Loring, Jeanne

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- Kim, J. H., Alderton, A., Crook, J. M., Benvenisty, N., Brandsten, C., Firpo, M., Harrison, P. W., Kawamata, S., Kawase, E., Kurtz, A., Loring, J. F., Ludwig, T., et al. A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017 Stem Cells 2019 1130-1135 DOI:10.1002/stem.3003 PMID:31021472
- Colunga, T., Hayworth, M., Kress, S., Reynolds, D. M., Chen, L., Nazor, K. L., Baur, J., Singh, A. M., Loring, J. F., Metzger, M., Dalton, S. Human pluripotent stem cell-derived multipotent vascular progenitors of the mesothelium lineage have utility in tissue engineering and repair Cell Reports 2019 26:2566-2579 DOI:10.1016/j.celrep.2019.02.016 PMID:30840882
- Mangale, V., McIntyre, L. L., Walsh, C. M., Loring, J. F., Lane, T. E. Promoting remyelination through cell transplantation therapies in a model of viral-induced neurodegenerative disease Developmental Dynamics 2019 248:43-52 DOI:10.1002/dvdy.24658 PMID:30067309
- Loring, J. F. Wind-down of stem-cell institute leaves a void Nature 2019 572:155-155 DOI:10.1038/d41586-019-02346-5 PMID:31391566
- Kurtz, A., Seltmann, S., Bairoch, A., Bittner, M. S., Bruce, K., Capes-Davis, A., Clarke, L., Crook, J. M., Daheron, L., Dewender, J., Faulconbridge, A., Fujibuchi, W., et al. A standard nomenclature for referencing and authentication of pluripotent stem cells Stem Cell Reports 2018 10:1-6 DOI:10.1016/j.stemcr.2017.12.002 PMID:29320760 PMCID:PMC5768986
- Allison, T. F., Andrews, P. W., Avior, Y., Barbaric, I., Benvenisty, N., Bock, C., Brehm, J., Brustle, O., Damjanov, I., Elefanty, A., Felkner, D., Gokhale, P. J., et al. Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells Nature Communications 2018 9 DOI:10.1038/s41467-018-04011-3 PMID:29765017 PMCID:PMC5954055
- Loring, J. F. Autologous induced pluripotent stem cell-derived neurons to treat Parkinson's disease Stem Cells and Development 2018 DOI:10.1089/scd.2018.0107 PMID:29790422
- Sugarman, J., Shivakumar, S., Rook, M., Loring, J. F., Rehmann-Sutter, C., Taupitz, J., Reinhard-Rupp, J., Hildemann, S. Ethical considerations in the manufacture, male, and distribution of genome editing technologies American Journal of Bioethics 2018 18:3-6 DOI:10.1080/15265161.2018.1489653 PMID:30133390
- Boland, M. J., Nazor, K. L., Tran, H. T., Szucs, A., Lynch, C. L., Paredes, R., Tassone, F., Sanna, P. P., Hagerman, R. J., Loring, J. F. Molecular analyses of neurogenic defects in a human pluripotent stem cell model of fragile X syndrome Brain 2017 140:582-598 DOI:10.1093/brain/aww357 PMID:28137726
- O'Brien, C. M., Chy, H. S., Zhou, Q., Blumenfeld, S., Lambshead, J. W., Liu, X., Kie, J., Capaldo, B. D., Chung, T. L., Adams, T. E., Phan, T., Bentley, J. D., et al. New monoclonal antibodies to defined cell surface proteins on human pluripotent stem cells Stem Cells 2017 35:626-640 DOI:10.1002/stem.2558 PMID:28009074
- Amir, H., Touboul, T., Sabatini, K., Chhabra, D., Garitaonandia, I., Loring, J. F., Morey, R., Laurent, L. C. Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival Stem Cells 2017 35:872-885 DOI:10.1002/stem.2550 PMID:27888558
- Panopoulos, A. D., D'Antonio, M., Benaglio, P., Williams, R., Hashem, S. I., Schuldt, B. M., DeBoever, C., Arias, A. D., Garcia, M., Nelson, B. C., Harismendy, O., Jakubosky, D. A., et al. iPSCORE: A resource of 222 iPSC lines enabling functional characterization of genetic variation across a variety of cell types Stem Cell Reports 2017 8:1086-1100 DOI:10.1016/j.stemcr.2017.03.012 PMID:28410642 PMCID:PMC5390244
- Plaisted, W. C., Zavala, A., Hingco, E., Tran, H., Coleman, R., Lane, T. E., Loring, J. F., Walsh, C. M. Remyelination is correlated with regulatory T Cell induction following human embryoid body-derived neural precursor cell transplantation in a viral model of multiple sclerosis PLoS One 2016 11 DOI:10.1371/journal.pone.0157620 PMID:27310015 PMCID:PMC4911106
