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Lockner, Jonathan
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Lockner, Jonathan

Graduate Student
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Positions

  • 2017 - Adjunct Faculty, San Diego Miramar College
  • 2017 - Adjunct Faculty, Point Loma Nazarene University
  • 2015 - 2016 Postdoctoral Fellow, California Institute for Biomedical Research (Calibr) , Scripps Research
  • 2011 - 2015 Research Associate, Scripps Research
  • 2003 - 2006 Senior Associate Scientist, Pfizer
  • 2001 - 2003 Associate Scientist, Pharmacia

Websites

  • Doctoral Dissertation
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Publications

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  • Publications without PubMed PMIDs

  • academic article

    • Harbut, M. B., Yang, B., Liu, R., Yano, T., Vilcheze, C., Cheng, B., Lockner, J. W., Guo, H., Yu, C., Franzblau, S. G., Petrassi, H. M., Jacobs, W. R., et al. Small molecules targeting mycobacterium tuberculosis type II NADH dehydrogenase exhibit antimycobacterial activity Angewandte Chemie-International Edition  2018 57:3478-3482  DOI:10.1002/anie.201800260  PMID:29388301
    • Jacob, N. T., Anraku, K., Kimishima, A., Zhou, B., Collins, K. C., Lockner, J. W., Ellis, B. A., Janda, K. D. A bioconjugate leveraging xenoreactive antibodies to alleviate cocaine-induced behavior Chemical Communications  2017 53:8156-8159  DOI:10.1039/c7cc04055e  PMID:28677711
    • Galinato, M. H., Lockner, J. W., Fannon-Pavlich, M. J., Sobieraj, J. C., Staples, M. C., Somkuwar, S. S., Ghofranian, A., Chaing, S., Navarro, A. I., Joea, A., Luikart, B. W., Janda, K. D., et al. A synthetic small-molecule Isoxazole-9 protects against methamphetamine relapse Molecular Psychiatry  2017 23:629-638  DOI:10.1038/mp.2017.46  PMID:28348387  PMCID:PMC5617764
    • Jacob, N. T., Lockner, J. W., Schlosburg, J. E., Ellis, B. A., Eubanks, L. M., Janda, K. D. Investigations of enantiopure nicotine haptens using an adjuvanting carrier in anti-nicotine vaccine development Journal of Medicinal Chemistry  2016 59:2523-2529  DOI:10.1021/acs.jmedchem.5b01676  PMID:26918428
    • Lockner, J. W., Eubanks, L. M., Choi, J. L., Lively, J. M., Schlosburg, J. E., Collins, K. C., Globisch, D., Rosenfeld-Gunn, R. J., Wilson, I. A., Janda, K. D. Flagellin as carrier and adjuvant in cocaine vaccine development Molecular Pharmaceutics  2015 12:653-662  DOI:10.1021/mp500520r  PMID:25531528  PMCID:PMC4319694
    • Lockner, J. W., Lively, J. M., Collins, K. C., Vendruscolo, J. C. M., Azar, M. R., Janda, K. D. A conjugate vaccine using enantiopure hapten imparts superior nicotine-binding capacity Journal of Medicinal Chemistry  2015 58:1005-1011  DOI:10.1021/jm501625j  PMID:25493909
    • Jacob, N. T., Lockner, J. W., Kravchenko, V. V., Janda, K. D. Pharmacophore reassignment for induction of the immunosurveillance cytokine TRAIL Angewandte Chemie-International Edition  2014 53:6628-6631  DOI:10.1002/anie.201402133  PMID:24838721
    • Collins, K. C., Schlosburg, J. E., Lockner, J. W., Bremer, P. T., Ellis, B. A., Janda, K. D. Lipid tucaresol as an adjuvant for methamphetamine vaccine development Chemical Communications  2014 50:4079-4081  DOI:10.1039/c4cc00682h  PMID:24615284  PMCID:PMC4033696
    • Schlosburg, J. E., Vendruscolo, L. F., Bremer, P. T., Lockner, J. W., Wade, C. L., Nunes, A. A., Stowe, G. N., Edwards, S., Janda, K. D., Koob, G. F. Dynamic vaccine blocks relapse to compulsive intake of heroin Proceedings of the National Academy of Sciences of the United States of America  2013 110:9036-9041  DOI:10.1073/pnas.1219159110  PMID:23650354  PMCID:PMC3670323
    • Lockner, J. W., Ho, S. O., McCague, K. C., Chiang, S. M., Do, T. Q., Fujii, G., Janda, K. D. Enhancing nicotine vaccine immunogenicity with liposomes Bioorganic & Medicinal Chemistry Letters  2013 23:975-978  DOI:10.1016/j.bmcl.2012.12.048  PMID:23313243  PMCID:PMC3557556
    • degree-related publication Dixon, D. D., Lockner, J. W., Zhou, Q. H., Baran, P. S. Scalable, divergent synthesis of meroterpenoids via "borono-sclareolide" Journal of the American Chemical Society  2012 134:8432-8435  DOI:10.1021/ja303937y  PMID:22583115
    • degree-related publication Lockner, J. W., Dixon, D. D., Risgaard, R., Baran, P. S. Practical radical cyclizations with arylboronic acids and trifluoroborates Organic Letters  2011 13:5628-5631  DOI:10.1021/ol2023505  PMID:21923108  PMCID:PMC3193542
    • Davis, C. E., Bailey, J. L., Lockner, J. W., Coates, R. M. Regio- and stereoselectivity of diethylaluminum azide opening of trisubstituted epoxides and conversion of the 3 degrees azidohydrin adducts to isoprenoid aziridines Journal of Organic Chemistry  2003 68:75-82  DOI:10.1021/jo026506c  PMID:12515464
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Background

education and training

  • Ph.D. in Chemistry, Scripps Research 2006 - 2011
  • B.S. in Chemistry, University of Illinois at Urbana-Champaign 1997 - 2001

advisee of

  • graduate advising relationship

    • Baran, Phil, Ph.D.  candidacy, 2007 - 2011
  • postdoc or fellow advising relationship

    • Janda, Kim, Ph.D.  candidacy, 2011 - 2015
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Contact

full name

  • Jonathan Wayne Lockner

geographic location

  • Scripps California 

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