recent publications
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academic article
- Mayeux, J. M., Kono, D. H., Pollard, K. M. Development of experimental silicosis in inbred and outbred mice depends on instillation volume Scientific Reports 2019 9 DOI:10.1038/s41598-019-50725-9 PMID:31578388
- Pollard, K. M., Cauvi, D. M., Toomey, C. B., Hultman, P., Kono, D. H. Mercury-induced inflammation and autoimmunity Biochimica Et Biophysica Acta-General Subjects 2019 1863 DOI:10.1016/j.bbagen.2019.02.001 PMID:30742953 PMCID:PMC6689266
- Gonzalez-Quintial, R., Mayeux, J. M., Kono, D. H., Theofilopoulos, A. N., Pollard, K. M., Baccala, R. Silica exposure and chronic virus infection synergistically promote lupus-like systemic autoimmunity in mice with low genetic predisposition Clinical Immunology 2019 205:75-82 DOI:10.1016/j.clim.2019.06.003 PMID:31175964 PMCID:PMC6646094
- Gonzalez-Quintial, R., Nguyen, A., Kono, D. H., Oldstone, M. B. A., Theofilopoulos, A. N., Baccala, R. Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predisposition PLoS One 2018 13 DOI:10.1371/journal.pone.0203118 PMID:30199535 PMCID:PMC6130858
- Mayeux, J. M., Escalante, G. M., Christy, J. M., Pawar, R. D., Kono, D. H., Pollard, K. M. Silicosis and silica-induced autoimmunity in the diversity outbred mouse Frontiers in Immunology 2018 9 DOI:10.3389/fimmu.2018.00874 PMID:29755467 PMCID:PMC5932595
- Theofilopoulos, A. N., Kono, D. H., Baccala, R. The multiple pathways to autoimmunity Nature Immunology 2017 18:716-724 DOI:10.1038/ni.3731 PMID:28632714
- Lawson, B. R., Gonzalez-Quintial, R., Eleftheriadis, T., Farrar, M. A., Miller, S. D., Sauer, K., McGavern, D. B., Kono, D. H., Baccala, R., Theofilopoulos, A. N. Interleukin-7 is required for CD4(+) T cell activation and autoimmune neuroinflammation Clinical Immunology 2015 161:260-269 DOI:10.1016/j.clim.2015.08.007 PMID:26319414 PMCID:PMC4658267
- Maine, C. J., Marquardt, K., Scatizzi, J. C., Pollard, K. M., Kono, D. H., Sherman, L. A. The effect of the autoimmunity-associated gene, PTPN22, on a BXSB-derived model of lupus Clinical Immunology 2015 156:65-73 DOI:10.1016/j.clim.2014.11.003 PMID:25463433 PMCID:PMC4291082
- Cauvi, D. M., Gabriel, R., Kono, D. H., Hultman, P., Pollard, K. M. A tandem repeat in decay accelerating factor 1 is associated with severity of murine mercury-induced autoimmunity Autoimmune Diseases 2014 2014:260613 DOI:10.1155/2014/260613 PMID:24818014 PMCID:PMC4003777
- Pollard, K. M., Kono, D. H. Requirements for "Fire and ICE" differ between animal models of autoimmunity: comment on the article by Kahlenberg et al Arthritis & Rheumatology 2014 66:2310-2311 DOI:10.1002/art.38678 PMID:24757010
- Tardif, V., Manenkova, Y., Berger, M., Hoebe, K., Zuo, J. P., Yuan, C., Kono, D. H., Theofilopoulos, A. N., Lawson, B. R. Critical role of transmethylation in TLR signaling and systemic lupus erythematosus Clinical Immunology 2013 147:133-143 DOI:10.1016/j.clim.2013.02.018 PMID:23583916 PMCID:PMC3634912
- Baccala, R., Gonzalez-Quintial, R., Blasius, A. L., Rimann, I., Ozato, K., Kono, D. H., Beutler, B., Theofilopoulos, A. N. Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus Proceedings of the National Academy of Sciences of the United States of America 2013 110:2940-2945 DOI:10.1073/pnas.1222798110 PMID:23382217 PMCID:PMC3581947
- Pollard, K. M., Cauvi, D. M., Toomey, C. B., Morris, K. V., Kono, D. H. Interferon-gamma and systemic autoimmunity Discovery Medicine 2013 87:123-131 PMID:23998448 PMCID:PMC3934799
- Pollard, K. M., Kono, D. H. Requirements for innate immune pathways in environmentally induced autoimmunity BMC Medicine 2013 11:100 DOI:10.1186/1741-7015-11-100 PMID:23557436 PMCID:PMC3616845
