recent publications
-
academic article
- Thompson, A. J., Cao, L., Ma, Y., Wang, X., Diedrich, J. K., Kikuchi, C., Willis, S., Worth, C., McBride, R., Yates III, J. R., Paulson, J. C. Human Influenza Virus Hemagglutinins Contain Conserved Oligomannose N-Linked Glycans Allowing Potent Neutralization by Lectins Cell Host & Microbe 2020 27:725-735 DOI:10.1016/j.chom.2020.03.009 PMID:32298658 PMCID:PMC7158820
- Eggink, D., Spronken, M., van der Woude, R., Buzink, J., Broszeit, F., McBride, R., Pawestri, H. A., Setiawaty, V., Paulson, J. C., Boons, G. J., Fouchier, R. A. M., Russell, C. A., et al. Phenotypic Effects of Substitutions within the Receptor Binding Site of Highly Pathogenic Avian Influenza H5N1 Virus Observed during Human Infection Journal of Virology 2020 94 DOI:10.1128/jvi.00195-20 PMID:32321815 PMCID:PMC7307160
- Lee, S., Yang, Y. A., Milano, S. K., Nguyen, T., Ahn, C., Sim, J. H., Thompson, A. J., Hillpot, E. C., Yoo, G., Paulson, J. C., Song, J. Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence Cell Host & Microbe 2020 27:937-946 DOI:10.1016/j.chom.2020.04.005 PMID:32396840 PMCID:PMC7292776
- Duan, S., Paulson, J. C. Siglecs as Immune Cell Checkpoints in Disease Annual Review of Immunology 2020 38:365-395 DOI:10.1146/annurev-immunol-102419-035900 PMID:31986070
- Nycholat, C. M., Duan, S., Knuplez, E., Worth, C., Elich, M., Yao, A., O'Sullivan, J., McBride, R., Wei, Y., Fernandes, S. M., Zhu, Z., Schnaar, R. L., et al. A sulfonamide sialoside analogue for targeting siglec-8 and -F on immune cells Journal of the American Chemical Society 2019 141:14032-14037 DOI:10.1021/jacs.9b05769 PMID:31460762
- Narimatsu, Y., Joshi, H. J., Nason, R., Van Coillie, J., Karlsson, R., Sun, L., Ye, Z., Chen, Y. H., Schjoldager, K. T., Steentoft, C., Furukawa, S., Bensing, B. A., et al. An atlas of human glycosylation pathways enables display of the human glycome by gene engineered cells Molecular Cell 2019 75:394-407 DOI:10.1016/j.molcel.2019.05.017 PMID:31227230 PMCID:PMC6660356
- Duan, S., Koziol-White, C. J., Jester Jr., W. F., Nycholat, C. M., Macauley, M. S., Panettieri Jr., R. A., Paulson, J. C. CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen Journal of Clinical Investigation 2019 129:1387-1401 DOI:10.1172/jci125456 PMID:30645205 PMCID:PMC6391081
- Bednar, K. J., Nycholat, C. M., Rao, T. S., Paulson, J. C., Fung-Leung, W. P., Macauley, M. S. Exploiting CD22 to selectively tolerize autoantibody producing B-cells in rheumatoid arthritis ACS Chemical Biology 2019 14:644-654 DOI:10.1021/acschembio.8b01018 PMID:30835424
- Obadan, A. O., Santos, J., Ferreri, L., Thompson, A. J., Carnaccini, S., Geiger, G., Reiche, A. S. G., Rajao, D. S., Paulson, J. C., Perez, D. R. Flexibility in vitro of amino acid 226 in the receptor-binding site of an H9 subtype influenza A virus and its effect in vivo on virus replication, tropism, and transmission Journal of Virology 2019 93:e02011-18 DOI:10.1128/jvi.02011-18 PMID:30567980 PMCID:PMC6401463
- Santos, J. J. S., Abente, E. J., Obadan, A. O., Thompson, A. J., Ferreri, L., Geiger, G., Gonzalez-Reiche, A. S., Lewis, N. S., Burke, D. F., Rajao, D. S., Paulson, J. C., Vincent, A. L., et al. Plasticity of amino acid residue 145 near the receptor binding site of H3 swine influenza A viruses and Its impact on receptor binding and antibody recognition Journal of Virology 2019 93:e01413-18 DOI:10.1128/jvi.01413-18 PMID:30355680 PMCID:PMC6321904
- Wu, N. C., Lv, H., Thompson, A. J., Wu, D. C., Ng, W. W. S., Kadam, R. U., Lin, C. W., Nycholat, C. M., McBride, R., Liang, W., Paulson, J. C., Mok, C. K. P., et al. Preventing an antigenically disruptive mutation in egg-based H3N2 seasonal influenza vaccines by mutational incompatibility Cell Host & Microbe 2019 25:836-844 DOI:10.1016/j.chom.2019.04.013 PMID:31151913
- Bhattacherjee, A., Rodrigues, E., Jung, J., Luzentales-Simpson, M., Enterina, J. R., Galleguillos, D., St Laurent, C. D., Nakhaei-Nejad, M., Fuchsberger, F. F., Streith, L., Wang, Q., Kawasaki, N., et al. Repression of phagocytosis by human CD33 is not conserved with mouse CD33 Communications Biology 2019 2 DOI:10.1038/s42003-019-0698-6 PMID:31815204 PMCID:PMC6890642
- Zhu, X., Turner, H. L., Lang, S., McBride, R., Bangaru, S., Gilchuk, I. M., Yu, W., Paulson, J. C., Crowe, J. E., Ward, A. B., Wilson, I. A. Structural basis of protection against H7N9 influenza virus by human anti-N9 neuraminidase antibodies Cell Host & Microbe 2019 26:729-738 DOI:10.1016/j.chom.2019.10.002 PMID:31757767 PMCID:PMC6908751
- Neelamegham, S., Aoki-Kinoshita, K., Bolton, E., Frank, M., Lisacek, F., Lutteke, T., O'Boyle, N., Packer, N. H., Stanley, P., Toukach, P., Varki, A., Woods, R. J., et al. Updates to the Symbol Nomenclature for Glycans guidelines Glycobiology 2019 29:620-624 DOI:10.1093/glycob/cwz045 PMID:31184695
- Thompson, A. J., de Vries, R. P., Paulson, J. C. Virus recognition of glycan receptors Current Opinion in Virology 2019 34:117-129 DOI:10.1016/j.coviro.2019.01.004 PMID:30849709 PMCID:PMC6476673
- Wu, N. C., Thompson, A. J., Xie, J., Lin, C. W., Nycholat, C. M., Zhu, X., Lerner, R. A., Paulson, J. C., Wilson, I. A. A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site Nature Communications 2018 9 DOI:10.1038/s41467-018-03663-5 PMID:29593268 PMCID:PMC5871881
- de Toro, B. F., Peng, W. J., Thompson, A. J., Dominguez, G., Canada, F. J., Perez-Castells, J., Paulson, J. C., Jimenez-Barbero, J., Canales, A. Avenues to characterize the interactions of extended N-glycans with proteins by NMR spectroscopy: the influenza hemagglutinin case Angewandte Chemie-International Edition 2018 57:15051-15055 DOI:10.1002/anie.201807162 PMID:30238596 PMCID:PMC6282704
- Hatta, M., Zhong, G., Gao, Y., Nakajima, N., Fan, S., Chiba, S., Deering, K. M., Ito, M., Imai, M., Kiso, M., Nakatsu, S., Lopes, T. J., et al. Characterization of a feline influenza A(H7N2) virus Emerging Infectious Diseases 2018 24:75-86 DOI:10.3201/eid2401.171240 PMID:29260686 PMCID:PMC5749472
- Rantalainen, K., Berndsen, Z. T., Murrell, S., Cao, L., Omorodion, O., Torres, J. L., Wu, M., Umotoy, J., Copps, J., Poignard, P., Landais, E., Paulson, J. C., et al. Co-evolution of HIV envelope and apex-targeting neutralizing antibody lineage provides benchmarks for vaccine design Cell Reports 2018 23:3249-3261 DOI:10.1016/j.celrep.2018.05.046 PMID:29898396 PMCID:PMC6019700
- Cao, L. W., Pauthner, M., Andrabi, R., Rantalainen, K., Berndsen, Z., Diedrich, J. K., Menis, S., Sok, D., Bastidas, R., Park, S. K. R., Delahunty, C. M., He, L., et al. Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer Nature Communications 2018 9 DOI:10.1038/s41467-018-06121-4 PMID:30209313 PMCID:PMC6135743
- Imai, H., Dinis, J. M., Zhong, G., Moncla, L. H., Lopes, T. J. S., McBride, R., Thompson, A. J., Peng, W., Le, M. T. Q., Hanson, A., Lauck, M., Sakai-Tagawa, Y., et al. Diversity of influenza A(H5N1) viruses in infected humans, Northern Vietnam, 2004-2010 Emerging Infectious Diseases 2018 24:1228-1238 DOI:10.3201/eid2407.171441 PMID:29912683
- Peng, W., Bouwman, K. M., McBride, R., Grant, O. C., Woods, R. J., Verheije, M. H., Paulson, J. C., de Vries, R. P. Enhanced human-type receptor binding by ferret-transmissible H5N1 with a K193T mutation Journal of Virology 2018 92:e02016-17 DOI:10.1128/jvi.02016-17 PMID:29491160 PMCID:PMC5923085
- Cao, L., Diedrich, J. K., Ma, Y., Wang, N., Pauthner, M., Park, S. K. R., Delahunty, C. M., McLellan, J. S., Burton, D. R., Yates III, J. R., Paulson, J. C. Global site-specific analysis of glycoprotein N-glycan processing Nature Protocols 2018 13:1196-1212 DOI:10.1038/nprot.2018.024 PMID:29725121 PMCID:PMC5941933
- Yang, Y. A., Lee, S., Zhao, J., Thompson, A. J., McBride, R., Tsogtbaatar, B., Paulson, J. C., Nussinov, R., Deng, L., Song, J. In vivo tropism of Salmonella Typhi toxin to cells expressing a multiantennal glycan receptor Nature Microbiology 2018 3:155-163 DOI:10.1038/s41564-017-0076-4 PMID:29203881
- Guo, H., Rabouw, H., Slomp, A., Dai, M., van der Vegt, F., van Lent, J. W. M., McBride, R., Paulson, J. C., de Groot, R. J., van Kuppeveld, F. J. M., de Vries, E., de Haan, C. A. M. Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces PLoS Pathogens 2018 14 DOI:10.1371/journal.ppat.1007233 PMID:30102740 PMCID:PMC6107293
- Sun, Y., Hong, S., Xie, R., Huang, R., Lei, R., Cheng, B., Sun, D. E., Du, Y., Nycholat, C. M., Paulson, J. C., Chen, X. Mechanistic investigation and multiplexing of liposome-assisted metabolic glycan labeling Journal of the American Chemical Society 2018 140:3592-3602 DOI:10.1021/jacs.7b10990 PMID:29446631
- Han, K. H., Arlian, B. M., Macauley, M. S., Paulson, J. C., Lerner, R. A. Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid β Proceedings of the National Academy of Sciences of the United States of America 2018 115:E372-E381 DOI:10.1073/pnas.1719259115 PMID:29295920 PMCID:PMC5777004
- Spiller, F., Nycholat, C. M., Kikuchi, C., Paulson, J. C., Macauley, M. S. Murine red blood cells lack ligands for B cell Siglecs, allowing strong activation by erythrocyte surface antigens Journal of Immunology 2018 200:949-956 DOI:10.4049/jimmunol.1701257 PMID:29288201 PMCID:PMC5780208
- Gao, Z., Thompson, A. J., Paulson, J. C., Withers, S. G. Proximity Ligation-Based Fluorogenic Imaging Agents for Neuraminidases Angewandte Chemie-International Edition 2018 57:13538-13541 DOI:10.1002/anie.201808196 PMID:30216626
- Gonzalez-Gil, A., Porell, R. N., Fernandes, S. M., Wei, Y. D., Yu, H. F., Carroll, D. J., McBride, R., Paulson, J. C., Tiemeyer, M., Aoki, K., Bochner, B. S., Schnaar, R. L. Sialylated keratan sulfate proteoglycans are Siglec-8 ligands in human airways Glycobiology 2018 28:786-801 DOI:10.1093/glycob/cwy057 PMID:29924315 PMCID:PMC6142871
- Havenar-Daughton, C., Sarkar, A., Kulp, D. W., Toy, L., Hu, X., Deresa, I., Kalyuzhniy, O., Kaushik, K., Upadhyay, A. A., Menis, S., Landais, E., Cao, L., et al. The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen Science Translational Medicine 2018 10 DOI:10.1126/scitranslmed.aat0381 PMID:29973404
- Lee, J. H., Andrabi, R., Su, C. Y., Yasmeen, A., Julien, J. P., Kong, L., Wu, N. C., McBride, R., Sok, D., Pauthner, M., Cottrell, C. A., Nieusma, T., et al. A broadly neutralizing antibody targets the dynamic HIV envelope trimer apex via a long, rigidified, and anionic β-hairpin structure Immunity 2017 46:690-702 DOI:10.1016/j.immuni.2017.03.017 PMID:28423342 PMCID:PMC5400778
- Imai, M., Watanabe, T., Kiso, M., Nakajima, N., Yamayoshi, S., Iwatsuki-Horimoto, K., Hatta, M., Yamada, S., Ito, M., Sakai-Tagawa, Y., Shirakura, M., Takashita, E., et al. A highly pathogenic avian H7N9 influenza virus isolated from a human Is lethal in some ferrets infected via respiratory droplets Cell Host & Microbe 2017 22:615-626 DOI:10.1016/j.chom.2017.09.008 PMID:29056430
- de Vries, R. P., Tzarum, N., Peng, W., Thompson, A. J., Wickramasinghe, I. N. A., de la Pena, A. T. T., van Breemen, M. J., Bouwman, K. M., Zhu, X., McBride, R., Yu, W., Sanders, R. W., et al. A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors EMBO Molecular Medicine 2017 9:1314-1325 DOI:10.15252/emmm.201707726 PMID:28694323 PMCID:PMC5582370
- Wu, N. C., Zost, S. J., Thompson, A. J., Oyen, D., Nycholat, C. M., McBride, R., Paulson, J. C., Hensley, S. E., Wilson, I. A. A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine PLoS Pathogens 2017 13 DOI:10.1371/journal.ppat.1006682 PMID:29059230 PMCID:PMC5667890
- Taubenschmid, J., Stadlmann, J., Jost, M., Klokk, T. I., Rillahan, C. D., Leibbrandt, A., Mechtler, K., Paulson, J. C., Jude, J., Zuber, J., Sandvig, K., Elling, U., et al. A vital sugar code for ricin toxicity Cell Research 2017 27:1351-1364 DOI:10.1038/cr.2017.116 PMID:28925387 PMCID:PMC5674155