- Saragusty, J., Diecke, S., Drukker, M., Durrant, B., Friedrich Ben-Nun, I., Galli, C., Goritz, F., Hayashi, K., Hermes, R., Holtze, S., Johnson, S., Lazzari, G., et al. Rewinding the process of mammalian extinction Zoo Biology 2016 34:280-292 DOI:10.1002/zoo.21284 PMID:27142508
- Peterson, S. E., Garitaonandia, I., Loring, J. F. The tumorigenic potential of pluripotent stem cells: What can we do to minimize it? Bioessays 2016 38:S86-S95 DOI:10.1002/bies.201670915 PMID:27417126
- Bhutani, K., Nazor, K. L., Williams, R., Tran, H., Dai, H., Dzakula, Z., Cho, E. H., Pang, A. W. C., Rao, M., Cao, H., Schork, N. J., Loring, J. F. Whole-genome mutational burden analysis of three pluripotency induction methods Nature Communications 2016 7 DOI:10.1038/ncomms10536 PMID:26892726 PMCID:PMC4762882
- Gallego Romero, I., Pavlovic, B. J., Hernando-Herraez, I., Zhou, X., Ward, M. C., Banovich, N. E., Kagan, C. L., Burnett, J. E., Huang, C. H., Mitrano, A., Chavarria, C. I., Friedrich Ben-Nun, I., et al. A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics Elife 2015 4 DOI:10.7554/eLife.07103 PMID:26102527 PMCID:PMC4502404
- Gomez, S., Castellano, G., Mayol, G., Sunol, M., Queiros, A., Bibikova, M., Nazor, K. L., Loring, J. F., Lemos, I., Rodriguez, E., De Torres, C., Mora, J., et al. DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights Epigenomics 2015 7:1137-1153 DOI:10.2217/epi.15.49 PMID:26067621
- Rivera-Mulia, J. C., Buckley, Q., Sasaki, T., Zimmerman, J., Didier, R. A., Nazor, K., Loring, J. F., Lian, Z., Weissman, S., Robins, A. J., Schulz, T. C., Menendez, L., et al. Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells Genome Research 2015 25:1091-1103 DOI:10.1101/gr.187989.114 PMID:26055160 PMCID:PMC4509994
- French, A., Bravery, C., Smith, J., Chandra, A., Archibald, P., Gold, J. D., Artzi, N., Kim, H. W., Barker, R. W., Meissner, A., Wu, J. C., Knowles, J. C., et al. Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards Stem Cells Translational Medicine 2015 4:217-223 DOI:10.5966/sctm.2014-0233 PMID:25650438 PMCID:PMC4339854
- Wang, Y. C., Stein, J. W., Lynch, C. L., Tran, H. T., Lee, C. Y., Coleman, R., Hatch, A., Antontsev, V. G., Chy, H. S., O'Brien, C. M., Murthy, S. K., Laslett, A. L., et al. Glycosyltransferase ST6GAL1 contributes to the regulation of pluripotency in human pluripotent stem cells Scientific Reports 2015 5:13317 DOI:10.1038/srep13317 PMID:26304831 PMCID:PMC4548446
- Jia, H., Morris, C. D., Williams, R. M., Loring, J. F., Thomas, E. A. HDAC inhibition imparts beneficial transgenerational effects in Huntington's disease mice via altered DNA and histone methylation Proceedings of the National Academy of Sciences of the United States of America 2015 112:E56-E64 DOI:10.1073/pnas.1415195112 PMID:25535382 PMCID:PMC4291662
- Zdravkovic, T., Nazor, K. L., Larocque, N., Gormley, M., Donne, M., Hunkapillar, N., Giritharan, G., Bernstein, H. S., Wei, G., Hebrok, M., Zeng, X., Genbacev, O., et al. Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification Development 2015 142:4010-4025 DOI:10.1242/dev.122846 PMID:26483210 PMCID:PMC4712832
- Garitaonandia, I., Amir, H., Boscolo, F. S., Wambua, G. K., Schultheisz, H. L., Sabatini, K., Morey, R., Waltz, S., Wang, Y. C., Tran, H., Leonardo, T. R., Nazor, K., et al. Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions PLoS One 2015 10:e0118307 DOI:10.1371/journal.pone.0118307 PMID:25714340 PMCID:PMC4340884
- Andrews, P. W., Baker, D., Benvinisty, N., Miranda, B., Bruce, K., Brustle, O., Choi, M., Choi, Y. M., Crook, J. M., de Sousa, P. A., Dvorak, P., Freund, C., et al. Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI) Regenerative Medicine 2015 10:1-44 DOI:10.2217/rme.14.93 PMID:25675265
- Brandl, B., Schneider, S. A., Loring, J. F., Hardy, J., Gribbon, P., Muller, F. J. Stem cell reprogramming: basic implications and future perspective for movement disorders Movement Disorders 2015 30:301-312 DOI:10.1002/mds.26113 PMID:25546831
