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Jang, Choon-Gon
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Jang, Choon-Gon

Faculty Member
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Positions

  • 2017 - Visiting Associate Professor of Neurobiology of Addiction, Neuroscience , Scripps Research
  • 2011 - Professor, Sungkyunkwan University
  • 2009 - 2017 Visiting Associate Professor of Neurobiology of Addiction, Committee on the Neurobiology of Addictive Disorders (CNAD) , Scripps Research
  • 2005 - 2011 Associate Professor, Sungkyunkwan University
  • 2001 - 2005 Assistant Professor, Sungkyunkwan University
  • 2000 - 2001 Research Assistant Professor, Hallym University College of Medicine
  • 1996 - 1999 Research Associate, University of Mississippi Medical Center

Contact

  • cjang@scripps.edu
  • jang@skku.edu
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Publications

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    • Botanas, C. J., Yoon, S. S., de la Pena, J. B., dela Pena, I. J., Kim, M., Woo, T., Seo, J. W., Jang, C. G., Park, K. T., Lee, Y. H., Lee, Y. S., Kim, H. J., et al. The abuse potential of two novel synthetic cathinones with modification on the alpha-carbon position, 2-cyclohexyl-2-(methylamino)-1-phenylethanone (MACHP) and 2-(methylamino)-1-phenyloctan-1-one (MAOP), and their effects on dopaminergic activity Pharmacology, Biochemistry and Behavior  2017 153:160-167  DOI:10.1016/j.pbb.2016.12.017  PMID:28063946
    • Botanas, C. J., Yoon, S. S., de la Pena, J. B., dela Pena, I. J., Kim, M., Woo, T., Seo, J. W., Jang, C. G., Park, K. T., Lee, Y. H., Lee, Y. S., Kim, H. J., et al. A novel synthetic cathinone, 2-(methylamino)-1-(naphthalen-2-yl) propan-1-one (BMAPN), produced rewarding effects and altered striatal dopamine-related gene expression in mice Behavioural Brain Research  2017 317:494-501  DOI:10.1016/j.bbr.2016.10.016  PMID:27737791
    • Shin, E. J., Nam, Y., Lee, J. W., Nguyen, P. K. T., Yoo, J. E., Tran, T. V., Jeong, J. H., Jang, C. G., Oh, Y. J., Youdim, M. B. H., Lee, P. H., Nabeshima, T., et al. N-methyl, N-propynyl-2-phenylethylamine (MPPE), a selegiline analog, attenuates MPTP-induced dopaminergic toxicity with guaranteed behavioral safety: involvement of inhibitions of mitochondrial oxidative burdens and p53 gene-elicited pro-apoptotic change Molecular Neurobiology  2016 53:6251-6269  DOI:10.1007/s12035-015-9527-1  PMID:26563498
    • Shin, E. J., Dang, D. K., Tran, H. Q., Nam, Y., Jeong, J. H., Lee, Y. H., Park, K. T., Lee, Y. S., Jang, C. G., Hong, J. S., Nabeshima, T., Kim, H. C. PKCδ knockout mice are protected from para-methoxymethamphetamine-induced mitochondrial stress and associated neurotoxicity in the striatum of mice Neurochemistry International  2016 100:146-158  DOI:10.1016/j.neuint.2016.09.008  PMID:27623093
    • Hong, S. I., Kim, M. J., You, I. J., Kwon, S. H., Ma, S. X., Hwang, J. Y., Seo, J. Y., Ko, Y. H., Lee, B. R., Lee, S. Y., Jang, C. G. Phentermine induces conditioned rewarding effects via activation of the PI3K/Akt signaling pathway in the nucleus accumbens Psychopharmacology  2016 233:1405-1413  DOI:10.1007/s00213-016-4231-z  PMID:26887589
    • Dang, D. K., Shin, E. J., Nam, Y., Ryoo, S., Jeong, J. H., Jang, C. G., Nabeshima, T., Hong, J. S., Kim, H. C. Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK Journal of Neuroinflammation  2016 13  DOI:10.1186/s12974-016-0478-x
    • Lee, J. Y., Choe, E. S., Yang, C. H., Choi, K. H., Cheong, J. H., Jang, C. G., Seo, J. W., Yoon, S. S. The mGluR5 antagonist MPEP suppresses the expression and reinstatement, but not the acquisition, of the ethanol-conditioned place preference in mice Pharmacology, Biochemistry and Behavior  2016 140:33-38  DOI:10.1016/j.pbb.2015.10.015  PMID:26521964
    • Botanas, C. J., de la Pena, J. B., Dela Pena, I. J., Tampus, R., Yoon, R., Kim, H. J., Lee, Y. S., Jang, C. G., Cheong, J. H. Methoxetamine, a ketamine derivative, produced Conditioned place preference and was self-administered by rats: Evidence of its abuse potential Pharmacology, Biochemistry and Behavior  2015 133:31-36  DOI:10.1016/j.pbb.2015.03.007  PMID:25792291
    • Nguyen, X. K. T., Lee, J., Shin, E. J., Dang, D. K., Jeong, J. H., Nguyen, T. T. L., Nam, Y., Cho, H. J., Lee, J. C., Park, D. H., Jang, C. G., Hong, J. S., et al. Liposomal melatonin rescues methamphetamine-elicited mitochondrial burdens, pro-apoptosis, and dopaminergic degeneration through the inhibition PKCδ gene Journal of Pineal Research  2015 58:86-106  DOI:10.1111/jpi.12195  PMID:25407782
    • Nguyen, T. L., Kwon, S. H., Hong, S. L., Ma, S. X., Jung, Y. H., Hwang, J. Y., Kim, H. C., Lee, S. Y., Jang, C. G. Transient receptor potential vanilloid type 1 channel may modulate opioid reward Neuropsychopharmacology  2014 39:2414-2422  DOI:10.1038/npp.2014.90  PMID:24732880  PMCID:PMC4138752