- Hanske, J., Schulze, J., Aretz, J., McBride, R., Loll, B., Schmidt, H., Knirel, Y., Rabsch, W., Wahl, M. C., Paulson, J. C., Rademacher, C. Bacterial polysaccharide specificity of the pattern recognition receptor langerin is highly species- dependent Journal of Biological Chemistry 2017 292:862-871 DOI:10.1074/jbc.M116.751750 PMID:27903635 PMCID:PMC5247659
- Peng, W. J., Paulson, J. C. CD22 ligands on a natural N-glycan scaffold efficiently deliver toxins to B-lymphoma cells Journal of the American Chemical Society 2017 139:12450-12458 DOI:10.1021/jacs.7b03208 PMID:28829594
- Wu, N. C., Xie, J., Zheng, T., Nycholat, C. M., Grande, G., Paulson, J. C., Lerner, R. A., Wilson, I. A. Diversity of functionally permissive sequences in the receptor-binding site of influenza hemagglutinin Cell Host & Microbe 2017 21:742-753 DOI:10.1016/j.chom.2017.05.011 PMID:28618270
- Pang, L., Macauley, M. S., Arlian, B. M., Nycholat, C. M., Paulson, J. C. Encapsulating an immunosuppressant enhances tolerance induction by Siglec-engaging tolerogenic liposomes ChemBioChem 2017 18:1226-1233 DOI:10.1002/cbic.201600702 PMID:28231415 PMCID:PMC5496789
- Orgel, K. A., Duan, S., Wright, B. L., Maleki, S. J., Wolf, J. C., Vickery, B. P., Burks, A. W., Paulson, J. C., Kulis, M. D., Macauley, M. S. Exploiting CD22 on antigen-specific B cells to prevent allergy to the major peanut allergen Ara h 2 Journal of Allergy and Clinical Immunology 2017 139:366-369 DOI:10.1016/j.jaci.2016.06.053 PMID:27554819 PMCID:PMC5222808
- Cao, L., Diedrich, J. K., Kulp, D. W., Pauthner, M., He, L., Park, S. K. R., Sok, D., Su, C. Y., Delahunty, C. M., Menis, S., Andrabi, R., Guenaga, J., et al. Global site-specific N-glycosylation analysis of HIV envelope glycoprotein Nature Communications 2017 8 DOI:10.1038/ncomms14954 PMID:28348411
- Tiemeyer, M., Aoki, K., Paulson, J., Cummings, R. D., York, W. S., Karlsson, N. G., Lisacek, F., Packer, N. H., Campbell, M. P., Aoki, N. P., Fujita, A., Matsubara, M., et al. GlyTouCan: an accessible glycan structure repository Glycobiology 2017 27:915-919 DOI:10.1093/glycob/cwx066 PMID:28922742
- Guo, H., de Vries, E., McBride, R., Dekkers, J., Peng, W., Bouwman, K. M., Nycholat, C., Verheije, M. H., Paulson, J. C., van Kuppeveld, F. J. M., de Haan, C. A. M. Highly pathogenic influenza A(H5Nx) viruses with altered H5 receptor-binding specificity Emerging Infectious Diseases 2017 23:220-231 DOI:10.3201/eid2302.161072 PMID:27869615 PMCID:PMC5324792
- Bednar, K. J., Shanina, E., Ballet, R., Connors, E. P., Duan, S., Juan, J., Arlian, B. M., Kulis, M. D., Butcher, E. C., Fung-Leung, W. P., Rao, T. S., Paulson, J. C., et al. Human CD22 inhibits murine B cell receptor activation in a human CD22 transgenic mouse model Journal of Immunology 2017 199:3116-3128 DOI:10.4049/jimmunol.1700898 PMID:28972089 PMCID:PMC5679471
- Li, W., Hulswit, R. J. G., Widjaja, I., Raj, V. S., McBride, R., Peng, W., Widagdo, W., Tortorici, M. A., van Dieren, B., Lang, Y., van Lent, J. W. M., Paulson, J. C., et al. Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein Proceedings of the National Academy of Sciences of the United States of America 2017 114:E8508-E8517 DOI:10.1073/pnas.1712592114 PMID:28923942 PMCID:PMC5635925
- Dai, M., McBride, R., Dortmans, J.C., Peng, W., Bakkers, M. J., de Groot, R. J., van Kuppeveld, F. J., Paulson, J. C., de Vries, E., de Haan, C. A. Mutation of the second sialic acid-binding site, resulting in reduced neuraminidase activity, preceded the emergence of H7N9 influenza A virus Journal of Virology 2017 91:e00049-17 DOI:10.1128/jvi.00049-17 PMID:28202753 PMCID:PMC5391454
- Zanin, M., Kocer, Z. A., Poulson, R. L., Gabbard, J. D., Howerth, E. W., Jones, C. A., Friedman, K., Seiler, J., Danner, A., Kercher, L., McBride, R., Paulson, J. C., et al. Potential for low-pathogenic avian H7 influenza A viruses to replicate and cause disease in a mammalian model Journal of Virology 2017 91 DOI:10.1128/jvi.01934-16 PMID:27852855 PMCID:PMC5244340
- Peng, W., de Vries, R. P., Grant, O. C., Thompson, A. J., McBride, R., Tsogtbaatar, B., Lee, P. S., Razi, N., Wilson, I. A., Woods, R. J., Paulson, J. C. Recent H3N2 viruses have evolved specificity for extended, branched human-type receptors, conferring potential for increased avidity Cell Host & Microbe 2017 21:23-34 DOI:10.1016/j.chom.2016.11.004 PMID:28017661 PMCID:PMC5233592
- Polonskaya, Z., Deng, S., Sarkar, A., Kain, L., Comellas-Aragones, M., McKay, C. S., Kaczanowska, K., Holt, M., McBride, R., Palomo, V., Self, K. M., Taylor, S., et al. T cells control the generation of nanomolar-affinity anti-glycan antibodies Journal of Clinical Investigation 2017 127:1491-1504 DOI:10.1172/jci91192 PMID:28287405 PMCID:PMC5373877
- Tzarum, N., de Vries, R. P., Peng, W., Thompson, A. J., Bouwman, K. M., McBride, R., Yu, W., Zhu, X., Verheije, M. H., Paulson, J. C., Wilson, I. A. The 150-loop restricts the host specificity of human H10N8 influenza virus Cell Reports 2017 19:235-245 DOI:10.1016/j.celrep.2017.03.054 PMID:28402848 PMCID:PMC5452617
- Liu, Y., McBride, R., Stoll, M., Palma, A. S., Silva, L., Agravat, S., Aoki-Kinoshita, K. F., Campbell, M. P., Costello, C. E., Dell, A., Haslam, S. M., Karlsson, N. G., et al. The minimum information required for a glycomics experiment (MIRAGE) project: Improving the standards for reporting glycan microarray-based data Glycobiology 2017 27:280-284 DOI:10.1093/glycob/cww118 PMID:27993942
- de Vries, R. P., Peng, W., Grant, O. C., Thompson, A. J., Zhu, X., Bouwman, K. M., de la Pena, A. T. T., van Breemen, M. J., Wickramasinghe, I. N. A., de Haan, C. A. M., Yu, W., McBride, R., et al. Three mutations switch H7N9 influenza to human-type receptor specificity PLoS Pathogens 2017 13 DOI:10.1371/journal.ppat.1006390 PMID:28617868 PMCID:PMC5472306
- Tzarum, N., McBride, R., Nycholat, C. M., Peng, W., Paulson, J. C., Wilson, I. A. Unique structural features of influenza virus H15 hemagglutinin Journal of Virology 2017 91:e00046-17 DOI:10.1128/jvi.00046-17 PMID:28404848
- McBride, R., Paulson, J. C., de Vries, R. P. A miniaturized glycan microarray assay for assessing avidity and specificity of influenza A virus hemagglutinins Journal of Visualized Experiments : JoVE 2016 DOI:10.3791/53847 PMID:27284789 PMCID:PMC4927745
- Hiono, T., Okamatsu, M., Igarashi, M., McBride, R., de Vries, R. P., Peng, W., Paulson, J. C., Sakoda, Y., Kida, H. Amino acid residues at positions 222 and 227 of the hemagglutinin together with the neuraminidase determine binding of H5 avian influenza viruses to sialyl Lewis X Archives of Virology 2016 161:307-316 DOI:10.1007/s00705-015-2660-3 PMID:26542967 PMCID:PMC5030063
- Hanson, A., Imai, M., Hatta, M., McBride, R., Imai, H., Taft, A., Zhong, G., Watanabe, T., Suzuki, Y., Neumann, G., Paulson, J. C., Kawaoka, Y. Identification of stabilizing mutations in an H5 hemagglutinin influenza virus protein Journal of Virology 2016 90:2981-2992 DOI:10.1128/jvi.02790-15 PMID:26719265 PMCID:PMC4810667
- Gicheva, N., Macauley, M. S., Arlian, B. M., Paulson, J. C., Kawasaki, N. Siglec-F is a novel intestinal M cell marker Biochemical and Biophysical Research Communications 2016 479:1-4 DOI:10.1016/j.bbrc.2016.08.055 PMID:27524237 PMCID:PMC5045273
- Struwe, W. B., Agravat, S., Aoki-Kinoshita, K. F., Campbell, M. P., Costello, C. E., Dell, A., Feizi, T., Haslam, S. M., Karlsson, N. G., Khoo, K. H., Kolarich, D., Liu, Y., et al. The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets Glycobiology 2016 26:907-910 DOI:10.1093/glycob/cww082 PMID:27654115 PMCID:PMC5045532
- Sommer, R., Wagner, S., Varrot, A., Nycholat, C. M., Khaledi, A., Haussler, S., Paulson, J. C., Imberty, A., Titz, A. The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery Chemical Science 2016 7:4990-5001 DOI:10.1039/c6sc00696e
- Varki, A., Cummings, R. D., Aebi, M., Packer, N. H., Seeberger, P. H., Esko, J. D., Stanley, P., Hart, G., Darvill, A., Kinoshita, T., Prestegard, J. J., Schnaar, R. L., et al. Symbol nomenclature for graphical representations of glycans Glycobiology 2015 25:1323-1324 DOI:10.1093/glycob/cwv091 PMID:26543186 PMCID:PMC4643639
- Zhang, H., de Vries, R. P., Tzarum, N., Zhu, X., Yu, W., McBride, R., Paulson, J. C., Wilson, I. A. A human-infecting H10N8 influenza virus retains a strong preference for avian-type receptors Cell Host & Microbe 2015 17:377-384 DOI:10.1016/j.chom.2015.02.006 PMID:25766296 PMCID:PMC4359746
- Yoon, S. W., Chen, N., Ducatez, M. F., McBride, R., Barman, S., Fabrizio, T. P., Webster, R. G., Haliloglu, T., Paulson, J. C., Russell, C. J., Hertz, T., Ben-Tal, N., et al. Changes to the dynamic nature of hemagglutinin and the emergence of the 2009 pandemic H1N1 influenza virus Scientific Reports 2015 5:12828 DOI:10.1038/srep12828 PMID:26269288 PMCID:PMC4534793
- Zaraket, H., Baranovich, T., Kaplan, B. S., Carter, R., Song, M. S., Paulson, J. C., Rehg, J. E., Bahl, J., Crumpton, J. C., Seiler, J., Edmonson, M., Wu, G., et al. Mammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck Nature Communications 2015 6:6553 DOI:10.1038/ncomms7553 PMID:25850788 PMCID:PMC4403340
- Ambepitiya Wickramasinghe, I. N., de Vries, R. P., Weerts, E. A. W. S., van Beurden, S. J., Peng, W., McBride, R., Ducatez, M., Guy, J., Brown, P., Eterradossi, N., Grone, A., Paulson, J. C., et al. Novel receptor specificity of avian Gammacoronaviruses that cause enteritis Journal of Virology 2015 89:8783-8792 DOI:10.1128/jvi.00745-15 PMID:26063435 PMCID:PMC4524090
- Wesener, D. A., Wangkanont, K., McBride, R., Song, X., Kraft, M. B., Hodges, H. L., Zarling, L. C., Splain, R. A., Smith, D. F., Cummings, R. D., Paulson, J. C., Forest, K. T., et al. Recognition of microbial glycans by human intelectin-1 Nature Structural & Molecular Biology 2015 22:603-610 DOI:10.1038/nsmb.3053 PMID:26148048 PMCID:PMC4526365
- Tzarum, N., de Vries, R. P., Zhu, X., Yu, W., McBride, R., Paulson, J. C., Wilson, I. A. Structure and receptor binding of the hemagglutinin from a human H6N1 influenza virus Cell Host & Microbe 2015 17:369-376 DOI:10.1016/j.chom.2015.02.005 PMID:25766295 PMCID:PMC4374348
- Macauley, M. S., Kawasaki, N., Peng, W., Wang, S. H., He, Y., Arlian, B. M., McBride, R., Kannagi, R., Khoo, K. H., Paulson, J. C. Unmasking of CD22 co-receptor on germinal center B-cells occurs by alternative mechanisms in mouse and man Journal of Biological Chemistry 2015 290:30066-30077 DOI:10.1074/jbc.M115.691337 PMID:26507663 PMCID:PMC4705971
- Falkowska, E., Le, K. M., Ramos, A., Doores, K. J., Lee, J. H., Blattner, C., Ramirez, A., Derking, R., van Gils, M. J., Liang, C. H., McBride, R., von Bredow, B., et al. Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers Immunity 2014 40:657-668 DOI:10.1016/j.immuni.2014.04.009 PMID:24768347 PMCID:PMC4070425
- Rillahan, C. D., Macauley, M. S., Schwartz, E., He, Y., McBride, R., Arlian, B. M., Rangarajan, J., Fokin, V. V., Paulson, J. C. Disubstituted sialic acid ligands targeting siglecs CD33 and CD22 associated with myeloid leukaemias and B cell lymphomas Chemical Science 2014 5:2398-2406 DOI:10.1039/c4sc00451e PMID:24921038 PMCID:PMC4048721
- de Vries, R. P., Zhu, X., McBride, R., Rigter, A., Hanson, A., Zhong, G., Hatta, M., Xu, R., Yu, W., Kawaoka, Y., de Haan, C. A. M., Wilson, I. A., et al. Hemagglutinin receptor specificity and structural analyses of respiratory droplet-transmissible H5N1 viruses Journal of Virology 2014 88:768-773 DOI:10.1128/jvi.02690-13 PMID:24173215 PMCID:PMC3911709
- Macauley, M. S., Paulson, J. C. Immunology: Glyco-engineering 'super-self' Nature Chemical Biology 2014 10:7-8 DOI:10.1038/nchembio.1415 PMID:24346034 PMCID:PMC3935795