- Pollard, K. M., Kono, D. H. Requirements for innate immune pathways in environmentally induced autoimmunity BMC Medicine 2013 11:100 DOI:10.1186/1741-7015-11-100 PMID:23557436 PMCID:PMC3616845
- Koh, Y. T., Scatizzi, J. C., Gahan, J. D., Lawson, B. R., Baccala, R., Pollard, K. M., Beutler, B. A., Theofilopoulos, A. N., Kono, D. H. Role of nucleic acid-sensing TLRs in diverse autoantibody specificities and anti-nuclear antibody-producing B cells Journal of Immunology 2013 190:4982-4990 DOI:10.4049/jimmunol.1202986 PMID:23589617 PMCID:PMC3729324
- Kono, D. H., Baccala, R., Theofilopoulos, A. N. TLRs and interferons: a central paradigm in autoimmunity Current Opinion in Immunology 2013 25:720-727 DOI:10.1016/j.coi.2013.10.006 PMID:24246388 PMCID:PMC4309276
- Germolec, D., Kono, D. H., Pfau, J. C., Pollard, K. M. Animal models used to examine the role of the environment in the development of autoimmune disease: Findings from an NIEHS Expert Panel Workshop Journal of Autoimmunity 2012 39:285-293 DOI:10.1016/j.jaut.2012.05.020 PMID:22748431 PMCID:PMC3465484
- Baccala, R., Gonzalez-Quintial, R., Schreiber, R. D., Lawson, B. R., Kono, D. H., Theofilopoulos, A. N. Anti-IFN-alpha/beta receptor antibody treatment ameliorates disease in lupus-predisposed mice Journal of Immunology 2012 189:5976-5984 DOI:10.4049/jimmunol.1201477 PMID:23175700 PMCID:PMC3530925
- Pollard, K. M., Hultman, P., Toomey, C. B., Cauvi, D. M., Hoffman, H. M., Hamel, J. C., Kono, D. H. Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity Journal of Autoimmunity 2012 39:323-331 DOI:10.1016/j.jaut.2012.04.003 PMID:22578563 PMCID:PMC3570757
- Gronwall, C., Chen, Y. F., Vas, J., Khanna, S., Thiel, S., Corr, M., Kono, D. H., Silverman, G. J. MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses Proceedings of the National Academy of Sciences of the United States of America 2012 109:19745-19750 DOI:10.1073/pnas.1211868109 PMID:23139409 PMCID:PMC3511709
- Scatizzi, J. C., Haraldsson, M. K., Pollard, K. M., Theofilopoulos, A. N., Kono, D. H. The lbw2 locus promotes autoimmune hemolytic anemia Journal of Immunology 2012 188:3307-3314 DOI:10.4049/jimmunol.1103561 PMID:22371393 PMCID:PMC3311724
- Lawson, B. R., Eleftheriadis, T., Tardif, V., Gonzalez-Quintial, R., Baccala, R., Kono, D. H., Theofilopoulos, A. N. Transmethylation in immunity and autoimmunity Clinical Immunology 2012 143:8-21 DOI:10.1016/j.clim.2011.10.007 PMID:22364920 PMCID:PMC3780779
- Theofilopoulos, A. N., Kono, D. H., Beutler, B., Baccala, R. Intracellular nucleic acid sensors and autoimmunity Journal of Interferon and Cytokine Research 2011 31:867-886 DOI:10.1089/jir.2011.0092 PMID:22029446 PMCID:PMC3234494
- Gonzalez-Quintial, R., Lawson, B. R., Scatizzi, J. C., Craft, J., Kono, D. H., Baccala, R., Theofilopoulos, A. N. Systemic autoimmunity and lymphoproliferation are associated with excess IL-7 and inhibited by IL-7R alpha blockade PLoS One 2011 6:e27528 DOI:10.1371/journal.pone.0027528 PMID:22102903 PMCID:PMC3213145
- Ait-Azzouzene, D., Kono, D. H., Gonzalez-Quintial, R., McHeyzer-Williams, L. J., Lim, M., Wickramarachchi, D., Gerdes, T., Gavin, A. L., Skog, P., McHeyzer-Williams, M. G., Nemazee, D., Theofilopoulos, A. N. Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice Journal of Immunology 2010 185:1015-1027 DOI:10.4049/jimmunol.1000698 PMID:20554953 PMCID:PMC3641794
- Wickramarachchi, D. C., Theofilopoulos, A. N., Kono, D. H. Immune pathology associated with altered actin cytoskeleton regulation Autoimmunity 2010 43:64-75 DOI:10.3109/08916930903374634 PMID:20001423 PMCID:PMC3660107
