recent publications
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academic article
- Grevengoed, T. J., Trammell, S. A. J., McKinney, M. K., Petersen, N., Cardone, R. L., Svenningsen, J. S., Ogasawara, D., Nexoe-Larsen, C. C., Knop, F. K., Schwartz, T. W., Kibbey, R. G., Cravatt, B. F., et al. N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis Proceedings of the National Academy of Sciences of the United States of America 2019 116:24770-24778 DOI:10.1073/pnas.1916288116 PMID:31740614 PMCID:PMC6900532
- Kaczocha, M., Lin, Q. Q., Nelson, L. D., McKinney, M. K., Cravatt, B. F., London, E., Deutsch, D. G. Anandamide externally added to lipid vesicles containing-trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion ACS Chemical Neuroscience 2012 3:364-368 DOI:10.1021/cn300001w PMID:22860204 PMCID:PMC3382455
- Saario, S. M., McKinney, M. K., Speers, A. E., Wang, C., Cravatt, B. F. Clickable, photoreactive inhibitors to probe the active site microenvironment of fatty acid amide hydrolase Chemical Science 2012 3:77-83 DOI:10.1039/c1sc00336d PMID:22737400 PMCID:PMC3378062
- Thors, L., Burston, J. J., Alter, B. J., McKinney, M. K., Cravatt, B. F., Ross, R. A., Pertwee, R. G., Gereau, R. W., Wiley, J. L., Fowler, C. J. Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase British Journal of Pharmacology 2010 160:549-560 DOI:10.1111/j.1476-5381.2010.00716.x PMID:20590565 PMCID:PMC2931556
- Freigang, S., Zadorozhny, V., McKinney, M. K., Krebs, P., Herro, R., Pawlak, J., Kain, L., Schrantz, N., Masuda, K., Liu, Y., Savage, P. B., Bendelac, A., et al. Fatty acid amide hydrolase shapes NKT cell responses by influencing the serum transport of lipid antigen in mice Journal of Clinical Investigation 2010 120:1873-1884 DOI:10.1172/jci40451 PMID:20484813 PMCID:PMC2877940
- Ahn, K., Johnson, D. S., Mileni, M., Beidler, D., Long, J. Z., McKinney, M. K., Weerapana, E., Sadagopan, N., Liimatta, M., Smith, S. E., Lazerwith, S., Stiff, C., et al. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain Chemistry & Biology 2009 16:411-420 DOI:10.1016/j.chembiol.2009.02.013 PMID:19389627 PMCID:PMC2692831
- Ahn, K., McKinney, M. K., Cravatt, B. F. Enzymatic pathways that regulate endocannabinoid signaling in the nervous system Chemical Reviews 2008 108:1687-1707 DOI:10.1021/cr0782067 PMID:18429637 PMCID:PMC3150828
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Saghatelian, A., McKinney, M. K., Bandell, M., Patapoutian, A., Cravatt, B. F.
A FAAH-regulated class of N-acyl taurines that activates TRP ion channels
Biochemistry
2006
45:9007-9015
DOI:10.1021/bi0608008
PMID:16866345
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Wei, B. Q. Q., Mikkelsen, T. S., McKinney, M. K., Lander, E. S., Cravatt, B. F.
A second fatty acid amide hydrolase with variable distribution among placental mammals
Journal of Biological Chemistry
2006
281:36569-36578
DOI:10.1074/jbc.M606646200
PMID:17015445
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McKinney, M. K., Cravatt, B. F.
Structure-based design of a FAAH variant that discriminates between the N-acyl ethanolamine and taurine families of signaling lipids
Biochemistry
2006
45:9016-9022
DOI:10.1021/bi0608010
PMID:16866346
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McKinney, M. K., Cravatt, B. F.
Structure and function of fatty acid amide hydrolase
Annual Review of Biochemistry
2005
74:411-432
DOI:10.1146/annurev.biochem.74.082803.133450
PMID:15952893
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McKinney, M. K., Cravatt, B. F.
Evidence for distinct roles in catalysis for residues of the serine-serine-lysine catalytic triad of fatty acid amide hydrolase
Journal of Biological Chemistry
2003
278:37393-37399
DOI:10.1074/jbc.M303922200
PMID:12734197