- York, W. S., Agravat, S., Aoki-Kinoshita, K. F., McBride, R., Campbell, M. P., Costello, C. E., Dell, A., Feizi, T., Haslam, S. M., Karlsson, N., Khoo, K. H., Kolarich, D., et al. MIRAGE: The Minimum Information Required for A Glycomics Experiment Glycobiology 2014 24:402-406 DOI:10.1093/glycob/cwu018 PMID:24653214 PMCID:PMC3976285
- Stowell, S. R., Arthur, C. M., McBride, R., Berger, O., Razi, N., Heimburg-Molinaro, J., Rodrigues, L. C., Gourdine, J. P., Noll, A. J., von Gunten, S., Smith, D. F., Knirel, Y. A., et al. Microbial glycan microarrays define key features of host-microbial interactions Nature Chemical Biology 2014 10:470-476 DOI:10.1038/nchembio.1525 PMID:24814672 PMCID:PMC4158828
- Macauley, M. S., Crocker, P. R., Paulson, J. C. Siglec-mediated regulation of immune cell function in disease Nature Reviews Immunology 2014 14:653-666 DOI:10.1038/nri3737 PMID:25234143 PMCID:PMC4191907
- Macauley, M. S., Paulson, J. C. Siglecs induce tolerance to cell surface antigens by BIM-dependent deletion of the antigen-reactive B cells Journal of Immunology 2014 193:4312-4321 DOI:10.4049/jimmunol.1401723 PMID:25252961 PMCID:PMC4201975
- Blattner, C., Lee, J. H., Sliepen, K., Derking, R., Falkowska, E., de la Pena, A. T., Cupo, A., Julien, J. P., van Gils, M., Lee, P. S., Peng, W., Paulson, J. C., et al. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers Immunity 2014 40:669-680 DOI:10.1016/j.immuni.2014.04.008 PMID:24768348 PMCID:PMC4057017
- Garces, F., Sok, D., Kong, L., McBride, R., Kim, H. J., Saye-Francisco, K. F., Julien, J. P., Hua, Y., Cupo, A., Moore, J. P., Paulson, J. C., Ward, A. B., et al. Structural evolution of glycan recognition by a family of potent HIV antibodies Cell 2014 159:69-79 DOI:10.1016/j.cell.2014.09.009 PMID:25259921 PMCID:PMC4278586
- Macauley, M. S., Arlian, B. M., Rillahan, C. D., Pang, P. C., Bortell, N., Marcondes, M. C. G., Haslam, S. M., Dell, A., Paulson, J. C. Systemic blockade of sialylation in mice with a global inhibitor of sialyltransferases Journal of Biological Chemistry 2014 289:35149-35158 DOI:10.1074/jbc.M114.606517 PMID:25368325 PMCID:PMC4271204
- Kawasaki, N., Rillahan, C. D., Cheng, T. Y., Van Rhijn, I., Macauley, M. S., Moody, D. B., Paulson, J. C. Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation Journal of Immunology 2014 193:1560-1566 DOI:10.4049/jimmunol.1303278 PMID:25000981 PMCID:PMC4119498
- Lee, M., Kiefel, H., LaJevic, M. D., Macauley, M. S., O'Hara, E., Pan, J., Paulson, J. C., Butcher, E. C. Transcriptional programs of lymphoid tissue capillary and high endothelium reveal control mechanisms for lymphocyte homing Nature Immunology 2014 15:982-995 DOI:10.1038/ni.2983 PMID:25173345 PMCID:PMC4222088
- Wang, Z., Chinoy, Z. S., Ambre, S. G., Peng, W. J., McBride, R., de Vries, R. P., Glushka, J., Paulson, J. C., Boons, G. J. A general strategy for the chemoenzymatic synthesis of asymmetrically branched N-glycans Science 2013 341:379-383 DOI:10.1126/science.1236231 PMID:23888036 PMCID:PMC3826785
- Orr, S. L., Le, D., Long, J. M., Sobieszczuk, P., Ma, B., Tian, H., Fang, X. Q., Paulson, J. C., Marth, J. D., Varki, N. A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins Glycobiology 2013 23:363-380 DOI:10.1093/glycob/cws150 PMID:23118208 PMCID:PMC3605971
- Xu, R., Krause, J. C., McBride, R., Paulson, J. C., Crowe, J. E., Wilson, I. A. A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin Nature Structural & Molecular Biology 2013 20:363-370 DOI:10.1038/nsmb.2500 PMID:23396351 PMCID:PMC3594569
- Zhu, X., Guo, Y. H., Jiang, T., Wang, Y. D., Chan, K. H., Li, X. F., Yu, W., McBride, R., Paulson, J. C., Yuen, K. Y., Qin, C. F., Che, X. Y., et al. A unique and conserved neutralization epitope in H5N1 influenza viruses identified by an antibody against the A/Goose/Guangdong/1/96 hemagglutinin Journal of Virology 2013 87:12619-12635 DOI:10.1128/jvi.01577-13 PMID:24049169 PMCID:PMC3838140
- Macauley, M. S., Pfrengle, F., Rademacher, C., Nycholat, C. M., Gale, A. J., von Drygalski, A., Paulson, J. C. Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis Journal of Clinical Investigation 2013 123:3074-3083 DOI:10.1172/jci69187 PMID:23722906 PMCID:PMC3706185
- Julien, J. P., Sok, D., Khayat, R., Lee, J. H., Doores, K. J., Walker, L. M., Ramos, A., Diwanji, D. C., Pejchal, R., Cupo, A., Katpally, U., Depetris, R. S., et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans PLoS Pathogens 2013 9:e1003342 DOI:10.1371/journal.ppat.1003342 PMID:23658524 PMCID:PMC3642082
- Watanabe, T., Kiso, M., Fukuyama, S., Nakajima, N., Imai, M., Yamada, S., Murakami, S., Yamayoshi, S., Iwatsuki-Horimoto, K., Sakoda, Y., Takashita, E., McBride, R., et al. Characterization of H7N9 influenza A viruses isolated from humans Nature 2013 501:551-555 DOI:10.1038/nature12392 PMID:23842494 PMCID:PMC3891892
- Pfrengle, F., Macauley, M. S., Kawasaki, N., Paulson, J. C. Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22 Journal of Immunology 2013 191:1724-1731 DOI:10.4049/jimmunol.1300921 PMID:23836061 PMCID:PMC3735655
- de Vries, R. P., de Vries, E., Martinez-Romero, C., McBride, R., van Kuppeveld, F. J., Rottier, P. J. M., Garcia-Sastre, A., Paulson, J. C., de Haan, C. A. M. Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions Journal of Virology 2013 87:13868-13877 DOI:10.1128/jvi.01955-13 PMID:24109242 PMCID:PMC3838262
- Ramya, T. N. C., Weerapana, E., Cravatt, B. F., Paulson, J. C. Glycoproteomics enabled by tagging sialic acid- or galactose-terminated glycans Glycobiology 2013 23:211-221 DOI:10.1093/glycob/cws144 PMID:23070960 PMCID:PMC3531297
- Paulson, J. C., de Vries, R. P. H5N1 receptor specificity as a factor in pandemic risk Virus Research 2013 178:99-113 DOI:10.1016/j.virusres.2013.02.015 PMID:23619279 PMCID:PMC3805702
- Zhu, X. Y., Yu, W. L., McBride, R., Li, Y., Chen, L. M., Donis, R. O., Tong, S. X., Paulson, J. C., Wilson, I. A. Hemagglutinin homologue from h17n10 bat influenza virus exhibits divergent receptor-binding and ph-dependent fusion activities Proceedings of the National Academy of Sciences of the United States of America 2013 110:1458-1463 DOI:10.1073/pnas.1218509110 PMID:23297216 PMCID:PMC3557073
- Tong, S., Zhu, X., Li, Y., Shi, M., Zhang, J., Bourgeois, M., Yang, H., Chen, X., Recuenco, S., Gomez, J., Chen, L. M., Johnson, A., et al. New world bats harbor diverse influenza A viruses PLoS Pathogens 2013 9:e1003657 DOI:10.1371/journal.ppat.1003657 PMID:24130481 PMCID:PMC3794996
- Rillahan, C. D., Schwartz, E., Rademacher, C., McBride, R., Rangarajan, J., Fokin, V. V., Paulson, J. C. On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7 ACS Chemical Biology 2013 8:1417-1422 DOI:10.1021/cb400125w PMID:23597400 PMCID:PMC3751994
- Xu, R., de Vries, R. P., Zhu, X., Nycholat, C. M., McBride, R., Yu, W., Paulson, J. C., Wilson, I. A. Preferential recognition of avian-like receptors in human influenza A H7N9 viruses Science 2013 342:1230-1235 DOI:10.1126/science.1243761 PMID:24311689 PMCID:PMC3954636
- Lu, X. S., Qi, J. X., Shi, Y., Wang, M., Smith, D. F., Heimburg-Molinaro, J., Zhang, Y. F., Paulson, J. C., Xiao, H. X., Gao, G. F. Structure and receptor binding specificity of hemagglutinin H13 from avian influenza A virus H13N6 Journal of Virology 2013 87:9077-9085 DOI:10.1128/jvi.00235-13 PMID:23760233 PMCID:PMC3754077
- Kong, L., Lee, J. H., Doores, K. J., Murin, C. D., Julien, J. P., McBride, R., Liu, Y., Marozsan, A., Cupo, A., Klasse, P. J., Hoffenberg, S., Caulfield, M., et al. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 Nature Structural & Molecular Biology 2013 20:796-803 DOI:10.1038/nsmb.2594 PMID:23708606 PMCID:PMC3823233
- Nycholat, C. M., Peng, W., McBride, R., Antonopoulos, A., de Vries, R. P., Polonskaya, Z., Finn, M. G., Dell, A., Haslam, S. M., Paulson, J. C. Synthesis of biologically active N- and O-linked glycans with multisialylated poly-N-acetyllactosamine extensions using P. damsela α2-6 sialyltransferase Journal of the American Chemical Society 2013 135:18280-18283 DOI:10.1021/ja409781c PMID:24256304 PMCID:PMC3901641
- Kawasaki, N., Vela, J. L., Nycholat, C. M., Rademacher, C., Khurana, A., van Rooijen, N., Crocker, P. R., Kronenberg, M., Paulson, J. C. Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation Proceedings of the National Academy of Sciences of the United States of America 2013 110:7826-7831 DOI:10.1073/pnas.1219888110 PMID:23610394 PMCID:PMC3651435
- Aoki-Kinoshita, K. F., Sawaki, H., An, H. J., Cho, J. W., Hsu, D., Kato, M., Kawano, S., Kawasaki, T., Khoo, K. H., Kim, J., Kim, J. D., Li, X. Y., et al. The third acgg-db meeting report: Towards an international collaborative infrastructure for glycobioinformatics Glycobiology 2013 23:144-146 DOI:10.1093/glycob/cws167 PMID:23271684 PMCID:PMC3988462
- Rademacher, C., Bru, T., McBride, R., Robison, E., Nycholat, C. M., Kremer, E. J., Paulson, J. C. A siglec-like sialic-acid-binding motif revealed in an adenovirus capsid protein Glycobiology 2012 22:1086-1091 DOI:10.1093/glycob/cws073 PMID:22522600 PMCID:PMC3382346
- Chen, W. H. C., Kawasaki, N., Nycholat, C. M., Han, S. F., Pilotte, J., Crocker, P. R., Paulson, J. C. Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/cd169 PLoS One 2012 7:e39039 DOI:10.1371/journal.pone.0039039 PMID:22723922 PMCID:PMC3378521
- Taylor, C. E., Cobb, B. A., Rittenhouse-Olson, K., Paulson, J. C., Schreiber, J. R. Carbohydrate moieties as vaccine candidates: Targeting the sweet spot in the immune response Vaccine 2012 30:4409-4413 DOI:10.1016/j.vaccine.2012.04.090 PMID:22575168
- Rillahan, C. D., Schwartz, E., McBride, R., Fokin, V. V., Paulson, J. C. Click and pick: identification of sialoside analogues for siglec-based cell targeting Angewandte Chemie-International Edition 2012 51:11014-11018 DOI:10.1002/anie.201205831 PMID:23038623 PMCID:PMC3480989
- Zhu, X. Y., Yang, H., Guo, Z., Yu, W. L., Carney, P. J., Li, Y., Chen, L. M., Paulson, J. C., Donis, R. O., Tong, S. X., Stevens, J., Wilson, I. A. Crystal structures of two subtype n10 neuraminidase-like proteins from bat influenza a viruses reveal a diverged putative active site Proceedings of the National Academy of Sciences of the United States of America 2012 109:18903-18908 DOI:10.1073/pnas.1212579109 PMID:23012478 PMCID:PMC3503178
- Xu, R., Zhu, X. Y., McBride, R., Nycholat, C. M., Yu, W. L., Paulson, J. C., Wilson, I. A. Functional balance of the hemagglutinin and neuraminidase activities accompanies the emergence of the 2009 h1n1 influenza pandemic Journal of Virology 2012 86:9221-9232 DOI:10.1128/jvi.00697-12 PMID:22718832 PMCID:PMC3416152
- Rillahan, C. D., Antonopoulos, A., Lefort, C. T., Sonon, R., Azadi, P., Ley, K., Dell, A., Haslam, S. M., Paulson, J. C. Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome Nature Chemical Biology 2012 8:661-668 DOI:10.1038/nchembio.999 PMID:22683610 PMCID:PMC3427410
- Rademacher, C., Paulson, J. C. Glycan fingerprints: Calculating diversity in glycan libraries ACS Chemical Biology 2012 7:829-834 DOI:10.1021/cb300003z PMID:22373368 PMCID:PMC3356451
- Rhee, J. K., Baksh, M., Nycholat, C., Paulson, J. C., Kitagishi, H., Finn, M. G. Glycan-targeted virus-like nanoparticles for photodynamic therapy Biomacromolecules 2012 13:2333-2338 DOI:10.1021/bm300578p PMID:22827531 PMCID:PMC3432587
- Peng, W. J., Pranskevich, J., Nycholat, C., Gilbert, M., Wakarchuk, W., Paulson, J. C., Razi, N. Helicobacter pylori beta 1,3-n-acetylglucosaminyltransferase for versatile synthesis of type 1 and type 2 poly-lacnacs on n-linked, o-linked and i-antigen glycans Glycobiology 2012 22:1453-1464 DOI:10.1093/glycob/cws101 PMID:22786570 PMCID:PMC3481905
- Nycholat, C. M., Rademacher, C., Kawasaki, N., Paulson, J. C. In silica-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages Journal of the American Chemical Society 2012 134:15696-15699 DOI:10.1021/ja307501e PMID:22967315 PMCID:PMC3462166
