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Grover, Rajesh
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Grover, Rajesh

Faculty Member
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Positions

  • 2014 - Visiting Investigator, J. Craig Venter Institute
  • 2017 - 2018 Assistant Professor of Chemistry, Chemistry , Scripps Research
  • 2014 - 2017 Assistant Professor of CMB, Cell and Molecular Biology (CMB) , Scripps Research
  • 2010 - 2014 Senior Staff Scientist, Cell and Molecular Biology (CMB) , Scripps Research
  • 2007 - 2010 Staff Scientist, Cell and Molecular Biology (CMB) , Scripps Research
  • 2004 - 2007 Postdoctoral Fellow, Chemistry , Scripps Research
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Publications

recent publications

  • academic article

    • Lerner, R. A., Grover, R. K., Zhang, H., Xie, J., Han, K. H., Peng, Y., Yea, K. Antibodies from combinatorial libraries use functional receptor pleiotropism to regulate cell fates Quarterly Reviews of Biophysics  2015 48:389-394  DOI:10.1017/s0033583515000049  PMID:26537396
    • Grover, R. K., Zhu, X., Nieusma, T., Jones, T., Boero, I., MacLeod, A. S., Mark, A., Niessen, S., Kim, H. J., Kong, L., Assad-Garcia, N., Kwon, K., et al. A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union Science  2014 343:656-661  DOI:10.1126/science.1246135  PMID:24503852  PMCID:PMC3987992
    • Grover, R., Cheng, J. L., Peng, Y. J., Jones, T. M., Ruiz, D. I., Ulevitch, R. J., Glass, J. I., Dennis, E. A., Salomon, D. R., Lerner, R. A. The costimulatory immunogen LPS induces the B-cell clones that infiltrate transplanted human kidneys Proceedings of the National Academy of Sciences of the United States of America  2012 109:6036-6041  DOI:10.1073/pnas.1202214109  PMID:22492977  PMCID:PMC3341022
    • Nieva, J., Song, B. D., Rogel, J. K., Kujawara, D., Altobel, L., Izharrudin, A., Boldt, G. E., Grover, R., Wentworth, A. D., Wentworth, P. Cholesterol secosterol aldehydes induce amyloidogenesis and dysfunction of wild-type tumor protein p53 Chemistry & Biology  2011 18:920-927  DOI:10.1016/j.chembiol.2011.02.018  PMID:21802012  PMCID:PMC3148486
    • Heidebrecht, T., Christodoulou, E., Chalmers, M. J., Jan, S., Ter Riet, B., Grover, R., Joosten, R. P., Littler, D., van Luenen, H., Griffin, P. R., Wentworth, P., Borst, P., et al. The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1 Nucleic Acids Research  2011 39:5715-5728  DOI:10.1093/nar/gkr125  PMID:21415010  PMCID:PMC3141245
    • Cheng, J. L., Torkamani, A., Grover, R., Jones, T. M., Ruiz, D. I., Schork, N. J., Quigley, M. M., Hall, F. W., Salomon, D. R., Lerner, R. A. Ectopic B-cell clusters that infiltrate transplanted human kidneys are clonal Proceedings of the National Academy of Sciences of the United States of America  2011 108:5560-5565  DOI:10.1073/pnas.1101148108  PMID:21415369  PMCID:PMC3078383
    • Rao, P. N. P., Grover, R. K. Apricoxib, a COX-2 inhibitor for the potential treatment of pain and cancer IDrugs  2009 12:711-722  PMID:19844858
    • Grover, R., Pond, S. J. K., Cui, Q. Z., Subramaniam, P., Case, D. A., Millar, D. P., Wentworth, P. O-glycoside orientation is an essential aspect of base J recognition by the kinetoplastid DNA-binding protein JBP1 Angewandte Chemie-International Edition  2007 46:2839-2843  DOI:10.1002/anie.200604635  PMID:17295375
