recent publications
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academic article
- Fischer, E. C., Hashimoto, K., Zhang, Y., Feldman, A. W., Dien, V. T., Karadeema, R. J., Adhikary, R., Ledbetter, M. P., Krishnamurthy, R., Romesberg, F. E. New codons for efficient production of unnatural proteins in a semisynthetic organism Nature Chemical Biology 2020 16:570-576 DOI:10.1038/s41589-020-0507-z PMID:32251411
- Ledbetter, M. P., Craig, J. M., Karadeema, R. J., Noakes, M. T., Kim, H. C., Abell, S. J., Huang, J. R., Anderson, B. A., Krishnamurthy, R., Gundlach, J. H., Romesberg, F. E. Nanopore sequencing of an expanded genetic alphabet reveals high-fidelity replication of a predominantly hydrophobic unnatural base pair Journal of the American Chemical Society 2020 142:2110-2114 DOI:10.1021/jacs.9b09808 PMID:31985216
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Ledbetter, M. P., Malyshev, D. A., Romesberg, F. E.
Site-specific labeling of DNA via PCR with an expanded genetic alphabet
Methods in Molecular Biology
2019
1973:193-212
DOI:10.1007/978-1-4939-9216-4_13
PMID:31016704
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Ledbetter, M. P., Romesberg, F. E.
Editorial overview: Expanding the genetic alphabet and code
Current Opinion in Chemical Biology
2018
46:A1-A2
DOI:10.1016/j.cbpa.2018.09.007
PMID:30270151
- Ellefson, J. W., Ledbetter, M. P., Ellington, A. D. Directed evolution of a synthetic phylogeny of programmable Trp repressors Nature Chemical Biology 2018 14:361-367 DOI:10.1038/s41589-018-0006-7 PMID:29483643
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Feldman, A. W., Fischer, E. C., Ledbetter, M. P., Liao, J. Y., Chaput, J. C., Romesberg, F. E.
A tool for the import of natural and unnatural nucleoside triphosphates into bacteria
Journal of the American Chemical Society
2018
140:1447-1454
DOI:10.1021/jacs.7b11404
PMID:29338214
PMCID:PMC5809120
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Ledbetter, M. P., Karadeema, R. J., Romesberg, F. E.
Reprograming the replisome of a semisynthetic organism for the expansion of the genetic alphabet
Journal of the American Chemical Society
2018
140:758-765
DOI:10.1021/jacs.7b11488
PMID:29309130
PMCID:PMC5793209
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Feldman, A. W., Ledbetter, M. P., Zhang, Y., Romesberg, F. E.
Reply to Hettinger: Hydrophobic unnatural base pairs and the expansion of the genetic alphabet
Proceedings of the National Academy of Sciences of the United States of America
2017
114:E6478-E6479
DOI:10.1073/pnas.1708259114
PMID:28768812
PMCID:PMC5559050
- Ledbetter, M. P., Hwang, T. W., Stovall, G. M., Ellington, A. D. Continuous in vitro evolution of a ribozyme ligase: a model experiment for the evolution of a biomolecule Biochemistry and Molecular Biology Education 2013 41:433-442 DOI:10.1002/bmb.20742 PMID:24214216