- Chen, L. M., Blixt, O., Stevens, J., Lipatov, A. S., Davis, C. T., Collins, B. E., Cox, N. J., Paulson, J. C., Donis, R. O. In vitro evolution of h5n1 avian influenza virus toward human-type receptor specificity Virology 2012 422:105-113 DOI:10.1016/j.virol.2011.10.006 PMID:22056389
- Zhu, X. Y., McBride, R., Nycholat, C. M., Yu, W. L., Paulson, J. C., Wilson, I. A. Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic acid receptors Journal of Virology 2012 86:13371-13383 DOI:10.1128/jvi.01426-12 PMID:23015718 PMCID:PMC3503043
- Nycholat, C. M., McBride, R., Ekiert, D. C., Xu, R., Rangarajan, J., Peng, W. J., Razi, N., Gilbert, M., Wakarchuk, W., Wilson, I. A., Paulson, J. C. Recognition of sialylated poly-n-acetyllactosamine chains on n- and o-linked glycans by human and avian influenza a virus hemagglutinins Angewandte Chemie-International Edition 2012 51:4860-4863 DOI:10.1002/anie.201200596 PMID:22505324 PMCID:PMC3517101
- Kiwamoto, T., Kawasaki, N., Paulson, J. C., Bochner, B. S. Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions Pharmacology & Therapeutics 2012 135:327-336 DOI:10.1016/j.pharmthera.2012.06.005 PMID:22749793 PMCID:PMC3587973
- Paulson, J. C., Macauley, M. S., Kawasaki, N. Siglecs as sensors of self in innate and adaptive immune responses Annals of the New York Academy of Sciences 2012 1253:37-48 DOI:10.1111/j.1749-6632.2011.06362.x PMID:22288608 PMCID:PMC3335958
- Xu, R., McBride, R., Nycholat, C. M., Paulson, J. C., Wilson, I. A. Structural characterization of the hemagglutinin receptor specificity from the 2009 h1n1 influenza pandemic Journal of Virology 2012 86:982-990 DOI:10.1128/jvi.06322-11 PMID:22072785 PMCID:PMC3255799
- Chen, W. H. C., Sigal, D. S., Saven, A., Paulson, J. C. Targeting b lymphoma with nanoparticles bearing glycan ligands of cd22 Leukemia & Lymphoma 2012 53:208-210 DOI:10.3109/10428194.2011.604755 PMID:21756025 PMCID:PMC3197974
- Rillahan, C. D., Paulson, J. C. Glycan microarrays for decoding the glycome Annual Review of Biochemistry 2011 80:797-823 DOI:10.1146/annurev-biochem-061809-152236 PMID:21469953 PMCID:PMC3116967
- Pejchal, R., Doores, K. J., Walker, L. M., Khayat, R., Huang, P. S., Wang, S. K., Stanfield, R. L., Julien, J. P., Ramos, A., Crispin, M., Depetris, R., Katpally, U., et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield Science 2011 334:1097-1103 DOI:10.1126/science.1213256 PMID:21998254 PMCID:PMC3280215
- O'Reilly, M. K., Tian, H., Paulson, J. C. Cd22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of b cells Journal of Immunology 2011 186:1554-1563 DOI:10.4049/jimmunol.1003005 PMID:21178016 PMCID:PMC3024466
- Kawasaki, N., Rademacher, C., Paulson, J. C. Cd22 regulates adaptive and innate immune responses of b cells Journal of Innate Immunity 2011 3:411-419 DOI:10.1159/000322375 PMID:21178327 PMCID:PMC3130896
- Abdu-Allah, H. H. M., Watanabe, K., Completo, G. C., Sadagopan, M., Hayashizaki, K., Takaku, C., Tamanaka, T., Takematsu, H., Kozutsumi, Y., Paulson, J. C., Tsubata, T., Ando, H., et al. Cd22-antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at c-2 and c-9 of sialic acid scaffold Bioorganic & Medicinal Chemistry 2011 19:1966-1971 DOI:10.1016/j.bmc.2011.01.060 PMID:21349726 PMCID:PMC3816717
- Rhee, J. K., Hovlid, M., Fiedler, J. D., Brown, S. D., Manzenrieder, F., Kitagishi, H., Nycholat, C., Paulson, J. C., Finn, M. G. Colorful virus-like particles: fluorescent protein packaging by the Qβ capsid Biomacromolecules 2011 12:3977-3981 DOI:10.1021/bm200983k PMID:21995513 PMCID:PMC3246388
- Maines, T. R., Chen, L. M., Van Hoeven, N., Tumpey, T. M., Blixt, O., Belser, J. A., Gustin, K. M., Pearce, M. B., Pappas, C., Stevens, J., Cox, N. J., Paulson, J. C., et al. Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza h5n1 viruses Virology 2011 413:139-147 DOI:10.1016/j.virol.2011.02.015 PMID:21397290
- Zeng, Y., Rademacher, C., Nycholat, C. M., Futakawa, S., Lemme, K., Ernst, B., Paulson, J. C. High affinity sialoside ligands of myelin associated glycoprotein Bioorganic & Medicinal Chemistry Letters 2011 21:5045-5049 DOI:10.1016/j.bmcl.2011.04.068 PMID:21561770 PMCID:PMC3156379
- Rillahan, C. D., Brown, S. J., Register, A. C., Rosen, H., Paulson, J. C. High-throughput screening for inhibitors of sialyl- and fucosyltransferases Angewandte Chemie-International Edition 2011 50:12534-12537 DOI:10.1002/anie.201105065 PMID:22095645 PMCID:PMC3245354
- Chen, L. M., Rivailler, P., Hossain, J., Carney, P., Balish, A., Perry, I., Davis, C. T., Garten, R., Shu, B., Xu, X. Y., Klimov, A., Paulson, J. C., et al. Receptor specificity of subtype h1 influenza a viruses isolated from swine and humans in the united states Virology 2011 412:401-410 DOI:10.1016/j.virol.2011.01.015 PMID:21333316
- Cui, L., Kitov, P. I., Completo, G. C., Paulson, J. C., Bundle, D. R. Supramolecular complexing of membane siglec cd22 mediated by a polyvalent heterobifunctional ligand that templates on igm Bioconjugate Chemistry 2011 22:546-550 DOI:10.1021/bc100579d PMID:21405019 PMCID:PMC3086123
- Kitazume, S., Imamaki, R., Ogawa, K., Komi, Y., Futakawa, S., Kojima, S., Hashimoto, Y., Marth, J. D., Paulson, J. C., Taniguchi, N. Alpha 2,6-sialic acid on platelet endothelial cell adhesion molecule (pecam) regulates its homophilic interactions and downstream antiapoptotic signaling Journal of Biological Chemistry 2010 285:6515-6521 DOI:10.1074/jbc.M109.073106 PMID:20048157 PMCID:PMC2825447
- Duong, B. H., Tian, H., Ota, T., Completo, G., Han, S. F., Vela, J. L., Ota, M., Kubitz, M., Bovin, N., Paulson, J., Nemazee, D. Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo Journal of Experimental Medicine 2010 207:173-187 DOI:10.1084/jem.20091873 PMID:20038598 PMCID:PMC2812539
- Astronomo, R. D., Kaltgrad, E., Udit, A. K., Wang, S. K., Doores, K. J., Huang, C. Y., Pantophlet, R., Paulson, J. C., Wong, C. H., Finn, M. G., Burton, D. R. Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds Chemistry & Biology 2010 17:357-370 DOI:10.1016/j.chembiol.2010.03.012 PMID:20416507 PMCID:PMC2867452
- Belisle, J. A., Horibata, S., Jennifer, G. A. A., Petrie, S., Kapur, A., Andre, S., Gabius, H. J., Rancourt, C., Connor, J., Paulson, J. C., Patankar, M. S. Identification of siglec-9 as the receptor for muc16 on human nk cells, b cells, and monocytes Molecular Cancer 2010 9:118 DOI:10.1186/1476-4598-9-118 PMID:20497550 PMCID:PMC2890604
- Ramya, T. N., Weerapana, E., Liao, L., Zeng, Y., Tateno, H., Yates, J. R., 3rd, Cravatt, B. F., Paulson, J. C. In situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics Molecular & Cellular Proteomics 2010 9:1339-1351 DOI:10.1074/mcp.M900461-MCP200 PMID:20172905 PMCID:PMC2877991
- Lindemann, L., Jacobsen, H., Schuhbauer, D., Knoflach, F., Gatti, S., Wettstein, J. G., Loetscher, H., Chu, T., Ebeling, M., Paulson, J. C., Prinssen, E., Brockhaus, M. In vitro pharmacological selectivity profile of oseltamivir prodrug (tamiflu (r)) and active metabolite European Journal of Pharmacology 2010 628:6-10 DOI:10.1016/j.ejphar.2009.11.020 PMID:19917275
- Chen, W. C., Completo, G. C., Sigal, D. S., Crocker, P. R., Saven, A., Paulson, J. C. In vivo targeting of b-cell lymphoma with glycan ligands of cd22 Blood 2010 115:4778-4786 DOI:10.1182/blood-2009-12-257386 PMID:20181615 PMCID:PMC2890185
- Tanaka, K., Siwu, E. R. O., Minami, K., Hasegawa, K., Nozaki, S., Kanayama, Y., Koyama, K., Chen, W. C., Paulson, J. C., Watanabe, Y., Fukase, K. Noninvasive imaging of dendrimer-type n-glycan clusters: In vivo dynamics dependence on oligosaccharide structure Angewandte Chemie-International Edition 2010 49:8195-8200 DOI:10.1002/anie.201000892 PMID:20857462
- Stevens, J., Chen, L. M., Carney, P. J., Garten, R., Foust, A., Le, J. H., Pokorny, B. A., Manojkumar, R., Silverman, J., Devis, R., Rhea, K., Xu, X. Y., et al. Receptor specificity of influenza a h3n2 viruses isolated in mammalian cells and embryonated chicken eggs Journal of Virology 2010 84:8287-8299 DOI:10.1128/jvi.00058-10 PMID:20519409 PMCID:PMC2916524
- Xu, R., McBride, R., Paulson, J. C., Basler, C. F., Wilson, I. A. Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 h2n2 pandemic Journal of Virology 2010 84:1715-1721 DOI:10.1128/jvi.02162-09 PMID:20007271 PMCID:PMC2812380
- Zeng, Y., Ramya, T. N. C., Dirksen, A., Dawson, P. E., Paulson, J. C. High-efficiency labeling of sialylated glycoproteins on living cells Nature Methods 2009 6:207-209 DOI:10.1038/nmeth.1305 PMID:19234450 PMCID:PMC2830088
- O'Reilly, M. K., Paulson, J. C. Siglecs as targets for therapy in immune-cell-mediated disease Trends in Pharmacological Sciences 2009 30:240-248 DOI:10.1016/j.tips.2009.02.005 PMID:19359050 PMCID:PMC2830709
- O'Reilly, M. K., Collins, B. E., Han, S., Liao, L., Rillahan, C., Kitov, P. I., Bundle, D. R., Paulson, J. C. Bifunctional CD22 ligands use multimeric immunoglobulins as protein scaffolds in assembly of immune complexes on B cells Journal of the American Chemical Society 2008 130:7736-7745 DOI:10.1021/ja802008q PMID:18505252 PMCID:PMC2574768
- Belser, J. A., Blixt, O., Chen, L. M., Pappas, C., Maines, T. R., Van Hoeven, N., Donis, R., Busch, J., McBride, R., Paulson, J. C., Katz, J. M., Tumpey, T. M. Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility Proceedings of the National Academy of Sciences of the United States of America 2008 105:7558-7563 DOI:10.1073/pnas.0801259105 PMID:18508975 PMCID:PMC2396559
- Kaltgrad, E., O'Reilly, M. K., Liao, L. A., Han, S. F., Paulson, J. C., Finn, M. G. On-virus construction of polyvalent glycan ligands for cell-surface receptors Journal of the American Chemical Society 2008 130:4578-4579 DOI:10.1021/ja077801n PMID:18341338
- Anthony, R. M., Nimmerjahn, F., Ashline, D. J., Reinhold, V. N., Paulson, J. C., Ravetch, J. V. Recapitulation of ivig anti-inflammatory activity with a recombinant igg fc Science 2008 320:373-376 DOI:10.1126/science.1154315 PMID:18420934 PMCID:PMC2409116
- Stevens, J., Blixt, O., Chen, L. M., Donis, R. O., Paulson, J. C., Wilson, I. A. Recent avian h5n1 viruses exhibit increased propensity for acquiring human receptor specificity Journal of Molecular Biology 2008 381:1382-1394 DOI:10.1016/j.jmb.2008.04.016 PMID:18672252 PMCID:PMC2519951
- Wan, H. Q., Sorrell, E. M., Song, H. C., Hossain, M. J., Ramirez-Nieto, G., Monne, I., Stevens, J., Cattoli, G., Capua, I., Chen, L. M., Donis, R. O., Busch, J., et al. Replication and transmission of h9n2 influenza viruses in ferrets: Evaluation of pandemic potential PLoS One 2008 3:e2923 DOI:10.1371/journal.pone.0002923 PMID:18698430 PMCID:PMC2500216
- Blixt, O., Han, S. F., Liao, L., Zeng, Y., Hoffmann, J., Futakawa, S., Paulson, J. C. Sialoside analogue arrays for rapid identification of high affinity siglec ligands Journal of the American Chemical Society 2008 130:6680-6681 DOI:10.1021/ja80l052g PMID:18452295 PMCID:PMC2614358
- Tateno, H., Li, H. Y., Schur, M. J., Bovin, N., Crocker, P. R., Wakarchuk, W. W., Paulson, J. C. Distinct endocytic mechanisms of cd22 (siglec-2) and siglec-f reflect roles in cell signaling and innate immunity Molecular and Cellular Biology 2007 27:5699-5710 DOI:10.1128/mcb.00383-07 PMID:17562860
- Glaser, L., Conenello, G., Paulson, J., Palese, P. Effective replication of human influenza viruses in mice lacking a major alpha 2,6 sialyltransferase Virus Research 2007 126:9-18 DOI:10.1016/j.virusres.2007.01.011 PMID:17313986
- Crocker, P. R., Paulson, J. C., Varki, A. Siglecs and their roles in the immune system Nature Reviews Immunology 2007 7:255-266 DOI:10.1038/nri2056 PMID:17380156
