academic article

• Gruol, D. L. Neuroimmune actions in the brain and interactions with the effects of alcohol Neural Regeneration Research  2021 16:1791-1792  DOI:10.4103/1673-5374.306079  PMID:33510079
• Gruol, D. L., Melkonian, C., Ly, K., Sisouvanthong, J., Tan, Y., Roberts, A. J. Alcohol and IL-6 Alter Expression of Synaptic Proteins in Cerebellum of Transgenic Mice with Increased Astrocyte Expression of IL-6 Neuroscience  2020 442:124-137  DOI:10.1016/j.neuroscience.2020.06.043  PMID:32634532  PMCID:PMC7438304
• Gruol, D. L., Hernandez, R. V., Roberts, A. Alcohol Enhances Responses to High Frequency Stimulation in Hippocampus from Transgenic Mice with Increased Astrocyte Expression of IL-6 Cellular and Molecular Neurobiology  2020  DOI:10.1007/s10571-020-00902-6  PMID:32562098
• Gruol, D. L., Melkonian, C., Huitron-Resendiz, S., Roberts, A. J. Alcohol alters IL-6 Signal Transduction in the CNS of Transgenic Mice with Increased Astrocyte Expression of IL-6 Cellular and Molecular Neurobiology  2020  DOI:10.1007/s10571-020-00879-2  PMID:32447612
• Roberts, A. J., Khom, S., Bajo, M., Vlkolinsky, R., Polis, I., Cates-Gatto, C., Roberto, M., Gruol, D. L. Increased IL-6 expression in astrocytes is associated with emotionality, alterations in central amygdala GABAergic transmission, and excitability during alcohol withdrawal Brain Behavior and Immunity  2019 82:188-202  DOI:10.1016/j.bbi.2019.08.185  PMID:31437534  PMCID:PMC6800653
• Gruol, D. L., Huitron-Resendiz, S., Roberts, A. J. Altered brain activity during withdrawal from chronic alcohol is associated with changes in IL-6 signal transduction and GABAergic mechanisms in transgenic mice with increased astrocyte expression of IL-6 Neuropharmacology  2018 138:32-46  DOI:10.1016/j.neuropharm.2018.05.024  PMID:29787738
• Bray, J. G., Reyes, K. C., Roberts, A. J., Gruol, D. L. Altered hippocampal synaptic function in transgenic mice with increased astrocyte expression of CCL2 after withdrawal from chronic alcohol Neuropharmacology  2018 135:113-125  DOI:10.1016/j.neuropharm.2018.02.031  PMID:29499275  PMCID:PMC5975123
• Engberink, A. O., Hernandez, R., de Graan, P., Gruol, D. L. Rapamycin-sensitive late-LTP is enhanced in the hippocampus of IL-6 transgenic mice Neuroscience  2017 367:200-210  DOI:10.1016/j.neuroscience.2017.10.040  PMID:29104031  PMCID:PMC5728701
• Hernandez, R. V., Puro, A. C., Manos, J. C., Huitron-Resendiz, S., Reyes, K. C., Liu, K., Vo, K., Roberts, A. J., Gruol, D. L. Transgenic mice with increased astrocyte expression of IL-6 show altered effects of acute ethanol on synaptic function Neuropharmacology  2016 103:27-43  DOI:10.1016/j.neuropharm.2015.12.015  PMID:26707655  PMCID:PMC4755829
• Gruol, D. L. IL-6 regulation of synaptic function in the CNS Neuropharmacology  2015 96:42-54  DOI:10.1016/j.neuropharm.2014.10.023  PMID:25445486  PMCID:PMC4446251
• Gruol, D. L., Vo, K., Bray, J. G. Increased astrocyte expression of IL-6 or CCL2 in transgenic mice alters levels of hippocampal and cerebellar proteins Frontiers in Cellular Neuroscience  2014 8:234  DOI:10.3389/fncel.2014.00234  PMID:25177271  PMCID:PMC4132577
