academic article

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• Gopalakrishna, K. N., Doddapuneni, K., Boyd, K. K., Masuho, I., Martemyanov, K. A., Artemyev, N. O. Interaction of transducin with uncoordinated 119 protein (UNC119) implications for the model of transducin trafficking in rod photoreceptors Journal of Biological Chemistry  2011 286:28954-28962  DOI:10.1074/jbc.M111.268821  PMID:21712387  PMCID:PMC3190703
• Cao, Y., Posokhova, E., Martemyanov, K. A. TRPM1 forms complexes with nyctalopin in vivo and accumulates in postsynaptic compartment of ON-bipolar neurons in mGluR6-dependent manner Journal of Neuroscience  2011 31:11521-11526  DOI:10.1523/jneurosci.1682-11.2011  PMID:21832182  PMCID:PMC3164511
• Masuho, I., Wakasugi-Masuho, H., Posokhova, E. N., Patton, J. R., Martemyanov, K. A. Type 5 G protein beta subunit (G beta 5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchors Journal of Biological Chemistry  2011 286:21806-21813  DOI:10.1074/jbc.M111.241513  PMID:21511947  PMCID:PMC3122235
• Porter, M. Y., Xie, K. Q., Pozharski, E., Koelle, M. R., Martemyanov, K. A. A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins Journal of Biological Chemistry  2010 285:41100-41112  DOI:10.1074/jbc.M110.163600  PMID:20959458  PMCID:PMC3003408
• Xie, K. Q., Allen, K. L., Kourrich, S., Colon-Saez, J., Thomas, M. J., Wickman, K., Martemyanov, K. A. G beta 5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling Nature Neuroscience  2010 13:661-663  DOI:10.1038/nn.2549  PMID:20453851  PMCID:PMC2876203
• Roloff, A. M., Anderson, G. R., Martemyanov, K. A., Thayer, S. A. Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic plasticity Journal of Neuroscience  2010 30:3072-3081  DOI:10.1523/jneurosci.4603-09.2010  PMID:20181604  PMCID:PMC2843151
• Masuho, I., Celver, J., Kovoor, A., Martemyanov, K. A. Membrane anchor GTPase-accelerating protein activity of RGS11.G beta(5) complex and accelerates inactivation of the mGluR6-G(o) signaling Journal of Biological Chemistry  2010 285:4781-4787  DOI:10.1074/jbc.M109.058511  PMID:20007977  PMCID:PMC2836083
• Cao, Y., Kolesnikov, A. V., Masuho, I., Kefalov, V. J., Martemyanov, K. A. Membrane anchoring subunits specify selective regulation of RGS9/Gbeta5 GAP complex in photoreceptor neurons Journal of Neuroscience  2010 30:13784-13793  DOI:10.1523/jneurosci.1191-10.2010  PMID:20943919  PMCID:PMC2975674
• Panicker, L. M., Zhang, J. H., Posokhova, E., Gastinger, M. J., Martemyanov, K. A., Simonds, W. F. Nuclear localization of the G protein beta 5/R7-regulator of G protein signaling protein complex is dependent on R7 binding protein Journal of Neurochemistry  2010 113:1101-1112  DOI:10.1111/j.1471-4159.2010.06616.x  PMID:20100282  PMCID:PMC2890294
• Posokhova, E., Uversky, V., Martemyanov, K. A. Proteomic identification of Hsc70 as a mediator of RGS9-2 degradation by in vivo interactome analysis Journal of Proteome Research  2010 9:1510-1521  DOI:10.1021/pr901022m  PMID:20095651  PMCID:PMC2890236
• Anderson, G. R., Cao, Y., Davidson, S., Truong, H. V., Pravetoni, M., Thomas, M. J., Wickman, K., Giesler, G. J., Martemyanov, K. A. R7BP complexes with RGS9-2 and RGS7 in the striatum differentially control motor learning and locomotor responses to cocaine Neuropsychopharmacology  2010 35:1040-1050  DOI:10.1038/npp.2009.212  PMID:20043004  PMCID:PMC2887292
• Posokhova, E., Wydeven, N., Allen, K. L., Wickman, K., Martemyanov, K. A. RGS6/G beta 5 complex accelerates IKaCh gating kinetics in atrial myocytes and modulates parasympathetic regulation of heart rate Circulation Research  2010 107:1350-1354  DOI:10.1161/circresaha.110.224212  PMID:20884879  PMCID:PMC3014848
• Anderson, G. R., Lujan, R., Martemyanov, K. A. Changes in striatal signaling induce remodeling of RGS complexes containing G beta 5 and R7BP subunits Molecular and Cellular Biology  2009 29:3033-3044  DOI:10.1128/mcb.01449-08  PMID:19332565  PMCID:PMC2682020
• Cao, Y., Masuho, I., Okawa, H., Xie, K. Q., Asami, J., Kammermeier, P. J., Maddox, D. M., Furukawa, T., Inoue, T., Sampath, A. P., Martemyanov, K. A. Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons Journal of Neuroscience  2009 29:9301-9313  DOI:10.1523/jneurosci.1367-09.2009  PMID:19625520  PMCID:PMC2731308
