academic article

• Schuepbach, R. A., Madon, J., Ender, M., Galli, P., Riewald, M. Protease-activated receptor-1 cleaved at r46 mediates cytoprotective effects Journal of Thrombosis and Haemostasis  2012 10:1675-1684  DOI:10.1111/j.1538-7836.2012.04825.x  PMID:22712885  PMCID:PMC3419798
• Schuepbach, R. A., Velez, K., Riewald, M. Activated protein c up-regulates procoagulant tissue factor activity on endothelial cells by shedding the tfpi kunitz 1 domain Blood  2011 117:6338-6346  DOI:10.1182/blood-2010-10-316257  PMID:21474669  PMCID:PMC3122952
• Schuepbach, R. A., Riewald, M. Coagulation factor xa cleaves protease-activated receptor-1 and mediates signaling dependent on binding to the endothelial protein c receptor Journal of Thrombosis and Haemostasis  2010 8:379-388  DOI:10.1111/j.1538-7836.2009.03682.x  PMID:19895674  PMCID:PMC3103137
• Mosnier, L. O., Zampolli, A., Kerschen, E. J., Schuepbach, R. A., Banerjee, Y., Fernandez, J. A., Yang, X. V., Riewald, M., Weiler, H., Ruggeri, Z. M., Griffin, J. H. Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant Blood  2009 113:5970-5978  DOI:10.1182/blood-2008-10-183327  PMID:19244160  PMCID:PMC2700330
• Schuepbach, R. A., Feistritzer, C., Fernandez, J. A., Griffin, J. H., Riewald, M. Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1 Thrombosis and Haemostasis  2009 101:724-733  DOI:10.1160/th08-10-0632  PMID:19350118  PMCID:PMC2680237
• Schuepbach, R. A., Feistritzer, C., Brass, L. F., Riewald, M. Activated protein c-cleaved protease activated receptor-1 is retained on the endothelial cell surface even in the presence of thrombin Blood  2008 111:2667-2673  DOI:10.1182/blood-2007-09-113076  PMID:18089851  PMCID:PMC2254534
• Feistritzer, C., Mosheimer, B. A., Sturn, D. H., Riewald, M., Patsch, J. R., Wiedermann, C. J. Endothelial protein c receptor-dependent inhibition of migration of human lymphocytes by protein c involves epidermal growth factor receptor Journal of Immunology  2006 176:1019-1025  PMID:16393989
• Feistritzer, C., Schuepbach, R. A., Mosnier, L. O., Bush, L. A., Di Cera, E., Griffin, J. H., Riewald, M. Protective signaling by activated protein C is mechanistically linked to protein C activation on endothelial cells Journal of Biological Chemistry  2006 281:20077-20084  DOI:10.1074/jbc.M600506200  PMID:16709569
• Feistritzer, C., Riewald, M. Endothelial barrier protection by activated protein c through par1-dependent sphingosine 1-phosphate receptor-1 crossactivation Blood  2005 105:3178-3184  DOI:10.1182/blood-2004-10-3985  PMID:15626732
• Riewald, M., Ruf, W. Protease-activated receptor-1 signaling by activated protein c in cytokine-perturbed endothelial cells is distinct from thrombin signaling Journal of Biological Chemistry  2005 280:19808-19814  DOI:10.1074/jbc.M500747200  PMID:15769747
• Feistritzer, C., Lenta, R., Riewald, M. Protease-activated receptors-1 and-2 can mediate endothelial barrier protection: Role in factor xa signaling Journal of Thrombosis and Haemostasis  2005 3:2798-2805  DOI:10.1111/j.1538-7836.2005.01610.x  PMID:16359518
• Feistritzer, C., Mosheimer, B. A., Kaneider, N. C., Riewald, M., Patsch, J. R., Wiedermann, C. J. Thrombin affects eosinophil migration via protease-activated receptor-1 International Archives of Allergy and Immunology  2004 135:12-16  DOI:10.1159/000080037  PMID:15286440
• Riewald, M., Petrovan, R. J., Donner, A., Ruf, W. Activated protein c signals through the thrombin receptor par1 in endothelial cells Journal of Endotoxin Research  2003 9:317-321  DOI:10.1179/096805103225002584  PMID:14577849
• Riewald, M., Ruf, W. Proteinase-activated receptor activation by coagulation proteinases Drug Development Research  2003 59:400-407  DOI:10.1002/ddr.10310
• Riewald, M., Ruf, W. Science review: Role of coagulation protease cascades in sepsis Critical Care  2003 7:123-129  DOI:10.1186/cc1825  PMID:12720558  PMCID:PMC270604
• Ruf, W., Dorfleutner, A., Riewald, M. Specificity of coagulation factor signaling Journal of Thrombosis and Haemostasis  2003 1:1495-1503  DOI:10.1046/j.1538-7836.2003.00300.x  PMID:12871285
• Ruf, W., Riewald, M. Tissue factor-dependent coagulation protease signaling in acute lung injury Critical Care Medicine  2003 31:S231-S237  DOI:10.1097/01.ccm.0000057848.27456.04  PMID:12682445