• Morhenn, V. B., Nelson, T. E., Gruol, D. L. The rate of wound healing is increased in psoriasis Journal of Dermatological Science  2013 72:87-92  DOI:10.1016/j.jdermsci.2013.06.001  PMID:23819987  PMCID:PMC4445836
• Gruol, D. L. Neuroimmune regulation of neurophysiology in the cerebellum Cerebellum  2013 12:307-309  DOI:10.1007/s12311-012-0445-8  PMID:23315008  PMCID:PMC3642226
• Bray, J. G., Reyes, K. C., Roberts, A. J., Ransohoff, R. M., Gruol, D. L. Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression Neuropharmacology  2013 67:115-125  DOI:10.1016/j.neuropharm.2012.11.007  PMID:23164616  PMCID:PMC3595200
• Gruol, D., Manto, M., Haines, D. Ca2+ signaling in cerebellar Purkinje neurons-editorial Cerebellum  2012 11:605-608  DOI:10.1007/s12311-012-0404-4  PMID:22806980  PMCID:PMC3570272
• Nelson, T. E., Engberink, A. O., Hernandez, R., Puro, A., Huitron-Resendiz, S., Hao, C., De Graan, P. N. E., Gruol, D. L. Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6 Brain Behavior and Immunity  2012 26:959-971  DOI:10.1016/j.bbi.2012.05.005  PMID:22609298  PMCID:PMC3427030
• Gruol, D. L., Nelson, T. E., Hao, C., Michael, S., Vukojevic, V., Ming, Y., Terenius, L. Ethanol alters opioid regulation of Ca2+influx through L-type Ca2+channels in PC12 cells Alcoholism-Clinical and Experimental Research  2012 36:443-456  DOI:10.1111/j.1530-0277.2011.01631.x  PMID:22014285  PMCID:PMC3266970
• Gruol, D. L., Puro, A., Hao, C., Blakely, P., Janneke, E., Vo, K. Neuroadaptive changes in cerebellar neurons induced by chronic exposure to IL-6 Journal of Neuroimmunology  2011 239:28-36  DOI:10.1016/j.jneuroim.2011.08.009  PMID:21890220  PMCID:PMC3428218
• Nelson, T. E., Hao, C., Manos, J., Ransohoff, R. M., Gruol, D. L. Altered hippocampal synaptic transmission in transgenic mice with astrocyte-targeted enhanced CCL2 expression Brain Behavior and Immunity  2011 25:S106-S119  DOI:10.1016/j.bbi.2011.02.013  PMID:21356306  PMCID:PMC4467826
• Kuijpers, M., van Gassen, K. L. I., de Graan, P. N. E., Gruol, D. Chronic exposure to the chemokine CCL3 enhances neuronal network activity in rat hippocampal cultures Journal of Neuroimmunology  2010 229:73-80  DOI:10.1016/j.jneuroim.2010.07.004  PMID:20678811  PMCID:PMC2991474
• Gruol, D. L., Netzeband, J. G., Nelson, T. E. Somatic CA(2+) signaling in cerebellar Purkinje neurons Journal of Neuroscience Research  2010 88:275-289  DOI:10.1002/jnr.22204  PMID:19681168
• Cho, J., Nelson, T. E., Bajova, H., Gruol, D. L. Chronic CXCL10 alters neuronal properties in rat hippocampal culture Journal of Neuroimmunology  2009 207:92-100  DOI:10.1016/j.jneuroim.2008.12.007  PMID:19167097  PMCID:PMC2817940
• Cho, J., Gruol, D. L. The chemokine CCL2 activates p38 mitogen-activated protein kinase pathway in cultured rat hippocampal cells Journal of Neuroimmunology  2008 199:94-103  DOI:10.1016/j.jneuroim.2008.05.011  PMID:18584881  PMCID:PMC2583399
• Bajova, H., Nelson, T. E., Gruol, D. L. Chronic CXCL10 alters the level of activated ERK1/2 and transcriptional factors CREB and NF-kappa B in hippocampal neuronal cell culture Journal of Neuroimmunology  2008 195:36-46  DOI:10.1016/j.jneuroim.2008.01.003  PMID:18329727  PMCID:PMC2396565
• Netzeband, J. G., Gruol, D. L. MGluR1 agonists elicit a Ca2+ signal and membrane hyperpolarization mediated by apamin-sensitive potassium channels in immature rat purkinje neurons Journal of Neuroscience Research  2008 86:293-305  DOI:10.1002/jnr.21493  PMID:17943990
