recent publications
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academic article
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Colunga, T., Hayworth, M., Kress, S., Reynolds, D. M., Chen, L., Nazor, K. L., Baur, J., Singh, A. M., Loring, J. F., Metzger, M., Dalton, S. Human pluripotent stem cell-derived multipotent vascular progenitors of the mesothelium lineage have utility in tissue engineering and repair Cell Reports 2019 26:2566-2579 DOI:10.1016/j.celrep.2019.02.016 PMID:30840882
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Boland, M. J., Nazor, K. L., Tran, H. T., Szucs, A., Lynch, C. L., Paredes, R., Tassone, F., Sanna, P. P., Hagerman, R. J., Loring, J. F. Molecular analyses of neurogenic defects in a human pluripotent stem cell model of fragile X syndrome Brain 2017 140:582-598 DOI:10.1093/brain/aww357 PMID:28137726
- Schork, N. J., Nazor, K. Integrated Genomic Medicine: A Paradigm for Rare Diseases and Beyond Advances in Genetics 2017 97:81-113 DOI:10.1016/bs.adgen.2017.06.001 PMID:28838357
- Cayer, D. M., Nazor, K. L., Schork, N. J. Mission critical: the need for proteomics in the era of next-generation sequencing and precision medicine Human Molecular Genetics 2016 25:R182-R189 DOI:10.1093/hmg/ddw214 PMID:27439388
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Bhutani, K., Nazor, K. L., Williams, R., Tran, H., Dai, H., Dzakula, Z., Cho, E. H., Pang, A. W. C., Rao, M., Cao, H., Schork, N. J., Loring, J. F. Whole-genome mutational burden analysis of three pluripotency induction methods Nature Communications 2016 7 DOI:10.1038/ncomms10536 PMID:26892726 PMCID:PMC4762882
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Zdravkovic, T., Nazor, K. L., Larocque, N., Gormley, M., Donne, M., Hunkapillar, N., Giritharan, G., Bernstein, H. S., Wei, G., Hebrok, M., Zeng, X., Genbacev, O., et al. Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification Development 2015 142:4010-4025 DOI:10.1242/dev.122846 PMID:26483210 PMCID:PMC4712832
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Rivera-Mulia, J. C., Buckley, Q., Sasaki, T., Zimmerman, J., Didier, R. A., Nazor, K., Loring, J. F., Lian, Z., Weissman, S., Robins, A. J., Schulz, T. C., Menendez, L., et al. Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells Genome Research 2015 25:1091-1103 DOI:10.1101/gr.187989.114 PMID:26055160 PMCID:PMC4509994
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Garitaonandia, I., Amir, H., Boscolo, F. S., Wambua, G. K., Schultheisz, H. L., Sabatini, K., Morey, R., Waltz, S., Wang, Y. C., Tran, H., Leonardo, T. R., Nazor, K., et al. Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions PLoS One 2015 10:e0118307 DOI:10.1371/journal.pone.0118307 PMID:25714340 PMCID:PMC4340884
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Gomez, S., Castellano, G., Mayol, G., Sunol, M., Queiros, A., Bibikova, M., Nazor, K. L., Loring, J. F., Lemos, I., Rodriguez, E., De Torres, C., Mora, J., et al. DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights Epigenomics 2015 7:1137-1153 DOI:10.2217/epi.15.49 PMID:26067621
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Nazor, K. L., Boland, M. J., Bibikova, M., Klotzle, B., Yu, M., Glenn-Pratola, V. L., Schell, J. P., Coleman, R. L., Cabral-da-Silva, M. C., Schmidt, U., Peterson, S. E., He, C., et al. Application of a low cost array-based technique - TAB-Array - for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells Genomics 2014 104:358-367 DOI:10.1016/j.ygeno.2014.08.014 PMID:25179373 PMCID:PMC4342188