- Comelli, E. M., Head, S. R., Gilmartin, T., Whisenant, T., Haslam, S. M., North, S. J., Wong, N. K., Kudo, T., Narimatsu, H., Esko, J. D., Drickamer, K., Dell, A., et al. A focused microarray approach to functional glycomics: Transcriptional regulation of the glycome Glycobiology 2006 16:117-131 DOI:10.1093/glycob/cwj048 PMID:16237199
- Collins, B. E., Smith, B. A., Bengtson, P., Paulson, J. C. Ablation of cd22 in ligand-deficient mice restores b cell receptor signaling Nature Immunology 2006 7:199-206 DOI:10.1038/ni1283 PMID:16369536
- Comelli, E. M., Sutton-Smith, M., Yan, Q., Amado, M., Panico, M., Gilmartin, T., Whisenant, T., Lanigan, C. M., Head, S. R., Goldberg, D., Morris, H. R., Dell, A., et al. Activation of murine cd4(+) and cd8(+) t lymphocytes leads to dramatic remodeling of n-linked glycans Journal of Immunology 2006 177:2431-2440 PMID:16888005
- Stevens, J., Blixt, O., Glaser, L., Taubenberger, J. K., Palese, P., Paulson, J. C., Wilson, I. A. Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities Journal of Molecular Biology 2006 355:1143-1155 DOI:10.1016/j.jmb.2005.11.002 PMID:16343533
- Stevens, J., Blixt, O., Paulson, J. C., Wilson, I. A. Glycan microarray technologies: Tools to survey host specificity of influenza viruses Nature Reviews Microbiology 2006 4:857-864 DOI:10.1038/nrmicro1530 PMID:17013397
- Collins, B. E., Blixt, O., Han, S. F., Duong, B., Li, H. Y., Nathan, J. K., Bovin, N., Paulson, J. C. High-affinity ligand probes of cd22 overcome the threshold set by cis ligands for binding, endocytosis, and killing of b cells Journal of Immunology 2006 177:2994-3003 PMID:16920935
- Stevens, J., Blixt, O., Tumpey, T. M., Taubenberger, J. K., Paulson, J. C., Wilson, I. A. Structure and receptor specificity of the hemagglutinin from an h5n1 influenza virus Science 2006 312:404-410 DOI:10.1126/science.1124513 PMID:16543414
- Paulson, J. C., Blixt, O., Collins, B. E. Sweet spots in functional glycomics Nature Chemical Biology 2006 2:238-248 DOI:10.1038/nchembio785 PMID:16619023
- Goldberg, D., Sutton-Smith, M., Paulson, J., Dell, A. Automatic annotation of matrix-assisted laser desorption/ionization n-glycan spectra Proteomics 2005 5:865-875 DOI:10.1002/pmic.200401071 PMID:15693066
- Blixt, O., Vasiliu, D., Allin, K., Jacobsen, N., Warnock, D., Razi, N., Paulson, J. C., Bernatchez, S., Gilbert, M., Wakarchuk, W. Chemoenzymatic synthesis of 2-azidoethyl-ganglio-oligosaccharides gd3, gt3, gm2, gd2, gt2, gm1, and gd1a Carbohydrate Research 2005 340:1963-1972 DOI:10.1016/j.carres.2005.06.008 PMID:16005859
- Raman, R., Raguram, S., Venkataraman, G., Paulson, J. C., Sasisekharan, R. Glycomics: An integrated systems approach to structure-function relationships of glycans Nature Methods 2005 2:817-824 DOI:10.1038/nmeth807 PMID:16278650
- Han, S., Collins, B. E., Bengtson, P., Paulson, J. C. Homomultimeric complexes of cd22 in b cells revealed by protein-glycan cross-linking Nature Chemical Biology 2005 1:93-97 DOI:10.1038/nchembio713 PMID:16408005
- Kitazume, S., Nakagawa, K., Oka, R., Tachida, Y., Ogawa, K., Luo, Y., Citron, M., Shitara, H., Taya, C., Yonekawa, H., Paulson, J. C., Miyoshi, E., et al. In vivo cleavage of alpha 2,6-sialyltransferase by alzheimer beta-secretase Journal of Biological Chemistry 2005 280:8589-8595 PMID:15364953
- Tateno, H., Crocker, P. R., Paulson, J. C. Mouse siglec-f and human siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6 '-sulfo-sialyl lewis x as a preferred glycan ligand Glycobiology 2005 15:1125-1135 DOI:10.1093/glycob/cwi097 PMID:15972893
- Vyas, A. A., Blixt, O., Paulson, J. C., Schnaar, R. L. Potent glycan inhibitors of myelin-associated glycoprotein enhance axon outgrowth in vitro Journal of Biological Chemistry 2005 280:16305-16310 DOI:10.1074/jbc.M500250200 PMID:15701648 PMCID:PMC1852507
- Shen, Z. X., Go, E. P., Gamez, A., Apon, J. V., Fokin, V., Greig, M., Ventura, M., Crowell, J. E., Blixt, O., Paulson, J. C., Stevens, R. C., Finn, M. G., et al. A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a desorption/ionization on silicon (DIOS) platform ChemBioChem 2004 5:921-927 DOI:10.1002/cbic.200400008 PMID:15239048
- Collins, B. E., Paulson, J. C. Cell surface biology mediated by low affinity multivalent protein-glycan interactions Current Opinion in Chemical Biology 2004 8:617-625 DOI:10.1016/j.cbpa.2004.10.004 PMID:15556405
- Bryan, M. C., Fazio, F., Lee, H. K., Huang, C. Y., Chang, A., Best, M. D., Calarese, D. A., Blixt, C., Paulson, J. C., Burton, D., Wilson, I. A., Wong, C. H. Covalent display of oligosaccharide arrays in microtiter plates Journal of the American Chemical Society 2004 126:8640-8641 DOI:10.1021/ja048433f PMID:15250702
- Collins, B. E., Blixt, O., DeSieno, A. R., Bovin, N., Marth, J. D., Paulson, J. C. Masking of cd22 by cis ligands does not prevent redistribution of cd22 to sites of cell contact Proceedings of the National Academy of Sciences of the United States of America 2004 101:6104-6109 DOI:10.1073/pnas.0400851101 PMID:15079087 PMCID:PMC395930
- Ikehara, Y., Ikehara, S. K., Paulson, J. C. Negative regulation of t cell receptor signaling by siglec-7 (p70/airm) and siglec-9 Journal of Biological Chemistry 2004 279:43117-43125 DOI:10.1074/jbc.M403538200 PMID:15292262
- Amado, M., Yan, Q., Comelli, E. M., Collins, B. E., Paulson, J. C. Peanut agglutinin high phenotype of activated cd8(+) t cells results from de novo synthesis of cd45 glycans Journal of Biological Chemistry 2004 279:36689-36697 DOI:10.1074/jbc.M405629200 PMID:15210702
- Blixt, O., Head, S., Mondala, T., Scanlan, C., Huflejt, M. E., Alvarez, R., Bryan, M. C., Fazio, F., Calarese, D., Stevens, J., Razi, N., Stevens, D. J., et al. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins Proceedings of the National Academy of Sciences of the United States of America 2004 101:17033-17038 DOI:10.1073/pnas.0407902101 PMID:15563589 PMCID:PMC534418
- Blixt, O., Paulson, J. C. Biocatalytic preparation of n-glycolylneuraminic acid, deaminoneuraminic acid (kdn) and 9-azido-9-deoxysialic acid oligosaccharides Advanced Synthesis & Catalysis 2003 345:687-690 DOI:10.1002/adsc.200303032
- Comelli, E. M., Amado, M., Lustig, S. R., Paulson, J. C. Identification and expression of neu4, a novel murine sialidase Gene 2003 321:155-161 DOI:10.1016/j.gene.2003.08.005 PMID:14637003
- Blixt, O., Collins, B. E., van den Nieuwenhof, I. M., Crocker, P. R., Paulson, J. C. Sialoside specificity of the siglec family assessed using novel multivalent probes - identification of potent inhibitors of myelin-associated glycoprotein Journal of Biological Chemistry 2003 278:31007-31019 DOI:10.1074/jbc.M304331200 PMID:12773526
- Zuber, C., Paulson, J. C., Toma, V., Winter, H. C., Goldstein, I. J., Roth, J. Spatiotemporal expression patterns of sialoglycoconjugates during nephron morphogenesis and their regional and cell type-specific distribution in adult rat kidney Histochemistry and Cell Biology 2003 120:143-160 DOI:10.1007/s00418-003-0553-0 PMID:12898273
- Kalovidouris, S. A., Blixt, O., Nelson, A., Vidal, S., Turnbull, W. B., Paulson, J. C., Stoddart, J. F. Synthetic carbohydrate dendrimers, part 11. Chemically defined sialoside scaffolds for investigation of multivalent interactions with sialic acid binding proteins Journal of Organic Chemistry 2003 68:8485-8493 DOI:10.1021/jo030203g PMID:14575475
- Danzer, C. P., Collins, B. E., Blixt, O., Paulson, J. C., Nitschke, L. Transitional and marginal zone b cells have a high proportion of unmasked cd22: Implications for bcr signaling International Immunology 2003 15:1137-1147 DOI:10.1093/intimm/dxg114 PMID:13679384
- Saito, S., Yamashita, S. I., Endoh, M., Yamato, T., Hoshi, S., Ohyama, C., Watanabe, R., Ito, A., Satoh, M., Wada, T., Paulson, J. C., Arai, Y., et al. Clinical significance of st3gal iv expression in human renal cell carcinoma Oncology Reports 2002 9:1251-1255 PMID:12375029
- Collins, B. E., Blixt, O., Bovin, N. V., Danzer, C. P., Chui, D., Marth, J. D., Nitschke, L., Paulson, J. C. Constitutively unmasked cd22 on b cells of st6gal i knockout mice: Novel sialoside probe for murine cd22 Glycobiology 2002 12:563-571 DOI:10.1093/glycob/cwf067 PMID:12213789
- Blixt, O., Allin, K., Pereira, L., Datta, A., Paulson, J. C. Efficient chemoenzymatic synthesis of o-linked sialyl oligosaccharides Journal of the American Chemical Society 2002 124:5739-5746 DOI:10.1021/ja017881+ PMID:12010048
- Lee, K. J., Mao, S. L., Sun, C. Z., Gao, C., Blixt, O., Arrues, S., Hom, L. G., Kaufmann, G. F., Hoffman, T. Z., Coyle, A. R., Paulson, J., Felding-Habermann, B., et al. Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen Journal of the American Chemical Society 2002 124:12439-12446 DOI:10.1021/ja020737j PMID:12381184
- Dormitzer, P. R., Sun, Z. Y. J., Blixt, O., Paulson, J. C., Wagner, G., Harrison, S. C. Specificity and affinity of sialic acid binding by the rhesus rotavirus vp8*core Journal of Virology 2002 76:10512-10517 DOI:10.1128/jvi.76.20.10512-10517.2002 PMID:12239329
- Fazio, F., Bryan, M. C., Blixt, O., Paulson, J. C., Wong, C. H. Synthesis of sugar arrays in microtiter plate Journal of the American Chemical Society 2002 124:14397-14402 DOI:10.1021/ja020887u PMID:12452714
- Datta, A. K., Chammas, R., Paulson, J. C. Conserved cysteines in the sialyltransferase sialylmotifs form an essential disulfide bond Journal of Biological Chemistry 2001 276:15200-15207 DOI:10.1074/jbc.M010542200 PMID:11278697
- Blixt, O., Brown, J., Schur, M. J., Wakarchuk, W., Paulson, J. C. Efficient preparation of natural and synthetic galactosides with a recombinant beta-1,4-galactosyltransferase-/udp-4 '-gal epimerase fusion protein Journal of Organic Chemistry 2001 66:2442-2448 DOI:10.1021/jo0057809 PMID:11281786
- Alexander, J., del Guercio, M. F., Maewal, A., Qiao, L., Fikes, J., Chesnut, R. W., Paulson, J., Bundle, D. R., DeFrees, S., Sette, A. Linear padre t helper epitope and carbohydrate b cell epitope conjugates induce specific high titer igg antibody responses Journal of Immunology 2000 164:1625-1633 PMID:10640784
- Talbott, G. A., Sharar, S. R., Paulson, J. C., Harlan, J. M., Winn, R. K. Antibiotic therapy determines subcutaneous escherichia coli abscess formation after cd18 inhibition in rabbits Journal of Burn Care & Rehabilitation 1998 19:284-291 DOI:10.1097/00004630-199807000-00003 PMID:9710724
- Hennet, T., Chui, D., Paulson, J. C., Marth, J. D. Immune regulation by the st6gal sialyltransferase Proceedings of the National Academy of Sciences of the United States of America 1998 95:4504-4509 DOI:10.1073/pnas.95.8.4504 PMID:9539767
- Ito, T., Couceiro, Jnss, Kelm, S., Baum, L. G., Krauss, S., Castrucci, M. R., Donatelli, I., Kida, H., Paulson, J. C., Webster, R. G., Kawaoka, Y. Molecular basis for the generation in pigs of influenza a viruses with pandemic potential Journal of Virology 1998 72:7367-7373 PMID:9696833 PMCID:PMC109961
- Datta, A. K., Sinha, A., Paulson, J. C. Mutation of the sialyltransferase s-sialylmotif alters the kinetics of the donor and acceptor substrates Journal of Biological Chemistry 1998 273:9608-9614 DOI:10.1074/jbc.273.16.9608 PMID:9545292
- Datta, A. K., Paulson, J. C. Sialylmotifs of sialyltransferases Indian Journal of Biochemistry & Biophysics 1997 34:157-165 PMID:9343944
- Kitagawa, H., Mattei, M. G., Paulson, J. C. Genomic organization and chromosomal mapping of the gal beta 1,3galnac/gal beta 1,4glcnac alpha 2,3-sialyltransferase Journal of Biological Chemistry 1996 271:931-938 PMID:8557707
- Sjoberg, E. R., Kitagawa, H., Glushka, J., vanHalbeek, H., Paulson, J. C. Molecular cloning of a developmentally regulated n-acetylgalactosamine alpha 2,6-sialyltransferase specific for sialylated glycoconjugates Journal of Biological Chemistry 1996 271:7450-7459 PMID:8631773