• Anderson, G. R., Posokhova, E., Martemyanov, K. A. The R7 RGS protein family: multi-subunit regulators of neuronal G protein signaling Cell Biochemistry and Biophysics  2009 54:33-46  DOI:10.1007/s12013-009-9052-9  PMID:19521673  PMCID:PMC2827338
• Martemyanov, K. A., Krispel, C. M., Lishko, P. V., Burns, M. E., Arshavsky, V. Y. Functional comparison of RGS9 splice isoforms in a living cell Proceedings of the National Academy of Sciences of the United States of America  2008 105:20988-20993  DOI:10.1073/pnas.0808941106  PMID:19098104  PMCID:PMC2634932
• Kim, H. J., Martemyanov, K. A., Thayer, S. A. Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death Journal of Neuroscience  2008 28:12604-12613  DOI:10.1523/jneurosci.2958-08.2008  PMID:19036954  PMCID:PMC2678679
• Cao, Y., Song, H. M., Okawa, H., Sampath, A. P., Sokolov, M., Martemyanov, K. A. Targeting of RGS7/G beta 5 to the dendritic tips of ON-bipolar cells is independent of its association with membrane anchor R7BP Journal of Neuroscience  2008 28:10443-10449  DOI:10.1523/jneurosci.3282-08.2008  PMID:18842904  PMCID:PMC2587022
• Anderson, G. R., Lujan, R., Semenov, A., Pravetoni, M., Posokhova, E. N., Song, J. H., Uversky, V., Chen, C. K., Wickman, K., Martemyanov, K. A. Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases Journal of Neuroscience  2007 27:14117-14127  DOI:10.1523/jneurosci.3884-07.2007  PMID:18094251
• Song, J. H., Song, H., Wensel, T. G., Sokolov, M., Martemyanov, K. A. Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina Molecular and Cellular Neuroscience  2007 35:311-319  DOI:10.1016/j.mcn.2007.03.006  PMID:17442586
• Anderson, G. R., Semenov, A., Song, J. H., Martemyanov, K. A. The membrane anchor R7BP controls the proteolytic stability of the striatal specific RGS protein, RGS9-2 Journal of Biological Chemistry  2007 282:4772-4781  DOI:10.1074/jbc.M610518200  PMID:17158100
• Baker, S. A., Martemyanov, K. A., Shavkunov, A. S., Arshavsky, V. Y. Kinetic mechanism of RGS9-1 potentiation by R9AP Biochemistry  2006 45:10690-10697  DOI:10.1021/bi060376a  PMID:16939221
• Krispel, C. M., Chen, D., Melling, N., Chen, Y. J., Martemyanov, K. A., Quillinan, N., Arshavsky, V. Y., Wensel, T. G., Chen, C. K., Burns, M. E. RGS expression rate-limits recovery of rod photoresponses Neuron  2006 51:409-416  DOI:10.1016/j.neuron.2006.07.010  PMID:16908407
• Song, J. H., Waataja, J. J., Martemyanov, K. A. Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP Journal of Biological Chemistry  2006 281:15361-15369  DOI:10.1074/jbc.M600749200  PMID:16574655
• Grant, J. E., Guo, L. W., Vestling, M. M., Martemyanov, K. A., Arshavsky, V. Y., Ruoho, A. E. The N terminus of GTP gamma S-activated transducin alpha-subunit interacts with the C terminus of the cGMP phosphodiesterase gamma-subunit Journal of Biological Chemistry  2006 281:6194-6202  DOI:10.1074/jbc.M509511200  PMID:16407279
• Martemyanov, K. A., Yoo, P. J., Skiba, N. P., Arshavsky, V. Y. R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family Journal of Biological Chemistry  2005 280:5133-5136  DOI:10.1074/jbc.C400596200  PMID:15632198
• Guo, L. W., Hajipour, A. R., Gavala, M. L., Arbabian, M., Martemyanov, K. A., Arshavsky, V. Y., Ruoho, A. E. Sulfhydryl-reactive, cleavable, and radioiodinatable benzophenone photoprobes for study of protein-protein interaction Bioconjugate Chemistry  2005 16:685-693  DOI:10.1021/bc050016k  PMID:15898738
• Keresztes, G., Martemyanov, K. A., Krispel, C. M., Mutai, H., Yoo, P. J., Maison, S. F., Burns, M. E., Arshavsky, V. Y., Heller, S. Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse Journal of Biological Chemistry  2004 279:1581-1584  DOI:10.1074/jbc.C300456200  PMID:14625292
• Nishiguchi, K. M., Sandberg, M. A., Kooijman, A. C., Martemyanov, K. A., Pott, J. W. R., Hagstrom, S. A., Arshavsky, V. Y., Berson, E. L., Dryja, T. P. Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation Nature  2004 427:75-78  DOI:10.1038/nature02170  PMID:14702087