    • Kwon, S. H., Ma, S. X., Lee, S. Y., Jang, C. G. Sulfuretin inhibits 6-hydroxydopamine-induced neuronal cell death via reactive oxygen species-dependent mechanisms in human neuroblastoma SH-SY5Y cells Neurochemistry International  2014 74:53-64  DOI:10.1016/j.neuint.2014.04.016  PMID:24801546
    • Shin, E. J., Shin, S. W., Nguyen, T. T. L., Park, D. H., Wie, M. B., Jang, C. G., Nah, S. Y., Yang, B. W., Ko, S. K., Nabeshima, T., Kim, H. C. Ginsenoside Re rescues methamphetamine-induced oxidative damage, mitochondrial dysfunction, microglial activation, and dopaminergic degeneration by inhibiting the protein kinase Cδ gene Molecular Neurobiology  2014 49:1400-1421  DOI:10.1007/s12035-013-8617-1  PMID:24430743
    • Jung, Y. H., Ha, R. R., Kwon, S. H., Hong, S. I., Lee, K. H., Kim, S. Y., Lee, S. Y., Jang, C. G. Anxiolytic effects of Julibroside C-1 isolated from Albizzia julibrissin in mice Progress in Neuro-Psychopharmacology & Biological Psychiatry  2013 44:184-192  DOI:10.1016/j.pnpbp.2013.02.012  PMID:23481219
    • Park, S. J., Shin, E. J., Min, S. S., An, J., Li, Z., Chung, Y. H., Jeong, J. H., Bach, J. H., Nah, S. Y., Kim, W. K., Jang, C. G., Kim, Y. S., et al. Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging Neuropsychopharmacology  2013 38:1426-1437  DOI:10.1038/npp.2013.39  PMID:23389690  PMCID:PMC3682136
    • Lee, S. Y., You, I. J., Kim, M. J., Kwon, S. H., Hong, S. I., Kim, J. H., Jang, M. H., Oh, S. M., Chung, K. H., Lee, S. Y., Jang, C. G. The abuse potential of oxethazaine: effects of oxethazaine on drug-seeking behavior and analysis of its metabolites in plasma and hair in animal models Pharmacology, Biochemistry and Behavior  2013 105:98-104  DOI:10.1016/j.pbb.2013.01.022  PMID:23402942
    • Jang, C. G., Whitfield, T., Schulteis, G., Koob, G. F., Wee, S. A dysphoric-like state during early withdrawal from extended access to methamphetamine self-administration in rats Psychopharmacology  2013 225:753-763  DOI:10.1007/s00213-012-2864-0  PMID:23007601  PMCID:PMC3547144
    • Jung, Y. H., Kwon, S. H., Hong, S. I., Lee, S. O., Kim, S. Y., Lee, S. Y., Jang, C. G. 5-HT(1A) receptor binding in the dorsal raphe nucleus is implicated in the anxiolytic-like effects of Cinnamomum cassia Pharmacology, Biochemistry and Behavior  2012 103:367-372  DOI:10.1016/j.pbb.2012.09.004  PMID:22982739
    • Yoon, S. S., Kim, H. S., Cho, H. Y., Yun, J., Chung, E. Y., Jang, C. G., Kim, K. J., Yang, C. H. Effect of saikosaponin A on maintenance of intravenous morphine self-administration Neuroscience Letters  2012 529:97-101  DOI:10.1016/j.neulet.2012.08.075  PMID:22985511
    • Hong, S. I., Kwon, S. H., Kim, M. J., Ma, S. X., Kwon, J. W., Choi, S. M., Choi, S. I., Kim, S. Y., Lee, S. Y., Jang, C. G. Anxiolytic-like effects of chrysanthemum indicum aqueous extract in mice: Possible involvement of gaba(a) receptors and 5-ht1a receptors Biomolecules & Therapeutics  2012 20:413-417  DOI:10.4062/biomolther.2012.20.4.413  PMID:24009829  PMCID:PMC3762266
    • Kwon, S. H., Kim, M. J., Ma, S. X., You, I. J., Hwang, J. Y., Oh, J. H., Kim, S. Y., Kim, H. C., Lee, S. Y., Jang, C. G. Eucommia ulmoides oliv. Bark. Protects against hydrogen peroxide-induced neuronal cell death in sh-sy5y cells Journal of Ethnopharmacology  2012 142:337-345  DOI:10.1016/j.jep.2012.04.010  PMID:22735663
    • Lee, S., Kim, J., In, S., Choi, H., Oh, S. M., Jang, C. G., Chung, K. H. Development of a simultaneous analytical method for selected anorectics, methamphetamine, mdma, and their metabolites in hair using lc-ms/ms to prove anorectics abuse Analytical and Bioanalytical Chemistry  2012 403:1385-1394  DOI:10.1007/s00216-012-5950-6  PMID:22460079
    • Choi, C. I., Lee, Y. J., Lee, H. I., Kim, B. H., Kim, M. J., Jang, C. G., Bae, J. W., Lee, S. Y. Effects of the slco1b1*15 allele on the pharmacokinetics of pitavastatin Xenobiotica  2012 42:496-501  DOI:10.3109/00498254.2011.632030  PMID:22077103
    • Kwon, S. H., Hong, S. I., Jung, Y. H., Kim, M. J., Kim, S. Y., Kim, H. C., Lee, S. Y., Jang, C. G. Lonicera japonica thunb. Protects 6-hydroxydopamine-induced neurotoxicity by inhibiting activation of mapks, pi3k/akt, and nf-kappa b in sh-sy5y cells Food and Chemical Toxicology  2012 50:797-807  DOI:10.1016/j.fct.2011.12.026  PMID:22227216
    • Choi, C. I., Bae, J. W., Lee, H. I., Jang, C. G., Sohn, U. D., Lee, S. Y. Determination of atomoxetine metabolites in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences  2012 885:103-108  DOI:10.1016/j.jchromb.2011.12.023  PMID:22237133
    • You, I. J., Jung, Y. H., Kim, M. J., Kwon, S. H., Hong, S. I., Lee, S. Y., Jang, C. G. Alterations in the emotional and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are mediated by changes in expression of 5-ht1a, gaba(a), and nmda receptors Neuropharmacology  2012 62:1034-1043  DOI:10.1016/j.neuropharm.2011.10.013  PMID:22074644
    • Choi, C. I., Kim, M. J., Chung, E. K., Lee, H. I., Jang, C. G., Bae, J. W., Lee, S. Y. Cyp2c9*3 and *13 alleles significantly affect the pharmacokinetics of irbesartan in healthy korean subjects European Journal of Clinical Pharmacology  2012 68:149-154  DOI:10.1007/s00228-011-1098-0  PMID:21842338
