Jang, Choon-Gon

Faculty Member

Positions

2017 - Visiting Associate Professor of Neurobiology of Addiction, Neuroscience , Scripps Research
2011 - Professor, Sungkyunkwan University
2009 - 2017 Visiting Associate Professor of Neurobiology of Addiction, Committee on the Neurobiology of Addictive Disorders (CNAD) , Scripps Research
2005 - 2011 Associate Professor, Sungkyunkwan University
2001 - 2005 Assistant Professor, Sungkyunkwan University
2000 - 2001 Research Assistant Professor, Hallym University College of Medicine
1996 - 1999 Research Associate, University of Mississippi Medical Center

Contact

cjang@scripps.edu

jang@skku.edu

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- Botanas, C. J., Yoon, S. S., de la Pena, J. B., dela Pena, I. J., Kim, M., Woo, T., Seo, J. W., Jang, C. G., Park, K. T., Lee, Y. H., Lee, Y. S., Kim, H. J., et al. A novel synthetic cathinone, 2-(methylamino)-1-(naphthalen-2-yl) propan-1-one (BMAPN), produced rewarding effects and altered striatal dopamine-related gene expression in mice Behavioural Brain Research 2017 317:494-501 DOI:10.1016/j.bbr.2016.10.016 PMID:27737791
- Botanas, C. J., Yoon, S. S., de la Pena, J. B., dela Pena, I. J., Kim, M., Woo, T., Seo, J. W., Jang, C. G., Park, K. T., Lee, Y. H., Lee, Y. S., Kim, H. J., et al. The abuse potential of two novel synthetic cathinones with modification on the alpha-carbon position, 2-cyclohexyl-2-(methylamino)-1-phenylethanone (MACHP) and 2-(methylamino)-1-phenyloctan-1-one (MAOP), and their effects on dopaminergic activity Pharmacology, Biochemistry and Behavior 2017 153:160-167 DOI:10.1016/j.pbb.2016.12.017 PMID:28063946
- Dang, D. K., Shin, E. J., Nam, Y., Ryoo, S., Jeong, J. H., Jang, C. G., Nabeshima, T., Hong, J. S., Kim, H. C. Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK Journal of Neuroinflammation 2016 13 DOI:10.1186/s12974-016-0478-x
- Shin, E. J., Nam, Y., Lee, J. W., Nguyen, P. K. T., Yoo, J. E., Tran, T. V., Jeong, J. H., Jang, C. G., Oh, Y. J., Youdim, M. B. H., Lee, P. H., Nabeshima, T., et al. N-methyl, N-propynyl-2-phenylethylamine (MPPE), a selegiline analog, attenuates MPTP-induced dopaminergic toxicity with guaranteed behavioral safety: involvement of inhibitions of mitochondrial oxidative burdens and p53 gene-elicited pro-apoptotic change Molecular Neurobiology 2016 53:6251-6269 DOI:10.1007/s12035-015-9527-1 PMID:26563498
- Shin, E. J., Dang, D. K., Tran, H. Q., Nam, Y., Jeong, J. H., Lee, Y. H., Park, K. T., Lee, Y. S., Jang, C. G., Hong, J. S., Nabeshima, T., Kim, H. C. PKCδ knockout mice are protected from para-methoxymethamphetamine-induced mitochondrial stress and associated neurotoxicity in the striatum of mice Neurochemistry International 2016 100:146-158 DOI:10.1016/j.neuint.2016.09.008 PMID:27623093
- Hong, S. I., Kim, M. J., You, I. J., Kwon, S. H., Ma, S. X., Hwang, J. Y., Seo, J. Y., Ko, Y. H., Lee, B. R., Lee, S. Y., Jang, C. G. Phentermine induces conditioned rewarding effects via activation of the PI3K/Akt signaling pathway in the nucleus accumbens Psychopharmacology 2016 233:1405-1413 DOI:10.1007/s00213-016-4231-z PMID:26887589
- Lee, J. Y., Choe, E. S., Yang, C. H., Choi, K. H., Cheong, J. H., Jang, C. G., Seo, J. W., Yoon, S. S. The mGluR5 antagonist MPEP suppresses the expression and reinstatement, but not the acquisition, of the ethanol-conditioned place preference in mice Pharmacology, Biochemistry and Behavior 2016 140:33-38 DOI:10.1016/j.pbb.2015.10.015 PMID:26521964