• Sabeti, J., Gruol, D. L. Emergence of NMDAR-independent long-term potentiation at hippocampal CA1 synapses following early adolescent exposure to chronic intermittent ethanol: Role for sigma-receptors Hippocampus  2008 18:148-168  DOI:10.1002/hipo.20379  PMID:17960647
• Vereyken, E. J. F., Bajova, H., Chow, S., de Graan, P. N. E., Gruol, D. L. Chronic interleukin-6 alters the level of synaptic proteins in hippocampus in culture and in vivo European Journal of Neuroscience  2007 25:3605-3616  DOI:10.1111/j.1460-9568.2007.05615.x  PMID:17610580
• Sabeti, J., Nelson, T. E., Purdy, R. H., Gruol, D. L. Steroid pregnenolone sulfate enhances NMDA-receptor-independent long-term potentiation at hippocampal CA1 synapses: Role for L-type calcium channels and sigma-receptors Hippocampus  2007 17:349-369  DOI:10.1002/hipo.20273  PMID:17330865
• Gruol, D. L., Quina, L. A., Netzeband, J. G., Nguyen, D., Gullette, C. E. Developmental changes in Ca2+-regulated functions of early postnatal Purkinje neurons Journal of Neuroscience Research  2006 83:1381-1392  DOI:10.1002/jnr.20844  PMID:16555300
• Gruol, D. L., Netzeband, J. G., Schneeloch, J., Gullette, C. E. L-type Ca2+ channels contribute to current-evoked spike firing and associated Ca2+ signals in cerebellar Purkinje neurons Cerebellum  2006 5:146-154  DOI:10.1080/14734220600719692  PMID:16818389
• Gruol, D. L., Nelson, T. E. Purkinje neuron physiology is altered by the inflammatory factor interleukin-6 Cerebellum  2005 4:198-205  DOI:10.1080/14734220500199987  PMID:16147952
• Nelson, T. E., Ur, C. L., Gruol, D. L. Chronic intermittent ethanol exposure enhances NMDA-receptor-mediated synaptic responses and NMDA receptor expression in hippocampal Ca1 region Brain Research  2005 1048:69-79  DOI:10.1016/j.brainres.2005.04.041  PMID:15919065
• van Gassen, K. L. I., Netzeband, J. G., de Graan, P. N. E., Gruol, D. L. The chemokine CCL2 modulates Ca2+ dynamics and electrophysiological properties of cultured cerebellar Purkinje neurons European Journal of Neuroscience  2005 21:2949-2957  DOI:10.1111/j.1460-9568.2005.04113.x  PMID:15978006
• Rempel, J. D., Quina, L. A., Blakely-Gonzales, P. K., Buchmeier, M. J., Gruol, D. L. Viral induction of central nervous system innate immune responses Journal of Virology  2005 79:4369-4381  DOI:10.1128/jvi.79.7.4369-4381.2005  PMID:15767437
• Gruol, D. L., Netzeband, J. G., Quina, L. A., Blakely-Gonzalez, P. K. Contribution of L-type channels to Ca2+ regulation of neuronal properties in early developing purkinje neurons Cerebellum  2005 4:128-139  DOI:10.1080/14734220510007969  PMID:16035195
• Nelson, T. E., Netzeband, J. G., Gruol, D. L. Chronic interleukin-6 exposure alters metabotropic glutamate receptor-activated calcium signalling in cerebellar Purkinje neurons European Journal of Neuroscience  2004 20:2387-2400  DOI:10.1111/j.1460-9568.2004.03706.x  PMID:15525280
• Nelson, T. E., Gruol, D. L. The chemokine CXCL10 modulates excitatory activity and intracellular calcium signaling in cultured hippocampal neurons Journal of Neuroimmunology  2004 156:74-87  DOI:10.1016/j.jneuroim.2004.07.009  PMID:15465598