    • Bae, J. W., Choi, C. I., Park, S. H., Jang, C. G., Lee, S. Y. Analytical LC-MS/MS methods for ezetimibe and its application for pharmacokinetic study Journal of Liquid Chromatography & Related Technologies  2012 35:141-152  DOI:10.1080/10826076.2011.597065
    • Hwang, S. H., Shin, E. J., Shin, T. J., Lee, B. H., Choi, S. H., Kang, J., Kim, H. J., Kwon, S. H., Jang, C. G., Lee, J. H., Kim, H. C., Nah, S. Y. Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates alzheimer's disease-related neuropathies: Involvement of non-amyloidogenic processing Journal of Alzheimers Disease  2012 31:207-223  DOI:10.3233/jad-2012-120439  PMID:22543851
    • Bae, J. W., Jang, C. G., Lee, S. Y. Effects of clopidogrel on the pharmacokinetics of sibutramine and its active metabolites Journal of Clinical Pharmacology  2011 51:1704-1711  DOI:10.1177/0091270010388651  PMID:21209232
    • Choi, C. I., Kim, M. J., Jang, C. G., Park, Y. S., Bae, J. W., Lee, S. Y. Effects of the cyp2c9*1/*13 genotype on the pharmacokinetics of lornoxicam Basic & Clinical Pharmacology & Toxicology  2011 109:476-480  DOI:10.1111/j.1742-7843.2011.00751.x  PMID:21726410
    • Bae, J. W., Choi, C. I., Jang, C. G., Lee, S. Y. Simultaneous determination of sibutramine and its active metabolites in human plasma by LC-MS/MS and its application to a pharmacokinetic study Biomedical Chromatography  2011 1587  DOI:10.1002/bmc.1587  PMID:21294141
    • Bae, J. W., Choi, C. I., Kim, M. J., Oh, D. H., Keum, S. K., Park, J. I., Kim, B. H., Bang, H. K., Oh, S. G., Kang, B. S., Lee, H. I., Lee, Y. J., et al. Frequency of cyp2c9 alleles in koreans and their effects on losartan pharmacokinetics Acta Pharmacologica Sinica  2011 32:1303-1308  DOI:10.1038/aps.2011.100  PMID:21841812  PMCID:PMC4010224
    • Tian, Y. H., Kim, S. H., Lee, S. Y., Jang, C. G. Lactational and postnatal exposure to polychlorinated biphenyls induces sex-specific anxiolytic behavior and cognitive deficit in mice offspring Synapse  2011 65:1032-1041  DOI:10.1002/syn.20934  PMID:21425352
    • Nguyen, T. L., Tian, Y. H., You, I. J., Lee, S. Y., Jang, C. G. Modafinil-induced conditioned place preference via dopaminergic system in mice Synapse  2011 65:733-741  DOI:10.1002/syn.20892  PMID:21157933
    • Lee, Y. H., Kim, M. J., Choi, C. I., Bae, J. W., Jang, C. G., Lee, S. Y. Retrospective study on antihyperlipidemic efficacy and safety of simvastatin, ezetimibe and their combination in korean adults Archives of Pharmacal Research  2011 34:1331-1337  DOI:10.1007/s12272-011-0813-9  PMID:21910055
    • Bae, J. W., Choi, C. I., Jang, C. G., Lee, S. Y. Effects of cyp2c9*1/*13 on the pharmacokinetics and pharmacodynamics of meloxicam British Journal of Clinical Pharmacology  2011 71:550-555  DOI:10.1111/j.1365-2125.2010.03853.x  PMID:21395648  PMCID:PMC3080643
    • Kwon, S. H., Hong, S. I., Kim, J. A., Jung, Y. H., Kim, S. Y., Kim, H. C., Lee, S. Y., Jang, C. G. The neuroprotective effects of lonicera japonica thunb. Against hydrogen peroxide-induced apoptosis via phosphorylation of mapks and pi3k/akt in sh-sysy cells Food and Chemical Toxicology  2011 49:1011-1019  DOI:10.1016/j.fct.2011.01.008  PMID:21237235
    • Lee, K. W., Kim, H. C., Lee, S. Y., Jang, C. G. Methamphetamine-sensitized mice are accompanied by memory impairment and reduction of n-methyl-d-aspartate receptor ligand binding in the prefrontal cortex and hippocampus Neuroscience  2011 178:101-107  DOI:10.1016/j.neuroscience.2011.01.025  PMID:21256196
    • Shin, E. J., Bach, J. H., Nguyen, T. T. L., Jung, B. D., Oh, K. W., Kim, M. J., Jang, C. G., Ali, S. F., Ko, S. K., Yang, C. H., Kim, H. C. Gastrodia elata Bl attenuates cocaine-induced conditioned place preference and convulsion, but not behavioral sensitization in mice: importance of GABA(A) receptors Current Neuropharmacology  2011 9:26-29  DOI:10.2174/157015911795017326  PMID:21886556  PMCID:PMC3137195
    • Kwon, S. H., Kim, J. A., Hong, S. I., Jung, Y. H., Kim, H. C., Lee, S. Y., Jang, C. G. Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of jnk, p38, and erk 1/2 mapks in sh-sy5y cells Neurochemistry International  2011 58:533-541  DOI:10.1016/j.neuint.2011.01.012  PMID:21241762
    • Hu, Z., Park, K. S., Han, J. Y., Jang, C. G., Oh, S., Kim, H. C., Yang, C. H., Kim, E. J., Oh, K. W. Markers in morphine- and cocaine-addicted animals Biomolecules & Therapeutics  2011 19:45-51  DOI:10.4062/biomolther.2011.19.1.045
    • Kwon, S. H., Lee, H. K., Kim, J. A., Hong, S. I., Kim, S. Y., Jo, T. H., Park, Y. I., Lee, C. K., Kim, Y. B., Lee, S. Y., Jang, C. G. Neuroprotective effects of eucommia ulmoides oliv. Bark on amyloid beta(25-35)-induced learning and memory impairments in mice Neuroscience Letters  2011 487:123-127  DOI:10.1016/j.neulet.2010.10.042  PMID:20974223