- Wang, Y. C., Lin, V., Loring, J. F., Peterson, S. E. The 'sweet' spot of cellular pluripotency: protein glycosylation in human pluripotent stem cells and its applications in regenerative medicine Expert Opinion on Biological Therapy 2015 15:679-687 DOI:10.1517/14712598.2015.1021329 PMID:25736263
- Boroda, A. V., Zacharenko, P. G., Maiorova, M. A., Peterson, S. E., Loring, J. F., Odintsova, N. A. The first steps towards generating induced pluripotent stem cells from cryopreserved skin biopsies of marine mammals Russian Journal of Marine Biology 2015 41:405-408 DOI:10.1134/s106307401505003x
- Muller, F. J., Loring, J. F. A compass for stem-cell differentiation Nature 2014 513:498-499 DOI:10.1038/nri3737 PMID:25234143 PMCID:PMC4191907
- Loring, J. F., McDevitt, T. C., Palecek, S. P., Schaffer, D. V., Zandstra, P. W., Nerem, R. M. A global assessment of stem cell engineering Tissue Engineering Part A 2014 20:2575-2589 DOI:10.1089/ten.tea.2013.0468 PMID:24428577 PMCID:PMC4195431
- Nazor, K. L., Boland, M. J., Bibikova, M., Klotzle, B., Yu, M., Glenn-Pratola, V. L., Schell, J. P., Coleman, R. L., Cabral-da-Silva, M. C., Schmidt, U., Peterson, S. E., He, C., et al. Application of a low cost array-based technique - TAB-Array - for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells Genomics 2014 104:358-367 DOI:10.1016/j.ygeno.2014.08.014 PMID:25179373 PMCID:PMC4342188
- Wolfe, L. M., Thiagarajan, R. D., Boscolo, F., Tache, V., Coleman, R. L., Kim, J., Kwan, W. K., Loring, J. F., Parast, M., Laurent, L. C. Banking placental tissue: an optimized collection procedure for genome-wide analysis of nucleic acids Placenta 2014 35:645-654 DOI:10.1016/j.placenta.2014.05.005 PMID:24951174 PMCID:PMC4847722
- Boland, M. J., Nazor, K. L., Loring, J. F. Epigenetic regulation of pluripotency and differentiation Circulation Research 2014 115:311-324 DOI:10.1161/circresaha.115.301517 PMID:24989490
- Soragni, E., Miao, W., Iudicello, M., Jacoby, D., De Mercanti, S., Clerico, M., Longo, F., Piga, A., Ku, S., Campau, E., Du, J., Penalver, P., et al. Epigenetic therapy for Friedreich ataxia Annals of Neurology 2014 76:489-508 DOI:10.1002/ana.24260 PMID:25159818 PMCID:PMC4361037
- Peterson, S. E., Loring, J. F. Genomic instability in pluripotent stem cells: implications for clinical applications Journal of Biological Chemistry 2014 289:4578-4584 DOI:10.1074/jbc.R113.516419 PMID:24362040 PMCID:PMC3931019
- Chen, L., Coleman, R., Leang, R., Tran, H., Kopf, A., Walsh, C. M., Sears-Kraxberger, I., Steward, O., Macklin, W. B., Loring, J. F., Lane, T. E. Human neural precursor cells promote neurologic recovery in a viral model of multiple sclerosis Stem Cell Reports 2014 2:825-837 DOI:10.1016/j.stemcr.2014.04.005 PMID:24936469 PMCID:PMC4050357
- Blurton-Jones, M., Spencer, B., Michael, S., Castello, N. A., Agazaryan, A. A., Davis, J. L., Muller, F. J., Loring, J. F., Masliah, E., LaFerla, F. M. Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models Stem Cell Research & Therapy 2014 5:46 DOI:10.1186/scrt440 PMID:25022790 PMCID:PMC4055090
- Marro, B. S., Blanc, C. A., Loring, J. F., Cahalan, M. D., Lane, T. E. Promoting remyelination: utilizing a viral model of demyelination to assess cell-based therapies Expert Review of Neurotherapeutics 2014 14:1169-1179 DOI:10.1586/14737175.2014.955854 PMID:25245576 PMCID:PMC4232205
- Wang, Y. C., Peterson, S. E., Loring, J. F. Protein post-translational modifications and regulation of pluripotency in human stem cells Cell Research 2014 24:143-160 DOI:10.1038/cr.2013.151 PMID:24217768 PMCID:PMC3915910
- Chen, C., Jiang, P., Xue, H., Peterson, S. E., Tran, H. T., McCann, A. E., Parast, M. M., Li, S., Pleasure, D. E., Laurent, L. C., Loring, J. F., Liu, Y., et al. Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells Nature Communications 2014 5:4430 DOI:10.1038/ncomms5430 PMID:25034944 PMCID:PMC4109022
