recent publications
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academic article
- Meylan, F., Song, Y. J., Fuss, I., Villarreal, S., Kahle, E., Malm, I. J., Acharya, K., Ramos, H. L., Lo, L., Mentink-Kane, M. M., Wynn, T. A., Migone, T. S., et al. The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation Mucosal Immunology 2011 4:172-185 DOI:10.1038/mi.2010.67 PMID:20980995 PMCID:PMC3437258
- Migone, T. S., Subramanian, G. M., Zhong, J., Healey, L. M., Corey, A., Devalaraja, M., Lo, L., Ullrich, S., Zimmerman, J., Chen, A., Lewis, M., Meister, G., et al. Raxibacumab for the treatment of inhalational anthrax New England Journal of Medicine 2009 361:135-144 DOI:10.1056/NEJMoa0810603 PMID:19587338
- Hotte, S. J., Hirte, H. W., Chen, E. X., Siu, L. L., Le, L. H., Corey, A., Iacobucci, A., MacLean, M., Lo, L., Fox, N. L., Oza, A. M. A phase 1 study of mapatumumab (fully human monoclonal antibody to TRAIL-R1) in patients with advanced solid malignancies Clinical Cancer Research 2008 14:3450-3455 DOI:10.1158/1078-0432.ccr-07-1416 PMID:18519776
- Greco, F. A., Bonomi, P., Crawford, J., Kelly, K., Oh, Y., Halpern, W., Lo, L., Gallant, G., Klein, J. Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer Lung Cancer 2008 61:82-90 DOI:10.1016/j.lungcan.2007.12.011 PMID:18255187
- Gao, C., Mao, S. L., Lo, C. H. L., Wirsching, P., Lerner, R. A., Janda, K. D. Making artificial antibodies: A format for phage display of combinatorial heterodimeric arrays Proceedings of the National Academy of Sciences of the United States of America 1999 96:6025-6030 DOI:10.1073/pnas.96.11.6025 PMID:10339535
- Mao, S. L., Gao, C., Lo, C. H. L., Wirsching, P., Wong, C. H., Janda, K. D. Phage-display library selection of high-affinity human single-chain antibodies to tumor-associated carbohydrate antigens sialyl Lewis(x) and Lewis(x) Proceedings of the National Academy of Sciences of the United States of America 1999 96:6953-6958 DOI:10.1073/pnas.96.12.6953 PMID:10359820
- Gao, C., Lavey, B. J., Lo, C. H. L., Datta, A., Wentworth, P., Janda, K. D. Direct selection for catalysis from combinatorial antibody libraries using a boronic acid probe: Primary amide bond hydrolysis Journal of the American Chemical Society 1998 120:2211-2217 DOI:10.1021/ja9720220
- Janda, K. D., Lo, L. C., Lo, C. H. L., Sim, M. M., Wang, R., Wong, C. H., Lerner, R. A. Chemical selection for catalysis in combinatorial antibody libraries Science 1997 275:945-948 DOI:10.1126/science.275.5302.945 PMID:9020070
- Gao, C., Lo, C. H. L., Mao, S., Wirsching, P., Lerner, R. A., Janda, K. D., Lin, C. H. Making chemistry selectable by linking it to infectivity Proceedings of the National Academy of Sciences of the United States of America 1997 94:11777-11782 DOI:10.1073/pnas.94.22.11777 PMID:9342313
- Lo, C. H. L., Wentworth, P., Jung, K. W., Yoon, J., Ashley, J. A., Janda, K. D. Reactive immunization strategy generates antibodies with high catalytic proficiencies Journal of the American Chemical Society 1997 119:10251-10252 DOI:10.1021/ja971442m
- Lo, L. C., Lo, C. H. L., Janda, K. D., Kassel, D. B., Raushel, F. M. A versatile mechanism based reaction probe for the direct selection of biocatalysts Bioorganic & Medicinal Chemistry Letters 1996 6:2117-2120 DOI:10.1016/0960-894x(96)00379-4
- Yli-Kauhaluoma, J. T., Ashley, J. A., Lo, C. H. L., Coakley, J., Wirsching, P., Janda, K. D. Catalytic antibodies with peptidyl-prolyl cis-trans isomerase activity Journal of the American Chemical Society 1996 118:5496-5497 DOI:10.1021/ja954206p
- Lo, C. H. L., Gao, C., Mao, S. L., Matsui, K., Lerner, R. A., Janda, K. D. Chain shuffling: Investigations into the specificity and selectivity of antibody catalysis Israel Journal of Chemistry 1996 36:195-198
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Yli-Kauhaluoma, J. T., Ashley, J. A., Lo, C. H., Tucker, L., Wolfe, M. M., Janda, K. D.
Anti-metallocene antibodies: A new approach to enantioselective catalysis of the Diels-Alder reaction
Journal of the American Chemical Society
1995
117:7041-7047
DOI:10.1021/ja00132a001
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Wirsching, P., Ashley, J. A., Lo, C. H. L., Janda, K. D., Lerner, R. A.
Reactive immunization
Science
1995
270:1775-1782
DOI:10.1126/science.270.5243.1775
PMID:8525366
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Janda, K. D.*, Lo, C. H. L.*, Li, T. Y., Barbas, C. F., Wirsching, P., Lerner, R. A.
Direct selection for a catalytic mechanism from combinatorial antibody libraries
Proceedings of the National Academy of Sciences of the United States of America
1994
91:2532-2536
DOI:10.1073/pnas.91.7.2532
PMID:8146149
(* = equal contribution)
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Ashley, J. A., Lo, C. H. L., McElhaney, G. P., Wirsching, P., Janda, K. D.
A catalytic antibody model for plp-dependent decarboxylases
Journal of the American Chemical Society
1993
115:2515-2516
DOI:10.1021/ja00059a061
- Chiou, S. H.*, Lo, C. H.*, Chang, C. Y., Itoh, T., Kaji, H., Samejima, T. Ostrich crystallins. Structural characterization of delta-crystallin with enzymic activity Biochemical Journal 1991 273:295-300 PMID:1991029 PMCID:PMC1149845 (* = equal contribution)
- Lo, C. H., Chiou, S. H. Simple fractionation of phospholipase A2 analogues from snake venom by high-performance liquid chromatography Journal of Chromatography-Biomedical Applications 1990 530:129-136 DOI:10.1016/s0378-4347(00)82311-7 PMID:2277102
- Chiou, S. H., Chang, W. P., Lo, C. H. Biochemical comparison of lens crystallins from three reptilian species Biochimica et Biophysica Acta 1988 955:1-9 DOI:10.1016/0167-4838(88)90173-2 PMID:3382668
- Chiou, S. H., Chang, W. P., Chen, S. W., Lo, C. H. N-terminal sequences of gamma-crystallins from the amphibian lens and their homology with gamma-crystallins of other major classes of vertebrates International Journal of Peptide and Protein Research 1988 31:335-338 PMID:3259558
- Chiou, S. H., Chang, W. P., Lo, C. H., Chen, S. W. Sequence comparison of gamma-crystallins from the reptilian and other vertebrate species FEBS Letters 1987 221:134-138 DOI:10.1016/0014-5793(87)80367-8 PMID:3622758