recent publications
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academic article
- Danovitch, G. M., Bunnapradist, S., Cohen, D., Hariharan, S., McKay, D., Ratner, L., Stegall, M. D., Steiner, R. W., Stock, P. G., Vincenti, F. Tests for the noninvasive diagnosis of kidney transplant rejection should be evaluated by kidney transplant programs American Journal of Transplantation 2021 DOI:10.1111/ajt.16711 PMID:34080294
- Kasimsetty, S., Hawkes, A., DeWolf, S. E., Welch, A., McKay, D. B. Blockade of T cell activation induced by the simultaneous absence of Nod1 and Nod2 is bypassed by TLR2 signals Transplant Immunology 2020 65 DOI:10.1016/j.trim.2020.101348 PMID:33706865
- Kasimsetty, S. G., Hawkes, A., Barekatain, K., Soo, E., Welch, A. K., McKay, D. B. TLR2 and NODs1 and 2 cooperate in inflammatory responses associated with renal ischemia reperfusion injury Transplant Immunology 2020 58 DOI:10.1016/j.trim.2019.101260 PMID:31760144 PMCID:PMC7041897
- Soo, E., Welch, A., Marsh, C., McKay, D. B. Molecular strategies used by hibernators: Potential therapeutic directions for ischemia reperfusion injury and preservation of human donor organs Transplantation Reviews 2020 34 DOI:10.1016/j.trre.2019.100512 PMID:31648853
- Soo, E., Marsh, C., Steiner, R., Stocks, L., McKay, D. B. Optimizing organs for transplantation; advancements in perfusion and preservation methods Transplantation Reviews 2020 34 DOI:10.1016/j.trre.2019.100514 PMID:31645271 PMCID:PMC6905200
- Kasimsetty, S. G., Shigeoka, A. A., Scheinok, A. A., Gavin, A. L., Ulevitch, R. J., McKay, D. B. Lack of both nucleotide-binding oligomerization domain-containing proteins 1 and 2 primes T cells for activation-induced cell death Journal of Immunology 2017 199:1196-1205 DOI:10.4049/jimmunol.1600667 PMID:28652394
- Rutschmann, S., Crozat, K., Li, X., Du, X., Hanselman, J. C., Shigeoka, A. A., Brandl, K., Popkin, D. L., McKay, D. B., Xia, Y., Moresco, E. M. Y., Beutler, B. Hypopigmentation and maternal-zygotic embryonic lethality caused by a hypomorphic mbtps1 mutation in mice G3-Genes Genomes Genetics 2012 2:499-504 DOI:10.1534/g3.112.002196 PMID:22540041 PMCID:PMC3337478
- McKay, D. B. The role of innate immunity in donor organ procurement Seminars in Immunopathology 2011 33:169-184 DOI:10.1007/s00281-011-0254-z PMID:21424913
- McKay, D. B. Intracellular pattern recognition receptors and renal ischemia Critical Reviews in Immunology 2011 31:297-306 DOI:10.1615/CritRevImmunol.v31.i4.20 PMID:21899512
- Josephson, M. A., McKay, D. B. Pregnancy and kidney transplantation Seminars in Nephrology 2011 31:100-110 DOI:10.1016/j.semnephrol.2010.10.009 PMID:21266268
- Shigeoka, A. A., Mueller, J. L., Kambo, A., Mathison, J. C., King, A. J., Hall, W. F., Correia, J. D. S., Ulevitch, R. J., Hoffman, H. M., McKay, D. B. An inflammasome-independent role for epithelial-expressed nlrp3 in renal ischemia-reperfusion injury Journal of Immunology 2010 185:6277-6285 DOI:10.4049/jimmunol.1002330 PMID:20962258 PMCID:PMC3020135
- McKay, D. B., Josephson, M. Pregnancy in renal transplant recipients Dialysis & Transplantation 2010 39:472-475 DOI:10.1002/dat.20511
- Josephson, M. A., McKay, D. B. Pregnancy in the renal transplant recipient Obstetrics and Gynecology Clinics of North America 2010 37:211-222 DOI:10.1016/j.ogc.2010.02.008 PMID:20685549
- Shigeoka, A. A., Kambo, A., Mathison, J. C., King, A. J., Hall, W. F., da Silva Correia, J., Ulevitch, R. J., McKay, D. B. Nod1 and nod2 are expressed in human and murine renal tubular epithelial cells and participate in renal ischemia reperfusion injury Journal of Immunology 2010 184:2297-2304 DOI:10.4049/jimmunol.0903065 PMID:20124104 PMCID:PMC3020136