- Li, Y., Moretto-Zita, M., Soncin, F., Wakeland, A., Wolfe, L., Leon-Garcia, S., Pandian, R., Pizzo, D., Cui, L., Nazor, K., Loring, J. F., Crum, C. P., et al. BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state Development 2013 140:3965-3976 DOI:10.1242/dev.092155 PMID:24004950 PMCID:PMC3775414
- Kurian, L., Sancho-Martinez, I., Nivet, E., Aguirre, A., Moon, K., Pendaries, C., Volle-Challier, C., Bono, F., Herbert, J. M., Pulecio, J., Xia, Y., Li, M., et al. Conversion of human fibroblasts to angioblast-like progenitor cells Nature Methods 2013 10:77-83 DOI:10.1038/nmeth.2255 PMID:23202434 PMCID:PMC3531579
- Liao, X., Xue, H., Wang, Y. C., Nazor, K. L., Guo, S., Trivedi, N., Peterson, S. E., Liu, Y., Loring, J. F., Laurent, L. C. Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions Journal of Cell Science 2013 126:3848-3861 DOI:10.1242/jcs.123570 PMID:23813959 PMCID:PMC3757328
- Jones, J. C., Sabatini, K., Liao, X., Tran, H. T., Lynch, C. L., Morey, R. E., Glenn-Pratola, V., Boscolo, F. S., Yang, Q., Parast, M. M., Liu, Y., Peterson, S. E., et al. Melanocytes derived from transgene-free human induced pluripotent stem cells Journal of Investigative Dermatology 2013 133:2104-2108 DOI:10.1038/jid.2013.139 PMID:23514962 PMCID:PMC3714355
- Nazor, K. L., Loring, J. F., Laurent, L. C. Equally potent? Does cellular reprogramming justify the abandonment of human embryonic stem cells? EMBO Reports 2012 13:890-894 DOI:10.1038/embor.2012.134 PMID:22986548 PMCID:PMC3463969
- MacArthur, C. C., Xue, H. P., Van Hoof, D., Lieu, P. T., Dudas, M., Fontes, A., Swistowski, A., Touboul, T., Seerke, R., Laurent, L. C., Loring, J. F., German, M. S., et al. Chromatin insulator elements block transgene silencing in engineered human embryonic stem cell lines at a defined chromosome 13 locus Stem Cells and Development 2012 21:191-205 DOI:10.1089/scd.2011.0163 PMID:21699412 PMCID:PMC3258440
- Fakunle, E. S., Loring, J. F. Ethnically diverse pluripotent stem cells for drug development Trends in Molecular Medicine 2012 18:709-716 DOI:10.1016/j.molmed.2012.10.007 PMID:23142148
- Ramskold, D., Luo, S. J., Wang, Y. C., Li, R., Deng, Q. L., Faridani, O. R., Daniels, G. A., Khrebtukova, I., Loring, J. F., Laurent, L. C., Schroth, G. P., Sandberg, R. Full-length mrna-seq from single-cell levels of rna and individual circulating tumor cells Nature Biotechnology 2012 30:777-782 DOI:10.1038/nbt.2282 PMID:22820318 PMCID:PMC3467340
- Nazor, K. L., Altun, G., Lynch, C., Tran, H., Harness, J. V., Slavin, I., Garitaonandia, I., Muller, F. J., Wang, Y. C., Boscolo, F. S., Fakunle, E., Dumevska, B., et al. Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives Cell Stem Cell 2012 10:620-634 DOI:10.1016/j.stem.2012.02.013 PMID:22560082 PMCID:PMC3348513
- Leonardo, T. R., Schultheisz, H. L., Loring, J. F., Laurent, L. C. The functions of micrornas in pluripotency and reprogramming Nature Cell Biology 2012 14:1114-1121 DOI:10.1038/ncb2613 PMID:23131918
- Muller, F. J., Schuldt, B. M., Williams, R., Mason, D., Altun, G., Papapetrou, E. P., Danner, S., Goldmann, J. E., Herbst, A., Schmidt, N. O., Aldenhoff, J. B., Laurent, L. C., et al. A bioinformatic assay for pluripotency in human cells Nature Methods 2011 8:315-317 DOI:10.1038/nmeth.1580 PMID:21378979 PMCID:PMC3265323
- Laurent, L. C., Ulitsky, I., Slavin, I., Tran, H., Schork, A., Morey, R., Lynch, C., Harness, J. V., Lee, S., Barrero, M. J., Ku, S., Martynova, M., et al. Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture Cell Stem Cell 2011 8:106-118 DOI:10.1016/j.stem.2010.12.003 PMID:21211785 PMCID:PMC3043464
- Sheridan, S. D., Theriault, K. M., Reis, S. A., Zhou, F., Madison, J. M., Daheron, L., Loring, J. F., Haggarty, S. J. Epigenetic characterization of the fmr1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile x syndrome PLoS One 2011 6:e26203 DOI:10.1371/journal.pone.0026203 PMID:22022567 PMCID:PMC3192166
