recent publications
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academic article
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Jacob, N. T., Miranda, P. O., Shirey, R. J., Gautam, R., Zhou, B., Izquierdo, M. E. D., Hixon, M. S., Hart, J. R., Ueno, L., Vogt, P. K., Janda, K. D.
Synthetic molecules for disruption of the MYC protein-protein interface
Bioorganic & Medicinal Chemistry
2018
26:4234-4239
DOI:10.1016/j.bmc.2018.07.019
PMID:30037753
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Miranda, P. O., Cubitt, B., Jacob, N. T., Janda, K. D., de la Torre, J. C.
Mining a Kröhnke pyridine library for anti-arenavirus activity
ACS Infectious Diseases
2018
4:815-824
DOI:10.1021/acsinfecdis.7b00236
PMID:29405696
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Jacob, N. T., Anraku, K., Kimishima, A., Zhou, B., Collins, K. C., Lockner, J. W., Ellis, B. A., Janda, K. D.
A bioconjugate leveraging xenoreactive antibodies to alleviate cocaine-induced behavior
Chemical Communications
2017
53:8156-8159
DOI:10.1039/c7cc04055e
PMID:28677711
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Anraku, K., Sato, S., Jacob, N. T., Eubanks, L. M., Ellis, B. A., Janda, K. D.
The design and synthesis of an α-Gal trisaccharide epitope that provides a highly specific anti-Gal immune response
Organic & Biomolecular Chemistry
2017
15:2979-2992
DOI:10.1039/c7ob00448f
PMID:28294277
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Zhou, B., Eubanks, L. M., Jacob, N. T., Ellis, B., Roberts, A. J., Janda, K. D.
Studies towards the improvement of an anti-cocaine monoclonal antibody for treatment of acute overdose
Bioorganic & Medicinal Chemistry Letters
2016
26:5078-5081
DOI:10.1016/j.bmcl.2016.08.081
PMID:27599743
PMCID:PMC5050165
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Jacob, N. T., Lockner, J. W., Schlosburg, J. E., Ellis, B. A., Eubanks, L. M., Janda, K. D.
Investigations of enantiopure nicotine haptens using an adjuvanting carrier in anti-nicotine vaccine development
Journal of Medicinal Chemistry
2016
59:2523-2529
DOI:10.1021/acs.jmedchem.5b01676
PMID:26918428
- Frost, J. R., Jacob, N. T., Papa, L. J., Owens, A. E., Fasan, R. Ribosomal synthesis of macrocyclic peptides in vitro and in vivo mediated by genetically encoded aminothiol unnatural amino acids ACS Chemical Biology 2015 10:1805-1816 DOI:10.1021/acschembio.5b00119 PMID:25933125 PMCID:PMC4546577
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Jacob, N. T., Lockner, J. W., Kravchenko, V. V., Janda, K. D.
Pharmacophore reassignment for induction of the immunosurveillance cytokine TRAIL
Angewandte Chemie-International Edition
2014
53:6628-6631
DOI:10.1002/anie.201402133
PMID:24838721
- Frost, J. R., Vitali, F., Jacob, N. T., Brown, M. D., Fasan, R. Macrocyclization of organo-peptide hybrids through a dual bio-orthogonal ligation: insights from structure-reactivity studies ChemBioChem 2013 14:147-160 DOI:10.1002/cbic.201200579 PMID:23203912
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