• Conroy, S. M., Nguyen, V., Quina, L. A., Blakely-Gonzales, P., Ur, C., Netzeband, J. G., Prieto, A. L., Gruol, D. L. Interleukin-6 produces neuronal loss in developing cerebellar granule neuron cultures Journal of Neuroimmunology  2004 155:43-54  DOI:10.1016/j.jneuroim.2004.06.014  PMID:15342195
• van Dalen, J. J. W., Gerendasy, D. D., de Graan, P. N. E., Schrama, L. H., Gruol, D. L. Calcium dynamics are altered in cortical neurons lacking the calmodulin-binding protein RC3 European Journal of Neuroscience  2003 18:13-22  DOI:10.1046/j.1460-9568.2003.02720.x  PMID:12859333
• Qiu, Z. H., Gruol, D. L. Interleukin-6, beta-amyloid peptide and NMDA interactions in rat cortical neurons Journal of Neuroimmunology  2003 139:51-57  DOI:10.1016/s0165-5728(03)00158-9  PMID:12799020
• Roberto, M., Nelson, T. E., Ur, C. L., Brunelli, M., Sanna, P. P., Gruol, D. L. The transient depression of hippocampal CA1 LTP induced by chronic intermittent ethanol exposure is associated with an inhibition of the MAP kinase pathway European Journal of Neuroscience  2003 17:1646-1654  DOI:10.1046/j.1460-9568.2003.02614.x  PMID:12752382
• Nelson, T. E., Ur, C. L., Gruol, D. L. Chronic interleukin-6 exposure alters electrophysiological properties and calcium signaling in developing cerebellar purkinje neurons in culture Journal of Neurophysiology  2002 88:475-486  DOI:10.1152/jn.00306.2001  PMID:12091569
• Roberto, M., Nelson, T. E., Ur, C. L., Gruol, D. L. Long-term potentiation in the rat hippocampus is reversibly depressed by chronic intermittent ethanol exposure Journal of Neurophysiology  2002 87:2385-2397  DOI:10.1152/jn.00145.2001  PMID:11976376
• Netzeband, J. G., Schneeloch, J. R., Trotter, C., Caguioa-Aquino, J. N., Gruol, D. L. Chronic ethanol treatment and withdrawal alter ACPD-evoked calcium signals in developing Purkinje neurons Alcoholism-Clinical and Experimental Research  2002 26:386-393  DOI:10.1111/j.1530-0277.2002.tb02550.x  PMID:11923593
• O'Barr, S. A., Caguioa, J., Gruol, D., Perkins, G., Ember, J. A., Hugli, T., Cooper, N. R. Neuronal expression of a functional receptor for the C5a complement activation fragment Journal of Immunology  2001 166:4154-4162  PMID:11238666
• Liljelund, P., Netzeband, J. G., Gruol, D. L. L-type calcium channels mediate calcium oscillations in early postnatal Purkinje neurons Journal of Neuroscience  2000 20:7394-7403  PMID:11007898
• Przewlocki, R., Parsons, K. L., Sweeney, D. D., Trotter, C., Netzeband, J. G., Siggins, G. R., Gruol, D. L. Opioid enhancement of calcium oscillations and burst events involving NMDA receptors and L-type calcium channels in cultured hippocampal neurons Journal of Neuroscience  1999 19:9705-9715  PMID:10559380
• Netzeband, J. G., Conroy, S. M., Parsons, K. L., Gruol, D. L. Cannabinoids enhance NMDA-elicited Ca2+ signals in cerebellar granule neurons in culture Journal of Neuroscience  1999 19:8765-8777  PMID:10516296
• Netzeband, J. G., Trotter, C., Caguioa, J. N., Gruol, D. L. Chronic ethanol exposure enhances AMPA-elicited Ca2+ signals in the somatic and dendritic regions of cerebellar Purkinje neurons Neurochemistry International  1999 35:163-174  DOI:10.1016/s0197-0186(99)00058-3  PMID:10406000