- Harness, J. V., Turovets, N. A., Seiler, M. J., Nistor, G., Altun, G., Agapova, L. S., Ferguson, D., Laurent, L. C., Loring, J. F., Keirstead, H. S. Equivalence of conventionally-derived and parthenote-derived human embryonic stem cells PLoS One 2011 6:e14499 DOI:10.1371/journal.pone.0014499 PMID:21249129 PMCID:PMC3017547
- Golob, J. L., Kumar, R. M., Guenther, M. G., Pabon, L. M., Pratt, G. A., Loring, J. F., Laurent, L. C., Young, R. A., Murry, C. E. Evidence that gene activation and silencing during stem cell differentiation requires a transcriptionally paused intermediate state PLoS One 2011 6:e22416 DOI:10.1371/journal.pone.0022416 PMID:21886766 PMCID:PMC3158746
- Peterson, S. E., Chun, J., Loring, J. FISH analysis of human pluripotent stem cells Methods in Molecular Biology 2011 767:191-200 DOI:10.1007/978-1-61779-201-4_14 PMID:21822876
- Ben-Nun, I. F., Montague, S. C., Houck, M. L., Tran, H. T., Garitaonandia, I., Leonardo, T. R., Wang, Y. C., Charter, S. J., Laurent, L. C., Ryder, O. A., Loring, J. F. Induced pluripotent stem cells from highly endangered species Nature Methods 2011 8:829-831 DOI:10.1038/nmeth.1706 PMID:21892153
- Peterson, S. E., Westra, J. W., Rehen, S. K., Young, H., Bushman, D. M., Paczkowski, C. M., Yung, Y. C., Lynch, C. L., Tran, H. T., Nickey, K. S., Wang, Y. C., Laurent, L. C., et al. Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy PLoS One 2011 6:e23018 DOI:10.1371/journal.pone.0023018 PMID:21857983 PMCID:PMC3156708
- Wang, Y. C., Nakagawa, M., Garitaonandia, I., Slavin, I., Altun, G., Lacharite, R. M., Nazor, K. L., Tran, H. T., Lynch, C. L., Leonardo, T. R., Liu, Y., Peterson, S. E., et al. Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis Cell Research 2011 21:1551-1563 DOI:10.1038/cr.2011.148 PMID:21894191 PMCID:PMC3364725
- Liu, G. H., Suzuki, K., Qu, J., Sancho-Martinez, I., Yi, F., Li, M., Kumar, S., Nivet, E., Kim, J., Soligalla, R. D., Dubova, I., Goebl, A., et al. Targeted gene correction of laminopathy-associated lmna mutations in patient-specific ipscs Cell Stem Cell 2011 8:688-694 DOI:10.1016/j.stem.2011.04.019 PMID:21596650 PMCID:PMC3480729
- Peterson, S. E., Tran, H. T., Garitaonandia, I., Han, S., Nickey, K. S., Leonardo, T., Laurent, L. C., Loring, J. F. Teratoma generation in the testis capsule Journal of Visualized Experiments : JoVE 2011 e3177 DOI:10.3791/3177 PMID:22158256 PMCID:PMC3308584
- Hansen, K., Muller, F. J., Messing, M., Zeigler, F., Loring, J. F., Lamszus, K., Westphal, M., Schmidt, N. O. A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells Neuro-Oncology 2010 12:645-654 DOI:10.1093/neuonc/noq002 PMID:20156807 PMCID:PMC2940655
- Altun, G., Loring, J. F., Laurent, L. C. DNA methylation in embryonic stem cells Journal of Cellular Biochemistry 2010 109:1-6 DOI:10.1002/jcb.22374 PMID:19899110 PMCID:PMC3289679
- Laurent, L., Wong, E., Li, G., Huynh, T., Tsirigos, A., Ong, C. T., Low, H. M., Sung, K. W. K., Rigoutsos, I., Loring, J., Wei, C. L. Dynamic changes in the human methylome during differentiation Genome Research 2010 20:320-331 DOI:10.1101/gr.101907.109 PMID:20133333 PMCID:PMC2840979
- Ku, S., Soragni, E., Campau, E., Thomas, E. A., Altun, G., Laurent, L. C., Loring, J. F., Napierala, M., Gottesfeld, J. M. Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA.TTC triplet repeat instability Cell Stem Cell 2010 7:631-637 DOI:10.1016/j.stem.2010.09.014 PMID:21040903 PMCID:PMC2987635
- Abraham, S., Sheridan, S. D., Laurent, L. C., Albert, K., Stubban, C., Ulitsky, I., Miller, B., Loring, J. F., Rao, R. R. Propagation of human embryonic and induced pluripotent stem cells in an indirect co-culture system Biochemical and Biophysical Research Communications 2010 393:211-216 DOI:10.1016/j.bbrc.2010.01.101 PMID:20117095 PMCID:PMC2834855
- Laurent, L. C., Nievergelt, C. M., Lynch, C., Fakunle, E., Harness, J. V., Schmidt, U., Galat, V., Laslett, A. L., Otonkoski, T., Keirstead, H. S., Schork, A., Park, H. S., et al. Restricted ethnic diversity in human embryonic stem cell lines Nature Methods 2010 7:6-7 DOI:10.1038/nmeth0110-06 PMID:20038950