- Wakefield, T. W., Strieter, R. M., Downing, L. J., Kadell, A. M., Wilke, C. A., Burdick, M. D., Wrobleski, S. K., Phillips, M. L., Paulson, J. C., Anderson, D. C., Greenfield, L. J. P-selectin and tnf inhibition reduce venous thrombosis inflammation Journal of Surgical Research 1996 64:26-31 DOI:10.1006/jsre.1996.0301 PMID:8806469
- Tojo, S. J., Yokota, S., Koike, H., Schultz, J., Hamazume, Y., Misugi, E., Yamada, K., Hayashi, M., Paulson, J. C., Morooka, S. Reduction of rat myocardial ischemia and reperfusion injury by sialyl lewis x oligosaccharide and anti-rat p-selectin antibodies Glycobiology 1996 6:463-469 DOI:10.1093/glycob/6.4.463 PMID:8842711
- Tsuji, S., Datta, A. K., Paulson, J. C. Systematic nomenclature for sialyltransferases Glycobiology 1996 6:v-vii PMID:8953271
- Murohara, T., Margiotta, J., Phillips, L. M., Paulson, J. C., DeFrees, S., Zalipsky, S., Guo, L. S. S., Lefer, A. M. Cardioprotection by liposome-conjugated sialyl lewis(x)-oligosaccharide in myocardial ischaemia and reperfusion injury Cardiovascular Research 1995 30:965-974 DOI:10.1016/s0008-6363(95)00157-3 PMID:8746213
- Williams, M. A., Kitagawa, H., Datta, A. K., Paulson, J. C., Jamieson, J. C. Large-scale expression of recombinant sialyttransferases and comparison of their kinetic-properties with native enzymes Glycoconjugate Journal 1995 12:755-761 DOI:10.1007/bf00731235 PMID:8748151
- Defrees, S. A., Kosch, W., Way, W., Paulson, J. C., Sabesan, S., Halcomb, R. L., Huang, D. H., Ichikawa, Y., Wong, C. H. Ligand recognition by e-selectin - synthesis, inhibitory activity, and conformational-analysis of bivalent sialyl-lewis-x analogs Journal of the American Chemical Society 1995 117:66-79 DOI:10.1021/ja00106a008
- Phillips, M. L., Schwartz, B. R., Etzioni, A., Bayer, R., Ochs, H. D., Paulson, J. C., Harlan, J. M. Neutrophil adhesion in leukocyte adhesion deficiency syndrome type 2 Journal of Clinical Investigation 1995 96:2898-2906 DOI:10.1172/jci118361 PMID:8675661
- Leigh, M. W., Connor, R. J., Kelm, S., Baum, L. G., Paulson, J. C. Receptor specificity of influenza-virus influences severity of illness in ferrets Vaccine 1995 13:1468-1473 DOI:10.1016/0264-410x(95)00004-k PMID:8578828
- Datta, A. K., Paulson, J. C. The sialyltransferase sialylmotif participates in binding the donor substrate cmp-neuac Journal of Biological Chemistry 1995 270:1497-1500 PMID:7829476
- Winn, R. K., Paulson, J. C., Harlan, J. M. A monoclonal antibody to P-selectin ameliorates injury associated with hemorrhagic shock in rabbits American Journal of Physiology-Heart and Circulatory Physiology 1994 267:H2391-H2397 PMID:7528995
- Gaudino, J. J., Paulson, J. C. A novel and efficient synthesis of neolacto series gangliosides 3'-nlm(1) and 6'nlm(1) Journal of the American Chemical Society 1994 116:1149-1150 DOI:10.1021/ja00082a054
- Unverzagt, C., Kelm, S., Paulson, J. C. Chemical and enzymatic-synthesis of multivalent sialoglycopeptides Carbohydrate Research 1994 251:285-301 DOI:10.1016/0008-6215(94)84292-2 PMID:8149376
- Kitagawa, H., Paulson, J. C. Cloning of a novel alpha-2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups Journal of Biological Chemistry 1994 269:1394-1401 PMID:8288606
- Kurose, I., Pothoulakis, C., Lamont, J. T., Anderson, D. C., Paulson, J. C., Miyasaka, M., Wolf, R., Granger, D. N. Clostridium-difficile toxin a-induced microvascular dysfunction - role of histamine Journal of Clinical Investigation 1994 94:1919-1926 DOI:10.1172/jci117542 PMID:7962537
- Kitagawa, H., Paulson, J. C. Differential expression of 5 sialyltransferase genes in human tissues Journal of Biological Chemistry 1994 269:17872-17878 PMID:8027041
- Zimmerman, B. J., Holt, J. W., Paulson, J. C., Anderson, D. C., Miyasaka, M., Tamatani, T., Todd, R. F., Rusche, J. R., Granger, D. N. Molecular determinants of lipid mediator-induced leukocyte adherence and emigration in rat mesenteric venules American Journal of Physiology 1994 266:H847-H853 PMID:8160832
- Kurose, I., Anderson, D. C., Miyasaka, M., Tamatani, T., Paulson, J. C., Todd, R. F., Rusche, J. R., Granger, D. N. Molecular determinants of reperfusion-induced leukocyte adhesion and vascular protein leakage Circulation Research 1994 74:336-343 PMID:7507416
- Jerome, S. N., Dore, M., Paulson, J. C., Smith, C. W., Korthuis, R. J. P-selectin and icam-1-dependent adherence reactions - role in the genesis of postischemic no-reflow American Journal of Physiology 1994 266:H1316-H1321 PMID:7514358
- Connor, R. J., Kawaoka, Y., Webster, R. G., Paulson, J. C. Receptor specificity in human, avian, and equine h2 and h3 influenza-virus isolates Virology 1994 205:17-23 DOI:10.1006/viro.1994.1615 PMID:7975212
- Asako, H., Kurose, I., Wolf, R., Defrees, S., Zheng, Z. L., Phillips, M. L., Paulson, J. C., Granger, D. N. Role of h1 receptors and p-selectin in histamine-induced leukocyte rolling and adhesion in postcapillary venules Journal of Clinical Investigation 1994 93:1508-1515 DOI:10.1172/jci117129 PMID:7512982
- Seekamp, A., Till, G. O., Mulligan, M. S., Paulson, J. C., Anderson, D. C., Miyasaka, M., Ward, P. A. Role of selectins in local and remote tissue injury following ischemia and reperfusion American Journal of Pathology 1994 144:592-598 PMCID:PMC7510457
- Sabesan, S., Paulson, J. C., Weinstein, J. Separation of gal-beta-1,4glcnac-alpha-2,6-sialyltransferase and gal-beta-1,3(4)glcnac-alpha-2,3-sialyltransferase by affinity-chromatography Methods in Enzymology 1994 247:237-243 PMID:7898356
- Skurk, C., Buerke, M., Guo, J. P., Paulson, J., Lefer, A. M. Sialyl Lewisx-containing oligosaccharide exerts beneficial effects in murine traumatic shock American Journal of Physiology-Heart and Circulatory Physiology 1994 267:H2124-H2131 PMID:7528988
- Schuster, M., Wang, P., Paulson, J. C., Wong, C. H. Solid-phase chemical-enzymatic synthesis of glycopeptides and oligosaccharides Journal of the American Chemical Society 1994 116:1135-1136 DOI:10.1021/ja00082a047
- Zimmerman, B. J., Paulson, J. C., Arrhenius, T. S., Gaeta, F. C. A., Granger, D. N. Thrombin receptor peptide-mediated leukocyte rolling in rat mesenteric venules - roles of p-selectin and sialyl-lewis-x American Journal of Physiology 1994 267:H1049-H1053 PMID:7522405
- Herrmann, G. F., Ichikawa, Y., Wandrey, C., Gaeta, F. C. A., Paulson, J. C., Wong, C. H. A new multienzyme system for a one-pot synthesis of sialyl oligosaccharides - combined use of beta-galactosidase and alpha(2,6)-sialyltransferase coupled with regeneration insitu of cmp-sialic acid Tetrahedron Letters 1993 34:3091-3094 DOI:10.1016/s0040-4039(00)93387-2
- Ito, Y., Paulson, J. C. A novel strategy for synthesis of ganglioside-gm3 using an enzymatically produced sialoside glycosyl donor Journal of the American Chemical Society 1993 115:1603-1605 DOI:10.1021/ja00057a071
- Winn, R. K., Liggitt, D., Vedder, N. B., Paulson, J. C., Harlan, J. M. Anti-p-selectin monoclonal-antibody attenuates reperfusion injury to the rabbit ear Journal of Clinical Investigation 1993 92:2042-2047 DOI:10.1172/jci116799 PMID:7691890
- Kitagawa, H., Paulson, J. C. Cloning and expression of human gal-beta-1,3(4)glcnac alpha-2,3-sialyltransferase Biochemical and Biophysical Research Communications 1993 194:375-382 DOI:10.1006/bbrc.1993.1830 PMID:8333853
- Ito, Y., Paulson, J. C. Combined use of trans-sialidase and sialyltransferase for enzymatic-synthesis of alpha-neuac2-- 3-beta-gal-or Journal of the American Chemical Society 1993 115:7862-7863 DOI:10.1021/ja00070a036
- Palmer, D. H., Paulson, J. C., Lanelarsen, C. L., Peulen, V. K., Olson, J. D. Endoscopic carpal-tunnel release - a comparison of 2 techniques with open release Arthroscopy 1993 9:498-508 DOI:10.1016/s0749-8063(05)80396-2 PMID:8280321
- von Andrian, U. H., Berger, E. M., Ramezani, L., Chambers, J. D., Ochs, H. D., Harlan, J. M., Paulson, J. C., Etzioni, A., Arfors, K. E. In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes Journal of Clinical Investigation 1993 91:2893-2897 DOI:10.1172/jci116535 PMID:7685776 PMCID:PMC443360
- Nelson, J., Couceiro, S. S., Paulson, J. C., Baum, L. G. Influenza-virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium - the role of the host-cell in selection of hemagglutinin receptor specificity Virus Research 1993 29:155-165 PMID:8212857
- Kurose, I., Kubes, P., Wolf, R., Anderson, D. C., Paulson, J., Miyasaka, M., Granger, D. N. Inhibition of nitric-oxide production - mechanisms of vascular albumin leakage Circulation Research 1993 73:164-171 PMID:7685251
- Sharar, S. R., Sasaki, S. S., Flaherty, L. C., Paulson, J. C., Harlan, J. M., Winn, R. K. P-selectin blockade does not impair leukocyte host-defense against bacterial peritonitis and soft-tissue infection in rabbits Journal of Immunology 1993 151:4982-4988 PMID:7691961
- Livingston, B. D., Paulson, J. C. Polymerase chain-reaction cloning of a developmentally-regulated member of the sialyltransferase gene family Journal of Biological Chemistry 1993 268:11504-11507 PMID:7685014
- Mulligan, M. S., Paulson, J. C., Defrees, S., Zheng, Z. L., Lowe, J. B., Ward, P. A. Protective effects of oligosaccharides in P-selectin-dependent lung injury Nature 1993 364:149-151 DOI:10.1038/364149a0 PMID:7686631
- Mulligan, M. S., Lowe, J. B., Larsen, R. D., Paulson, J., Zheng, Z. L., Defrees, S., Maemura, K., Fukuda, M., Ward, P. A. Protective effects of sialylated oligosaccharides in immune-complex induced acute lung injury Journal of Experimental Medicine 1993 178:623-631 DOI:10.1084/jem.178.2.623 PMID:7688029
- Gillespie, W., Paulson, J. C., Kelm, S., Pang, M., Baum, L. G. Regulation of alpha-2,3-sialyltransferase expression correlates with conversion of peanut agglutinin (pna)+ to pna- phenotype in developing thymocytes Journal of Biological Chemistry 1993 268:3801-3804 PMID:8440675
- Wallace, J. L., McKnight, W., Miyasaka, M., Tamatani, T., Paulson, J., Anderson, D. C., Granger, D. N., Kubes, P. Role of endothelial adhesion molecules in nsaid-induced gastric-mucosal injury American Journal of Physiology 1993 265:G993-G998 PMID:7694504
- Aubin, Y., Ito, Y., Paulson, J. C., Prestegard, J. H. Structure and dynamics of the sialic-acid moiety of g(m3)-ganglioside at the surface of a magnetically oriented membrane Biochemistry 1993 32:13405-13413 DOI:10.1021/bi00212a005 PMID:8257677
- Ito, Y., Gaudino, J. J., Paulson, J. C. Synthesis of bioactive sialosides Pure and Applied Chemistry 1993 65:753-762 DOI:10.1351/pac199365040753
- Herrler, G., Gross, H. J., Imhof, A., Brossmer, R., Milks, G., Paulson, J. C. A synthetic sialic-acid analog is recognized by influenza-c virus as a receptor determinant but is resistant to the receptor-destroying enzyme Journal of Biological Chemistry 1992 267:12501-12505 PMID:1618756
- Ichikawa, Y., Lin, Y. C., Dumas, D. P., Shen, G. J., Garciajunceda, E., Williams, M. A., Bayer, R., Ketcham, C., Walker, L. E., Paulson, J. C., Wong, C. H. Chemical-enzymatic synthesis and conformational-analysis of sialyl lewis-x and derivatives Journal of the American Chemical Society 1992 114:9283-9298 DOI:10.1021/ja00050a007
- Gillespie, W., Kelm, S., Paulson, J. C. Cloning and expression of the gal-beta-1,3galnac alpha-2,3-sialyltransferase Journal of Biological Chemistry 1992 267:21004-21010 PMID:1383214
- Sabesan, S., Duus, J. O., Neira, S., Domaille, P., Kelm, S., Paulson, J. C., Bock, K. Cluster sialoside inhibitors for influenza-virus - synthesis, NMR, and biological studies Journal of the American Chemical Society 1992 114:8363-8375 DOI:10.1021/ja00048a004
- Mulligan, M. S., Polley, M. J., Bayer, R. J., Nunn, M. F., Paulson, J. C., Ward, P. A. Neutrophil-dependent acute lung injury. Requirement for P-selectin (GMP-140) Journal of Clinical Investigation 1992 90:1600-1607 DOI:10.1172/jci116029 PMID:1383277 PMCID:PMC443208