    • Bae, J. W., Choi, C. I., Lee, J. H., Jang, C. G., Chung, M. W., Lee, S. Y. Effects of udp-glucuronosyltransferase polymorphisms on the pharmacokinetics of ezetimibe in healthy subjects European Journal of Clinical Pharmacology  2011 67:39-45  DOI:10.1007/s00228-010-0899-x  PMID:20865252
    • Shin, E. J., Bach, J. H., Nguyen, T. T. L., Nguyen, X. K. T., Jung, B. D., Oh, K. W., Kim, M. J., Ko, S. K., Jang, C. G., Ali, S. F., Kim, H. C. Gastrodia elata BI attenuates methamphetamine-induced dopaminergic toxicity via inhibiting oxidative burdens Current Neuropharmacology  2011 9:118-121  DOI:10.2174/157015911795016967  PMID:21886575  PMCID:PMC3137164
    • Kwon, S. H., Lee, H. K., Kim, J. A., Hong, S. I., Kim, H. C., Jo, T. H., Park, Y. I., Lee, C. K., Kim, Y. B., Lee, S. Y., Jang, C. G. Neuroprotective effects of chlorogenic acid on scopolamine-induced amnesia via anti-acetylcholinesterase and anti-oxidative activities in mice European Journal of Pharmacology  2010 649:210-217  DOI:10.1016/j.ejphar.2010.09.001  PMID:20854806
    • Bae, J. W., Myung, C. S., Choi, C. I., Moon, S. M., Jang, C. G., Lee, S. Y. HPLC assay method for ceftibuten in plasma and its application to pharmacokinetic study Journal of Analytical Chemistry  2010 65:1261-1265  DOI:10.1134/s1061934810120105
    • Nguyen, T. L., Nam, Y. S., Lee, S. Y., Kim, H. C., Jang, C. G. Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice British Journal of Anaesthesia  2010 105:668-674  DOI:10.1093/bja/aeq212  PMID:20719804
    • Tian, Y. H., Baek, J. H., Lee, S. Y., Jang, C. G. Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice Synapse  2010 64:432-439  DOI:10.1002/syn.20746  PMID:20169576
    • Bae, J. W., Kim, M. J., Jang, C. G., Lee, S. Y. Protective effects of heme oxygenase-1 against mpp(+)-induced cytotoxicity in pc-12 cells Neurological Sciences  2010 31:307-313  DOI:10.1007/s10072-010-0216-6  PMID:20127499
    • Yoo, J. H., Lee, H. K., Kim, H. C., Lee, S. Y., Jang, C. G. Gaba(a) receptors mediate the attenuating effects of a 5-ht(3) receptor antagonist on methamphetamine-induced behavioral sensitization in mice Synapse  2010 64:274-279  DOI:10.1002/syn.20726  PMID:19953653
    • Tian, Y. H., Lee, S. Y., Kim, H. C., Jang, C. G. Repeated methamphetamine treatment increases expression of trpv1 mrna in the frontal cortex but not in the striatum or hippocampus of mice Neuroscience Letters  2010 472:61-64  DOI:10.1016/j.neulet.2010.01.058  PMID:20122992
    • Nguyen, T. L., You, I. J., Oh, S., Yang, C. H., Lee, S. Y., Jang, C. G. Assessment of the rewarding effects of dimenhydrinate using the conditioned place preference paradigm in mice Neuroscience Letters  2010 471:38-42  DOI:10.1016/j.neulet.2010.01.005  PMID:20067821
    • Moon, E., Her, Y., Lee, J. B., Park, J. H., Lee, E. H., Kim, S. H., Oh, M. S., Jang, C. G., Kim, S. Y. The multi-herbal medicine gongjin-dan enhances memory and learning tasks via ngf regulation Neuroscience Letters  2009 466:114-119  DOI:10.1016/j.neulet.2009.09.033  PMID:19788912
    • Jin, C. H., Shin, E. J., Park, J. B., Jang, C. G., Li, Z. Y., Kim, M. S., Koo, K. H., Yoon, H. J., Park, S. J., Choi, W. C., Yamada, K., Nabeshima, T., et al. Fustin flavonoid attenuates beta-amyloid (1-42)-induced learning impairment Journal of Neuroscience Research  2009 87:3658-3670  DOI:10.1002/jnr.22159  PMID:19533734
    • Kwon, S. H., Kim, H. C., Lee, S. Y., Jang, C. G. Loganin improves learning and memory impairments induced by scopolamine in mice European Journal of Pharmacology  2009 619:44-49  DOI:10.1016/j.ejphar.2009.06.062  PMID:19666019
    • Shin, E. J., Jang, C. G., Bing, G. Y., Park, D. H., Oh, C. H., Koo, K. H., Oh, K. W., Yamada, K., Nabeshima, T., Kim, H. C. Prodynorphin gene deficiency potentiates nalbuphine-induced behavioral sensitization and withdrawal syndrome in mice Drug and Alcohol Dependence  2009 104:175-184  DOI:10.1016/j.drugalcdep.2009.05.015  PMID:19559544
    • Bae, J. W., Kim, J. H., Choi, C. I., Kim, M. J., Kim, H. J., Byun, S. A., Chang, Y. S., Jang, C. G., Park, Y. S., Lee, S. Y. Effect of cyp2c9*3 allele on the pharmacokinetics of naproxen in korean subjects Archives of Pharmacal Research  2009 32:269-273  DOI:10.1007/s12272-009-1232-z  PMID:19280158
    • Bae, J. W., Kim, N. T., Choi, C. I., Kim, M. J., Jang, C. G., Lee, S. Y. HPLC analysis of plasma glipizide and its application to pharmacokinetic study Journal of Liquid Chromatography & Related Technologies  2009 32:1969-1977  DOI:10.1080/10826070903091712
    • Yang, M. H., Kim, S., Jung, M. S., Shim, J. H., Ryu, N. K., Yook, Y. J., Jang, C. G., Bahk, Y. Y., Kim, K. W., Park, J. H. Proteomic analysis of methamphetamine-induced reinforcement processes within the mesolimbic dopamine system Addiction Biology  2008 13:287-294  DOI:10.1111/j.1369-1600.2007.00090.x  PMID:18279499
    • Tian, Y. H., Lee, K. W., You, I. J., Lee, S. Y., Jang, C. G. 7-nitroindazole, nitric oxide synthase inhibitor, attenuates physical dependence on butorphanol in rat Synapse  2008 62:582-589  DOI:10.1002/syn.20530  PMID:18512210