- Nguyen, X. K. T., Lee, J., Shin, E. J., Dang, D. K., Jeong, J. H., Nguyen, T. T. L., Nam, Y., Cho, H. J., Lee, J. C., Park, D. H., Jang, C. G., Hong, J. S., et al. Liposomal melatonin rescues methamphetamine-elicited mitochondrial burdens, pro-apoptosis, and dopaminergic degeneration through the inhibition PKCδ gene Journal of Pineal Research 2015 58:86-106 DOI:10.1111/jpi.12195 PMID:25407782
- Botanas, C. J., de la Pena, J. B., Dela Pena, I. J., Tampus, R., Yoon, R., Kim, H. J., Lee, Y. S., Jang, C. G., Cheong, J. H. Methoxetamine, a ketamine derivative, produced Conditioned place preference and was self-administered by rats: Evidence of its abuse potential Pharmacology, Biochemistry and Behavior 2015 133:31-36 DOI:10.1016/j.pbb.2015.03.007 PMID:25792291
- Shin, E. J., Shin, S. W., Nguyen, T. T. L., Park, D. H., Wie, M. B., Jang, C. G., Nah, S. Y., Yang, B. W., Ko, S. K., Nabeshima, T., Kim, H. C. Ginsenoside Re rescues methamphetamine-induced oxidative damage, mitochondrial dysfunction, microglial activation, and dopaminergic degeneration by inhibiting the protein kinase Cδ gene Molecular Neurobiology 2014 49:1400-1421 DOI:10.1007/s12035-013-8617-1 PMID:24430743
- Kwon, S. H., Ma, S. X., Lee, S. Y., Jang, C. G. Sulfuretin inhibits 6-hydroxydopamine-induced neuronal cell death via reactive oxygen species-dependent mechanisms in human neuroblastoma SH-SY5Y cells Neurochemistry International 2014 74:53-64 DOI:10.1016/j.neuint.2014.04.016 PMID:24801546
- Nguyen, T. L., Kwon, S. H., Hong, S. L., Ma, S. X., Jung, Y. H., Hwang, J. Y., Kim, H. C., Lee, S. Y., Jang, C. G. Transient receptor potential vanilloid type 1 channel may modulate opioid reward Neuropsychopharmacology 2014 39:2414-2422 DOI:10.1038/npp.2014.90 PMID:24732880 PMCID:PMC4138752
- Jung, Y. H., Ha, R. R., Kwon, S. H., Hong, S. I., Lee, K. H., Kim, S. Y., Lee, S. Y., Jang, C. G. Anxiolytic effects of Julibroside C-1 isolated from Albizzia julibrissin in mice Progress in Neuro-Psychopharmacology & Biological Psychiatry 2013 44:184-192 DOI:10.1016/j.pnpbp.2013.02.012 PMID:23481219
- Park, S. J., Shin, E. J., Min, S. S., An, J., Li, Z., Chung, Y. H., Jeong, J. H., Bach, J. H., Nah, S. Y., Kim, W. K., Jang, C. G., Kim, Y. S., et al. Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging Neuropsychopharmacology 2013 38:1426-1437 DOI:10.1038/npp.2013.39 PMID:23389690 PMCID:PMC3682136
- Lee, S. Y., You, I. J., Kim, M. J., Kwon, S. H., Hong, S. I., Kim, J. H., Jang, M. H., Oh, S. M., Chung, K. H., Lee, S. Y., Jang, C. G. The abuse potential of oxethazaine: effects of oxethazaine on drug-seeking behavior and analysis of its metabolites in plasma and hair in animal models Pharmacology, Biochemistry and Behavior 2013 105:98-104 DOI:10.1016/j.pbb.2013.01.022 PMID:23402942
- Jang, C. G., Whitfield, T., Schulteis, G., Koob, G. F., Wee, S. A dysphoric-like state during early withdrawal from extended access to methamphetamine self-administration in rats Psychopharmacology 2013 225:753-763 DOI:10.1007/s00213-012-2864-0 PMID:23007601 PMCID:PMC3547144
- Jung, Y. H., Kwon, S. H., Hong, S. I., Lee, S. O., Kim, S. Y., Lee, S. Y., Jang, C. G. 5-HT(1A) receptor binding in the dorsal raphe nucleus is implicated in the anxiolytic-like effects of Cinnamomum cassia Pharmacology, Biochemistry and Behavior 2012 103:367-372 DOI:10.1016/j.pbb.2012.09.004 PMID:22982739