• Riewald, M., Petrovan, R. J., Donner, A., Mueller, B. M., Ruf, W. Activation of endothelial cell protease activated receptor 1 by the protein c pathway Science  2002 296:1880-1882  DOI:10.1126/science.1071699  PMID:12052963
• Riewald, M., Ruf, W. Orchestration of coagulation protease signaling by tissue factor Trends in Cardiovascular Medicine  2002 12:149-154  DOI:10.1016/s1050-1738(02)00153-6  PMID:12069753
• Riewald, M., Kravchenko, V. V., Petrovan, R. J., O'Brien, P. J., Brass, L. F., Ulevitch, R. J., Ruf, W. Gene induction by coagulation factor Xa is mediated by activation of protease-activated receptor 1 Blood  2001 97:3109-3116  DOI:10.1182/blood.V97.10.3109  PMID:11342437
• Riewald, M., Ruf, W. Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor Proceedings of the National Academy of Sciences of the United States of America  2001 98:7742-7747  DOI:10.1073/pnas.141126698  PMID:11438726  PMCID:PMC35412
• Ruf, W., Fischer, E. G., Huang, H. Y., Miyagi, Y., Ott, I., Riewald, M., Mueller, B. M. Diverse functions of protease receptor tissue factor in inflammation and metastasis Immunologic Research  2000 21:289-292  DOI:10.1385/ir:21:2-3:289  PMID:10852129
• Fischer, E. G., Riewald, M., Huang, H. Y., Miyagi, Y., Kubota, Y., Mueller, B. M., Ruf, W. Tumor cell adhesion and migration supported by interaction of a receptor-protease complex with its inhibitor Journal of Clinical Investigation  1999 104:1213-1221  DOI:10.1172/jci7750  PMID:10545520
• Riewald, M., Chuang, T., Neubauer, A., Riess, H., Schleef, R. R. Expression of bomapin, a novel human serpin, in normal/malignant hematopoiesis and in the monocytic cell lines thp-1 and aml-193 Blood  1998 91:1256-1262  PMID:9454755
• Riewald, M., Riess, H. Treatment options for clinically recognized disseminated intravascular coagulation Seminars in Thrombosis and Hemostasis  1998 24:53-59  DOI:10.1055/s-2007-995823  PMID:9515780
• Weisbach, V., Putzo, A., Zingsem, J., Riewald, M., Zimmermann, R., Eckstein, R., Riess, H. Leukocyte depletion and storage of single-donor platelet concentrates Vox Sanguinis  1997 72:20-25  DOI:10.1046/j.1423-0410.1997.00020.x  PMID:9031496
• Riewald, M., Schleef, R. R. Human cytoplasmic antiproteinase neutralizes rapidly and efficiently chymotrypsin and trypsin-like proteases utilizing distinct reactive site residues Journal of Biological Chemistry  1996 271:14526-14532  PMID:8662739
• Riewald, M., Morgenstern, K. A., Schleef, R. R. Identification and characterization of the cytoplasmic antiproteinase (cap) in human platelets - evidence for the interaction of cap with endogenous platelet proteins Journal of Biological Chemistry  1996 271:7160-7167  PMID:8636153
• Riewald, M., Schleef, R. R. Molecular-cloning of bomapin (protease-inhibitor-10), a novel human serpin that is expressed specifically in the bone-marrow Journal of Biological Chemistry  1995 270:26754-26757  PMID:7592909
• Riess, H., Riewald, M. The clinical impact of platelet-function testing Thrombosis Research  1994 74:S69-S78  PMID:8073403
• Himmelreich, G., Riewald, M., Rosch, R., Blumhard, G., Neuhaus, P., Roissant, R., Riess, H. Thrombomodulin - a marker for endothelial damage during orthotopic liver-transplantation American Journal of Hematology  1994 47:1-5  DOI:10.1002/ajh.2830470102  PMID:8042609
• Schadendorf, D., Algermissen, B., Hamann, K., Riewald, M., Nurnberger, F., Czarnetzki, B. M. Acute monoblastic leukemia with skin nodules in an adult Journal of the American Academy of Dermatology  1993 28:884-888  DOI:10.1016/0190-9622(93)70125-d  PMID:8491887
• Riewald, M., Himmelreich, G., Breindl, P., Neuhaus, P., Riess, H. Soluble thrombomodulin levels during orthotopic liver-transplantation Seminars in Thrombosis and Hemostasis  1993 19:246-249  DOI:10.1055/s-2007-994034  PMID:8395706
• Weisbach, V., Riess, H., Gindi, N., Zeiler, T., Riewald, M., Zingsem, J., Eckstein, R. Effects of leukocyte depletion on platelet concentrates using 2 different polyester filters Infusionstherapie und Transfusionsmedizin  1992 19:146-148  PMID:1498557
• Garibai, A. R., Rochlitz, C., Riewald, M., Oertel, J., Huhn, D. Treatment of neutropenia in feltys syndrome with granulocyte-macrophage colony-stimulating factor - hematological response accompanied by pulmonary complications with lethal outcome Annals of Hematology  1992 65:232-235  DOI:10.1007/bf01703951  PMID:1457582