    • Lee, K. W., Tian, Y. H., You, I. J., Kwon, S. H., Ha, R. R., Lee, S. Y., Kim, H. C., Jang, C. G. Blockade of m1 muscarinic acetylcholine receptors modulates the methamphetamine-induced psychomotor stimulant effect Neuroscience  2008 153:1235-1244  DOI:10.1016/j.neuroscience.2008.02.021  PMID:18455881
    • Kwon, S. H., Ha, R. R., Lee, S. Y., Jang, C. G. Involvement of pCREB expression in inhibitory effects of Coptis japonica on morphine-induced psychological dependence Biomolecules & Therapeutics  2008 16:113-117  DOI:10.4062/biomolther.2008.16.2.113
    • Myung, C. S., Bae, J. W., Park, Y. S., Kim, M. J., Choi, C. I., Song, Y., Sa, J. H., Jang, C. G., Lee, S. Y. Analytical HPLC method validation of amiloride and its pharmacokinetic study in humans Journal of Liquid Chromatography & Related Technologies  2008 31:2455-2466  DOI:10.1080/10826070802319693
    • Yoo, J. H., Nam, Y. S., Lee, S. Y., Jang, C. G. Dopamine neurotransmission is involved in the attenuating effects of 5-ht3 receptor antagonist mdl 72222 on acute methamphetamine-induced locomotor hyperactivity in mice Synapse  2008 62:8-13  DOI:10.1002/syn.20461  PMID:17948891
    • Shin, E. J., Jeong, J. H., Kim, H. J., Jang, C. G., Yamada, K., Nabeshima, T., Kim, Y. C. Exposure to extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine d-1-like receptors in mice Journal of Pharmacological Sciences  2007 105:367-371  DOI:10.1254/jphs.SC0070348  PMID:18094524
    • Bae, J. W., Kim, M. J., Jang, C. G., Lee, S. Y. Determination of meloxicam in human plasma using a hplc method with uv detection and its application to a pharmacokinetic study Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences  2007 859:69-73  DOI:10.1016/j.jchromb.2007.09.004  PMID:17921074
    • Yoon, B. H., Jung, J. W., Lee, J. J., Cho, Y. W., Jang, C. G., Jin, C., Oh, T. H., Ryu, J. H. Anxiolytic-like effects of sinapic acid in mice Life Sciences  2007 81:234-240  DOI:10.1016/j.lfs.2007.05.007  PMID:17570441
    • Kim, J. H., Kim, S. Y., Lee, S. Y., Jang, C. G. Antidepressant-like effects of albizzia julibrissin in mice: Involvement of the 5-ht1a receptor system Pharmacology, Biochemistry and Behavior  2007 87:41-47  DOI:10.1016/j.pbb.2007.03.018  PMID:17477962
    • Yu, H. S., Lee, S. Y., Jang, C. G. Involvement of 5-ht1a and gaba(a) receptors in the anxiolytic-like effects of cinnamomum cassia in mice Pharmacology, Biochemistry and Behavior  2007 87:164-170  DOI:10.1016/j.pbb.2007.04.013  PMID:17512974
    • Lee, B. H., Lee, J. H., Lee, S. M., Jeong, S. M., Yoon, I. S., Choi, S. H., Pyo, M. K., Rhim, H., Jang, C. G., Kim, H. C., Park, C. S., Lee, B. C., et al. Identification of ginsenoside interaction sites in 5-ht3a receptors Neuropharmacology  2007 52:1139-1150  DOI:10.1016/j.neuropharm.2006.12.001  PMID:17257631
    • Bae, J. W., Kim, M. J., Park, Y. S., Myung, C. S., Jang, C. G., Lee, S. Y. Considerable interindividual variation in the pharmacokinetics of tolperisone hcl International Journal of Clinical Pharmacology and Therapeutics  2007 45:110-113  PMID:17323790
    • Yoo, J. H., Yang, E. M., Cho, J. H., Lee, J. H., Jeong, S. M., Nah, S. Y., Kim, H. C., Kim, K. W., Kim, S. H., Lee, S. Y., Jang, C. G. Inhibitory effects of berberine against morphine-induced locomotor sensitization and analgesic tolerance in mice Neuroscience  2006 142:953-961  DOI:10.1016/j.neuroscience.2006.07.008  PMID:16934942
    • Yoo, J. H., Cho, J. H., Yu, H. S., Lee, K. W., Lee, B. H., Jeong, S. M., Nah, S. Y., Kim, H. C., Lee, S. Y., Jang, C. G. Involvement of 5-ht3 receptors in the development and expression of methamphetamine-induced behavioral sensitization: 5-ht3a receptor channel and binding study Journal of Neurochemistry  2006 99:976-988  DOI:10.1111/j.1471-4159.2006.04137.x  PMID:16942594
    • Park, M. J., Lee, S. K., Lim, M. A., Chung, H. S., Cho, S. I., Jang, C. G., Lee, S. M. Effect of alpha-tocopherol and deferoxamine on methamphetamine-induced neurotoxicity Brain Research  2006 1109:176-182  DOI:10.1016/j.brainres.2006.06.030  PMID:16844102
    • Bae, J. W., Park, Y. S., Sohn, U. D., Myung, C. S., Ryu, B. K., Jang, C. G., Lee, S. Y. Hplc determination of tolperisone in human plasma Archives of Pharmacal Research  2006 29:339-342  DOI:10.1007/bf02968581  PMID:16681042
    • Yoo, J. H., Cho, J. H., Lee, S. Y., Lee, S., Loh, H. H., Ho, I. K., Jang, C. G. Differential effects of morphine- and cocaine-induced nnos immunoreactivity in the dentate gyrus of hippocampus of mice lacking mu-opioid receptors Neuroscience Letters  2006 395:98-102  DOI:10.1016/j.neulet.2005.10.089  PMID:16300892
    • Lee, S. Y., Jang, C. G. Increases in h-3 -alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor binding and mrna expression of ampa-sensitive glutamate receptor a (glur-a) subunits in rats withdrawn from butorphanol Journal of Toxicology and Environmental Health-Part A-Current Issues  2005 68:2163-2174  DOI:10.1080/15287390500177263  PMID:16326431
