recent publications
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academic article
- Epple, R., Cow, C., Xie, Y. P., Azimioara, M., Russo, R., Wang, X., Wityak, J., Karanewsky, D. S., Tuntland, T., Nguyen-Tran, V. T. B., Ngo, C. C., Huang, D., et al. Novel bisaryl substituted thiazoles and oxazoles as highly potent and selective peroxisome proliferator-activated receptor delta agonists Journal of Medicinal Chemistry 2010 53:77-105 DOI:10.1021/jm9007399 PMID:19928766
- Roppe, J. R., Wang, B. W., Huang, D. H., Tehrani, L., Kamenecka, T., Schweiger, E. J., Anderson, J. J., Brodkin, J., Jiang, X. H., Cramer, M., Chung, J., Reyes-Manalo, G., et al. 5-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity Bioorganic & Medicinal Chemistry Letters 2004 14:3993-3996 DOI:10.1016/j.bmcl.2004.05.037 PMID:15225713
- Wu, W. G., Pasternack, L., Huang, D. H., Koeller, K. M., Lin, C. C., Seitz, O., Wong, C. H. Structural study on O-glycopeptides: Glycosylation-induced conformational changes of O-GlcNAc, O-LacNAc, O-Sialyl-LacNAc, and O-Sialyl-Lewis-X peptides of the mucin domain of madcam-1 Journal of the American Chemical Society 1999 121:2409-2417 DOI:10.1021/ja983474v
- Kidd, R. D., Sears, P., Huang, D. H., Witte, K., Wong, C. H., Farber, G. K. Breaking the low barrier hydrogen bond in a serine protease Protein Science 1999 8:410-417 DOI:10.1110/ps.8.2.410 PMID:10048334 PMCID:PMC2144249
- Simanek, E. E., Huang, D. H., Pasternack, L., Machajewski, T. D., Seitz, O., Millar, D. S., Dyson, H. J., Wong, C. H. Glycosylation of threonine of the repeating unit of RNA polymerase II with beta-linked N-acetylglucosame leads to a turnlike structure Journal of the American Chemical Society 1998 120:11567-11575 DOI:10.1021/ja982312w
- Nicolaou, K. C., Yang, Z., Ouellette, M., Shi, G. Q., Gartner, P., Gunzner, J. L., Agrios, K. A., Huber, R., Chadha, R., Huang, D. H. New synthetic technology for the construction of 9-membered ring cyclic ethers. Construction of the EFGH ring skeleton of brevetoxin a Journal of the American Chemical Society 1997 119:8105-8106 DOI:10.1021/ja971219p
- Defrees, S. A., Kosch, W., Way, W., Paulson, J. C., Sabesan, S., Halcomb, R. L., Huang, D. H., Ichikawa, Y., Wong, C. H. Ligand recognition by e-selectin - synthesis, inhibitory activity, and conformational-analysis of bivalent sialyl-lewis-x analogs Journal of the American Chemical Society 1995 117:66-79 DOI:10.1021/ja00106a008
- Lin, Y. C., Hummel, C. W., Huang, D. H., Ichikawa, Y., Nicolaou, K. C., Wong, C. H. Conformational studies of sialyl lewis-x in aqueous-solution Journal of the American Chemical Society 1992 114:5452-5454 DOI:10.1021/ja00039a082
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