- Engebretsen, L., Steffen, K., Bahr, R., Broderick, C., Dvorak, J., Janarv, P. M., Johnson, A., Leglise, M., Mamisch, T. C., McKay, D., Micheli, L., Schamasch, P., et al. The international olympic committee consensus statement on age determination in high-level young athletes British Journal of Sports Medicine 2010 44:476-484 DOI:10.1136/bjsm.2010.073122 PMID:20519254
- Fine, R. N., Becker, Y., De Geest, S., Eisen, H., Ettenger, R., Evans, R., Rudow, D. L., McKay, D., Neu, A., Nevins, T., Reyes, J., Wray, J., et al. Nonadherence consensus conference summary report American Journal of Transplantation 2009 9:35-41 DOI:10.1111/j.1600-6143.2008.02495.x PMID:19133930
- Mills, R. E., Taylor, K. R., Podshivalova, K., McKay, D. B., Jameson, J. M. Defects in skin γδ T cell function contribute to delayed wound repair in rapamycin-treated mice Journal of Immunology 2008 181:3974-3983 PMID:18768852 PMCID:PMC2547144
- McKay, D., Potter, S. R., Behrend, T., Stella, F., Steinberg, S. Patients seeking alternatives to the long waiting list: A reality faced by transplant physicians Progress in Transplantation 2008 18:203-207 PMID:18831487
- McKay, D. B., Josephson, M. A. Pregnancy after kidney transplantation Clinical Journal of the American Society of Nephrology 2008 3:S117-S125 DOI:10.2215/cjn.02980707 PMID:18308999 PMCID:PMC3152271
- Shigeoka, A. A., Holscher, T. D., King, A. J., Hallt, F. W., Kiosses, W. B., Tobias, P. S., Mackman, N., McKay, D. B. Tlr2 is constitutively expressed within the kidney and participates in ischemic renal injury through both myd88-dependent and -independent pathways Journal of Immunology 2007 178:6252-6258 PMID:17475853
- Josephson, M. A., McKay, D. B. Considerations in the medical management of pregnancy in transplant recipients Advances in Chronic Kidney Disease 2007 14:156-167 DOI:10.1053/j.ackd.2007.01.006 PMID:17395118
- Zambricki, E., Zal, T., Yachi, P., Shigeoka, A., Sprent, J., Gascoigne, N., McKay, D. In vivo anergized T cells form altered immunological synapses in vitro American Journal of Transplantation 2006 6:2572-2579 DOI:10.1111/j.1600-6143.2006.01517.x PMID:16952297
- McKay, D., Shigeoka, A., Rubinstein, M., Surh, C., Sprent, J. Simultaneous deletion of myd88 and trif delays major histocompatibility and minor antigen mismatch allograft rejection European Journal of Immunology 2006 36:1994-2002 DOI:10.1002/eji.200636249 PMID:16874736
- McKay, D. B., Josephson, M. A. Medical progress - pregnancy in recipients of solid organs - effects on mother and child New England Journal of Medicine 2006 354:1281-1293 DOI:10.1056/NEJMra050431 PMID:16554530
- Zambricki, E., Shigeoka, A., Kishimoto, H., Sprent, J., Burakoff, S., Carpenter, C., Milford, E., McKay, D. Signaling t-cell survival and death by il-2 and il-15 American Journal of Transplantation 2005 5:2623-2631 DOI:10.1111/j.1600-6143.2005.01075.x PMID:16212621
- Rubel, J. R., Milford, E. L., McKay, D. B., Jarcho, J. A. Renal insufficiency and end-stage renal disease in the heart transplant population Journal of Heart and Lung Transplantation 2004 23:289-300 DOI:10.1016/s1053-2498(03)00191-8 PMID:15019638
- Kwon, A. R., Kessler, B. M., Overkleeft, H. S., McKay, D. B. Structure and reactivity of an asymmetric complex between hslv and i-domain deleted hslu, a prokaryotic homolog of the eukaryotic proteasome Journal of Molecular Biology 2003 330:185-195 DOI:10.1016/s0022-2836(03)00580-1 PMID:12823960
- Sousa, M. C., Kessler, B. M., Overkleeft, H. S., McKay, D. B. Crystal structure of hsiuv complexed with a vinyl sulfone inhibitor: Corroboration of a proposed mechanism of allosteric activation of hsiv by hsiu Journal of Molecular Biology 2002 318:779-785 DOI:10.1016/s0022-2836(02)00145-6 PMID:12054822
- Halamay, K. E., Kirkman, R. L., Sun, L. H., Yamada, A., Fragoso, R. C., Shimizu, K., Mitchell, R. N., McKay, D. B. Cd8 t cells are sufficient to mediate allorecognition and allograft rejection Cellular Immunology 2002 216:6-14 DOI:10.1016/s0008-8749(02)00530-0 PMID:12381345