- Arandjelovic, S., Wickramarachchi, D., Hemmers, S., Leming, S. S., Kono, D. H., Mowen, K. A. Mast cell function is not altered by Coronin-1A deficiency Journal of Leukocyte Biology 2010 88:737-745 DOI:10.1189/jlb.0310131 PMID:20643816 PMCID:PMC2974433
- Theofilopoulos, A. N., Gonzalez-Quintial, R., Lawson, B. R., Koh, Y. T., Stern, M. E., Kono, D. H., Beutler, B., Baccala, R. Sensors of the innate immune system: Their link to rheumatic diseases Nature Reviews Rheumatology 2010 6:146-156 DOI:10.1038/nrrheum.2009.278 PMID:20142813 PMCID:PMC4437225
- Pollard, K. M., Hultman, P., Kono, D. H. Toxicology of autoimmune diseases Chemical Research in Toxicology 2010 23:455-466 DOI:10.1021/tx9003787 PMID:20078109 PMCID:PMC3076021
- Kono, D. H., Haraldsson, M. K., Lawson, B. R., Pollard, K. M., Koh, Y. T., Du, X., Arnold, C. N., Baccala, R., Silverman, G. J., Beutler, B. A., Theofilopoulos, A. N. Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus Proceedings of the National Academy of Sciences of the United States of America 2009 106:12061-12066 DOI:10.1073/pnas.0905441106 PMID:19574451 PMCID:PMC2715524
- Odegard, J. M., DiPlacido, L. D., Greenwald, L., Kashgarian, M., Kono, D. H., Dong, C., Flavell, R. A., Craft, J. ICOS controls effector function but not trafficking receptor expression of kidney-infiltrating effector T cells in murine lupus Journal of Immunology 2009 182:4076-4084 DOI:10.4049/jimmunol.0800758 PMID:19299705 PMCID:PMC2746004
- Chen, Y. F., Khanna, S., Goodyear, C. S., Park, Y. B., Raz, E., Thiel, S., Gronwall, C., Vas, J., Boyle, D. L., Corr, M., Kono, D. H., Silverman, G. J. Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis Journal of Immunology 2009 183:1346-1359 DOI:10.4049/jimmunol.0900948 PMID:19564341 PMCID:PMC2713016
- Baccala, R., Gonzalez-Quintial, R., Lawson, B. R., Stern, M. E., Kono, D. H., Beutler, B., Theofilopoulos, A. N. Sensors of the innate immune system: Their mode of action Nature Reviews Rheumatology 2009 5:448-456 DOI:10.1038/nrrheum.2009.136 PMID:19597511
- Odegard, J. M., Marks, B. R., DiPlacido, L. D., Poholek, A. C., Kono, D. H., Dong, C., Flavell, R. A., Craft, J. ICOS-dependent extrafollicular helper T cells elicit igg production via IL-21 in systemic autoimmunity Journal of Experimental Medicine 2008 205:2873-2886 DOI:10.1084/jem.20080840 PMID:18981236 PMCID:PMC2585848
- Haraldsson, M. K., Louis-Dit-Sully, C. A., Lawson, B. R., Sternik, G., Santiago-Raber, M. L., Gascoigne, N. R. J., Theofilopoulos, A. N., Kono, D. H. The lupus-related Lmb3 locus contains a disease-suppressing coronin-1A gene mutation Immunity 2008 28:40-51 DOI:10.1016/j.immuni.2007.11.023 PMID:18199416 PMCID:PMC2274909
- Santiago-Raber, M. L., Haraldsson, M. K., Theofilopoulos, A. N., Kono, D. H. Characterization of reciprocal MRL-Fas(lpr) and C57BL/6-Fas(lpr) congenic mice reveals significant effects from Lmb3 Journal of Immunology 2007 178:8195-8202 PMID:17548658
- Baccala, R., Hoebe, K., Kono, D. H., Beutler, B., Theofilopoulos, A. N. TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity Nature Medicine 2007 13:543-551 DOI:10.1038/nm1590 PMID:17479100
- Kono, D. H., Theofilopoulos, A. N. Genetics of SLE in mice Springer Seminars in Immunopathology 2006 28:83-96 DOI:10.1007/s00281-006-0030-7 PMID:16972052
- Watson, L. C., Moffatt-Blue, C. S., McDonald, R. Z., Kompfner, E., Ait-Azzouzene, D., Nemazee, D., Theofilopoulos, A. N., Kono, D. H., Feeney, A. J. Paucity of V-D-D-J rearrangements and V-H replacement events in lupus prone and nonautoimmune TdT(-/-) and TdT(+/+) mice Journal of Immunology 2006 177:1120-1128 PMID:16818769