• Netzeband, J. G., Trotter, C., Parsons, K. L., Gruol, D. L. Chronic ethanol treatment alters AMPA-induced calcium signals in developing Purkinje neurons Brain Research  1999 826:270-280  DOI:10.1016/s0006-8993(99)01309-8  PMID:10224304
• Nelson, T. E., Campbell, I. L., Gruol, D. L. Altered physiology of Purkinje neurons in cerebellar slices from transgenic mice with chronic central nervous system expression of interleukin-6 Neuroscience  1999 89:127-136  DOI:10.1016/s0306-4522(98)00316-9  PMID:10051222
• Jacquin, T. D., Gruol, D. L. Ca2+ regulation of a large conductance K+ channel in cultured rat cerebellar Purkinje neurons European Journal of Neuroscience  1999 11:735-739  DOI:10.1046/j.1460-9568.1999.00478.x  PMID:10051775
• Nelson, T. E., Ur, C. L., Gruol, D. L. Chronic intermittent ethanol exposure alters CA1 synaptic transmission in rat hippocampal slices Neuroscience  1999 94:431-442  DOI:10.1016/s0306-4522(99)00336-x  PMID:10579206
• Meyer, J. H., Lee, S., Wittenberg, G. F., Randall, R. D., Gruol, D. L. Neurosteroid regulation of inhibitory synaptic transmission in the rat hippocampus in vitro Neuroscience  1999 90:1177-1183  DOI:10.1016/s0306-4522(98)00543-0  PMID:10338288
• Qiu, Z. H., Sweeney, D. D., Netzeband, J. G., Gruol, D. L. Chronic interleukin-6 alters NMDA receptor-mediated membrane responses and enhances neurotoxicity in developing CNS neurons Journal of Neuroscience  1998 18:10445-10456  PMID:9852582
• Gruol, D., Yu, N., Parsons, K. L., Billaud, J. N., Elder, J. H., Phillips, T. R. Neurotoxic effects of feline immunodeficiency virus, FIV-PPR Journal of Neurovirology  1998 4:415-425  PMID:9718133
• Gruol, D. L., Ryabinin, A. E., Parsons, K. L., Cole, M., Wilson, M. C., Qiu, Z. Neonatal alcohol exposure reduces NMDA induced Ca2+ signaling in developing cerebellar granule neurons Brain Research  1998 793:12-20  DOI:10.1016/s0006-8993(98)00014-6  PMID:9630481
• Gruol, D. L., Nelson, T. E. Physiological and pathological roles of interleukin-6 in the central nervous system Molecular Neurobiology  1997 15:307-339  DOI:10.1007/bf02740665  PMID:9457704
• Gruol, D. L., Parsons, K. L., DiJulio, N. Acute ethanol alters calcium signals elicited by glutamate receptor agonists and K+ depolarization in cultured cerebellar Purkinje neurons Brain Research  1997 773:82-89  DOI:10.1016/s0006-8993(97)00912-8  PMID:9409708
• Sorg, O., Horn, T. F. W., Yu, N. C., Gruol, D. L., Bloom, F. E. Inhibition of astrocyte glutamate uptake by reactive oxygen species: Role of antioxidant enzymes Molecular Medicine  1997 3:431-440  PMID:9260155  PMCID:PMC2230215
• Netzeband, J. G., Parsons, K. L., Sweeney, D. D., Gruol, D. L. Metabotropic glutamate receptor agonists alter neuronal excitability and Ca2+ levels via the phospholipase C transduction pathway in cultured Purkinje neurons Journal of Neurophysiology  1997 78:63-75  PMID:9242261
• Gruol, D. L., Netzeband, J. G., Parsons, K. L. Ca2+ signaling pathways linked to glutamate receptor activation in the somatic and dendritic regions of cultured cerebellar Purkinje neurons Journal of Neurophysiology  1996 76:3325-3340  PMID:8930276
• Gruol, D. L., Parsons, K. L. Chronic alcohol reduces calcium signaling elicited by glutamate receptor stimulation in developing cerebellar neurons Brain Research  1996 728:166-174  DOI:10.1016/s0006-8993(96)00185-0  PMID:8864478