- Yoon, S. S., Kim, H. S., Cho, H. Y., Yun, J., Chung, E. Y., Jang, C. G., Kim, K. J., Yang, C. H. Effect of saikosaponin A on maintenance of intravenous morphine self-administration Neuroscience Letters 2012 529:97-101 DOI:10.1016/j.neulet.2012.08.075 PMID:22985511
- You, I. J., Jung, Y. H., Kim, M. J., Kwon, S. H., Hong, S. I., Lee, S. Y., Jang, C. G. Alterations in the emotional and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are mediated by changes in expression of 5-ht1a, gaba(a), and nmda receptors Neuropharmacology 2012 62:1034-1043 DOI:10.1016/j.neuropharm.2011.10.013 PMID:22074644
- Bae, J. W., Choi, C. I., Park, S. H., Jang, C. G., Lee, S. Y. Analytical LC-MS/MS methods for ezetimibe and its application for pharmacokinetic study Journal of Liquid Chromatography & Related Technologies 2012 35:141-152 DOI:10.1080/10826076.2011.597065
- Hong, S. I., Kwon, S. H., Kim, M. J., Ma, S. X., Kwon, J. W., Choi, S. M., Choi, S. I., Kim, S. Y., Lee, S. Y., Jang, C. G. Anxiolytic-like effects of chrysanthemum indicum aqueous extract in mice: Possible involvement of gaba(a) receptors and 5-ht1a receptors Biomolecules & Therapeutics 2012 20:413-417 DOI:10.4062/biomolther.2012.20.4.413 PMID:24009829 PMCID:PMC3762266
- Choi, C. I., Kim, M. J., Chung, E. K., Lee, H. I., Jang, C. G., Bae, J. W., Lee, S. Y. Cyp2c9*3 and *13 alleles significantly affect the pharmacokinetics of irbesartan in healthy korean subjects European Journal of Clinical Pharmacology 2012 68:149-154 DOI:10.1007/s00228-011-1098-0 PMID:21842338
- Choi, C. I., Bae, J. W., Lee, H. I., Jang, C. G., Sohn, U. D., Lee, S. Y. Determination of atomoxetine metabolites in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 2012 885:103-108 DOI:10.1016/j.jchromb.2011.12.023 PMID:22237133
- Lee, S., Kim, J., In, S., Choi, H., Oh, S. M., Jang, C. G., Chung, K. H. Development of a simultaneous analytical method for selected anorectics, methamphetamine, mdma, and their metabolites in hair using lc-ms/ms to prove anorectics abuse Analytical and Bioanalytical Chemistry 2012 403:1385-1394 DOI:10.1007/s00216-012-5950-6 PMID:22460079
- Choi, C. I., Lee, Y. J., Lee, H. I., Kim, B. H., Kim, M. J., Jang, C. G., Bae, J. W., Lee, S. Y. Effects of the slco1b1*15 allele on the pharmacokinetics of pitavastatin Xenobiotica 2012 42:496-501 DOI:10.3109/00498254.2011.632030 PMID:22077103
- Kwon, S. H., Kim, M. J., Ma, S. X., You, I. J., Hwang, J. Y., Oh, J. H., Kim, S. Y., Kim, H. C., Lee, S. Y., Jang, C. G. Eucommia ulmoides oliv. Bark. Protects against hydrogen peroxide-induced neuronal cell death in sh-sy5y cells Journal of Ethnopharmacology 2012 142:337-345 DOI:10.1016/j.jep.2012.04.010 PMID:22735663
- Hwang, S. H., Shin, E. J., Shin, T. J., Lee, B. H., Choi, S. H., Kang, J., Kim, H. J., Kwon, S. H., Jang, C. G., Lee, J. H., Kim, H. C., Nah, S. Y. Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates alzheimer's disease-related neuropathies: Involvement of non-amyloidogenic processing Journal of Alzheimers Disease 2012 31:207-223 DOI:10.3233/jad-2012-120439 PMID:22543851
- Kwon, S. H., Hong, S. I., Jung, Y. H., Kim, M. J., Kim, S. Y., Kim, H. C., Lee, S. Y., Jang, C. G. Lonicera japonica thunb. Protects 6-hydroxydopamine-induced neurotoxicity by inhibiting activation of mapks, pi3k/akt, and nf-kappa b in sh-sy5y cells Food and Chemical Toxicology 2012 50:797-807 DOI:10.1016/j.fct.2011.12.026 PMID:22227216