- Blurton-Jones, M., Kitazawa, M., Martinez-Coria, H., Castello, N. A., Muller, F. J., Loring, J. F., Yamasaki, T. R., Poon, W. W., Green, K. N., LaFerla, F. M. Neural stem cells improve cognition via bdnf in a transgenic model of alzheimer disease Proceedings of the National Academy of Sciences of the United States of America 2009 106:13594-13599 DOI:10.1073/pnas.0901402106 PMID:19633196 PMCID:PMC2715325
- Guibinga, G. H., Song, S. C., Loring, J., Friedmann, T. Characterization of the gene delivery properties of baculoviral-based virosomal vectors Journal of Virological Methods 2008 148:277-282 DOI:10.1016/j.jviromet.2007.11.007 PMID:18207578
- Laurent, L. C., Chen, J., Ulitsky, I., Mueller, F. J., Lu, C., Shamir, R., Fan, J. B., Loring, J. F. Comprehensive microrna profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence Stem Cells 2008 26:1506-1516 DOI:10.1634/stemcells.2007-1081 PMID:18403753
- Schwartz, P. H., Brick, D. J., Stover, A. E., Loring, J. F., Muller, F. J. Differentiation of neural lineage cells from human pluripotent stem cells Methods 2008 45:142-158 DOI:10.1016/j.ymeth.2008.03.007 PMID:18593611 PMCID:PMC2528840
- Orlovskaya, I., Schraufstatter, I., Loring, J., Khaldoyanidi, S. Hematopoietic differentiation of embryonic stem cells Methods 2008 45:159-167 DOI:10.1016/j.ymeth.2008.03.002 PMID:18593612
- Muller, F. J., Laurent, L. C., Kostka, D., Ulitsky, I., Williams, R., Lu, C., Park, I. H., Rao, M. S., Shamir, R., Schwartz, P. H., Schmidt, N. O., Loring, J. F. Regulatory networks define phenotypic classes of human stem cell lines Nature 2008 455:401-405 DOI:10.1038/nature07213 PMID:18724358 PMCID:PMC2637443
- West, M. D., Sargent, R. G., Long, J., Brown, C., Chu, J. S., Kessler, S., Derugin, N., Sampathkumar, J., Burrows, C., Vaziri, H., Williams, R., Chapman, K. B., et al. The actcellerate initiative: Large-scale combinatorial cloning of novel human embryonic stem cell derivatives Regenerative Medicine 2008 3:287-308 DOI:10.2217/17460751.3.3.287 PMID:18462054
- Bibikova, M., Laurent, L. C., Ren, B., Loring, J. F., Fan, J. B. Unraveling epigenetic regulation in embryonic stem cells Cell Stem Cell 2008 2:123-134 DOI:10.1016/j.stem.2008.01.005 PMID:18371433
- Serobyan, N., Jagannathan, S., Orlovskaya, I., Schraufstatter, I., Skok, M., Loring, J., Khaldoyanidi, S. The cholinergic system is involved in regulation of the development of the hematopoietic system Life Sciences 2007 80:2352-2360 DOI:10.1016/j.lfs.2007.04.017 PMID:17512954 PMCID:PMC2873871
- Josephson, R., Sykes, G., Liu, Y., Ording, C., Xu, W. N., Zeng, X. M., Shin, S., Loring, J., Maitra, A., Rao, M. S., Auerbach, J. M. A molecular scheme for improved characterization of human embryonic stem cell lines BMC Biology 2006 4:28 DOI:10.1186/1741-7007-4-28 PMID:16919167 PMCID:PMC1601965
- Mueller, F. J., Serobyan, N., Schraufstatter, I. U., DiScipio, R., Wakeman, D., Loring, J. F., Snyder, E. Y., Khaldoyanidi, S. K. Adhesive interactions between human neural stem cells and inflamed human vascular endothelium are mediated by integrins Stem Cells 2006 24:2367-2372 DOI:10.1634/stemcells.2005-0568 PMID:17071855 PMCID:PMC2885956
- Cai, J. L., Chen, J., Liu, Y., Miura, T., Luo, Y. Q., Loring, J. F., Freed, W. J., Rao, M. S., Zeng, X. M. Assessing self-renewal and differentiation in human embryonic stem cell lines Stem Cells 2006 24:516-530 DOI:10.1634/stemcells.2005-0143 PMID:16293578 PMCID:PMC1855239
- Katkov, II, Kim, M. S., Bajpai, R., Altman, Y. S., Mercola, M., Loring, J. F., Terskikh, A. V., Snyder, E. Y., Levine, F. Cryopreservation by slow cooling with dmso diminished production of oct-4 pluripotency marker in human embryonic stem cells Cryobiology 2006 53:194-205 DOI:10.1016/j.cryobiol.2006.05.005 PMID:16839540