- Haraldsson, M. K., dela Paz, N. G., Kuan, J. G., Gilkeson, G. S., Theofilopoulos, A. N., Kono, D. H. Autoimmune alterations induced by the New Zealand Black Lbw2 locus in BWF1 mice Journal of Immunology 2005 174:5065-5073 PMID:15814738
- Pollard, K. M., Hultman, P., Kono, D. H. Immunology and genetics of induced systemic autoimmunity Autoimmunity Reviews 2005 4:282-288 DOI:10.1016/j.autrev.2004.12.005 PMID:15990075
- Baccala, R., Kono, D. H., Theofilopoulos, A. N. Interferons as pathogenic effectors in autoimmunity Immunological Reviews 2005 204:9-26 DOI:10.1111/j.0105-2896.2005.00252.x PMID:15790347
- Theofilopoulos, A. N., Baccala, R., Beutler, B., Kono, D. H. Type I interferons (α/β) in immunity and autoimmunity Annual Review of Immunology 2005 23:307-336 DOI:10.1146/annurev.immunol.23.021704.115843 PMID:15771573
- Pollard, K. M., Arnush, M., Hultman, P., Kono, D. H. Costimulation requirements of induced murine systemic autoimmune disease Journal of Immunology 2004 173:5880-5887 PMID:15494542
- Lawson, B. R., Baccala, R., Song, J. X., Croft, M., Kono, D. H., Theofilopoulos, A. N. Deficiency of the cyclin kinase inhibitor P21(WAF-1/CIP-1) promotes apoptosis of activated/memory T cells and inhibits spontaneous systemic autoirnmunity Journal of Experimental Medicine 2004 199:547-557 DOI:10.1084/jem.20031685 PMID:14970181 PMCID:PMC2211831
- Robey, I. F., Peterson, M., Horwitz, M. S., Kono, D. H., Stratmann, T., Theofilopoulos, A. N., Sarvetnick, N., Teyton, L., Feeney, A. J. Terminal deoxynucleotidyltransferase deficiency decreases autoimmune disease in diabetes-prone nonobese diabetic mice and lupus-prone MRL-Fas(lpr) mice Journal of Immunology 2004 172:4624-4629 PMID:15034081
- Kono, D. H., Park, M. S., Theofilopoulos, A. N. Genetic complementation in female (BXSB x NZW)F-2 mice Journal of Immunology 2003 171:6442-6447 PMID:14662843
- Kono, D. H., Baccala, R., Theofilopoulos, A. N. Inhibition of lupus by genetic alteration of the interferon-alpha/beta receptor Autoimmunity 2003 36:503-510 DOI:10.1080/08916930310001624665 PMID:14984027
- Santiago-Raber, M. L., Baccala, R., Haraldsson, K. M., Choubey, D., Stewart, T. A., Kono, D. H., Theofilopoulos, A. N. Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice Journal of Experimental Medicine 2003 197:777-788 DOI:10.1084/jem.20021996 PMID:12642605 PMCID:PMC2193854
- Pollard, K. M., Hultman, P., Kono, D. H. Using single-gene deletions to identify checkpoints in the progression of systemic autoimmunity Annals of the New York Academy of Sciences 2003 987:236-239 PMID:12727644
- Theofilopoulos, A. N., Kono, D. H. A genetic analysis of lupus Allergy 2002 57:67-74 DOI:10.1034/j.1398-9995.57.s72.22.x PMID:12144559
- Lawson, B. R., Kono, D. H., Theofilopoulos, A. N. Deletion of p21 (WAF-1/Cip1) does not induce systemic autoimmunity in female BXSB mice Journal of Immunology 2002 168:5928-5932 PMID:12023399
- Gorgani, N. N., Smith, B. A., Kono, D. H., Theofilopoulos, A. N. Histidine-rich glycoprotein binds to DNA and Fc gamma RI and potentiates the ingestion of apoptotic cells by macrophages Journal of Immunology 2002 169:4745-4751 PMID:12391183
- Theofilopoulos, A. N., Kono, D. H. Genetics of systemic autoimmunity and glomerulonephritis in mouse models of lupus Nephrology Dialysis Transplantation 2001 16:65-67 PMID:11568247
- Kono, D. H., Park, M. S., Szydlik, A., Haraldsson, K. M., Kuan, J. D., Pearson, D. L., Hultman, P., Pollard, K. M. Resistance to xenobiotic-induced autoimmunity maps to chromosome 1 Journal of Immunology 2001 167:2396-2403 PMID:11490030
- Santiago-Raber, M. L., Lawson, B. R., Dummer, W., Barnhouse, M., Koundouris, S., Wilson, C. B., Kono, D. H., Theofilopoulos, A. N. Role of cyclin kinase inhibitor p21 in systemic autoimmunity Journal of Immunology 2001 167:4067-4074 PMID:11564828