- Bae, J. W., Jang, C. G., Lee, S. Y. Effects of clopidogrel on the pharmacokinetics of sibutramine and its active metabolites Journal of Clinical Pharmacology 2011 51:1704-1711 DOI:10.1177/0091270010388651 PMID:21209232
- Bae, J. W., Choi, C. I., Jang, C. G., Lee, S. Y. Effects of cyp2c9*1/*13 on the pharmacokinetics and pharmacodynamics of meloxicam British Journal of Clinical Pharmacology 2011 71:550-555 DOI:10.1111/j.1365-2125.2010.03853.x PMID:21395648 PMCID:PMC3080643
- Choi, C. I., Kim, M. J., Jang, C. G., Park, Y. S., Bae, J. W., Lee, S. Y. Effects of the cyp2c9*1/*13 genotype on the pharmacokinetics of lornoxicam Basic & Clinical Pharmacology & Toxicology 2011 109:476-480 DOI:10.1111/j.1742-7843.2011.00751.x PMID:21726410
- Bae, J. W., Choi, C. I., Lee, J. H., Jang, C. G., Chung, M. W., Lee, S. Y. Effects of udp-glucuronosyltransferase polymorphisms on the pharmacokinetics of ezetimibe in healthy subjects European Journal of Clinical Pharmacology 2011 67:39-45 DOI:10.1007/s00228-010-0899-x PMID:20865252
- Bae, J. W., Choi, C. I., Kim, M. J., Oh, D. H., Keum, S. K., Park, J. I., Kim, B. H., Bang, H. K., Oh, S. G., Kang, B. S., Lee, H. I., Lee, Y. J., et al. Frequency of cyp2c9 alleles in koreans and their effects on losartan pharmacokinetics Acta Pharmacologica Sinica 2011 32:1303-1308 DOI:10.1038/aps.2011.100 PMID:21841812 PMCID:PMC4010224
- Shin, E. J., Bach, J. H., Nguyen, T. T. L., Nguyen, X. K. T., Jung, B. D., Oh, K. W., Kim, M. J., Ko, S. K., Jang, C. G., Ali, S. F., Kim, H. C. Gastrodia elata BI attenuates methamphetamine-induced dopaminergic toxicity via inhibiting oxidative burdens Current Neuropharmacology 2011 9:118-121 DOI:10.2174/157015911795016967 PMID:21886575 PMCID:PMC3137164
- Shin, E. J., Bach, J. H., Nguyen, T. T. L., Jung, B. D., Oh, K. W., Kim, M. J., Jang, C. G., Ali, S. F., Ko, S. K., Yang, C. H., Kim, H. C. Gastrodia elata Bl attenuates cocaine-induced conditioned place preference and convulsion, but not behavioral sensitization in mice: importance of GABA(A) receptors Current Neuropharmacology 2011 9:26-29 DOI:10.2174/157015911795017326 PMID:21886556 PMCID:PMC3137195
- Tian, Y. H., Kim, S. H., Lee, S. Y., Jang, C. G. Lactational and postnatal exposure to polychlorinated biphenyls induces sex-specific anxiolytic behavior and cognitive deficit in mice offspring Synapse 2011 65:1032-1041 DOI:10.1002/syn.20934 PMID:21425352
- Kwon, S. H., Kim, J. A., Hong, S. I., Jung, Y. H., Kim, H. C., Lee, S. Y., Jang, C. G. Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of jnk, p38, and erk 1/2 mapks in sh-sy5y cells Neurochemistry International 2011 58:533-541 DOI:10.1016/j.neuint.2011.01.012 PMID:21241762
- Hu, Z., Park, K. S., Han, J. Y., Jang, C. G., Oh, S., Kim, H. C., Yang, C. H., Kim, E. J., Oh, K. W. Markers in morphine- and cocaine-addicted animals Biomolecules & Therapeutics 2011 19:45-51 DOI:10.4062/biomolther.2011.19.1.045
- Lee, K. W., Kim, H. C., Lee, S. Y., Jang, C. G. Methamphetamine-sensitized mice are accompanied by memory impairment and reduction of n-methyl-d-aspartate receptor ligand binding in the prefrontal cortex and hippocampus Neuroscience 2011 178:101-107 DOI:10.1016/j.neuroscience.2011.01.025 PMID:21256196
- Nguyen, T. L., Tian, Y. H., You, I. J., Lee, S. Y., Jang, C. G. Modafinil-induced conditioned place preference via dopaminergic system in mice Synapse 2011 65:733-741 DOI:10.1002/syn.20892 PMID:21157933