• Gottlieb, R. A., Gruol, D. L., Zhu, J. Y., Engler, R. L. Preconditioning in rabbit cardiomyocytes - role of pH, vacuolar proton ATPase, and apoptosis Journal of Clinical Investigation  1996 97:2391-2398  DOI:10.1172/jci118683  PMID:8636421
• Randall, R. D., Lee, S. Y., Meyer, J. H., Wittenberg, G. F., Gruol, D. L. Acute alcohol blocks neurosteroid modulation of synaptic transmission and long-term potentiation in the rat hippocampal slice Brain Research  1995 701:238-248  DOI:10.1016/0006-8993(95)01007-9  PMID:8925287
• Qiu, Z. H., Parsons, K. L., Gruol, D. L. Interleukin-6 selectively enhances the intracellular calcium response to NMDA in developing CNS neurons Journal of Neuroscience  1995 15:6688-6699  PMID:7472429
• Netzeband, J. G., Gruol, D. L. Modulatory effects of acute ethanol on metabotropic glutamate responses in cultured Purkinje neurons Brain Research  1995 688:105-113  DOI:10.1016/0006-8993(95)00517-t  PMID:8542296
• Gruol, D. L., Curry, J. G. Calcium signals elicited by quisqualate in cultured Purkinje neurons show developmental-changes in sensitivity to acute alcohol Brain Research  1995 673:1-12  DOI:10.1016/0006-8993(94)01324-b  PMID:7757461
• Holliday, J., Parsons, K., Curry, J., Lee, S. Y., Gruol, D. L. Cerebellar granule neurons develop elevated calcium responses when treated with interleukin-6 in culture Brain Research  1995 673:141-148  DOI:10.1016/0006-8993(94)01417-g  PMID:7757467
• Gruol, D. L., Parsons, K. L. Chronic exposure to alcohol during development alters the calcium currents of cultured cerebellar Purkinje neurons Brain Research  1994 634:283-290  DOI:10.1016/0006-8993(94)91931-3  PMID:8131078
• Meyer, J. H., Gruol, D. L. Dehydroepiandrosterone-sulfate alters synaptic potentials in area CA1 of the hippocampal slice Brain Research  1994 633:253-261  PMID:8137159
• Fox, E. A., Gruol, D. L. Ionotropic and metabotropic components of electrophysiological response of cerebellar Purkinje neurons to excitatory amino-acids Brain Research  1993 631:59-64  DOI:10.1016/0006-8993(93)91186-v  PMID:7507790
• Holliday, J., Gruol, D. L. Cytokine stimulation increases intracellular calcium and alters the response to quisqualate in cultured cortical astrocytes Brain Research  1993 621:233-241  DOI:10.1016/0006-8993(93)90111-y  PMID:8242337
• Fox, E. A., Gruol, D. L. Corticotropin-releasing factor suppresses the afterhyperpolarization in cerebellar Purkinje neurons Neuroscience Letters  1993 149:103-107  DOI:10.1016/0304-3940(93)90358-r  PMID:8469370
• Gruol, D. L., Deal, C. R., Yool, A. J. Developmental-changes in calcium conductances contribute to the physiological maturation of cerebellar Purkinje neurons in culture Journal of Neuroscience  1992 12:2838-2848  PMID:1377238
• Gruol, D. L. Chronic exposure to alcohol during development alters the responses to excitatory amino-acids in cultured Purkinje neurons Brain Research  1992 574:271-279  PMID:1353402
• Yool, A. J., Krieger, R. M., Gruol, D. L. Multiple ionic mechanisms are activated by the potent agonist quisqualate in cultured cerebellar Purkinje neurons Brain Research  1992 573:83-94  DOI:10.1016/0006-8993(92)90116-q  PMID:1374285