- Tkaczuk, J., Yu, C. L., Baksh, S., Milford, E. L., Carpenter, C. B., Burakoff, S. J., McKay, D. B. Effect of anti-il-2r alpha antibody on il-2-induced jak/stat signaling American Journal of Transplantation 2002 2:31-40 DOI:10.1034/j.1600-6143.2002.020107.x PMID:12095053
- Wedekind, J. E., Trame, C. B., Dorywalska, M., Koehl, P., Raschke, T. M., McKee, M., FitzGerald, D., Collier, R. J., McKay, D. B. Refined crystallographic structure of pseudomonas aeruginosa exotoxin a and its implications for the molecular mechanism of toxicity Journal of Molecular Biology 2001 314:823-837 DOI:10.1006/jmbi.2001.5195 PMID:11734000
- Tkaczuk, J., Milford, E., Yu, C., Baksh, S., Carpenter, C., Burakoff, S., McKay, D. Intracellular signaling consequences of anti-il-2r alpha blockade by daclizumab Transplantation Proceedings 2001 33:212-213 DOI:10.1016/s0041-1345(00)01978-3 PMID:11266783
- Sousa, M. C., Trame, C. B., Tsuruta, H., Wilbanks, S. M., Reddy, V. S., McKay, D. B. Crystal and solution structures of an HslUV protease-chaperone complex Cell 2000 103:633-643 DOI:10.1016/s0092-8674(00)00166-5 PMID:11106733
- Tran, H. T. B., Acharya, M. K., McKay, D. B., Sayegh, M. H., Carpenter, C. B., Auchincloss, H., Kirkman, R. L., Milford, E. L. Avoidance of cyclosporine in renal transplantation: Effects of daclizumab, mycophenolate mofetil, and steroids Journal of the American Society of Nephrology 2000 11:1903-1909 PMID:11004222
- McKay, D. B., Irie, H. Y., Hollander, G., Ferrara, Jlmf, Strom, T. B., Li, Y. S., Burakoff, S. J. Antigen-induced unresponsiveness results in altered t cell signaling Journal of Immunology 1999 163:6455-6461 PMID:10586036
- McKay, D. B., Milford, E. L., Carpenter, C. B., Kartashov, A. I., Schoen, F. J., Loh, E., Aranki, S. F., Couper, G. S., Mudge, G. H. T-cell activation in cardiac transplant recipients Transplantation 1994 58:241-245 PMID:8042242
- McKay, D. B., Vazquez, M. A., Redline, R. W., Lu, C. Y. Macrophage functions are regulated by murine decidual and tumor extracellular matrices Journal of Clinical Investigation 1992 89:134-142 DOI:10.1172/jci115553 PMID:1729266
- Kirkman, R. L., Shapiro, M. E., Carpenter, C. B., McKay, D. B., Milford, E. L., Ramos, E. L., Tilney, N. L., Waldmann, T. A., Zimmerman, C. E., Strom, T. B. A randomized prospective trial of anti-Tac monoclonal antibody in human renal transplantation Transplantation Proceedings 1991 23:1066-1067 PMID:1989150
- Kirkman, R. L., Shapiro, M. E., Carpenter, C. B., McKay, D. B., Milford, E. L., Ramos, E. L., Tilney, N. L., Waldmann, T. A., Zimmerman, C. E., Strom, T. B. A randomized prospective trial of anti-Tac monoclonal antibody in human renal transplantation Transplantation 1991 51:107-113 DOI:10.1097/00007890-199101000-00016 PMID:1846250
- Redline, R. W., McKay, D. B., Vazquez, M. A., Papaioannou, V. E., Lu, C. Y., Shea, C. M., Schmalzried, S. R. Macrophage functions are regulated by the substratum of murine decidual stromal cells Journal of Clinical Investigation 1990 85:1951-1958 DOI:10.1172/jci114658 PMID:2347918
- Lu, C. Y., Redline, R. W., Shea, C. M., Dustin, L. B., McKay, D. B. Pregnancy as a natural model of allograft tolerance - interactions between adherent macrophages and trophoblast populations Transplantation 1989 48:848-855 DOI:10.1097/00007890-198911000-00025 PMID:2573182
- Ertel, A. N., Millender, L. H., Nalebuff, E., McKay, D., Leslie, B. Flexor tendon ruptures in patients with rheumatoid-arthritis Journal of Hand Surgery-American Volume 1988 13A:860-866 DOI:10.1016/0363-5023(88)90260-2
- Allured, V. S., Collier, R. J., Carroll, S. F., McKay, D. B. Structure of exotoxin a of pseudomonas aeruginosa at 3.0 Å resolution Proceedings of the National Academy of Sciences of the United States of America 1986 83:1320-1324 DOI:10.1073/pnas.83.5.1320 PMID:3006045 PMCID:PMC323067