- Kwon, S. H., Lee, H. K., Kim, J. A., Hong, S. I., Kim, S. Y., Jo, T. H., Park, Y. I., Lee, C. K., Kim, Y. B., Lee, S. Y., Jang, C. G. Neuroprotective effects of eucommia ulmoides oliv. Bark on amyloid beta(25-35)-induced learning and memory impairments in mice Neuroscience Letters 2011 487:123-127 DOI:10.1016/j.neulet.2010.10.042 PMID:20974223
- Lee, Y. H., Kim, M. J., Choi, C. I., Bae, J. W., Jang, C. G., Lee, S. Y. Retrospective study on antihyperlipidemic efficacy and safety of simvastatin, ezetimibe and their combination in korean adults Archives of Pharmacal Research 2011 34:1331-1337 DOI:10.1007/s12272-011-0813-9 PMID:21910055
- Bae, J. W., Choi, C. I., Jang, C. G., Lee, S. Y. Simultaneous determination of sibutramine and its active metabolites in human plasma by LC-MS/MS and its application to a pharmacokinetic study Biomedical Chromatography 2011 1587 DOI:10.1002/bmc.1587 PMID:21294141
- Kwon, S. H., Hong, S. I., Kim, J. A., Jung, Y. H., Kim, S. Y., Kim, H. C., Lee, S. Y., Jang, C. G. The neuroprotective effects of lonicera japonica thunb. Against hydrogen peroxide-induced apoptosis via phosphorylation of mapks and pi3k/akt in sh-sysy cells Food and Chemical Toxicology 2011 49:1011-1019 DOI:10.1016/j.fct.2011.01.008 PMID:21237235
- Nguyen, T. L., You, I. J., Oh, S., Yang, C. H., Lee, S. Y., Jang, C. G. Assessment of the rewarding effects of dimenhydrinate using the conditioned place preference paradigm in mice Neuroscience Letters 2010 471:38-42 DOI:10.1016/j.neulet.2010.01.005 PMID:20067821
- Nguyen, T. L., Nam, Y. S., Lee, S. Y., Kim, H. C., Jang, C. G. Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice British Journal of Anaesthesia 2010 105:668-674 DOI:10.1093/bja/aeq212 PMID:20719804
- Yoo, J. H., Lee, H. K., Kim, H. C., Lee, S. Y., Jang, C. G. Gaba(a) receptors mediate the attenuating effects of a 5-ht(3) receptor antagonist on methamphetamine-induced behavioral sensitization in mice Synapse 2010 64:274-279 DOI:10.1002/syn.20726 PMID:19953653
- Bae, J. W., Myung, C. S., Choi, C. I., Moon, S. M., Jang, C. G., Lee, S. Y. HPLC assay method for ceftibuten in plasma and its application to pharmacokinetic study Journal of Analytical Chemistry 2010 65:1261-1265 DOI:10.1134/s1061934810120105
- Kwon, S. H., Lee, H. K., Kim, J. A., Hong, S. I., Kim, H. C., Jo, T. H., Park, Y. I., Lee, C. K., Kim, Y. B., Lee, S. Y., Jang, C. G. Neuroprotective effects of chlorogenic acid on scopolamine-induced amnesia via anti-acetylcholinesterase and anti-oxidative activities in mice European Journal of Pharmacology 2010 649:210-217 DOI:10.1016/j.ejphar.2010.09.001 PMID:20854806
- Tian, Y. H., Baek, J. H., Lee, S. Y., Jang, C. G. Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice Synapse 2010 64:432-439 DOI:10.1002/syn.20746 PMID:20169576
- Bae, J. W., Kim, M. J., Jang, C. G., Lee, S. Y. Protective effects of heme oxygenase-1 against mpp(+)-induced cytotoxicity in pc-12 cells Neurological Sciences 2010 31:307-313 DOI:10.1007/s10072-010-0216-6 PMID:20127499
- Tian, Y. H., Lee, S. Y., Kim, H. C., Jang, C. G. Repeated methamphetamine treatment increases expression of trpv1 mrna in the frontal cortex but not in the striatum or hippocampus of mice Neuroscience Letters 2010 472:61-64 DOI:10.1016/j.neulet.2010.01.058 PMID:20122992