    • Bae, J. W., Kim, H. K., Kim, J. H., Yang, S. I., Kim, M. J., Jang, C. G., Park, Y. S., Lee, S. Y. Allele and genotype frequencies of cyp2c9 in a korean population British Journal of Clinical Pharmacology  2005 60:418-422  DOI:10.1111/j.1365-2125.2005.02448.x  PMID:16187974  PMCID:PMC1884827
    • Lee, J. H., Jeong, S. M., Kim, J. H., Lee, B. H., Yoon, I. S., Choi, S. H., Kim, D. H., Rhim, H., Jang, C. G., Kim, S. S., Kim, J. I., Nah, S. Y., et al. Characteristics of ginsenoside rg(3)-mediated brain na+ current inhibition Molecular Pharmacology  2005 68:1114-1126  DOI:10.1124/mol.105.015115  PMID:16014805
    • Kim, H. C., Shin, E. J., Jang, C. G., Lee, M. K., Eun, J. S., Hong, J. T., Oh, K. W. Pharmacological action of panax ginseng on the behavioral toxicities induced by psychotropic agents Archives of Pharmacal Research  2005 28:995-1001  DOI:10.1007/bf02977391  PMID:16212227
    • Jeong, S. M., Park, H. K., Yoon, I. S., Lee, J. H., Kim, J. H., Jang, C. G., Lee, C. J., Nah, S. Y. Cloning and expression of ca2+-activated chloride channel from rat brain Biochemical and Biophysical Research Communications  2005 334:569-576  DOI:10.1016/j.bbrc.2005.06.122  PMID:16023076
    • Yoo, J. H., Cho, J. H., Lee, S. Y., Loh, H. H., Ho, I. K., Jang, C. G. A lack of mu-opioid receptors modulates the expressions of neuropeptide y and substance p mrna Neuroscience Letters  2005 384:29-32  DOI:10.1016/j.neulet.2005.04.046  PMID:15885902
    • Yoo, J. H., Cho, J. H., Lee, S. Y., Loh, H. H., Ho, I. K., Jang, C. G. Reduced nnos expression induced by repeated nicotine treatment in mu-opioid receptor knockout mice Neuroscience Letters  2005 380:70-74  DOI:10.1016/j.neulet.2005.01.001  PMID:15854753
    • Jung, J. W., Cho, J. H., Ahn, N. Y., Oh, H. R., Kim, S. Y., Jang, C. G., Ryu, J. H. Effect of chronic albizzia julibrissin treatment on 5-hydroxytryptamine(1a) receptors in rat brain Pharmacology, Biochemistry and Behavior  2005 81:205-210  DOI:10.1016/j.pbb.2005.03.014  PMID:15894080
    • Kang, M., Pyun, K. H., Jang, C. G., Kim, H., Bae, H., Shim, I. Nelumbinis semen reverses a decrease in hippocampal 5-ht release induced by chronic mild stress in rats Journal of Pharmacy and Pharmacology  2005 57:651-656  DOI:10.1211/0022357056055  PMID:15901354
    • Yoo, J. H., Lee, S. Y., Loh, H. H., Ho, I. K., Jang, C. G. Altered emotional behaviors and the expression of 5-ht1a and m-1 muscarinic receptors in mu-opioid receptor knockout mice Synapse  2004 54:72-82  DOI:10.1002/syn.20067  PMID:15352132
    • Jang, C. G., Kang, M., Cho, J. H., Lee, S. B., Kim, H., Park, S., Lee, J., Park, S. K., Hong, M., Shin, M. K., Shim, I. S., Bae, H. Nelumbinis semen reverse's a decrease in 5-ht1a receptor binding induced by chronic mild stress, a depression-like symptom Archives of Pharmacal Research  2004 27:1065-1072  DOI:10.1007/bf02975433  PMID:15554266
    • Kwon, Y. S., Nabeshima, T., Shin, E. J., Chun, W., Jhoo, J. H., Jhoo, W. K., Wie, N. B., Jang, C. G., Chung, H., Sung, Y. E., Kim, H. C. Pap 9704, a korean herbal medicine attenuates methamphetamine-induced hyperlocomotion via adenosine a(2a) receptor stimulation in mice Biological & Pharmaceutical Bulletin  2004 27:906-909  DOI:10.1248/bpb.27.906  PMID:15187444
    • Yoo, J. H., Lee, S. Y., Loh, H. H., Ho, I. K., Jang, C. G. Loss of nicotine-induced behavioral sensitization in mu-opioid receptor knockout mice Synapse  2004 51:219-223  DOI:10.1002/syn.10303  PMID:14696009
    • Yang, S. I., Park, H. Y., Lee, S. H., Lee, S. J., Han, O. Y., Lim, S. C., Jang, C. G., Lee, W. S., Shin, Y. H., Kim, J. J., Lee, S. Y. Transdermal eperisone elicits more potent and longer-lasting muscle relaxation than oral eperisone Pharmacology  2004 71:150-156  DOI:10.1159/000077449  PMID:15161997
    • Jang, C. G., Lee, S. Y., Yoo, J. H., Yan, J. J., Song, D. K., Loh, H. H., Ho, I. K. Impaired water maze learning performance in mu-opioid receptor knockout mice Molecular Brain Research  2003 117:68-72  DOI:10.1016/s0169-328x(03)00291-2  PMID:14499482
    • Lee, S. Y., Song, D. K., Jang, C. G. Effects of coptis japonica on morphine-induced conditioned place preference in mice Archives of Pharmacal Research  2003 26:540-544  DOI:10.1007/bf02976878  PMID:12934646
    • Yoo, J. H., Yang, E. M., Lee, S. Y., Loh, H. H., Ho, I. K., Jang, C. G. Differential effects of morphine and cocaine on locomotor activity and sensitization in mu-opioid receptor knockout mice Neuroscience Letters  2003 344:37-40  DOI:10.1016/s0304-3940(03)00410-5  PMID:12781916
    • Park, Y., Jang, C. G., Yang, K. H., Loh, H. H., Ma, T. E., Ho, I. K. Regional specific increases of h-3 ampa binding and mrna expression of ampa receptors in the brain of mu-opioid receptor knockout mice Molecular Brain Research  2003 113:116-123  DOI:10.1016/s0169-328x(03)00123-2  PMID:12750013
