recent publications
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academic article
- Haniff, H. S., Liu, X. H., Tong, Y., Meyer, S. M., Knerr, L., Lemurell, M., Abegg, D., Aikawa, H., Adibekian, A., Disney, M. D. A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype Cell Chemical Biology 2022 29:300-311 DOI:10.1016/j.chembiol.2021.07.006 PMID:34320373 PMCID:PMC8867599
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Ye, F., Haniff, H. S., Suresh, B. M., Yang, D., Zhang, P., Crynen, G., Teijaro, C. N., Yan, W., Abegg, D., Adibekian, A., Shen, B., Disney, M. D.
Rational Approach to Identify RNA Targets of Natural Products Enables Identification of Nocathiacin as an Inhibitor of an Oncogenic RNA
ACS Chemical Biology
2022
17:474-482
DOI:10.1021/acschembio.1c00952
PMID:35044149
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Bush, J. A., Williams, C. C., Meyer, S. M., Tong, Y., Haniff, H. S., Childs-Disney, J. L., Disney, M. D.
Systematically Studying the Effect of Small Molecules Interacting with RNA in Cellular and Preclinical Models
ACS Chemical Biology
2021
16:1111-1127
DOI:10.1021/acschembio.1c00014
PMID:34166593
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Haniff, H. S., Tong, Y., Liu, X. H., Chen, J. L., Suresh, B. M., Andrews, R. J., Peterson, J. M., O'Leary, C. A., Benhamou, R. I., Moss, W. N., Disney, M. D.
Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders
ACS Central Science
2020
6:1713-1721
DOI:10.1021/acscentsci.0c00984
PMID:33140033
PMCID:PMC7553039
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Haniff, H. S., Knerr, L., Chen, J. L., Disney, M. D., Lightfoot, H. L.
Target-Directed Approaches for Screening Small Molecules against RNA Targets
SLAS Discovery
2020
DOI:10.1177/2472555220922802
PMID:32419578
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Haniff, H. S., Knerr, L., Liu, X. H., Crynen, G., Bostrom, J., Abegg, D., Adibekian, A., Lekah, E., Wang, K. W., Cameron, M. D., Yildirim, I., Lemurell, M., et al.
Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions
Nature Chemistry
2020
12:952-961
DOI:10.1038/s41557-020-0514-4
PMID:32839603
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Liu, X. H., Haniff, H. S., Childs-Disney, J. L., Shuster, A., Aikawa, H., Adibekian, A., Disney, M. D.
Targeted Degradation of the Oncogenic MicroRNA 17-92 Cluster by Structure-Targeting Ligands
Journal of the American Chemical Society
2020
142:6970-6982
DOI:10.1021/jacs.9b13159
PMID:32233464
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Costales, M. G., Childs-Disney, J. L., Haniff, H. S., Disney, M. D.
How We Think about Targeting RNA with Small Molecules
Journal of Medicinal Chemistry
2020
63:8880-8900
DOI:10.1021/acs.jmedchem.9b01927
PMID:32212706
PMCID:PMC7486258
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Childs-Disney, J. L., Tran, T., Vummidi, B. R., Velagapudi, S. P., Haniff, H. S., Matsumoto, Y., Crynen, G., Southern, M. R., Biswas, A., Wang, Z., Tellinghuisen, T. L., Disney, M. D.
A massively parallel selection of small molecule-RNA motif binding partners informs design of an antiviral from sequence
Chem
2018
4:2384-2404
DOI:10.1016/j.chempr.2018.08.003
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Velagapudi, S. P., Costales, M. G., Vummidi, B. R., Nakai, Y., Angelbello, A. J., Tran, T., Haniff, H. S., Matsumoto, Y., Wang, Z. F., Chatterjee, A. K., Childs-Disney, J. L., Disney, M. D.
Approved anti-cancer drugs target oncogenic non-coding RNAs
Cell Chemical Biology
2018
25:1086-1094
DOI:10.1016/j.chembiol.2018.05.015
PMID:30251629
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Haniff, H. S., Graves, A., Disney, M. D.
Selective small molecule recognition of RNA base pairs
ACS Combinatorial Science
2018
20:482-491
DOI:10.1021/acscombsci.8b00049
PMID:29966095
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Velagapudi, S. P., Luo, Y., Tran, T., Haniff, H. S., Nakai, Y., Fallahi, M., Martinez, G. J., Childs-Disney, J. L., Disney, M. D.
Defining RNA small molecule affinity landscapes enables design of a small molecule inhibitor of an oncogenic noncoding RNA
ACS Central Science
2017
3:205-216
DOI:10.1021/acscentsci.7b00009
PMID:28386598
PMCID:PMC5364451
- Belfield, K. D., Bondar, M. V., Haniff, H. S., Mikhailov, I. A., Luchita, G., Przhonska, O. V. Superfluorescent squaraine with efficient two-photon absorption and high photostability Chemphyschem 2013 14:3532-3542 DOI:10.1002/cphc.201300447 PMID:24022985