- Wen, D. X., Livingston, B. D., Medzihradszky, K. F., Kelm, S., Burlingame, A. L., Paulson, J. C. Primary structure of gal-beta-1,3(4)glcnac alpha-2,3-sialyltransferase determined by mass-spectrometry sequence-analysis and molecular-cloning - evidence for a protein motif in the sialyltransferase gene family Journal of Biological Chemistry 1992 267:21011-21019 PMID:1400416
- Etzioni, A., Frydman, M., Pollack, S., Avidor, I., Phillips, M. L., Paulson, J. C., Gershonibaruch, R. Recurrent severe infections caused by a novel leukocyte adhesion deficiency New England Journal of Medicine 1992 327:1789-1792 DOI:10.1056/nejm199212173272505 PMID:1279426
- Svensson, E. C., Conley, P. B., Paulson, J. C. Regulated expression of alpha-2,6-sialyltransferase by the liver-enriched transcription factors hnf-1, dbp, and lap Journal of Biological Chemistry 1992 267:3466-3472 PMID:1737800
- Colley, K. J., Lee, E. U., Paulson, J. C. The signal anchor and stem regions of the beta-galactoside alpha-2,6-sialyltransferase may each act to localize the enzyme to the golgi-apparatus Journal of Biological Chemistry 1992 267:7784-7793 PMID:1560012
- Wen, D. X., Svensson, E. C., Paulson, J. C. Tissue-specific alternative splicing of the beta-galactoside alpha-2,6-sialyltransferase gene Journal of Biological Chemistry 1992 267:2512-2518 PMID:1733948
- Kelm, S., Paulson, J. C., Rose, U., Brossmer, R., Schmid, W., Bandgar, B. P., Schreiner, E., Hartmann, M., Zbiral, E. Use of sialic-acid analogs to define functional-groups involved in binding to the influenza-virus hemagglutinin European Journal of Biochemistry 1992 205:147-153 DOI:10.1111/j.1432-1033.1992.tb16762.x PMID:1555576
- Polley, M. J., Phillips, M. L., Wayner, E., Nudelman, E., Singhal, A. K., Hakomori, S. I., Paulson, J. C. Cd62 and endothelial-cell leukocyte adhesion molecule-1 (elam-1) recognize the same carbohydrate ligand, sialyl-lewis-x Proceedings of the National Academy of Sciences of the United States of America 1991 88:6224-6228 DOI:10.1073/pnas.88.14.6224 PMID:1712483
- Nishi, T., Weinstein, J., Gillespie, W. M., Paulson, J. C. Complete primary structure of porcine tenascin - detection of tenascin transcripts in adult submaxillary-glands European Journal of Biochemistry 1991 202:643-648 DOI:10.1111/j.1432-1033.1991.tb16418.x PMID:1722152
- Sabesan, S., Bock, K., Paulson, J. C. Conformational-analysis of sialyloligosaccharides Carbohydrate Research 1991 218:27-54 DOI:10.1016/0008-6215(91)84084-r PMID:1802388
- Crocker, P. R., Kelm, S., Dubois, C., Martin, B., McWilliam, A. S., Shotton, D. M., Paulson, J. C., Gordon, S. Purification and properties of sialoadhesin, a sialic acid-binding receptor of murine tissue macrophages EMBO Journal 1991 10:1661-1669 PMID:2050106 PMCID:PMC452836
- Sabesan, S., Duus, J. O., Domaille, P., Kelm, S., Paulson, J. C. Synthesis of cluster sialoside inhibitors for influenza-virus Journal of the American Chemical Society 1991 113:5865-5866 DOI:10.1021/ja00015a052
- Kodama, H., Baum, L. G., Paulson, J. C. Synthesis of linkage-specific sialoside substrates for colorimetric assay of neuraminidases Carbohydrate Research 1991 218:111-119 DOI:10.1016/0008-6215(91)84090-2 PMID:1802382
- Pozsgay, V., Brisson, J. R., Jennings, H. J., Allen, S., Paulson, J. C. Synthetic oligosaccharides related to group-b streptococcal polysaccharides .5. Combined chemical and enzymatic-synthesis of a pentasaccharide repeating unit of the capsular polysaccharide of type-iii group-b streptococcus and one-dimensional and 2-dimensional NMR spectroscopic studies Journal of Organic Chemistry 1991 56:3377-3385 DOI:10.1021/jo00010a037
- Pozsgay, V., Gaudino, J., Paulson, J. C., Jennings, H. J. Synthetic oligosaccharides related to group-b streptococcal polysaccharides .6. Chemoenzymatic synthesis of a branching decasaccharide fragment of the capsular polysaccharide of type-iii group-b streptococcus Bioorganic & Medicinal Chemistry Letters 1991 1:391-394 DOI:10.1016/s0960-894x(00)80262-0
- Baum, L. G., Paulson, J. C. The n2 neuraminidase of human influenza-virus has acquired a substrate-specificity complementary to the hemagglutinin receptor specificity Virology 1991 180:10-15 DOI:10.1016/0042-6822(91)90003-t PMID:1984642
- Phillips, M. L., Nudelman, E., Gaeta, F. C. A., Perez, M., Singhal, A. K., Hakomori, S. I., Paulson, J. C. Elam-1 mediates cell-adhesion by recognition of a carbohydrate ligand, sialyl-lex Science 1990 250:1130-1132 DOI:10.1126/science.1701274 PMID:1701274
- Unverzagt, C., Kunz, H., Paulson, J. C. High-efficiency synthesis of sialyloligosaccharides and sialoglycopeptides Journal of the American Chemical Society 1990 112:9308-9309 DOI:10.1021/ja00181a037
- Svensson, E. C., Soreghan, B., Paulson, J. C. Organization of the beta-galactoside alpha-2,6-sialyltransferase gene - evidence for the transcriptional regulation of terminal glycosylation Journal of Biological Chemistry 1990 265:20863-20868 PMID:2249992
- Baum, L. G., Paulson, J. C. Sialyloligosaccharides of the respiratory epithelium in the selection of human influenza virus receptor specificity Acta Histochemica Supplement 1990 35-38 PMID:2091044
- Herrler, G., Gross, H. J., Milks, G., Paulson, J. C., Klenk, H. D., Brossmer, R. Use of a sialic acid analogue to analyze the importance of the receptor-destroying enzyme for the interaction of influenza c virus with cells Acta Histochemica Supplement 1990 40:39-41 PMID:1965334
- Hanaoka, K., Pritchett, T. J., Takasaki, S., Kochibe, N., Sabesan, S., Paulson, J. C., Kobata, A. 4-O-acetyl-N-acetylneuraminic acid in the N-linked carbohydrate structures of equine and guinea pig alpha 2-macroglobulins, potent inhibitors of influenza virus infection Journal of Biological Chemistry 1989 264:9842-9849 PMID:2470764
- Lee, E. U., Roth, J., Paulson, J. C. Alteration of terminal glycosylation sequences on n-linked oligosaccharides of chinese-hamster ovary cells by expression of beta-galactoside alpha-2,6-sialyltransferase Journal of Biological Chemistry 1989 264:13848-13855 PMID:2668274
- Pritchett, T. J., Paulson, J. C. Basis for the potent inhibition of influenza-virus infection by equine and guinea-pig alpha-2-macroglobulin Journal of Biological Chemistry 1989 264:9850-9858 PMID:2470765
- Colley, K. J., Lee, E. U., Adler, B., Browne, J. K., Paulson, J. C. Conversion of a golgi-apparatus sialyltransferase to a secretory protein by replacement of the nh2-terminal signal anchor with a signal peptide Journal of Biological Chemistry 1989 264:17619-17622 PMID:2808334
- Paulson, J. C. Glycoproteins - what are the sugar chains for Trends in Biochemical Sciences 1989 14:272-276 DOI:10.1016/0968-0004(89)90062-5 PMID:2672447
- Paulson, J. C., Colley, K. J. Glycosyltransferases - structure, localization, and control of cell type-specific glycosylation Journal of Biological Chemistry 1989 264:17615-17618 PMID:2681181
- Paulson, J. C., Weinstein, J., Schauer, A. Tissue-specific expression of sialyltransferases Journal of Biological Chemistry 1989 264:10931-10934 PMID:2738054
- Gross, H. J., Rose, U., Krause, J. M., Paulson, J. C., Schmid, K., Feeney, R. E., Brossmer, R. Transfer of synthetic sialic-acid analogs to n-linked and o-linked glycoprotein glycans using 4 different mammalian sialytransferases Biochemistry 1989 28:7386-7392 DOI:10.1021/bi00444a036 PMID:2510824
- Ravindranaths, M. H., Paulson, J. C., Irie, R. F. Human-melanoma antigen o-acetylated ganglioside-gd3 is recognized by cancer-antennarius lectin Journal of Biological Chemistry 1988 263:2079-2086 PMID:3339003
- Taatjes, D. J., Roth, J., Weinstein, J., Paulson, J. C. Post-golgi apparatus localization and regional expression of rat intestinal sialyltransferase detected by immunoelectron microscopy with polypeptide epitope-purified antibody Journal of Biological Chemistry 1988 263:6302-6309 PMID:2452161
- Weis, W., Brown, J. H., Cusack, S., Paulson, J. C., Skehel, J. J., Wiley, D. C. Structure of the influenza-virus hemagglutinin complexed with its receptor, sialic-acid Nature 1988 333:426-431 DOI:10.1038/333426a0 PMID:3374584
- Gross, H. J., Bunsch, A., Paulson, J. C., Brossmer, R. Activation and transfer of novel synthetic 9-substituted sialic acids European Journal of Biochemistry 1987 168:595-602 DOI:10.1111/j.1432-1033.1987.tb13458.x PMID:3665935
- Taatjes, D. J., Roth, J., Weinstein, J., Paulson, J. C., Shaper, N. L., Shaper, J. H. Codistribution of galactosyltransferase and sialyltransferase - reorganization of trans golgi-apparatus elements in hepatocytes in intact liver and cell-culture European Journal of Cell Biology 1987 44:187-194 PMID:3121331
- Ravindranath, M. H., Paulson, J. C. O-acetylsialic acid-specific lectin from the crab cancer-anntenarius Methods in Enzymology 1987 138:520-527 PMID:3600345
- Weinstein, J., Lee, E. U., McEntee, K., Lai, P. H., Paulson, J. C. Primary structure of beta-galactoside alpha-2,6-sialyltransferase - conversion of membrane-bound enzyme to soluble forms by cleavage of the nh2-terminal signal anchor Journal of Biological Chemistry 1987 262:17735-17743 PMID:3121604
- Pritchett, T. J., Brossmer, R., Rose, U., Paulson, J. C. Recognition of mono-valent sialosides by influenza-virus h-3 hemagglutinin Virology 1987 160:502-506 DOI:10.1016/0042-6822(87)90026-2 PMID:3660590
- Paulson, J. C., Rogers, G. N. Resialylated erythrocytes for assessment of the specificity of sialyloligosaccharide binding-proteins Methods in Enzymology 1987 138:162-168 PMID:3600320
- Paulson, J. C., Weinstein, J., Ujita, E. L., Riggs, K. J., Lai, P. H. The membrane-binding domain of a rat-liver golgi sialyltransferase Biochemical Society Transactions 1987 15:618-620 PMID:3315771
- Daniels, R. S., Jeffries, S., Yates, P., Schild, G. C., Rogers, G. N., Paulson, J. C., Wharton, S. A., Douglas, A. R., Skehel, J. J., Wiley, D. C. The receptor-binding and membrane-fusion properties of influenza-virus variants selected using anti-hemagglutinin monoclonal-antibodies EMBO Journal 1987 6:1459-1465 PMID:3608984 PMCID:PMC553952
- Sabesan, S., Paulson, J. C. Combined chemical and enzymatic-synthesis of sialyloligosaccharides and characterization by 500-mhz h-1 and c-13 NMR-spectroscopy Journal of the American Chemical Society 1986 108:2068-2080 DOI:10.1021/ja00268a056
- Roth, J., Taatjes, D. J., Weinstein, J., Paulson, J. C., Greenwell, P., Watkins, W. M. Differential subcompartmentation of terminal glycosylation in the golgi-apparatus of intestinal absorptive and goblet cells Journal of Biological Chemistry 1986 261:14307-14312 PMID:3095318
- Rogers, G. N., Herrler, G., Paulson, J. C., Klenk, H. D. Influenza-c virus uses 9-o-acetyl-n-acetylneuraminic acid as a high-affinity receptor determinant for attachment to cells Journal of Biological Chemistry 1986 261:5947-5951 PMID:3700379
- Kelm, S., Shukla, A. K., Paulson, J. C., Schauer, R. Reconstitution of the masking effect of sialic-acid groups on sialidase-treated erythrocytes by the action of sialyltransferases Carbohydrate Research 1986 149:59-64 DOI:10.1016/s0008-6215(00)90369-0 PMID:3089604
- Roth, J., Taatjes, D. J., Lucocq, J. M., Weinstein, J., Paulson, J. C. Demonstration of an extensive tras-tubular network continuous with the golgi-apparatus stack that may function in glycosylation Cell 1985 43:287-295 DOI:10.1016/0092-8674(85)90034-0 PMID:3000603
- Carroll, S. M., Paulson, J. C. Differential infection of receptor-modified host-cells by receptor-specific influenza-viruses Virus Research 1985 3:165-179 DOI:10.1016/0168-1702(85)90006-1 PMID:4060886
- Rogers, G. N., Daniels, R. S., Skehel, J. J., Wiley, D. C., Wang, X. F., Higa, H. H., Paulson, J. C. Host-mediated selection of influenza-virus receptor variants - sialic acid alpha-2,6gal-specific clones of a/duck/ukraine/1/63 revert to sialic acid-alpha-2,3gal-specific wild-type inovo Journal of Biological Chemistry 1985 260:7362-7367 PMID:3997874