• Urrutia, A., Gruol, D. L. Acute alcohol alters the excitability of cerebellar Purkinje neurons and hippocampal-neurons in culture Brain Research  1992 569:26-37  DOI:10.1016/0006-8993(92)90365-g  PMID:1611478
• Gruol, D. L. Chronic exposure to alcohol during development alters the membrane-properties of cerebellar Purkinje neurons in culture Brain Research  1991 558:1-12  DOI:10.1016/0006-8993(91)90707-3  PMID:1933370
• Gruol, D. L., Jacquin, T., Yool, A. J. Single-channel K+ currents recorded from the somatic and dendritic regions of cerebellar Purkinje neurons in culture Journal of Neuroscience  1991 11:1002-1015  PMID:2010802
• Franklin, C. L., Gruol, D. L. Developmental expression of excitatory amino-acid responses in cerebellar Purkinje neurons in culture Brain Research  1991 543:219-226  DOI:10.1016/0006-8993(91)90031-p  PMID:1676329
• Raska, I., Ochs, R. L., Andrade, L. E. C., Chan, E. K. L., Burlingame, R., Peebles, C., Gruol, D., Tan, E. M. Association between the nucleolus and the coiled body Journal of Structural Biology  1990 104:120-127  PMID:2088441
• Joels, M., Yool, A. J., Gruol, D. L. Unique properties of non-N-methyl-D-aspartate excitatory responses in cultured Purkinje neurons Proceedings of the National Academy of Sciences of the United States of America  1989 86:3404-3408  DOI:10.1073/pnas.86.9.3404  PMID:2470102
• Gruol, D. L., Dionne, V. E., Yool, A. J. Multiple voltage-sensitive K+ channels regulate dendritic excitability in cerebellar Purkinje neurons Neuroscience Letters  1989 97:97-102  DOI:10.1016/0304-3940(89)90146-8  PMID:2563909
• Yool, A. J., Dionne, V. E., Gruol, D. L. Developmental-changes in K+-selective channel activity during differentiation of the Purkinje neuron in culture Journal of Neuroscience  1988 8:1971-1980  PMID:2455025
• Gruol, D. L., Crimi, C. P. Morphological and physiological properties of rat cerebellar neurons in mature and developing cultures Developmental Brain Research  1988 41:135-146  DOI:10.1016/0165-3806(88)90177-0  PMID:2900061
• Yool, A. J., Gruol, D. L. Development of spontaneous and glutamate-evoked activity is altered by chronic ethanol in cultured cerebellar Purkinje neurons Brain Research  1987 420:205-219  DOI:10.1016/0006-8993(87)91240-6  PMID:2890413
• Franklin, C. L., Gruol, D. L. Acute ethanol alters the firing pattern and glutamate response of cerebellar Purkinje neurons in culture Brain Research  1987 416:205-218  DOI:10.1016/0006-8993(87)90899-7  PMID:2887251
• Gruol, D. L., Franklin, C. L. Morphological and physiological differentiation of Purkinje neurons in cultures of rat cerebellum Journal of Neuroscience  1987 7:1271-1293  PMID:2437259
• Siggins, G. R., Gruol, D., Aldenhoff, J., Pittman, Q. Electrophysiological actions of corticotropin-releasing factor in the central nervous-system Federation Proceedings  1985 44:237-242  PMID:3155696
• Gruol, D. L. Single channel analysis of voltage-sensitive k channels in cultured Purkinje neurons Biophysical Journal  1984 45:53-55  DOI:10.1016/S0006-3495(84)84105-3  PMID:19431562  PMCID:PMC1435264
• Aldenhoff, J. B., Gruol, D. L., Rivier, J., Vale, W., Siggins, G. R. Corticotropin releasing-factor decreases postburst hyperpolarizations and excites hippocampal-neurons Science  1983 221:875-877  DOI:10.1126/science.6603658  PMID:6603658
