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Nanna, Alex
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Nanna, Alex

Graduate Student
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Positions

  • 2015 Visiting Scientist, National Cancer Institute , National Institutes of Health
  • 2012 Undergraduate Research Fellow, Baran Laboratory, Scripps Research
  • 2011 - 2012 Undergraduate Researcher with Professor Andrew N. French, Albion College
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Publications

recent publications
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  • academic article

    • degree-related publication Lin, C. W., Zheng, T. Q., Grande, G., Nanna, A. R., Rader, C., Lerner, R. A. A new immunochemical strategy for triple-negative breast cancer therapy Scientific Reports  2021 11  DOI:10.1038/s41598-021-94230-4  PMID:34290315  PMCID:PMC8295383
    • degree-related publication Nanna, A. R., Kel'in, A. V., Theile, C., Pierson, J. M., Voo, Z. X., Garg, A., Nair, J. K., Maier, M. A., Fitzgerald, K., Rader, C. Generation and validation of structurally defined antibody-siRNA conjugates Nucleic Acids Research  2020 48:5281-5293  DOI:10.1093/nar/gkaa286  PMID:32347936  PMCID:PMC7261152
    • degree-related publication Hwang, D.*, Nilchan, N.*, Nanna, A. R., Li, X., Cameron, M. D., Roush, W. R., Park, H., Rader, C. Site-selective antibody functionalization via orthogonally reactive arginine and lysine residues Cell Chemical Biology  2019 26:1229-1239  DOI:10.1016/j.chembiol.2019.05.010  PMID:31231031  PMCID:PMC6754284 (* = equal contribution)
    • degree-related publication Nanna, A. R., Li, X., Walseng, E., Pedzisa, L., Goydel, R. S., Hymel, D., Burke, T. R., Roush, W. R., Rader, C. Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates Nature Communications  2017 8  DOI:10.1038/s41467-017-01257-1  PMID:29062027  PMCID:PMC5653646
    • degree-related publication Li, X., Nelson, C. G., Nair, R. R., Hazlehurst, L., Moroni, T., Martinez-Acedo, P., Nanna, A. R., Hymel, D., Burke, T. R., Rader, C. Stable and potent selenomab-drug conjugates Cell Chemical Biology  2017 24:433-442  DOI:10.1016/j.chembiol.2017.02.012  PMID:28330604  PMCID:PMC5400723
    • degree-related publication Walseng, E., Nelson, C. G., Qi, J., Nanna, A. R., Roush, W. R., Goswami, R. K., Sinha, S. C., Burke Jr., T. R., Rader, C. Chemically programmed bispecific antibodies in diabody format Journal of Biological Chemistry  2016 291:19661-19673  DOI:10.1074/jbc.M116.745588  PMID:27445334  PMCID:PMC5016699
  • chapter

    • degree-related publication Nanna, A. R., Roush, W. R., Rader, C. Chemical assembly of antibody-drug conjugates Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins. 1-28. 2017
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Background

education and training

  • Ph.D. in Chemistry, Scripps Research 2013 - 2018
  • B.S. in Chemistry, Albion College , Summa Cum Laude 2009 - 2013

advisee of

  • graduate advising relationship

    • Rader, Christoph, Ph.D.  candidacy, 2014 - 2018
    • Roush, William, Ph.D.  candidacy, 2014 - 2018
  • postdoc or fellow advising relationship

    • Rader, Christoph, Ph.D.  candidacy, 2018 - 2019
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Contact

full name

  • Alex Richard Nanna

geographic location

  • Scripps Florida 

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