recent publications
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academic article
- Harbut, M. B., Yang, B., Liu, R., Yano, T., Vilcheze, C., Cheng, B., Lockner, J. W., Guo, H., Yu, C., Franzblau, S. G., Petrassi, H. M., Jacobs, W. R., et al. Small molecules targeting mycobacterium tuberculosis type II NADH dehydrogenase exhibit antimycobacterial activity Angewandte Chemie-International Edition 2018 57:3478-3482 DOI:10.1002/anie.201800260 PMID:29388301
- Jacob, N. T., Anraku, K., Kimishima, A., Zhou, B., Collins, K. C., Lockner, J. W., Ellis, B. A., Janda, K. D. A bioconjugate leveraging xenoreactive antibodies to alleviate cocaine-induced behavior Chemical Communications 2017 53:8156-8159 DOI:10.1039/c7cc04055e PMID:28677711
- Galinato, M. H., Lockner, J. W., Fannon-Pavlich, M. J., Sobieraj, J. C., Staples, M. C., Somkuwar, S. S., Ghofranian, A., Chaing, S., Navarro, A. I., Joea, A., Luikart, B. W., Janda, K. D., et al. A synthetic small-molecule Isoxazole-9 protects against methamphetamine relapse Molecular Psychiatry 2017 23:629-638 DOI:10.1038/mp.2017.46 PMID:28348387 PMCID:PMC5617764
- Jacob, N. T., Lockner, J. W., Schlosburg, J. E., Ellis, B. A., Eubanks, L. M., Janda, K. D. Investigations of enantiopure nicotine haptens using an adjuvanting carrier in anti-nicotine vaccine development Journal of Medicinal Chemistry 2016 59:2523-2529 DOI:10.1021/acs.jmedchem.5b01676 PMID:26918428
- Lockner, J. W., Lively, J. M., Collins, K. C., Vendruscolo, J. C. M., Azar, M. R., Janda, K. D. A conjugate vaccine using enantiopure hapten imparts superior nicotine-binding capacity Journal of Medicinal Chemistry 2015 58:1005-1011 DOI:10.1021/jm501625j PMID:25493909
- Lockner, J. W., Eubanks, L. M., Choi, J. L., Lively, J. M., Schlosburg, J. E., Collins, K. C., Globisch, D., Rosenfeld-Gunn, R. J., Wilson, I. A., Janda, K. D. Flagellin as carrier and adjuvant in cocaine vaccine development Molecular Pharmaceutics 2015 12:653-662 DOI:10.1021/mp500520r PMID:25531528 PMCID:PMC4319694
- Collins, K. C., Schlosburg, J. E., Lockner, J. W., Bremer, P. T., Ellis, B. A., Janda, K. D. Lipid tucaresol as an adjuvant for methamphetamine vaccine development Chemical Communications 2014 50:4079-4081 DOI:10.1039/c4cc00682h PMID:24615284 PMCID:PMC4033696
- Jacob, N. T., Lockner, J. W., Kravchenko, V. V., Janda, K. D. Pharmacophore reassignment for induction of the immunosurveillance cytokine TRAIL Angewandte Chemie-International Edition 2014 53:6628-6631 DOI:10.1002/anie.201402133 PMID:24838721
- Schlosburg, J. E., Vendruscolo, L. F., Bremer, P. T., Lockner, J. W., Wade, C. L., Nunes, A. A., Stowe, G. N., Edwards, S., Janda, K. D., Koob, G. F. Dynamic vaccine blocks relapse to compulsive intake of heroin Proceedings of the National Academy of Sciences of the United States of America 2013 110:9036-9041 DOI:10.1073/pnas.1219159110 PMID:23650354 PMCID:PMC3670323
- Lockner, J. W., Ho, S. O., McCague, K. C., Chiang, S. M., Do, T. Q., Fujii, G., Janda, K. D. Enhancing nicotine vaccine immunogenicity with liposomes Bioorganic & Medicinal Chemistry Letters 2013 23:975-978 DOI:10.1016/j.bmcl.2012.12.048 PMID:23313243 PMCID:PMC3557556
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Dixon, D. D., Lockner, J. W., Zhou, Q. H., Baran, P. S.
Scalable, divergent synthesis of meroterpenoids via "borono-sclareolide"
Journal of the American Chemical Society
2012
134:8432-8435
DOI:10.1021/ja303937y
PMID:22583115
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Lockner, J. W., Dixon, D. D., Risgaard, R., Baran, P. S.
Practical radical cyclizations with arylboronic acids and trifluoroborates
Organic Letters
2011
13:5628-5631
DOI:10.1021/ol2023505
PMID:21923108
PMCID:PMC3193542
- Davis, C. E., Bailey, J. L., Lockner, J. W., Coates, R. M. Regio- and stereoselectivity of diethylaluminum azide opening of trisubstituted epoxides and conversion of the 3 degrees azidohydrin adducts to isoprenoid aziridines Journal of Organic Chemistry 2003 68:75-82 DOI:10.1021/jo026506c PMID:12515464