- Merriman, T. R., Cordell, H. J., Eaves, I. A., Danoy, P. A., Coraddu, F., Barber, R., Cucca, F., Broadley, S., Sawcer, S., Comptson, A., Wordsworth, P., Shatford, J., et al. Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases Diabetes 2001 50:184-194 DOI:10.2337/diabetes.50.1.184 PMID:11147786
- Theofilopoulos, A. N., Dummer, W., Kono, D. H. T cell homeostasis and systemic autoimmunity Journal of Clinical Investigation 2001 108:335-340 DOI:10.1172/jci12173 PMID:11489923
- Feeney, A. J., Lawson, B. R., Kono, D. H., Theofilopoulos, A. N. Terminal deoxynucleotidyl transferase deficiency decreases autoimmune disease in MRL-Fas(lpr) mice Journal of Immunology 2001 167:3486-3493 PMID:11544342
- Lawson, B. R., Koundouris, S. I., Barnhouse, M., Dummer, W., Baccala, R., Kono, D. H., Theofilopoulos, A. N. The role of alpha beta(+) T cells and homeostatic T cell proliferation in Y-chromosome-associated murine lupus Journal of Immunology 2001 167:2354-2360 PMID:11490025
- Pollard, K. M., Pearson, D. L., Hultman, P., Deane, T. N., Lindh, U., Kono, D. H. Xenobiotic acceleration of idiopathic systemic autoimmunity in lupus-prone BXSB mice Environmental Health Perspectives 2001 109:27-33 DOI:10.2307/3434917 PMID:11171521 PMCID:PMC1242047
- Kono, D. H., Balomenos, D., Park, M. S., Theofilopoulos, A. N. Development of lupus in BXSB mice is independent of IL-4 Journal of Immunology 2000 164:38-42 PMID:10604990
- Kono, D. H., Theofilopoulos, A. N. Genetic studies in systemic autoimmunity and aging Immunologic Research 2000 21:111-122 DOI:10.1385/ir:21:2-3:111 PMID:10852108
- Lawson, B. R., Prud'homme, G. J., Chang, Y. G., Gardner, H. A., Kuan, J., Kono, D. H., Theofilopoulos, A. N. Treatment of murine lupus with cDNA encoding IFN-gamma R/Fc Journal of Clinical Investigation 2000 106:207-215 DOI:10.1172/jci10167 PMID:10903336
- Pollard, K. M., Pearson, D. L., Hultman, P., Hildebrandt, B., Kono, D. H. Lupus-prone mice as models to study xenobiotic-induced acceleration of systemic autoimmunity Environmental Health Perspectives 1999 107:729-735 DOI:10.2307/3434334 PMID:10502538
- Maloy, K. J., Burkhart, C., Freer, G., Rulicke, T., Pircher, H., Kono, D. H., Theofilopoulos, A. N., Ludewig, B., Hoffmann-Rohrer, U., Zinkernagel, R. M., Hengartner, H. Qualitative and quantitative requirements for CD4(+) T cell-mediated antiviral protection Journal of Immunology 1999 162:2867-2874 PMID:10072535
- Theofilopoulos, A. N., Kono, D. H. The genes of systemic autoimmunity Proceedings of the Association of American Physicians 1999 111:228-240 DOI:10.1046/j.1525-1381.1999.99244.x PMID:10354363
- Vidal, S., Kono, D. H., Theofilopoulos, A. N. Loci predisposing to autoimmunity in MRL-Fas(lpr) and C57BL/6-Fas(lpr) mice Journal of Clinical Investigation 1998 101:696-702 DOI:10.1172/jci1817 PMID:9449705
- Ishikawa, T., Kono, D., Chung, J., Fowler, P., Theofilopoulos, A., Kakumu, S., Chisari, F. V. Polyclonality and multispecificity of the CTL response to a single viral epitope Journal of Immunology 1998 161:5842-5850 PMID:9834062
- Kuan, J., Kono, D. H. TGFBR1 maps to chromosome 4 Mammalian Genome 1998 9:95-96 DOI:10.1007/s003359900695 PMID:9434964
- Kono, D. H., Balomenos, D., Pearson, D. L., Park, M. S., Hildebrandt, B., Hultman, P., Pollard, K. M. The prototypic Th2 autoimmunity induced by mercury is dependent on IFN-gamma and not Th1/Th2 imbalance Journal of Immunology 1998 161:234-240 PMID:9647229
- Norris, K., Norris, F., Kono, D. H., Vestergaard, H., Pedersen, O., Theofilopoulos, A. N., Moller, N. P. H. Expression of protein-tyrosine phosphatases in the major insulin target tissues FEBS Letters 1997 415:243-248 DOI:10.1016/s0014-5793(97)01133-2 PMID:9357975
