recent publications
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academic article
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Lin, C. W., Zheng, T. Q., Grande, G., Nanna, A. R., Rader, C., Lerner, R. A. A new immunochemical strategy for triple-negative breast cancer therapy Scientific Reports 2021 11 DOI:10.1038/s41598-021-94230-4 PMID:34290315 PMCID:PMC8295383
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Nanna, A. R., Kel'in, A. V., Theile, C., Pierson, J. M., Voo, Z. X., Garg, A., Nair, J. K., Maier, M. A., Fitzgerald, K., Rader, C. Generation and validation of structurally defined antibody-siRNA conjugates Nucleic Acids Research 2020 48:5281-5293 DOI:10.1093/nar/gkaa286 PMID:32347936 PMCID:PMC7261152
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Hwang, D.*, Nilchan, N.*, Nanna, A. R., Li, X., Cameron, M. D., Roush, W. R., Park, H., Rader, C. Site-selective antibody functionalization via orthogonally reactive arginine and lysine residues Cell Chemical Biology 2019 26:1229-1239 DOI:10.1016/j.chembiol.2019.05.010 PMID:31231031 PMCID:PMC6754284 (* = equal contribution)
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Nanna, A. R., Li, X., Walseng, E., Pedzisa, L., Goydel, R. S., Hymel, D., Burke, T. R., Roush, W. R., Rader, C. Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates Nature Communications 2017 8 DOI:10.1038/s41467-017-01257-1 PMID:29062027 PMCID:PMC5653646
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Li, X., Nelson, C. G., Nair, R. R., Hazlehurst, L., Moroni, T., Martinez-Acedo, P., Nanna, A. R., Hymel, D., Burke, T. R., Rader, C. Stable and potent selenomab-drug conjugates Cell Chemical Biology 2017 24:433-442 DOI:10.1016/j.chembiol.2017.02.012 PMID:28330604 PMCID:PMC5400723
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Walseng, E., Nelson, C. G., Qi, J., Nanna, A. R., Roush, W. R., Goswami, R. K., Sinha, S. C., Burke Jr., T. R., Rader, C. Chemically programmed bispecific antibodies in diabody format Journal of Biological Chemistry 2016 291:19661-19673 DOI:10.1074/jbc.M116.745588 PMID:27445334 PMCID:PMC5016699
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chapter
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Nanna, A. R., Roush, W. R., Rader, C. Chemical assembly of antibody-drug conjugates Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins. 1-28. 2017
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