- Bae, J. W., Kim, J. H., Choi, C. I., Kim, M. J., Kim, H. J., Byun, S. A., Chang, Y. S., Jang, C. G., Park, Y. S., Lee, S. Y. Effect of cyp2c9*3 allele on the pharmacokinetics of naproxen in korean subjects Archives of Pharmacal Research 2009 32:269-273 DOI:10.1007/s12272-009-1232-z PMID:19280158
- Jin, C. H., Shin, E. J., Park, J. B., Jang, C. G., Li, Z. Y., Kim, M. S., Koo, K. H., Yoon, H. J., Park, S. J., Choi, W. C., Yamada, K., Nabeshima, T., et al. Fustin flavonoid attenuates beta-amyloid (1-42)-induced learning impairment Journal of Neuroscience Research 2009 87:3658-3670 DOI:10.1002/jnr.22159 PMID:19533734
- Bae, J. W., Kim, N. T., Choi, C. I., Kim, M. J., Jang, C. G., Lee, S. Y. HPLC analysis of plasma glipizide and its application to pharmacokinetic study Journal of Liquid Chromatography & Related Technologies 2009 32:1969-1977 DOI:10.1080/10826070903091712
- Kwon, S. H., Kim, H. C., Lee, S. Y., Jang, C. G. Loganin improves learning and memory impairments induced by scopolamine in mice European Journal of Pharmacology 2009 619:44-49 DOI:10.1016/j.ejphar.2009.06.062 PMID:19666019
- Shin, E. J., Jang, C. G., Bing, G. Y., Park, D. H., Oh, C. H., Koo, K. H., Oh, K. W., Yamada, K., Nabeshima, T., Kim, H. C. Prodynorphin gene deficiency potentiates nalbuphine-induced behavioral sensitization and withdrawal syndrome in mice Drug and Alcohol Dependence 2009 104:175-184 DOI:10.1016/j.drugalcdep.2009.05.015 PMID:19559544
- Moon, E., Her, Y., Lee, J. B., Park, J. H., Lee, E. H., Kim, S. H., Oh, M. S., Jang, C. G., Kim, S. Y. The multi-herbal medicine gongjin-dan enhances memory and learning tasks via ngf regulation Neuroscience Letters 2009 466:114-119 DOI:10.1016/j.neulet.2009.09.033 PMID:19788912
- Tian, Y. H., Lee, K. W., You, I. J., Lee, S. Y., Jang, C. G. 7-nitroindazole, nitric oxide synthase inhibitor, attenuates physical dependence on butorphanol in rat Synapse 2008 62:582-589 DOI:10.1002/syn.20530 PMID:18512210
- Myung, C. S., Bae, J. W., Park, Y. S., Kim, M. J., Choi, C. I., Song, Y., Sa, J. H., Jang, C. G., Lee, S. Y. Analytical HPLC method validation of amiloride and its pharmacokinetic study in humans Journal of Liquid Chromatography & Related Technologies 2008 31:2455-2466 DOI:10.1080/10826070802319693
- Lee, K. W., Tian, Y. H., You, I. J., Kwon, S. H., Ha, R. R., Lee, S. Y., Kim, H. C., Jang, C. G. Blockade of m1 muscarinic acetylcholine receptors modulates the methamphetamine-induced psychomotor stimulant effect Neuroscience 2008 153:1235-1244 DOI:10.1016/j.neuroscience.2008.02.021 PMID:18455881
- Yoo, J. H., Nam, Y. S., Lee, S. Y., Jang, C. G. Dopamine neurotransmission is involved in the attenuating effects of 5-ht3 receptor antagonist mdl 72222 on acute methamphetamine-induced locomotor hyperactivity in mice Synapse 2008 62:8-13 DOI:10.1002/syn.20461 PMID:17948891
- Kwon, S. H., Ha, R. R., Lee, S. Y., Jang, C. G. Involvement of pCREB expression in inhibitory effects of Coptis japonica on morphine-induced psychological dependence Biomolecules & Therapeutics 2008 16:113-117 DOI:10.4062/biomolther.2008.16.2.113
- Yang, M. H., Kim, S., Jung, M. S., Shim, J. H., Ryu, N. K., Yook, Y. J., Jang, C. G., Bahk, Y. Y., Kim, K. W., Park, J. H. Proteomic analysis of methamphetamine-induced reinforcement processes within the mesolimbic dopamine system Addiction Biology 2008 13:287-294 DOI:10.1111/j.1369-1600.2007.00090.x PMID:18279499