- Sabzevari, H., Propp, S., Kono, D. H., Theofilopoulos, A. N. G1 arrest and high expression of cyclin kinase and apoptosis inhibitors in accumulated activated memory phenotype CD4(+) cells of older lupus mice European Journal of Immunology 1997 27:1901-1910 DOI:10.1002/eji.1830270813 PMID:9295025
- Shao, H., Kono, D. H., Chen, L. Y., Rubin, E. M., Kaye, J. Induction of the early growth response (Egr) family of transcription factors during thymic selection Journal of Experimental Medicine 1997 185:731-744 DOI:10.1084/jem.185.4.731 PMID:9034151
- Kono, D. H., Theofilopoulos, A. N. Genetic contributions to SLE Journal of Autoimmunity 1996 9:437-452 DOI:10.1006/jaut.1996.0061 PMID:8864819
- Kono, D. H., Owens, D. G., Wechsler, A. R. Jak3 maps to chromosome 8 Mammalian Genome 1996 7:476-477 DOI:10.1007/s003359900145 PMID:8662243
- Duncan, S. R., Valentine, V., Roglic, M., Elias, D. J., Pekny, K. W., Theodore, J., Kono, D. H., Theofilopoulos, A. N. T cell receptor biases and clonal proliferations among lung transplant recipients with obliterative bronchiolitis Journal of Clinical Investigation 1996 97:2642-2650 DOI:10.1172/jci118714 PMID:8647959
- Manca, F., Fenoglio, D., Valle, M. T., Lipira, G., Kunkl, A., Balderas, R. S., Baccala, R. G., Kono, D. H., Ferraris, A., Saverino, D., Lancia, F., Lozzi, L., et al. Human T-helper cells specific for HIV reverse-transcriptase - possible role in intrastructural help for HIV envelope-specific antibodies European Journal of Immunology 1995 25:1217-1223 DOI:10.1002/eji.1830250513 PMID:7539750
- Balomenos, D., Balderas, R. S., Mulvany, K. P., Kaye, J., Kono, D. H., Theofilopoulos, A. N. Incomplete T-cell receptor V-beta allelic exclusion and dual V-beta-expressing cells Journal of Immunology 1995 155:3308-3312 PMID:7561023
- Prudhomme, G. J., Kono, D. H., Theofilopoulos, A. N. Quantitative polymerase chain-reaction analysis reveals marked overexpression of interleukin-1-beta, interleukin-10 and interferon-gamma messenger-RNA in the lymph-nodes of lupus-prone mice Molecular Immunology 1995 32:495-503 DOI:10.1016/0161-5890(95)00024-9 PMID:7783752
- Theofilopoulos, A. N., Baccala, R., Gonzalez-Quintial, R., Kono, D. H., Balderas, R. S., Macphee, R., Duncan, S. R., Roglic, M. T-cell repertoires in health and disease Annals of the New York Academy of Sciences 1995 756:53-65 DOI:10.1111/j.1749-6632.1995.tb44481.x PMID:7645874
- Churchill, M. E. A., Stura, E. A., Pinilla, C., Appel, J. R., Houghten, R. A., Kono, D. H., Balderas, R. S., Fieser, G. G., Schulzegahmen, U., Wilson, I. A. Crystal-structure of a peptide complex of antiinfluenza peptide antibody-Fab-26/9 - comparison of 2 different antibodies bound to the same peptide antigen Journal of Molecular Biology 1994 241:534-556 DOI:10.1006/jmbi.1994.1530 PMID:7520084
- Kono, D. H., Burlingame, R. W., Owens, D. G., Kuramochi, A., Balderas, R. S., Balomenos, D., Theofilopoulos, A. N. Lupus susceptibility loci in New-Zealand mice Proceedings of the National Academy of Sciences of the United States of America 1994 91:10168-10172 DOI:10.1073/pnas.91.21.10168 PMID:7937857
- Smith, L. R., Kono, D. H., Asthana, D., Balderas, R. S., Lindstrom, J., Theofilopoulos, A. N., Fujii, Y. T-cell receptor V-beta-15 dominates the antiacetylcholine receptor response in Lewis rat T-cell lines Journal of Immunology 1994 152:2596-2600 PMID:8133067
- Seki, S., Kono, D. H., Balderas, R. S., Theofilopoulos, A. N. V-beta repertoire of murine hepatic T-cells - implication for selection of double-negative alpha-beta(+) T-cells Journal of Immunology 1994 153:637-646 PMID:8021501
