recent publications
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academic article
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Colunga, T., Hayworth, M., Kress, S., Reynolds, D. M., Chen, L., Nazor, K. L., Baur, J., Singh, A. M., Loring, J. F., Metzger, M., Dalton, S.
Human pluripotent stem cell-derived multipotent vascular progenitors of the mesothelium lineage have utility in tissue engineering and repair
Cell Reports
2019
26:2566-2579
DOI:10.1016/j.celrep.2019.02.016
PMID:30840882
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Boland, M. J., Nazor, K. L., Tran, H. T., Szucs, A., Lynch, C. L., Paredes, R., Tassone, F., Sanna, P. P., Hagerman, R. J., Loring, J. F.
Molecular analyses of neurogenic defects in a human pluripotent stem cell model of fragile X syndrome
Brain
2017
140:582-598
DOI:10.1093/brain/aww357
PMID:28137726
- Schork, N. J., Nazor, K. Integrated Genomic Medicine: A Paradigm for Rare Diseases and Beyond Advances in Genetics 2017 97:81-113 DOI:10.1016/bs.adgen.2017.06.001 PMID:28838357
- Cayer, D. M., Nazor, K. L., Schork, N. J. Mission critical: the need for proteomics in the era of next-generation sequencing and precision medicine Human Molecular Genetics 2016 25:R182-R189 DOI:10.1093/hmg/ddw214 PMID:27439388
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Bhutani, K., Nazor, K. L., Williams, R., Tran, H., Dai, H., Dzakula, Z., Cho, E. H., Pang, A. W. C., Rao, M., Cao, H., Schork, N. J., Loring, J. F.
Whole-genome mutational burden analysis of three pluripotency induction methods
Nature Communications
2016
7
DOI:10.1038/ncomms10536
PMID:26892726
PMCID:PMC4762882
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Zdravkovic, T., Nazor, K. L., Larocque, N., Gormley, M., Donne, M., Hunkapillar, N., Giritharan, G., Bernstein, H. S., Wei, G., Hebrok, M., Zeng, X., Genbacev, O., et al.
Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification
Development
2015
142:4010-4025
DOI:10.1242/dev.122846
PMID:26483210
PMCID:PMC4712832
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Rivera-Mulia, J. C., Buckley, Q., Sasaki, T., Zimmerman, J., Didier, R. A., Nazor, K., Loring, J. F., Lian, Z., Weissman, S., Robins, A. J., Schulz, T. C., Menendez, L., et al.
Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells
Genome Research
2015
25:1091-1103
DOI:10.1101/gr.187989.114
PMID:26055160
PMCID:PMC4509994
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Garitaonandia, I., Amir, H., Boscolo, F. S., Wambua, G. K., Schultheisz, H. L., Sabatini, K., Morey, R., Waltz, S., Wang, Y. C., Tran, H., Leonardo, T. R., Nazor, K., et al.
Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions
PLoS One
2015
10:e0118307
DOI:10.1371/journal.pone.0118307
PMID:25714340
PMCID:PMC4340884
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Gomez, S., Castellano, G., Mayol, G., Sunol, M., Queiros, A., Bibikova, M., Nazor, K. L., Loring, J. F., Lemos, I., Rodriguez, E., De Torres, C., Mora, J., et al.
DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights
Epigenomics
2015
7:1137-1153
DOI:10.2217/epi.15.49
PMID:26067621
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Nazor, K. L., Boland, M. J., Bibikova, M., Klotzle, B., Yu, M., Glenn-Pratola, V. L., Schell, J. P., Coleman, R. L., Cabral-da-Silva, M. C., Schmidt, U., Peterson, S. E., He, C., et al.
Application of a low cost array-based technique - TAB-Array - for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells
Genomics
2014
104:358-367
DOI:10.1016/j.ygeno.2014.08.014
PMID:25179373
PMCID:PMC4342188
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Soragni, E., Miao, W., Iudicello, M., Jacoby, D., De Mercanti, S., Clerico, M., Longo, F., Piga, A., Ku, S., Campau, E., Du, J., Penalver, P., et al.