• Martemyanov, K. A., Arshavsky, V. Y. Kinetic approaches to study the function of RGS9 isoforms Methods in Enzymology  2004 390:196-209  PMID:15488179
• Martemyanov, K. A., Hopp, J. A., Arshavsky, V. Y. Specificity of G protein-RGS protein recognition is regulated by affinity adapters Neuron  2003 38:857-862  DOI:10.1016/s0896-6273(03)00320-9  PMID:12818172
• Martemyanov, K. A., Lishko, P. V., Calero, N., Keresztes, G., Sokolov, M., Strissel, K. J., Leskov, I. B., Hopp, J. A., Kolesnikov, A. V., Chen, C. K., Lem, J., Heller, S., et al. The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo Journal of Neuroscience  2003 23:10175-10181  PMID:14614075
• Martemyanov, K. A., Arshavsky, V. Y. Noncatalytic domains of RGS9-1.Gbeta 5L play a decisive role in establishing its substrate specificity Journal of Biological Chemistry  2002 277:32843-32848  DOI:10.1074/jbc.M205170200  PMID:12093815
• Lishko, P. V., Martemyanov, K. A., Hopp, J. A., Arshavsky, V. Y. Specific binding of RGS9-G beta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activity Journal of Biological Chemistry  2002 277:24376-24381  DOI:10.1074/jbc.M203237200  PMID:12006596
• Martemyanov, K. A., Shirokov, V. A., Kurnasov, O. V., Gudkov, A. T., Spirin, A. S. Cell-free production of biologically active polypeptides: application to the synthesis of antibacterial peptide cecropin Protein Expression and Purification  2001 21:456-461  DOI:10.1006/prep.2001.1400  PMID:11281721
• Martemyanov, K. A., Liljas, A., Yarunin, A. S., Gudkov, A. T. Mutations in the G-domain of elongation factor G from thermus thermophilus affect both its interaction with GTP and fusidic acid Journal of Biological Chemistry  2001 276:28774-28778  DOI:10.1074/jbc.M102023200  PMID:11371559
• Skiba, N. P., Martemyanov, K. A., Elfenbein, A., Hopp, J. A., Bohm, A., Simonds, W. F., Arshavsky, V. Y. Rgs9-g beta 5 substrate selectivity in photoreceptors - opposing effects of constituent domains yield high affinity of rgs interaction with the g protein-effector complex Journal of Biological Chemistry  2001 276:37365-37372  DOI:10.1074/jbc.M106431200  PMID:11495924
• Martemyanov, K. A., Gudkov, A. T. Domain III of elongation factor G from thermus thermophilus is essential for induction of GTP hydrolysis on the ribosome Journal of Biological Chemistry  2000 275:35820-35824  DOI:10.1074/jbc.M002656200  PMID:10940297
• Martemyanov, K. A., Liljas, A., Gudkov, A. T. Extremely thermostable elongation factor G from Aquifex aeolicus: Cloning, expression, purification, and characterization in a heterologous translation system Protein Expression and Purification  2000 18:257-261  DOI:10.1006/prep.1999.1178  PMID:10733877
• Laurberg, M., Kristensen, O., Martemyanov, K., Gudkov, A. T., Nagaev, I., Hughes, D., Liljas, A. Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site Journal of Molecular Biology  2000 303:593-603  DOI:10.1006/jmbi.2000.4168  PMID:11054294
• Martemyanov, K. A., Gudkov, A. T. Domain IV of elongation factor G from thermus thermophilus is strictly required for translocation FEBS Letters  1999 452:155-159  DOI:10.1016/s0014-5793(99)00635-3  PMID:10386581
• Martemyanov, K. A., Yarunin, A. S., Liljas, A., Gudkov, A. T. An intact conformation at the tip of elongation factor G domain IV is functionally important FEBS Letters  1998 434:205-208  DOI:10.1016/s0014-5793(98)00982-x  PMID:9738479
• Martemyanov, K. A., Liljas, A., Gudkov, A. T. Increased functional activity of elongation factor G with G16V mutation in the GTP-binding domain Biochemistry-Moscow  1998 63:1216-1219  PMID:9864458
• Martemyanov, K. A., Spirin, A. S., Gudkov, A. T. Direct expression of pcr products in a cell-free transcription/translation system: synthesis of antibacterial peptide cecropin FEBS Letters  1997 414:268-270  DOI:10.1016/s0014-5793(97)01011-9  PMID:9315699
• Martemyanov, K. A., Spirin, A. S., Gudkov, A. T. Synthesis, cloning and expression of genes for antibacterial peptides: Cecropin, magainin and bombinin Biotechnology Letters  1996 18:1357-1362  DOI:10.1007/bf00129335