- Baccala, R., Vandekerckhove, B. A. E., Jones, D., Kono, D. H., Roncarolo, M. G., Theofilopoulos, A. N. Bacterial superantigens mediate T-cell deletions in the mouse severe combined immunodeficiency human liver thymus model Journal of Experimental Medicine 1993 177:1481-1485 DOI:10.1084/jem.177.5.1481 PMID:8478618
- Cole, B. C., Balderas, R. A., Ahmed, E. A., Kono, D., Theofilopoulos, A. N. Genomic composition and allelic polymorphisms influence-V-beta usage by the mycoplasma-arthritidis superantigen Journal of Immunology 1993 150:3291-3299 PMID:8468471
- Theofilopoulos, A. N., Balderas, R. S., Baccala, R., Kono, D. H. T-cell receptor genes in autoimmunity Annals of the New York Academy of Sciences 1993 681:33-46 DOI:10.1111/j.1749-6632.1993.tb22867.x PMID:8357184
- Kono, D. H., Baccala, R., Balderas, R. S., Kovac, S. J., Heald, P. W., Edelson, R. L., Theofilopoulos, A. N. Application of a multiprobe RNase protection assay and junctional sequences to define V beta gene diversity in Sezary-syndrome American Journal of Pathology 1992 140:823-830 PMID:1562047 PMCID:PMC1886373
- Merrill, J. E., Kono, D. H., Clayton, J., Ando, D. G., Hinton, D. R., Hofman, F. M. Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice Proceedings of the National Academy of Sciences of the United States of America 1992 89:574-578 DOI:10.1073/pnas.89.2.574 PMID:1370583
- Vandekerckhove, B. A. E., Baccala, R., Jones, D., Kono, D. H., Theofilopoulos, A. N., Roncarolo, M. G. Thymic selection of the human T-cell receptor V-beta repertoire in SCID-HU mice Journal of Experimental Medicine 1992 176:1619-1624 DOI:10.1084/jem.176.6.1619 PMID:1460421
- Smith, L. R., Kono, D. H., Kammuller, M. E., Balderas, R. S., Theofilopoulos, A. N. V-beta repertoire in rats and implications for endogenous superantigens European Journal of Immunology 1992 22:641-645 DOI:10.1002/eji.1830220305 PMID:1312471
- Smith, L. R., Kono, D. H., Theofilopoulos, A. N. Complexity and sequence identification of 24 rat V-beta genes Journal of Immunology 1991 147:375-379 PMID:1828824
- Baccala, R., Kono, D. H., Walker, S., Balderas, R. S., Theofilopoulos, A. N. Genomically imposed and somatically modified human thymocyte V-beta gene repertoires Proceedings of the National Academy of Sciences of the United States of America 1991 88:2908-2912 DOI:10.1073/pnas.88.7.2908 PMID:2011599
- Padula, S. J., Lingenheld, E. G., Stabach, P. R., Chou, C. H. J., Kono, D. H., Clark, R. B. Identification of encephalitogenic V-beta-4-bearing T-cells in SJL mice. Further evidence for the V-region disease hypothesis Journal of Immunology 1991 146:879-883 PMID:1703184
- Plaza, A., Kono, D. H., Theofilopoulos, A. N. New human V-beta genes and polymorphic variants Journal of Immunology 1991 147:4360-4365 PMID:1684376
- Hood, L., Kumar, V., Osman, G., Beall, S. S., Gomez, C., Funkhouser, W., Kono, D. H., Nickerson, D., Zaller, D. M., Urban, J. L. Autoimmune-disease and T-cell immunological recognition Cold Spring Harbor Symposia on Quantitative Biology 1989 54:859-874 PMID:2484250
- Theofilopoulos, A. N., Singer, P. A., Kofler, R., Kono, D. H., Duchosal, M. A., Balderas, R. S. B-cell and T-cell antigen receptor repertoires in lupus arthritis murine models Springer Seminars in Immunopathology 1989 11:335-368 PMID:2694405
- Ando, D. G., Clayton, J., Kono, D., Urban, J. L., Sercarz, E. E. Encephalitogenic T-cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype Cellular Immunology 1989 124:132-143 DOI:10.1016/0008-8749(89)90117-2 PMID:2478300
- Gross, U., Chen, J. H., Kono, D. H., Lobo, J. G., Yu, D. T. Y. High degree of conservation between ribosomal-proteins of Yersinia-pseudotuberculosis and Escherichia-coli Nucleic Acids Research 1989 17:3601-3602 DOI:10.1093/nar/17.9.3601 PMID:2657663