Epigenetic therapy for Friedreich ataxia
Annals of Neurology
2014
76:489-508
DOI:10.1002/ana.24260
PMID:25159818
PMCID:PMC4361037
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Boland, M. J., Nazor, K. L., Loring, J. F.
Epigenetic regulation of pluripotency and differentiation
Circulation Research
2014
115:311-324
DOI:10.1161/circresaha.115.301517
PMID:24989490
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Liao, X., Xue, H., Wang, Y. C., Nazor, K. L., Guo, S., Trivedi, N., Peterson, S. E., Liu, Y., Loring, J. F., Laurent, L. C.
Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions
Journal of Cell Science
2013
126:3848-3861
DOI:10.1242/jcs.123570
PMID:23813959
PMCID:PMC3757328
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Li, Y., Moretto-Zita, M., Soncin, F., Wakeland, A., Wolfe, L., Leon-Garcia, S., Pandian, R., Pizzo, D., Cui, L., Nazor, K., Loring, J. F., Crum, C. P., et al.
BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state
Development
2013
140:3965-3976
DOI:10.1242/dev.092155
PMID:24004950
PMCID:PMC3775414
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Boland, M. J., Hazen, J. L., Nazor, K. L., Rodriguez, A. R., Martin, G., Kupriyanov, S., Baldwin, K. K.
Generation of mice derived from induced pluripotent stem cells
Journal of Visualized Experiments : JoVE
2012
e4003
DOI:10.3791/4003
PMID:23222420
PMCID:PMC3565852
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Nazor, K. L., Loring, J. F., Laurent, L. C.
Equally potent? Does cellular reprogramming justify the abandonment of human embryonic stem cells?
EMBO Reports
2012
13:890-894
DOI:10.1038/embor.2012.134
PMID:22986548
PMCID:PMC3463969
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Nazor, K. L., Altun, G., Lynch, C., Tran, H., Harness, J. V., Slavin, I., Garitaonandia, I., Muller, F. J., Wang, Y. C., Boscolo, F. S., Fakunle, E., Dumevska, B., et al.
Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives
Cell Stem Cell
2012
10:620-634
DOI:10.1016/j.stem.2012.02.013
PMID:22560082
PMCID:PMC3348513
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Israel, M. A., Yuan, S. H., Bardy, C., Reyna, S. M., Mu, Y., Herrera, C., Hefferan, M. P., Van Gorp, S., Nazor, K. L., Boscolo, F. S., Carson, C. T., Laurent, L. C., et al.
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells
Nature
2012
482:216-220
DOI:10.1038/nature10821
PMID:22278060
PMCID:PMC3338985
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Wang, Y. C., Nakagawa, M., Garitaonandia, I., Slavin, I., Altun, G., Lacharite, R. M., Nazor, K. L., Tran, H. T., Lynch, C. L., Leonardo, T. R., Liu, Y., Peterson, S. E., et al.
Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis
Cell Research
2011
21:1551-1563
DOI:10.1038/cr.2011.148
PMID:21894191
PMCID:PMC3364725
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Boland, M. J., Hazen, J. L., Nazor, K. L., Rodriguez, A. R., Gifford, W., Martin, G., Kupriyanov, S., Baldwin, K. K.
Adult mice generated from induced pluripotent stem cells
Nature
2009
461:91-94
DOI:10.1038/nature08310
PMID:19672243
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chapter
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Nazor, K. L., Thiagarajan, R. D., Laurent, L. C.
Analysis of genome-wide gene expression data from microarrays and sequencing
Human Stem Cell Manual (Second Edition).
271-291.
2012
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Bibikova, M., Nazor, K. L., Altun, G., Laurent, L. C.
Epigenetics: DNA Methylation
Human Stem Cell Manual (Second Edition).
325-336.
2012
DOI:10.1016/B978-0-12-385473-5.00020-5
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