- Kim, J. H., Kim, S. Y., Lee, S. Y., Jang, C. G. Antidepressant-like effects of albizzia julibrissin in mice: Involvement of the 5-ht1a receptor system Pharmacology, Biochemistry and Behavior 2007 87:41-47 DOI:10.1016/j.pbb.2007.03.018 PMID:17477962
- Yoon, B. H., Jung, J. W., Lee, J. J., Cho, Y. W., Jang, C. G., Jin, C., Oh, T. H., Ryu, J. H. Anxiolytic-like effects of sinapic acid in mice Life Sciences 2007 81:234-240 DOI:10.1016/j.lfs.2007.05.007 PMID:17570441
- Bae, J. W., Kim, M. J., Park, Y. S., Myung, C. S., Jang, C. G., Lee, S. Y. Considerable interindividual variation in the pharmacokinetics of tolperisone hcl International Journal of Clinical Pharmacology and Therapeutics 2007 45:110-113 PMID:17323790
- Bae, J. W., Kim, M. J., Jang, C. G., Lee, S. Y. Determination of meloxicam in human plasma using a hplc method with uv detection and its application to a pharmacokinetic study Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 2007 859:69-73 DOI:10.1016/j.jchromb.2007.09.004 PMID:17921074
- Shin, E. J., Jeong, J. H., Kim, H. J., Jang, C. G., Yamada, K., Nabeshima, T., Kim, Y. C. Exposure to extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine d-1-like receptors in mice Journal of Pharmacological Sciences 2007 105:367-371 DOI:10.1254/jphs.SC0070348 PMID:18094524
- Lee, B. H., Lee, J. H., Lee, S. M., Jeong, S. M., Yoon, I. S., Choi, S. H., Pyo, M. K., Rhim, H., Jang, C. G., Kim, H. C., Park, C. S., Lee, B. C., et al. Identification of ginsenoside interaction sites in 5-ht3a receptors Neuropharmacology 2007 52:1139-1150 DOI:10.1016/j.neuropharm.2006.12.001 PMID:17257631
- Yu, H. S., Lee, S. Y., Jang, C. G. Involvement of 5-ht1a and gaba(a) receptors in the anxiolytic-like effects of cinnamomum cassia in mice Pharmacology, Biochemistry and Behavior 2007 87:164-170 DOI:10.1016/j.pbb.2007.04.013 PMID:17512974
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- Bae, J. W., Kim, H. K., Kim, J. H., Yang, S. I., Kim, M. J., Jang, C. G., Park, Y. S., Lee, S. Y. Allele and genotype frequencies of cyp2c9 in a korean population British Journal of Clinical Pharmacology 2005 60:418-422 DOI:10.1111/j.1365-2125.2005.02448.x PMID:16187974 PMCID:PMC1884827
- Lee, J. H., Jeong, S. M., Kim, J. H., Lee, B. H., Yoon, I. S., Choi, S. H., Kim, D. H., Rhim, H., Jang, C. G., Kim, S. S., Kim, J. I., Nah, S. Y., et al. Characteristics of ginsenoside rg(3)-mediated brain na+ current inhibition Molecular Pharmacology 2005 68:1114-1126 DOI:10.1124/mol.105.015115 PMID:16014805
- Jeong, S. M., Park, H. K., Yoon, I. S., Lee, J. H., Kim, J. H., Jang, C. G., Lee, C. J., Nah, S. Y. Cloning and expression of ca2+-activated chloride channel from rat brain Biochemical and Biophysical Research Communications 2005 334:569-576 DOI:10.1016/j.bbrc.2005.06.122 PMID:16023076
- Jung, J. W., Cho, J. H., Ahn, N. Y., Oh, H. R., Kim, S. Y., Jang, C. G., Ryu, J. H. Effect of chronic albizzia julibrissin treatment on 5-hydroxytryptamine(1a) receptors in rat brain Pharmacology, Biochemistry and Behavior 2005 81:205-210 DOI:10.1016/j.pbb.2005.03.014 PMID:15894080
- Lee, S. Y., Jang, C. G. Increases in h-3 -alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor binding and mrna expression of ampa-sensitive glutamate receptor a (glur-a) subunits in rats withdrawn from butorphanol Journal of Toxicology and Environmental Health-Part A-Current Issues 2005 68:2163-2174 DOI:10.1080/15287390500177263 PMID:16326431
