps California 

©2021 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support