• Gruol, D. L. Cultured cerebellar neurons - endogenous and exogenous components of Purkinje-cell activity and membrane response to putative transmitters Brain Research  1983 263:223-241  DOI:10.1016/0006-8993(83)90315-3  PMID:6132671
• Gruol, D. L., Chavkin, C., Valentino, R. J., Siggins, G. R. Dynorphin-a alters the excitability of pyramidal neurons of the rat hippocampus in vitro Life Sciences  1983 33:533-536  DOI:10.1016/0024-3205(83)90558-1
• Gruol, D. L. Ethanol alters synaptic activity in cultured spinal-cord neurons Brain Research  1982 243:25-33  DOI:10.1016/0006-8993(82)91117-9  PMID:6126256
• Siggins, G. R., McGinty, J. F., Morrison, J. H., Pittman, Q. J., Zieglgansberger, W., Magistretti, P. J., Gruol, D. L. The role of neuropeptides in the hippocampal formation Advances in Biochemical Psychopharmacology  1982 33:413-422  PMID:6127004
• Gruol, D. L., Siggins, G. R., Padjen, A. L., Forman, D. S. Explant cultures of adult amphibian sympathetic-ganglia - electro-physiological and pharmacological investigation of neurotransmitter and nucleotide action Brain Research  1981 223:81-106  DOI:10.1016/0006-8993(81)90808-8  PMID:6116525
• Gruol, D. L., Smith, T. G. Opiate antagonism of glycine-evoked membrane polarizations in cultured mouse spinal-cord neurons Brain Research  1981 223:355-365  DOI:10.1016/0006-8993(81)91148-3  PMID:7284815
• Gruol, D. L., Barker, J. L., Huang, L. Y. M., Macdonald, J. F., Smith, T. G. Hydrogen-ions have multiple effects on the excitability of cultured mammalian neurons Brain Research  1980 183:247-252  DOI:10.1016/0006-8993(80)90138-9  PMID:7357408
• Gruol, D. L., Barker, J. L., Smith, T. G. Naloxone antagonism of GABA-evoked membrane polarizations in cultured mouse spinal-cord neurons Brain Research  1980 198:323-332  PMID:6250670
• Barker, J. L., Gruol, D. L., Huang, L. M., MacDonald, J. F., Smith, T. G., Jr. Peptide receptor functions on cultured spinal neurons Advances in Biochemical Psychopharmacology  1980 22:409-423  PMID:6104901
• Barker, J. L., Gruol, D. L., Huang, L. Y. M., Macdonald, J. F., Smith, T. G. Peptides - pharmacological evidence for 3 forms of chemical excitability in cultured mouse spinal neurons Neuropeptides  1980 1:63-82  DOI:10.1016/0143-4179(80)90010-4
• Gruol, D. L., Weinreich, D. Cooperative interactions of histamine and competitive antagonism by cimetidine at neuronal histamine-receptors in the marine mollusk, Aplysia-californica Neuropharmacology  1979 18:415-421  DOI:10.1016/0028-3908(79)90151-5  PMID:450207
• Gruol, D. L., Weinreich, D. Two pharmacologically distinct histamine receptors mediating membrane hyperpolarization on identified neurons of Aplysia californica Brain Research  1979 162:281-301  DOI:10.1016/0006-8993(79)90290-7  PMID:216467
• Siggins, G. R., Gruol, D. L., Padjen, A. L., Forman, D. S. Purine and pyrimidine mononucleotides depolarize neurons of explanted amphibian sympathetic-ganglia Nature  1977 270:263-265  DOI:10.1038/270263a0  PMID:201858
• Gruol, D., Rawson, J. R. Y., Haselkorn, R. Ribosomal-RNA genes in nucleus and chloroplast of Euglena Biochimica et Biophysica Acta  1975 414:20-29  DOI:10.1016/0005-2787(75)90122-7  PMID:811265