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- Kim, H. C., Shin, E. J., Jang, C. G., Lee, M. K., Eun, J. S., Hong, J. T., Oh, K. W. Pharmacological action of panax ginseng on the behavioral toxicities induced by psychotropic agents Archives of Pharmacal Research 2005 28:995-1001 DOI:10.1007/bf02977391 PMID:16212227
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- Yoo, J. H., Lee, S. Y., Loh, H. H., Ho, I. K., Jang, C. G. Altered emotional behaviors and the expression of 5-ht1a and m-1 muscarinic receptors in mu-opioid receptor knockout mice Synapse 2004 54:72-82 DOI:10.1002/syn.20067 PMID:15352132
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- Jang, C. G., Kang, M., Cho, J. H., Lee, S. B., Kim, H., Park, S., Lee, J., Park, S. K., Hong, M., Shin, M. K., Shim, I. S., Bae, H. Nelumbinis semen reverse's a decrease in 5-ht1a receptor binding induced by chronic mild stress, a depression-like symptom Archives of Pharmacal Research 2004 27:1065-1072 DOI:10.1007/bf02975433 PMID:15554266
- Kwon, Y. S., Nabeshima, T., Shin, E. J., Chun, W., Jhoo, J. H., Jhoo, W. K., Wie, N. B., Jang, C. G., Chung, H., Sung, Y. E., Kim, H. C. Pap 9704, a korean herbal medicine attenuates methamphetamine-induced hyperlocomotion via adenosine a(2a) receptor stimulation in mice Biological & Pharmaceutical Bulletin 2004 27:906-909 DOI:10.1248/bpb.27.906 PMID:15187444
- Yang, S. I., Park, H. Y., Lee, S. H., Lee, S. J., Han, O. Y., Lim, S. C., Jang, C. G., Lee, W. S., Shin, Y. H., Kim, J. J., Lee, S. Y. Transdermal eperisone elicits more potent and longer-lasting muscle relaxation than oral eperisone Pharmacology 2004 71:150-156 DOI:10.1159/000077449 PMID:15161997
- Yoo, J. H., Yang, E. M., Lee, S. Y., Loh, H. H., Ho, I. K., Jang, C. G. Differential effects of morphine and cocaine on locomotor activity and sensitization in mu-opioid receptor knockout mice Neuroscience Letters 2003 344:37-40 DOI:10.1016/s0304-3940(03)00410-5 PMID:12781916
- Lee, S. Y., Song, D. K., Jang, C. G. Effects of coptis japonica on morphine-induced conditioned place preference in mice Archives of Pharmacal Research 2003 26:540-544 DOI:10.1007/bf02976878 PMID:12934646
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- Lee, S. H., Jang, C. G., Lee, S. Y. Tyrosine kinase is involved in hemin-induced pyresis Archives of Pharmacal Research 2003 26:411-415 DOI:10.1007/bf02976699 PMID:12785738
- Jang, C. G., Lee, S. J., Yang, S. I., Kim, J. H., Sohn, U. D., Lee, S. Y. Carbon monoxide as a novel central pyrogenic mediator Archives of Pharmacal Research 2002 25:343-348 DOI:10.1007/bf02976637 PMID:12135108
- Jang, C. G., Lee, S. Y., Lee, H. K., Suh, H. W., Song, D. K. Time courses of pcreb expression after dopaminergic stimulation by apomorphine in mouse brain Archives of Pharmacal Research 2002 25:370-374 DOI:10.1007/bf02976641 PMID:12135112
- Jang, C. G., Lee, S. Y., Park, Y., Ma, T. G., Loh, H. H., Ho, I. K. Differential effects of morphine, dpdpe, and u-50488 on apomorphine-induced climbing behavior in mu-opioid receptor knockout mice Molecular Brain Research 2001 94:197-199 DOI:10.1016/s0169-328x(01)00227-3 PMID:11597780
- Lee, H. U., Lee, H. J., Park, H. Y., Lee, S. H., Jang, C. G., Lee, S. Y. Effects of heme oxygenase system on the cyclooxygenase in the primary cultured hypothalamic cells Archives of Pharmacal Research 2001 24:607-612 DOI:10.1007/bf02975174 PMID:11794544
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