recent publications
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academic article
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Naydenov, A. V., Horne, E. A., Cheah, C. S., Swinney, K., Hsu, K. L., Cao, J. K., Marrs, W. R., Blankman, J. L., Tu, S., Cherry, A. E., Fung, S., Wen, A., et al.
ABHD6 blockade exerts antiepileptic activity in PTZ-induced seizures and in spontaneous seizures in R6/2 mice
Neuron
2014
83:361-371
DOI:10.1016/j.neuron.2014.06.030
PMID:25033180
PMCID:PMC4136499
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Dominguez, E., Galmozzi, A., Chang, J. W., Hsu, K. L., Pawlak, J., Li, W., Godio, C., Thomas, J., Partida, D., Niessen, S., O'Brien, P. E., Russell, A. P., et al.
Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes
Nature Chemical Biology
2014
10:113-121
DOI:10.1038/nchembio.1429
PMID:24362705
PMCID:PMC3953460
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Holly, S. P., Chang, J. W., Li, W. W., Niessen, S., Phillips, R. M., Piatt, R., Black, J. L., Smith, M. C., Boulaftali, Y., Weyrich, A. S., Bergmeier, W., Cravatt, B. F., et al.
Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation
Chemistry & Biology
2013
20:1125-1134
DOI:10.1016/j.chembiol.2013.07.011
PMID:23993462
PMCID:PMC3948353
- Xu, H., Feely, S. L., Wang, X., Liu, D. X., Borda, J. T., Dufour, J., Li, W., Aye, P. P., Doxiadis, G. G., Khosla, C., Veazey, R. S., Sestak, K. Gluten-sensitive enteropathy coincides with decreased capability of intestinal T cells to secrete IL-17 and IL-22 in a macaque model for celiac disease Clinical Immunology 2013 147:40-49 DOI:10.1016/j.clim.2013.02.012 PMID:23518597 PMCID:PMC3732447
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Bachovchin, D. A., Ji, T. Y., Li, W. W., Simon, G. M., Blankman, J. L., Adibekian, A., Hoover, H., Niessen, S., Cravatt, B. F.
Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening
Proceedings of the National Academy of Sciences of the United States of America
2010
107:20941-20946
DOI:10.1073/pnas.1011663107
PMID:21084632
PMCID:PMC3000285
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Marrs, W. R., Blankman, J. L., Horne, E. A., Thomazeau, A., Lin, Y. H., Coy, J., Bodor, A. L., Muccioli, G. G., Hu, S. S. J., Woodruff, G., Fung, S., Lafourcade, M., et al.
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
Nature Neuroscience
2010
13:951-957
DOI:10.1038/nn.2601
PMID:20657592
PMCID:PMC2970523
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Long, J. Z., Jin, X., Adibekian, A., Li, W. W., Cravatt, B. F.
Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases
Journal of Medicinal Chemistry
2010
53:1830-1842
DOI:10.1021/jm9016976
PMID:20099888
PMCID:PMC2828288
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Long, J. Z., Li, W. W., Booker, L., Burston, J. J., Kinsey, S. G., Schlosburg, J. E., Pavon, F. J., Serrano, A. M., Selley, D. E., Parsons, L. H., Lichtman, A. H., Cravatt, B. F.
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
Nature Chemical Biology
2009
5:37-44
DOI:10.1038/nchembio.129
PMID:19029917
PMCID:PMC2605181
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Li, W. W., Blankman, J. L., Cravatt, B. F.
A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases
Journal of the American Chemical Society
2007
129:9594-9595
DOI:10.1021/ja073650c
PMID:17629278
- Li, W., Lam, Y. A facile solid-phase synthesis of 1,2,4,5-tetrasubstituted imidazoles using sodium benzenesulfinate as a traceless linker Journal of Combinatorial Chemistry 2005 7:644-647 DOI:10.1021/cc049818x PMID:16153057
- Li, W., Lam, Y. Solid-phase synthesis of 3,4-dihydro-1H-pyrimidine-2-ones using sodium benzenesulfinate as a traceless linker Journal of Combinatorial Chemistry 2005 7:721-725 DOI:10.1021/cc0500295 PMID:16153067
- Li, W., Chen, Y., Lam, Y. Solid-phase synthesis of 3,4-dihydro-1H-pyrimidine-2-ones using sodium benzenesulfinate as a traceless linker Tetrahedron Letters 2004 45:6545-6547 DOI:10.1016/j.tetlet.2004.07.051
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