- Muller, F. J., Snyder, E. Y., Loring, J. F. Gene therapy: Can neural stem cells deliver? Nature Reviews Neuroscience 2006 7:75-84 DOI:10.1038/nrn1829 PMID:16371952
- Liu, Y., Shin, S., Zeng, X., Zhan, M., Gonzalez, R., Mueller, F. J., Schwartz, C. M., Xue, H. P., Li, H., Baker, S. C., Chudin, E., Barker, D. L., et al. Genome wide profiling of human embryonic stem cells (hescs), their derivatives and embryonal carcinoma cells to develop base profiles of u.S. Federal government approved hesc lines BMC Developmental Biology 2006 6:20 DOI:10.1186/1471-213x/6/20 PMID:16672070
- Bibikova, M., Chudin, E., Wu, B., Zhou, L. X., Garcia, E. W., Liu, Y., Shin, S., Plaia, T. W., Auerbach, J. M., Arking, D. E., Gonzalez, R., Crook, J., et al. Human embryonic stem cells have a unique epigenetic signature Genome Research 2006 16:1075-1083 DOI:10.1101/gr.5319906 PMID:16899657 PMCID:PMC1557765
- Li, H., Liu, Y., Shin, S., Sun, Y., Loring, J. F., Mattson, M. P., Rao, M. S., Zhan, M. Transcriptome coexpression map of human embryonic stem cells BMC Genomics 2006 7:103 DOI:10.1186/1471-2164-7-103 PMID:16670017 PMCID:PMC1523211
- Snyder, E. Y., Loring, J. E. A role for stem cell biology in the physiological and pathological aspects of aging Journal of the American Geriatrics Society 2005 53:S287-S291 DOI:10.1111/j.1532-5415.2005.53491.x PMID:16131354
- Schwartz, C. M., Spivak, C. E., Baker, S. C., McDaniel, T. K., Loring, J. F., Nguyen, C., Chrest, F. J., Wersto, R., Arenas, E., Zeng, X. M., Freed, W. J., Rao, M. S. Ntera2: A model system to study dopaminergic differentiation of human embryonic stem cells Stem Cells and Development 2005 14:517-534 DOI:10.1089/scd.2005.14.517 PMID:16305337
- Dickey, C. A., Loring, J. F., Montgomery, J., Gordon, M. N., Eastman, P. S., Morgan, D. Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein plus presenilin-1 transgenic mice Journal of Neuroscience 2003 23:5219-5226 PMID:12832546
- Loring, J. F., Wen, X., Lee, J. M., Seilhamer, J., Somogyi, R. A gene expression profile of alzheimer's disease DNA and Cell Biology 2001 20:683-695 DOI:10.1089/10445490152717541 PMID:11788046
- Loring, J. F., Porter, J. G., Seilhamer, J., Kaser, M. R., Wesselschmidt, R. A gene expression profile of embryonic stem cells and embryonic stem cell-derived neurons Restorative Neurology and Neuroscience 2001 18:81-88 PMID:11847430
- Hanzel, D. K., Trojanowski, J. Q., Johnston, R. F., Loring, J. F. High-throughput quantitative histological analysis of alzheimer's disease pathology using a confocal digital microscanner Nature Biotechnology 1999 17:53-57 DOI:10.1038/5225 PMID:9920269
- Murai, H., Pierce, J. E. S., Raghupathi, R., Smith, D. H., Saatman, K. E., Trojanowski, J. Q., Lee, V. M. Y., Loring, J. F., Eckman, C., Younkin, S., McIntosh, T. K. Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury Journal of Comparative Neurology 1998 392:428-438 DOI:10.1002/(sici)1096-9861(19980323)392:4<428::aid-cne2>3.0.co;2-2 PMID:9514508
- Farese, R. V., Veniant, M. M., Cham, C. M., Flynn, L. M., Pierotti, V., Loring, J. F., Traber, M., Ruland, S., Stokowski, R. S., Huszar, D., Young, S. G. Phenotypic analysis of mice expressing exclusively apolipoprotein b48 or apolipoprotein b100 Proceedings of the National Academy of Sciences of the United States of America 1996 93:6393-6398 DOI:10.1073/pnas.93.13.6393 PMID:8692825
- Loring, J. F., Paszty, C., Rose, A., McIntosh, T. K., Mural, H., Pierce, J. E. S., Schramm, S. R., Wymore, K., Lee, V. M. Y., Trojanowski, J. Q., Peterson, K. R. Rational design of an animal model for alzheimer's disease: Introduction of multiple human genomic transgenes to reproduce ad pathology in a rodent Neurobiology of Aging 1996 17:173-182 DOI:10.1016/0197-4580(95)02076-4 PMID:8744398
- Paszty, C., Mohandas, N., Stevens, M. E., Loring, J. F., Liebhaber, S. A., Brion, C. M., Rubin, E. M. Lethal alpha-thalassemia created by gene targeting in mice and its genetic rescue Nature Genetics 1995 11:33-39 DOI:10.1038/ng0995-33 PMID:7550311