    • Lee, S. H., Jang, C. G., Lee, S. Y. Tyrosine kinase is involved in hemin-induced pyresis Archives of Pharmacal Research  2003 26:411-415  DOI:10.1007/bf02976699  PMID:12785738
    • Jang, C. G., Lee, S. J., Yang, S. I., Kim, J. H., Sohn, U. D., Lee, S. Y. Carbon monoxide as a novel central pyrogenic mediator Archives of Pharmacal Research  2002 25:343-348  DOI:10.1007/bf02976637  PMID:12135108
    • Jang, C. G., Lee, S. Y., Lee, H. K., Suh, H. W., Song, D. K. Time courses of pcreb expression after dopaminergic stimulation by apomorphine in mouse brain Archives of Pharmacal Research  2002 25:370-374  DOI:10.1007/bf02976641  PMID:12135112
    • Lee, H. U., Lee, H. J., Park, H. Y., Lee, S. H., Jang, C. G., Lee, S. Y. Effects of heme oxygenase system on the cyclooxygenase in the primary cultured hypothalamic cells Archives of Pharmacal Research  2001 24:607-612  DOI:10.1007/bf02975174  PMID:11794544
    • Yun, J. S., Kim, H. S., Lee, M. K., Oh, K. W., Jang, C. G., Park, W. K., Seong, Y. H., Lee, S. C., Oh, S. K. Inhibitory effects of mk-801 on contextual sensitization to climbing behavior and on development of tolerance to hypothermia induced by a single high dose of apomorphine Pharmacological Research  2001 44:473-479  DOI:10.1006/phrs.2001.0889  PMID:11735353
    • Jang, C. G., Lee, S. Y. Nmda-type glutamatergic modulation in dopaminergic activation measured by apomorphine-induced cage climbing behaviors Archives of Pharmacal Research  2001 24:613-617  DOI:10.1007/bf02975175  PMID:11794545
    • Jang, C. G., Lee, S. Y., Park, Y., Ma, T. G., Loh, H. H., Ho, I. K. Differential effects of morphine, dpdpe, and u-50488 on apomorphine-induced climbing behavior in mu-opioid receptor knockout mice Molecular Brain Research  2001 94:197-199  DOI:10.1016/s0169-328x(01)00227-3  PMID:11597780
    • Jang, C. G., Lee, S. Y., Loh, H. H., Ho, I. K. Lack of mu-opioid receptor leads to an increase in the nmda receptor subunit mrna expression and nmda-induced convulsion Molecular Brain Research  2001 94:105-111  DOI:10.1016/s0169-328x(01)00222-4  PMID:11597770
    • Woo, S. H., Kim, H. S., Yun, J. S., Lee, M. K., Oh, K. W., Seong, Y. H., Oh, S. K., Jang, C. G. Inhibition of baclofen on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity Pharmacological Research  2001 43:335-340  DOI:10.1006/phrs.2000.0789  PMID:11352538
    • Park, Y., Ho, I. K., Jang, C. G., Tanaka, S., Ma, T., Loh, H. H., Ko, K. H. Effects of morphine on pentobarbital-induced responses in mu-opioid receptor knockout mice Brain Research Bulletin  2001 54:527-531  DOI:10.1016/s0361-9230(01)00444-0  PMID:11397543
    • Lim, H. K., Kim, H. S., Choi, H. S., Oh, S., Jang, C. G., Choi, J., Kim, S. H., Chang, M. J. Effects of acetylbergenin against d-galactosamine-induced hepatotoxicity in rats Pharmacological Research  2000 42:471-474  DOI:10.1006/phrs.2000.0730  PMID:11023710
    • Park, Y., Ma, T., Tanaka, S., Jang, C. G., Loh, H. H., Ko, K. H., Ho, I. K. Comparison of g-protein activation in the brain by mu-, delta-, and kappa-opioid receptor agonists in mu-opioid receptor knockout mice Brain Research Bulletin  2000 52:297-302  DOI:10.1016/s0361-9230(00)00265-3  PMID:10856828
    • Jang, C. G., Rockhold, R. W., Ho, I. K. An autoradiographic study of h-3 ampa receptor binding and in situ hybridization of ampa sensitive glutamate receptor a (glur-a) subunits following morphine withdrawal in the rat brain Brain Research Bulletin  2000 52:217-221  DOI:10.1016/s0361-9230(00)00261-6  PMID:10822164
    • Kim, H. S., Park, I. S., Lim, H. K., Choi, H. S., Oh, S., Park, W. K., Jang, C. G., Kim, S. H., Chang, M. J. N-methyl-d-aspartate receptor antagonists enhance the head-twitch response, a 5-hydroxytryptamine(2) receptor-mediated behaviour, in reserpine-treated mice Journal of Pharmacy and Pharmacology  2000 52:717-722  DOI:10.1211/0022357001774390  PMID:10875549
    • Jang, C. G., Park, Y., Tanaka, S., Ma, T. E., Loh, H. H., Ho, I. K. Involvement of mu-opioid receptors in potentiation of apomorphine-induced climbing behavior by morphine: Studies using mu-opioid receptor gene knockout mice Molecular Brain Research  2000 78:204-206  DOI:10.1016/s0169-328x(00)00094-2  PMID:10891603
    • Park, Y., Jang, C. G., Ho, I. K., Ko, K. H. Kappa-opioid agonist stimulated regional distribution of s-35 gtp gamma s binding in butorphanol continuously infused rat Brain Research Bulletin  2000 52:17-20  DOI:10.1016/s0361-9230(99)00274-9  PMID:10779697
    • Jang, C. G., Ho, I. K. N-methyl-d-aspartate receptor nr1 subunit mrna level was decreased in rat brain during pentobarbital withdrawal Neuroscience Letters  2000 282:129-132  DOI:10.1016/s0304-3940(00)00871-5  PMID:10717408
    • Oh, S., Jang, C. G., Ma, T., Ho, I. K. Activation of protein kinase c by phorbol dibutyrate modulates gaba(a) receptor binding in rat brain slices Brain Research  1999 850:158-165  DOI:10.1016/s0006-8993(99)02127-7  PMID:10629760