- Clayton, J. P., Gammon, G. M., Ando, D. G., Kono, D. H., Hood, L., Sercarz, E. E. Peptide-specific prevention of experimental allergic encephalomyelitis - neonatal tolerance induced to the dominant T-cell determinant of myelin basic-protein Journal of Experimental Medicine 1989 169:1681-1691 DOI:10.1084/jem.169.5.1681 PMID:2469764
- Urban, J. L., Kumar, V., Kono, D. H., Gomez, C., Horvath, S. J., Clayton, J., Ando, D. G., Sercarz, E. E., Hood, L. Restricted use of T-cell receptor V-genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy Cell 1988 54:577-592 DOI:10.1016/0092-8674(88)90079-7 PMID:2456857
- Kono, D. H., Urban, J. L., Horvath, S. J., Ando, D. G., Saavedra, R. A., Hood, L. Two minor determinants of myelin basic protein induce experimental allergic encephalomyelitis in SJL/J mice Journal of Experimental Medicine 1988 168:213-227 DOI:10.1084/jem.168.1.213 PMID:2456367 PMCID:PMC2188984
- Chen, J. H., Kono, D. H., Yong, Z., Park, M. S., Oldstone, Mmba, Yu, D. T. Y. A Yersinia-pseudotuberculosis protein which cross-reacts with HLA-B27 Journal of Immunology 1987 139:3003-3011 PMID:2444647
- Ogasawara, M., Kono, D. H., Yu, D. T. Y. Mimicry of human histocompatibility HLA-B27 antigens by Klebsiella-pneumoniae Infection and Immunity 1986 51:901-908 PMID:3512439 PMCID:PMC260984
- Ogasawara, M., Granfors, K., Kono, D. H., Hill, J. L., Yu, D. T. Y. A Yersinia-enterocolitica serotype 0-3 lipopolysaccharide-specific monoclonal-antibody reacts more strongly with bacteria cultured at room-temperature than those cultured at 37-degrees-C Journal of Immunology 1985 135:553-559 PMID:2582049
- Ogasawara, M., Kobayashi, S., Arai, S., Laheji, K., Hill, J. L., Kono, D. H., Yu, D. T. Y. A heat-modifiable outer-membrane protein carries an antigen specific for the species Yersinia-enterocolitica and Yersinia-pseudotuberculosis Journal of Immunology 1985 135:1430-1436 PMID:2409152
- Kono, D. H., Ogasawara, M., Yu, D. T. Y. An animal-model to study serum immunoglobulin response to infection by Yersinia-entercocolitica Clinical and Experimental Rheumatology 1985 3:117-121 PMID:4017307
- Ogasawara, M., Kobayashi, S., Hill, J. L., Kono, D. H., Yu, D. T. Y. Rabbit antisera against 3 different bacteria which can induce reactive arthritis - analysis by ELISA, immunoprecipitation and western Blot Immunology 1985 54:665-676 PMID:3884493 PMCID:PMC1453566
- Yu, D. T. Y., Ogasawara, M., Hill, J. L., Kono, D. H. Study of Reiters-syndrome, with special emphasis on Yersinia-enterocolitica Immunological Reviews 1985 86:27-45 DOI:10.1111/j.1600-065X.1985.tb01136.x PMID:3876266
- Kono, D. H., Ogasawara, M., Effros, R. B., Park, M. S., Waldord, R. L., Yu, D. T. Y. Ye-1, a monoclonal-antibody that cross-reacts with HLA-B27 lymphoblastoid cell-lines and an arthritis causing bacteria Clinical and Experimental Immunology 1985 61:503-508 PMID:3878239 PMCID:PMC1577260
- Maeda, K., Kono, D., Kobayashi, S., Brenner, M. B., Yu, D. T. Y. A study of the specificity of the direct binding between bacteria and HLA antigens Clinical and Experimental Immunology 1984 57:694-702 PMID:6205801
- Kono, D. H., Park, M. S., Yu, D. T. Y., Granfors, K., Toivanen, A. Absence of lymphotoxic antibodies in patients with Yersinia-induced arthritis, Reiter syndrome and ankylosing-spondylitis Clinical and Experimental Rheumatology 1984 2:303-307 PMID:6335862
- Streicher, H. Z., Gabow, P. A., Moss, A. H., Kono, D., Kaehny, W. D. Syndromes of toluene sniffing in adults Annals of Internal Medicine 1981 94:758-762 DOI:10.7326/0003-4819-94-6-758 PMID:7235417