- Liu, C. P., Ueda, R., She, J. A., Sancho, J., Wang, B. P., Weddell, G., Loring, J., Kurahara, C., Dudley, E. C., Hayday, A., Terhorst, C., Huang, M. Abnormal T cell development in CD3-zeta-/- mutant mice and identification of a novel T cell population in the intestine EMBO Journal 1993 12:4863-4875 PMID:8223495 PMCID:PMC413941
- Chen, J. Z., Trounstine, M., Kurahara, C., Young, F., Kuo, C. C., Xu, Y., Loring, J. F., Alt, F. W., Huszar, D. B-cell development in mice that lack one or both immunoglobulin kappa-light chain genes EMBO Journal 1993 12:821-830 PMID:8458340 PMCID:PMC413279
- Buxbaum, J. D., Christensen, J. L., Ruefli, A. A., Greengard, P., Loring, J. F. Expression of APP in brains of transgenic mice containing the entire human APP gene Biochemical and Biophysical Research Communications 1993 197:639-645 DOI:10.1006/bbrc.1993.2527 PMID:8267600
- Chen, J. Z., Trounstine, M., Alt, F. W., Young, F., Kurahara, C., Loring, J. F., Huszar, D. Immunoglobulin gene rearrangement in b-cell deficient mice generated by targeted deletion of the j(h) locus International Immunology 1993 5:647-656 DOI:10.1093/intimm/5.6.647 PMID:8347558
- Choi, T. K., Hollenbach, P. W., Pearson, B. E., Ueda, R. M., Weddell, G. N., Kurahara, C. G., Woodhouse, C. S., Kay, R. M., Loring, J. F. Transgenic mice containing a human heavy-chain immunoglobulin gene fragment cloned in a yeast artificial chromosome Nature Genetics 1993 4:117-123 DOI:10.1038/ng0693-117 PMID:8348148
- Erickson, C. A., Loring, J. F., Lester, S. M. Migratory pathways of hnk-1-immunoreactive neural crest cells in the rat embryo Developmental Biology 1989 134:112-118 DOI:10.1016/0012-1606(89)90082-1 PMID:2659408
- Strecker, R. E., Miao, R., Loring, J. F. Survival and function of aggregate cultures of rat fetal dopamine neurons grafted in a rat model of parkinsons-disease Experimental Brain Research 1989 76:315-322 PMID:2569985
- Loring, J. F., Barker, D. L., Erickson, C. A. Migration and differentiation of neural crest and ventral neural tube cells in vitro: implications for in vitro and in vivo studies of the neural crest Journal of Neuroscience 1988 8:1001-1015 PMID:3346712
- Loring, J. F., Erickson, C. A. Neural crest cell migratory pathways in the trunk of the chick-embryo Developmental Biology 1987 121:220-236 DOI:10.1016/0012-1606(87)90154-0 PMID:3552788
- Cross, N. L., Loring, J. F., Harris, R. A novel form of sperm detachment from eggs of Urechis caupo Developmental Biology 1985 111:525-529 DOI:10.1016/0012-1606(85)90505-6
- Murphy, A. D., Barker, D. L., Loring, J. F., Kater, S. B. Sprouting and functional regeneration of an identified serotonergic neuron following axotomy Journal of Neurobiology 1985 16:137-151 DOI:10.1002/neu.480160206 PMID:2985748
book
- Nerem, R. M., Loring, J., McDevitt, T.C. and Palecek, S.P., Schaffer, D.V. and Zandstra, P.W. Stem cell engineering : a WTEC global assessment Science Policy Reports Springer 2014
- Peterson, S., Loring, J. F. Human stem cell manual : a laboratory guide Oxford: Academic. 2012
- Loring, J. F., Wesselschmidt, R. L., Schwartz, P. H. Human stem cell manual : a laboratory guide Amsterdam; Boston: Elsevier/Academic Press. 2007
patent
- Compositions and Methods for Defining Cells United States patent US Patent 8,442,772 (PluriTest) (2013).
- Alzheimer's Disease-associated Genes United States patent US Patent 6,682,888 (2004).
- Down Syndrome Critical Region 1-Like 1 Proteins United States patent US Patent 6,524,819 (2003).
- Transgenic Mouse Expressing Human Tau Gene United States patent US Patent 6,593,512 (2003).
- Methods For Producing Recombinant Mammalian Cells Harboring A Yeast Artificial Chromosome United States patent US Patent 5,981,175 (1999).
thesis
- Loring, J. F. Control of neural crest differentiation in vitro 1979

Scripps VIVO

Loring, Jeanne

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