    • Jang, C. G., Park, Y., Rockhold, R. W., Ho, I. K. Autoradiographic study of nmda-displaceable h-3 glutamate and h-3 mk-801 binding during butorphanol withdrawal in the rat brain Brain Research  1999 845:236-241  DOI:10.1016/s0006-8993(99)01949-6  PMID:10536204
    • Zhu, H., Jang, C. G., Ma, T., Oh, S., Rockhold, R. W., Ho, I. K. Region specific expression of nmda receptor nr1 subunit mrna in hypothalamus and pons following chronic morphine treatment European Journal of Pharmacology  1999 365:47-54  DOI:10.1016/s0014-2999(98)00861-9  PMID:9988122
    • Jang, C. G., Oh, S., Zhu, H., Ho, I. K. Autoradiography of h-3 glutamate binding during pentobarbital tolerance and withdrawal in the rat Brain Research Bulletin  1999 48:99-102  DOI:10.1016/s0361-9230(98)00152-x  PMID:10210174
    • Jang, C. G., Rockhold, R. W., Ho, I. K. Withdrawal from butorphanol dependence alters binding of h-3 phorbol dibutyrate to protein kinase c, but not of h-3 forskolin to adenylate cyclase Brain Research  1999 821:520-525  DOI:10.1016/s0006-8993(99)01127-0  PMID:10064840
    • Jang, C. G., Oh, S. K., Ho, I. K. Changes in nmdar2 subunit mrna levels during pentobarbital tolerance/withdrawal in the rat brain: An in situ hybridization study Neurochemical Research  1998 23:1371-1377  DOI:10.1023/a:1020746505854  PMID:9814547
    • Oh, S. W., Jang, C. G., Ho, I. K. Activation of protein kinase c by phorbol dibutyrate potentiates h-3 mk-801 binding in rat brain slices Brain Research  1998 793:337-340  DOI:10.1016/s0006-8993(98)00272-8  PMID:9630713
    • Kim, H. S., Hong, Y. T., Jang, C. G. Effects of the ginsenosides rg(1) and rb-1 on morphine-induced hyperactivity and reinforcement in mice Journal of Pharmacy and Pharmacology  1998 50:555-560  PMID:9643450
    • Kim, H. S., Hong, Y. T., Oh, K. W., Seong, Y. H., Rheu, H. M., Cho, D. H., Oh, S., Park, W. K., Jang, C. G. Inhibition by ginsenosides rb-1 and rg(1) of methamphetamine-induced hyperactivity, conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice General Pharmacology  1998 30:783-789  DOI:10.1016/s0306-3623(97)00330-3  PMID:9559335
    • Kim, H. S., Jang, C. G., Oh, K. W., Oh, S., Rheu, H. M., Rhee, G. S., Seong, Y. H., Park, W. K. Effects of ginseng total saponin on morphine-induced hyperactivity and conditioned place preference in mice Journal of Ethnopharmacology  1998 60:33-42  DOI:10.1016/s0378-8741(97)00131-1  PMID:9533430
    • Kim, H. S., Park, W. K., Jang, C. G., Oh, K. W., Kong, J. Y., Oh, S., Rheu, H. M., Cho, D. H., Kang, S. Y. Blockade by naloxone of cocaine-induced hyperactivity, reverse tolerance and conditioned place preference in mice Behavioural Brain Research  1997 85:37-46  DOI:10.1016/s0166-4328(96)00162-3  PMID:9095340
    • Kim, H. S., Jang, C. G. Mk-801 inhibits methamphetamine-induced conditioned place preference and behavioral sensitization to apomorphine in mice Brain Research Bulletin  1997 44:221-227  DOI:10.1016/s0361-9230(97)00093-2  PMID:9323434
    • Kim, H. S., Jang, C. G., Park, W. K. Inhibition by mk-801 of morphine-induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice Pharmacology, Biochemistry and Behavior  1996 55:11-17  DOI:10.1016/0091-3057(96)00078-0  PMID:8870032
    • Kim, H. S., Rhee, G. S., Jung, J. Y., Lee, J. H., Jang, C. G., Park, W. K. Inhibition by noncompetitive nmda receptor antagonists of apomorphine-induced climbing behavior in mice Life Sciences  1996 58:1397-1402  DOI:10.1016/0024-3205(96)00109-9  PMID:8622565
    • Kim, H. S., Jang, C. G., Park, W. K., Oh, K. W., Rheu, H. M., Cho, D. H., Oh, S. K. Blockade by ginseng total saponin of methamphetamine-induced hyperactivity and conditioned place preference in mice General Pharmacology  1996 27:199-204  DOI:10.1016/0306-3623(95)02023-3  PMID:8919631
    • Kim, H. S., Jang, C. G., Oh, K. W., Seong, Y. H., Rheu, H. M., Cho, D. H., Kang, S. Y. Effects of ginseng total saponin on cocaine-induced hyperactivity and conditioned place preference in mice Pharmacology, Biochemistry and Behavior  1996 53:185-190  DOI:10.1016/0091-3057(95)00170-0  PMID:8848449
    • Kim, H. S., Park, W. K., Jang, C. G., Oh, S. Inhibition by mk-801 of cocaine-induced sensitization, conditioned place preference, and dopamine-receptor supersensitivity in mice Brain Research Bulletin  1996 40:201-207  DOI:10.1016/0361-9230(96)00006-8  PMID:8736582
    • Kim, H. S., Jang, C. G., Lee, M. K. Antinarcotic effects of the standardized ginseng extract g115 on morphine Planta Medica  1990 56:158-163  DOI:10.1055/s-2006-960915  PMID:2353061
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Background

education and training

  • Ph.D. in Pharmacology, Chungbuk National University , College of Pharmacy 1995
  • M.Sc. in Pharmacology, Chungbuk National University , College of Pharmacy 1989
  • B.Sc. in Pharmacy, Chungbuk National University , College of Pharmacy 1987
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Contact

full name

  • Choon-Gon Jang

geographic location

  • Scripps California 

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