    • Grover, R. K., Roy, A. D., Roy, R., Joshi, S. K., Srivastava, V., Arora, S. K. Complete (1)H and (13)C NMR assignments of six saponins from Sapindus trifoliatus Magnetic Resonance in Chemistry  2005 43:1072-1076  DOI:10.1002/mrc.1675  PMID:16142834
    • Khurana, R., Coleman, C., Ionescu-Zanetti, C., Carter, S. A., Krishna, V., Grover, R. K., Roy, R., Singh, S. Mechanism of thioflavin T binding to amyloid fibrils Journal of Structural Biology  2005 151:229-238  DOI:10.1016/j.jsb.2005.06.006  PMID:16125973
    • Grover, R. K., Kesarwani, A. P., Srivastava, G. K., Kundu, B., Roy, R. Base catalyzed intramolecular transamidation of 2-aminoquinazoline derivatives on solid phase Tetrahedron  2005 61:5011-5018  DOI:10.1016/j.tet.2005.03.047
    • Kesarwani, A. P., Grover, R. K., Roy, R., Kundu, B. Solid-phase synthesis of imidazoquinazolinone derivatives with three-point diversity Tetrahedron  2005 61:629-635  DOI:10.1016/j.tet.2004.10.090
    • Roy, A. D., Sharma, S., Grover, R. K., Kundu, B., Roy, R. Novel intramolecular rearrangement leading to the synthesis of biheterocyclic indole-benzoimidazole derivatives on solid phase Organic Letters  2004 6:4763-4766  DOI:10.1021/ol0479794  PMID:15575680
    • Grover, R. K., Mishra, R. C., Kundu, B., Tripathi, R. P., Roy, R. In situ cyclopropanation: a rapid one-pot method for the synthesis of resin bound cyclopropyl phenyl methanones as combinatorial scaffolds Tetrahedron Letters  2004 45:7331-7334  DOI:10.1016/j.tetlet.2004.08.005
    • Grover, R. K., Maurya, R., Roy, R. Dynamic NMR investigation of two new interconvertible diasteriomeric epimers of natural 2-benzyl-2-hydroxybenzofuranone derivative from Pterocarpus marsupium Tetrahedron  2004 60:2005-2010  DOI:10.1016/j.tet.2004.01.012
    • Srivastava, G. K., Kesarwani, A. P., Grover, R. K., Roy, R., Srinivasan, T., Kundu, B. Solid phase synthesis of 2-aminoquinazoline-based compounds Journal of Combinatorial Chemistry  2003 5:769-774  DOI:10.1021/cc030043m  PMID:14606804
    • Rastogi, S. K., Srivastava, G. K., Singh, S. K., Grover, R. K., Roy, R., Kundu, B. Solid phase synthesis of 3,5-disubstituted oxazolidin-2-ones Tetrahedron Letters  2002 43:8327-8330  DOI:10.1016/s0040-4039(02)02009-9
    • Grover, R. K., Srivastva, S., Kulshreshtha, D. K., Roy, R. A new stereoisomer of stemmadenine alkaloid from Tabernaemontana heyneana Magnetic Resonance in Chemistry  2002 40:474-476  DOI:10.1002/mrc.1039
    • Biabani, M. A. F., Grover, R. K., Singh, S. K., Kumar, S., Raj, K., Roy, R., Kundu, B. A novel diterpenoid lactone-based scaffold for the generation of combinatorial libraries Tetrahedron Letters  2001 42:7119-7121  DOI:10.1016/s0040-4039(01)01479-4
    • Grover, R. K., Joshi, B. S., Batra, S., Roy, R., Bhaduri, A. P. Translactonization of erythromycin A during oximation: mixture analysis and reaction monitoring by NMR Magnetic Resonance in Chemistry  2001 39:355-360  DOI:10.1002/mrc.858
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Background

education and training

  • Ph.D. in Drug Discovery/ Biomedical Magnetic Resonance, CSIR - Central Drug Research Institute 1999 - 2004
  • M.Sc. in Chemistry/Biochemistry; minor: Biomedical Engineering, Indian Institute of Technology Delhi 1996 - 1998
  • B.Sc. in Chemistry and Physics (Honors), University of Delhi 1993 - 1996
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Contact

full name

  • Rajesh Grover

geographic location

  • Scripps California 

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