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Frosst, Phyllis
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Frosst, Phyllis

Graduate Student
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Positions

  • 2014 - Director, Policy and Government Affairs & Brand Director, Medical Countermeasures, Seqirus

Websites

  • Doctoral Dissertation
  • Publications
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Publications

recent publications
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  • Publications without PubMed PMIDs

  • academic article

    • Gitlin, J. M., Fischbeck, K., Crawford, T. O., Cwik, V., Fleischman, A., Gonye, K., Heine, D., Hobby, K., Kaufmann, P., Keiles, S., MacKenzie, A., Musci, T., et al. Carrier testing for spinal muscular atrophy Genetics in Medicine  2010 12:621-622  DOI:10.1097/GIM.0b013e3181ef6079  PMID:20808230
    • degree-related publication Ben-Efraim, I., Frosst, P. D., Gerace, L. Karyopherin binding interactions and nuclear import mechanism of nuclear pore complex protein tpr BMC Cell Biology  2009 10:74  DOI:10.1186/1471-2121-10-74  PMID:19835572  PMCID:PMC2770460
    • Frosst, P., Wattendorf, D. J. At-home genetic tests American Family Physician  2006 73:540-541  PMID:16477901
    • Hsu, C., Boysen, M., Gritton, L. D., Frosst, P. D., Nemerow, G. R., Von Seggern, D. J. In vitro dendritic cell infection by pseudotyped adenoviral vectors does not correlate with their in vivo immunogenicity Virology  2005 332:1-7  DOI:10.1016/j.virol.2004.11.014  PMID:15661134
    • Tran, P., Hiou-Tim, F., Frosst, P., Lussier-Cacan, S., Bagley, P., Selhub, J., Bottiglieri, T., Rozen, R. The curly-tail (ct) mouse, an animal model of neural tube defects, displays altered homocysteine metabolism without folate responsiveness or a defect in Mthfr Molecular Genetics and Metabolism  2002 76:297-304  DOI:10.1016/s1096-7192(02)00108-7  PMID:12208134
    • degree-related publication Frosst, P., Guan, T., Subauste, C., Hahn, K., Gerace, L. Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export Journal of Cell Biology  2002 156:617-630  DOI:10.1083/jcb.200106046  PMID:11839768  PMCID:PMC2174070
    • Goyette, P., Pai, A., Milos, R., Frosst, P., Tran, P., Chen, Z., Chan, M., Rozen, R. Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR) Mammalian Genome  1998 9:652-656  DOI:10.1007/s003359900838  PMID:9680386
    • Christensen, B., Frosst, P., Lussier-Cacan, S., Selhub, J., Goyette, P., Rosenblatt, D. S., Genest Jr., J., Rozen, R. Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease Arteriosclerosis Thrombosis and Vascular Biology  1997 17:569-573  PMID:9102178
    • Ma, J., Stampfer, M. J., Hennekens, C. H., Frosst, P., Selhub, J., Horsford, J., Malinow, M. R., Willett, W. C., Rozen, R. Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US Physicians Circulation  1996 94:2410-2416  PMID:8921781
    • Frosst, P., Zhang, Z., Pai, A., Rozen, R. The methylenetetrahydrofolate reductase (Mthfr) gene maps to distal mouse chromosome 4 Mammalian Genome  1996 7:864-865  DOI:10.1007/s003359900255  PMID:8875901
    • Kluijtmans, L. A. J., van den Heuvel, L. P. W. J., Boers, G. H. J., Frosst, P., Stevens, E. M. B., van Oost, B. A., den Heijer, M., Trijbels, F. J. M., Rozen, R., Blom, H. J. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease American Journal of Human Genetics  1996 58:35-41  PMID:8554066  PMCID:PMC1914961
    • Frosst, P., Blom, H. J., Milos, R., Goyette, P., Sheppard, C. A., Matthews, R. G., Boers, G. J. H., den Heijer, M., Kluijtmans, L. A. J., Van den Heuvel, L. P., Rozen, R. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase Nature Genetics  1995 10:111-113  DOI:10.1038/ng0595-111  PMID:7647779
    • van der Put, N. M. J., Steegers-Theunissen, R. P. M., Frosst, P., Trijbels, F. J. M., Eskes, T. K. A. B., van den Heuvel, L. P., Mariman, E. C. M., den Heyer, M., Rozen, R., Blom, H. J. Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida Lancet  1995 346:1070-1071  DOI:10.1016/s0140-6736(95)91743-8  PMID:7564788
    • Goyette, P., Frosst, P., Rosenblatt, D. S., Rozen, R. Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency American Journal of Human Genetics  1995 56:1052-1059  PMID:7726158  PMCID:PMC1801446
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Background

education and training

  • Ph.D. in Biology, Scripps Research 1995 - 2001
  • M.S. in Human Genetics, McGill University 1994 - 1995
  • B.S. in Molecular Biology and Human Genetics, McGill University 1991 - 1994

advisee of

  • graduate advising relationship

    • Gerace, Larry, Ph.D.  candidacy, 1996 - 2001
  • postdoc or fellow advising relationship

    • Nemerow, Glen, Ph.D.  candidacy, 2001 - 2003
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Contact

full name

  • Phyllis D Frosst

geographic location

  • Scripps California 

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