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Lazear, Michael
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Lazear, Michael

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Publications

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  • academic article

    • degree-related publication Abbasov, M. E., Kavanagh, M. E., Ichu, T. A., Lazear, M. R., Tao, Y. F., Crowley, V. M., Ende, C. W. A., Hacker, S. M., Ho, J., Dix, M. M., Suciu, R., Hayward, M. M., et al. A proteome-wide atlas of lysine-reactive chemistry Nature Chemistry  2021  DOI:10.1038/s41557-021-00765-4  PMID:34504315
    • degree-related publication Vinogradova, E. V., Zhang, X. Y., Remillard, D., Lazar, D. C., Suciu, R. M., Wang, Y. J., Bianco, G., Yamashita, Y., Crowley, V. M., Schafroth, M. A., Yokoyama, M., Konrad, D. B., et al. An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells Cell  2020 182:1009-1026  DOI:10.1016/j.cell.2020.07.001  PMID:32730809
    • degree-related publication Hacker, S. M., Backus, K. M., Lazear, M. R., Forli, S., Correia, B. E., Cravatt, B. F. Global profiling of lysine reactivity and ligandability in the human proteome Nature Chemistry  2017 9:1181-1190  DOI:10.1038/nchem.2826  PMID:29168484
    • degree-related publication Niessen, S., Dix, M. M., Barbas, S., Potter, Z. E., Lu, S., Brodsky, O., Planken, S., Behenna, D., Almaden, C., Gajiwala, K. S., Ryan, K., Ferre, R., et al. Proteome-wide map of targets of T790M-EGFR-directed covalent inhibitors Cell Chemical Biology  2017 24:1388-1400  DOI:10.1016/j.chembiol.2017.08.017  PMID:28965727  PMCID:PMC5693604
    • Torrens-Spence, M. P., Lazear, M., von Guggenberg, R., Ding, H., Li, J. Investigation of a substrate-specifying residue within Papaver somniferum and Catharanthus roseus aromatic amino acid decarboxylases Phytochemistry  2014 106:37-43  DOI:10.1016/j.phytochem.2014.07.007  PMID:25107664
    • Torrens-Spence, M. P., von Guggenberg, R., Lazear, M., Ding, H., Li, J. Diverse functional evolution of serine decarboxylases: identification of two novel acetaldehyde synthases that uses hydrophobic amino acids as substrates BMC Plant Biology  2014 14  DOI:10.1186/s12870-014-0247-x  PMID:25230835  PMCID:PMC4177580
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Background

education and training

  • Ph.D. in Chemical Biology, Scripps Research 2015 -
  • B.S. in Biochemistry, Virginia Polytechnic Institute and State University 2011 - 2015

advisee of

  • graduate advising relationship

    • Cravatt, Benjamin, Ph.D.  candidacy, 2016 -
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Contact

full name

  • Michael Ryan Lazear

geographic location

  • Scripps California 

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