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Soragni, E., Miao, W., Iudicello, M., Jacoby, D., De Mercanti, S., Clerico, M., Longo, F., Piga, A., Ku, S., Campau, E., Du, J., Penalver, P., et al. Epigenetic therapy for Friedreich ataxia Annals of Neurology 2014 76:489-508 DOI:10.1002/ana.24260 PMID:25159818 PMCID:PMC4361037
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Boland, M. J., Nazor, K. L., Loring, J. F. Epigenetic regulation of pluripotency and differentiation Circulation Research 2014 115:311-324 DOI:10.1161/circresaha.115.301517 PMID:24989490
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Liao, X., Xue, H., Wang, Y. C., Nazor, K. L., Guo, S., Trivedi, N., Peterson, S. E., Liu, Y., Loring, J. F., Laurent, L. C. Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions Journal of Cell Science 2013 126:3848-3861 DOI:10.1242/jcs.123570 PMID:23813959 PMCID:PMC3757328
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Li, Y., Moretto-Zita, M., Soncin, F., Wakeland, A., Wolfe, L., Leon-Garcia, S., Pandian, R., Pizzo, D., Cui, L., Nazor, K., Loring, J. F., Crum, C. P., et al. BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state Development 2013 140:3965-3976 DOI:10.1242/dev.092155 PMID:24004950 PMCID:PMC3775414
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Boland, M. J., Hazen, J. L., Nazor, K. L., Rodriguez, A. R., Martin, G., Kupriyanov, S., Baldwin, K. K. Generation of mice derived from induced pluripotent stem cells Journal of Visualized Experiments : JoVE 2012 e4003 DOI:10.3791/4003 PMID:23222420 PMCID:PMC3565852
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Nazor, K. L., Loring, J. F., Laurent, L. C. Equally potent? Does cellular reprogramming justify the abandonment of human embryonic stem cells? EMBO Reports 2012 13:890-894 DOI:10.1038/embor.2012.134 PMID:22986548 PMCID:PMC3463969
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Nazor, K. L., Altun, G., Lynch, C., Tran, H., Harness, J. V., Slavin, I., Garitaonandia, I., Muller, F. J., Wang, Y. C., Boscolo, F. S., Fakunle, E., Dumevska, B., et al. Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives Cell Stem Cell 2012 10:620-634 DOI:10.1016/j.stem.2012.02.013 PMID:22560082 PMCID:PMC3348513
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Israel, M. A., Yuan, S. H., Bardy, C., Reyna, S. M., Mu, Y., Herrera, C., Hefferan, M. P., Van Gorp, S., Nazor, K. L., Boscolo, F. S., Carson, C. T., Laurent, L. C., et al. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells Nature 2012 482:216-220 DOI:10.1038/nature10821 PMID:22278060 PMCID:PMC3338985
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Wang, Y. C., Nakagawa, M., Garitaonandia, I., Slavin, I., Altun, G., Lacharite, R. M., Nazor, K. L., Tran, H. T., Lynch, C. L., Leonardo, T. R., Liu, Y., Peterson, S. E., et al. Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis Cell Research 2011 21:1551-1563 DOI:10.1038/cr.2011.148 PMID:21894191 PMCID:PMC3364725
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Boland, M. J., Hazen, J. L., Nazor, K. L., Rodriguez, A. R., Gifford, W., Martin, G., Kupriyanov, S., Baldwin, K. K. Adult mice generated from induced pluripotent stem cells Nature 2009 461:91-94 DOI:10.1038/nature08310 PMID:19672243
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chapter
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Nazor, K. L., Thiagarajan, R. D., Laurent, L. C. Analysis of genome-wide gene expression data from microarrays and sequencing Human Stem Cell Manual (Second Edition). 271-291. 2012
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Bibikova, M., Nazor, K. L., Altun, G., Laurent, L. C. Epigenetics: DNA Methylation Human Stem Cell Manual (Second Edition). 325-336. 2012 DOI:10.1016/B978-0-12-385473-5.00020-5
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