- Higa, H. H., Rogers, G. N., Paulson, J. C. Influenza-virus hemagglutinins differentiate between receptor determinants bearing n-acetylneuraminic, n-glycollylneuraminic, and n,o-diacetylneuraminic acids Virology 1985 144:279-282 DOI:10.1016/0042-6822(85)90325-3 PMID:4060591
- Ravindranath, M. H., Higa, H. H., Cooper, E. L., Paulson, J. C. Purification and characterization of an o-acetylsialic acid-specific lectin from a marine crab cancer-antennarius Journal of Biological Chemistry 1985 260:8850-8856 PMID:4019458
- Higa, H. H., Paulson, J. C., Weinstein, J. Sialylation of glycoprotein oligosaccharides with n-acetylneuraminic, n-glycolylneuraminic, and n-o-diacetylneuraminic acids Journal of Biological Chemistry 1985 260:8838-8849 PMID:4019457
- Daniels, R. S., Douglas, A. R., Skehel, J. J., Wiley, D. C., Naeve, C. W., Webster, R. G., Rogers, G. N., Paulson, J. C. Antigenic analyses of influenza-virus hemagglutinins with different receptor-binding specificities Virology 1984 138:174-177 DOI:10.1016/0042-6822(84)90158-2 PMID:6208680
- Paulson, J. C., Weinstein, J., Desouzaesilva, U. Biosynthesis of a disialylated sequence in n-linked oligosaccharides - identification of an n-acetylglucosaminide (alpha-2- 6)-sialyltransferase in golgi-apparatus from rat-liver European Journal of Biochemistry 1984 140:523-530 DOI:10.1111/j.1432-1033.1984.tb08133.x PMID:6547092
- Loomes, L. M., Uemura, K., Childs, R. A., Paulson, J. C., Rogers, G. N., Scudder, P. R., Michalski, J. C., Hounsell, E. F., Taylorrobinson, D., Feizi, T. Erythrocyte receptors for mycoplasma-pneumoniae are sialylated oligosaccharides of ii antigen type Nature 1984 307:560-563 DOI:10.1038/307560a0 PMID:6420710
- Tai, T., Cahan, L. D., Paulson, J. C., Saxton, R. E., Irie, R. F. Human monoclonal-antibody against ganglioside gd2 - use in development of enzyme-linked immunosorbent-assay for the monitoring of anti-gd2 in cancer-patients Journal of the National Cancer Institute 1984 73:627-633 PMID:6206271
- Paulson, J. C., Rogers, G. N., Carroll, S. M., Higa, H. H., Pritchett, T., Milks, G., Sabesan, S. Selection of influenza-virus variants based on sialyloligosaccharide receptor specificity Pure and Applied Chemistry 1984 56:797-805 DOI:10.1351/pac198456070797
- Rogers, G. N., Pritchett, T. J., Lane, J. L., Paulson, J. C. Differential sensitivity of human, avian, and equine influenza-a viruses to a glycoprotein inhibitor of infection - selection of receptor specific variants Virology 1983 131:394-408 DOI:10.1016/0042-6822(83)90507-x PMID:6197808
- Tai, T., Paulson, J. C., Cahan, L. D., Irie, R. F. Ganglioside gm2 as a human-tumor antigen (ofa-i-1) Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1983 80:5392-5396 DOI:10.1073/pnas.80.17.5392 PMID:6193515
- Rogers, G. N., Paulson, J. C. Receptor determinants of human and animal influenza-virus isolates - differences in receptor specificity of the hemagglutinin-h-3 based on species of origin Virology 1983 127:361-373 DOI:10.1016/0042-6822(83)90150-2 PMID:6868370
- Cahan, L. D., Singh, R., Paulson, J. C. Sialyloligosaccharide receptors of binding variants of polyoma-virus Virology 1983 130:281-289 DOI:10.1016/0042-6822(83)90083-1 PMID:6316632
- Rogers, G. N., Paulson, J. C., Daniels, R. S., Skehel, J. J., Wilson, I. A., Wiley, D. C. Single amino-acid substitutions in influenza hemagglutinin change receptor-binding specificity Nature 1983 304:76-78 DOI:10.1038/304076a0 PMID:6191220
- Corfield, A. P., Higa, H., Paulson, J. C., Schauer, R. The specificity of viral and bacterial sialidases for alpha-(2-3)-linked and alpha-(2-6)-linked sialic acids in glycoproteins Biochimica et Biophysica Acta 1983 744:121-126 DOI:10.1016/0167-4838(83)90080-8 PMID:6301560
- Carroll, S. M., Paulson, J. C. Complete metal-ion requirement of influenza-virus n1 neuraminidases Archives of Virology 1982 71:273-277 DOI:10.1007/bf01314879 PMID:6808973
- Paulson, J. C., Weinstein, J., Desouzaesilva, U. Identification of a gal-beta-1 - 3glcnac alpha-2 - 3 sialyltransferase in rat-liver Journal of Biological Chemistry 1982 257:4034-4037 PMID:7068622
- Cahan, L. D., Irie, R. F., Singh, R., Cassidenti, A., Paulson, J. C. Identification of a human neuroectodermal tumor-antigen (ofa-i-2) as ganglioside gd2 Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1982 79:7629-7633 DOI:10.1073/pnas.79.24.7629 PMID:6296843
- Paulson, J. C., Weinstein, J., Dorland, L., Vanhalbeek, H., Vliegenthart, J. F. G. Newcastle-disease virus contains a linkage-specific glycoprotein sialidase - application to the localization of sialic-acid residues in n-linked oligosaccharides of alpha-1 acid glycoprotein Journal of Biological Chemistry 1982 257:2734-2738 PMID:7061446
- Weinstein, J., Desouzaesilva, U., Paulson, J. C. Purification of a gal-beta-1- 4glcnac alpha-2- 6 sialyltransferase and a gal-beta-1- 3(4)glcnac alpha-2- 3 sialyltransferase to homogeneity from rat-liver Journal of Biological Chemistry 1982 257:3835-3844
- Sadler, J. E., Beyer, T. A., Oppenheimer, C. L., Paulson, J. C., Prieels, J. P., Rearick, J. I., Hill, R. L. Purification of mammalian glycosyltransferases Methods in Enzymology 1982 83:458-514 PMID:6808302
- Weinstein, J., Desouzaesilva, U., Paulson, J. C. Sialylation of glycoprotein oligosaccharides n-linked to asparagine - enzymatic characterization of a gal-beta-1- 3(4)glcnac alpha-2- 3 sialyltransferase and a gal-beta-1- 4glcnac alpha-2- 6 sialyltransferase from rat-liver Journal of Biological Chemistry 1982 257:3845-3853
- Berger, E. G., Buddecke, E., Kamerling, J. P., Kobata, A., Paulson, J. C., Vliegenthart, J. F. G. Structure, biosynthesis and functions of glycoprotein glycans Experientia 1982 38:1129-1162 DOI:10.1007/bf01959725 PMID:6754417
- Carroll, S. M., Higa, H. H., Paulson, J. C. Different cell-surface receptor determinants of antigenically similar influenza-virus hemagglutinins Journal of Biological Chemistry 1981 256:8357-8363 PMID:6167577
- Fried, H., Cahan, L. D., Paulson, J. C. Polyoma-virus recognizes specific sialyloligosaccharide receptors on host-cells Virology 1981 109:188-192 DOI:10.1016/0042-6822(81)90485-2 PMID:6258307
- Markwell, M. A. K., Svennerholm, L., Paulson, J. C. Specific gangliosides function as host-cell receptors for sendai virus Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1981 78:5406-5410 DOI:10.1073/pnas.78.9.5406 PMID:6272300
- Cahan, L. D., Paulson, J. C. Polyoma-virus adsorbs to specific sialyloligosaccharide receptors on erythrocytes Virology 1980 103:505-509 DOI:10.1016/0042-6822(80)90208-1 PMID:6247827
- Markwell, M. A. K., Paulson, J. C. Sendai virus utilizes specific sialyloligosaccharides as host-cell receptor determinants Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1980 77:5693-5697 DOI:10.1073/pnas.77.10.5693 PMID:6255459
- Beyer, T. A., Rearick, J. I., Paulson, J. C., Prieels, J. P., Sadler, J. E., Hill, R. L. Biosynthesis of mammalian glycoproteins - glycosylation pathways in the synthesis of the nonreducing terminal sequences Journal of Biological Chemistry 1979 254:2531-2541
- Sodetz, J. M., Paulson, J. C., McKee, P. A. Carbohydrate composition and identification of blood group A, B, and H oligosaccharide structures on human Factor VIII/von Willebrand factor Journal of Biological Chemistry 1979 254:754-760 PMID:315409
- Rearick, J. I., Sadler, J. E., Paulson, J. C., Hill, R. L. Enzymatic characterization of beta-d-galactoside alpha-2- 3 sialytransferase from porcine sub-maxillary gland Journal of Biological Chemistry 1979 254:4444-4451 PMID:438198
- Sadler, J. E., Rearick, J. I., Paulson, J. C., Hill, R. L. Purification to homogeneity of a beta-galactoside alpha-2- 3 sialytransferase and partial-purification of an alpha-n-acetylgalactosaminide alpha-2- 6 sialytransferase from porcine sub-maxillary glands Journal of Biological Chemistry 1979 254:4434-4442 PMID:438196
- Paulson, J. C., Sadler, J. E., Hill, R. L. Restoration of specific myxovirus receptors to asialoerythrocytes by incorporation of sialic-acid with pure sialytransferases Journal of Biological Chemistry 1979 254:2120-2124 PMID:422571
- Sadler, J. E., Paulson, J. C., Hill, R. L. Role of sialic-acid in the expression of human mn blood-group antigens Journal of Biological Chemistry 1979 254:2112-2119 PMID:422570
- Sodetz, J. M., Paulson, J. C., Pizzo, S. V., McKee, P. A. Carbohydrate on human factor viii von willebrand factor - impairment of function by removal of specific galactose residues Journal of Biological Chemistry 1978 253:7202-7206 PMID:100492
- Prieels, J. P., Pizzo, S. V., Glasgow, L. R., Paulson, J. C., Hill, R. L. Hepatic receptor that specifically binds oligosaccharides containing fucosyl alpha1- 3 n-acetylglucosamine linkages Proceedings of the National Academy of Sciences of the United States of America 1978 75:2215-2219 DOI:10.1073/pnas.75.5.2215 PMID:276862
- Vaneldik, L. J., Paulson, J. C., Green, R. W., Smith, R. E. Influence of carbohydrate on antigenicity of envelope glycoprotein of avian-myeloblastosis virus and b77 avian-sarcoma virus Virology 1978 86:193-204 DOI:10.1016/0042-6822(78)90020-x PMID:208246
- Paulson, J. C., Prieels, J. P., Glasgow, L. R., Hill, R. L. Sialyltransferases and fucosyltransferases in biosynthesis of asparaginyl-linked oligosaccharides in glycoproteins - mutually exclusive glycosylation by beta-galactoside -alpha-2- 6-sialyltransferase and n-acetylglucosaminide -alpha-1- 3-fucosyltransferase Journal of Biological Chemistry 1978 253:5617-5624 PMID:27517
- Paulson, J. C., Rearick, J. I., Hill, R. L. Enzymatic properties of beta-d-galactoside alpha-2- 6 sialyltransferase from bovine colostrum Journal of Biological Chemistry 1977 252:2363-2371 PMID:849933
- McClure, W. O., Paulson, J. C. Interaction of colchicine and some related alkaloids with rat-brain tubulin Molecular Pharmacology 1977 13:560-575 PMID:559920
- Paulson, J. C., Beranek, W. E., Hill, R. L. Purification of a sialyltransferase from bovine colostrum by affinity chromatography on cdp-agarose Journal of Biological Chemistry 1977 252:2356-2362 PMID:849932
- Paulson, J. C., Hill, R. L., Tanabe, T., Ashwell, G. Reactivation of asialo-rabbit liver binding-protein by resialylation with beta-d-galactoside alpha2- 6 sialyltransferase Journal of Biological Chemistry 1977 252:8624-8628 PMID:411790
- Glasgow, L. R., Paulson, J. C., Hill, R. L. Systematic purification of 5 glycosidases from streptococcus-(diplococcus)-pneumoniae Journal of Biological Chemistry 1977 252:8615-8623 PMID:21878
- Paulson, J. C., McClure, W. O. Inhibition of axoplasmic-transport by colchicine, podophyllotoxin, and vinblastine - effect on microtubules Annals of the New York Academy of Sciences 1975 253:517-527 DOI:10.1111/j.1749-6632.1975.tb19225.x PMID:50035
- Paulson, J. C., McClure, W. O. Microtubules and axoplasmic-transport - inhibition of transport by podophyllotoxin - interaction with microtubule protein Journal of Cell Biology 1975 67:461-467 DOI:10.1083/jcb.67.2.461 PMID:53233
- Paulson, J. C., McClure, W. O. Lack of correlation between hallucinogenesis and inhibition of axoplasmic-transport Molecular Pharmacology 1974 10:419-424 PMID:4137280
- Paulson, J. C., McClure, W. O. Microtubules and axoplasmic-transport Brain Research 1974 73:333-337 DOI:10.1016/0006-8993(74)91053-1 PMID:4133901
- Paulson, J. C., McClure, W. O. Inhibition of axoplasmic transport by mescaline and other trimethoxyphenylalkylamines Molecular Pharmacology 1973 9:41-50 PMID:4119560
- Paulson, J. C. Adaptation of oxygen flask method for ashing of cellulosic materials Analytical Chemistry 1963 35:1558-1559 DOI:10.1021/ac60203a070
-
thesis