recent publications
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academic article
- Schwartz, R., Guichard, A., Franc, N. C., Roy, S., Bier, E. A drosophila model for clostridium difficile toxin CDT reveals interactions with multiple effector pathways iScience 2020 23 DOI:10.1016/j.isci.2020.100865 PMID:32058973 PMCID:PMC7011083
- Zheng, Q., Ma, A., Yuan, L., Gao, N., Feng, Q., Franc, N. C., Xiao, H. Apoptotic cell clearance in Drosophila melanogaster Frontiers in Immunology 2017 8 DOI:10.3389/fimmu.2017.01881
- Guillou, A., Troha, K., Wang, H., Franc, N. C., Buchon, N. The Drosophila CD36 homologue croquemort is required to maintain immune and gut homeostasis during development and aging PLoS Pathogens 2016 12 DOI:10.1371/journal.ppat.1005961 PMID:27780230 PMCID:PMC5079587
- Meehan, T. L., Joudi, T. F., Timmons, A. K., Taylor, J. D., Habib, C. S., Peterson, J. S., Emmanuel, S., Franc, N. C., McCall, K. Components of the engulfment machinery have distinct roles in corpse processing PLoS One 2016 11 DOI:10.1371/journal.pone.0158217 PMID:27347682 PMCID:PMC4922577
- Xiao, H., Wang, H., Silva, E. A., Thompson, J., Guillou, A., Yates III, J. R., Buchon, N., Franc, N. C. The Pallbearer E3 ligase promotes actin remodeling via RAC in efferocytosis by degrading the ribosomal protein S6 Developmental Cell 2015 32:19-30 DOI:10.1016/j.devcel.2014.11.015 PMID:25533207 PMCID:PMC4293263
- Han, C., Song, Y., Xiao, H., Wang, D., Franc, N. C., Jan, L. Y., Jan, Y. N. Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila Neuron 2014 81:544-560 DOI:10.1016/j.neuron.2013.11.021 PMID:24412417 PMCID:PMC3995171
- Van Goethem, E., Silva, E. A., Xiao, H., Franc, N. C. The Drosophila TRPP cation channel, PKD2 and Dmel/Ced-12 act in genetically distinct pathways during apoptotic cell clearance PLoS One 2012 7:e31488 DOI:10.1371/journal.pone.0031488 PMID:22347485 PMCID:PMC3275576
- Gronski, M. A., Kinchen, J. M., Juncadella, I. J., Franc, N. C., Ravichandran, K. S. An essential role for calcium flux in phagocytes for apoptotic cell engulfment and the anti-inflammatory response Cell Death and Differentiation 2009 16:1323-1331 DOI:10.1038/cdd.2009.55 PMID:19461656 PMCID:PMC2856475
- Cuttell, L., Vaughan, A., Silva, E., Escaron, C. J., Lavine, M., Van Goethem, E., Eid, J. P., Quirin, M., Franc, N. C. Undertaker, a Drosophila Junctophilin, links Draper-mediated phagocytosis and calcium homeostasis Cell 2008 135:524-534 DOI:10.1016/j.cell.2008.08.033 PMID:18984163
- Silva, E. A., Burden, J., Franc, N. C. In vivo and in vitro methods for studying apoptotic cell engulfment in Drosophila Methods in Enzymology 2008 446:39-59 DOI:10.1016/s0076-6879(08)01603-0 PMID:18603115
- Silva, E., Au-Yeung, H. W., Van Goethem, E., Burden, J., Franc, N. C. Requirement for a Drosophila E3-ubiquitin ligase in phagocytosis of apoptotic cells Immunity 2007 27:585-596 DOI:10.1016/j.immuni.2007.08.016 PMID:17936033
- Franc, N. C. Phagocytosis of apoptotic cells in mammals, Caenorhabditis elegans and Drosophila melanogaster: molecular mechanisms and physiological consequences Frontiers in Bioscience 2002 7:D1298-D1313 DOI:10.2741/franc PMID:11991836
- White, K., Lisi, S., Kurada, P., Franc, N., Bangs, P. Methods for studying apoptosis and phagocytosis of apoptotic cells in Drosophila tissues and cell lines Methods in Cell Biology 2001 66:321-338 DOI:10.1016/S0091-679X(01)66015-1 PMID:11396010
- Bangs, P., Franc, N., White, K. Molecular mechanisms of cell death and phagocytosis in Drosophila Cell Death and Differentiation 2000 7:1027-1034 DOI:10.1038/sj.cdd.4400754 PMID:11139274
- Franc, N. C., White, K. Innate recognition systems in insect immunity and development: new approaches in Drosophila Microbes and Infection 2000 2:243-250 DOI:10.1016/s1286-4579(00)00304-x PMID:10758400
- Franc, N. C., Heitzler, P., Ezekowitz, R. A. B., White, K. Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila Science 1999 284:1991-1994 DOI:10.1126/science.284.5422.1991 PMID:10373118
- Franc, N. C., White, K., Ezekowitz, R. A. B. Phagocytosis and development: back to the future Current Opinion in Immunology 1999 11:47-52 DOI:10.1016/s0952-7915(99)80009-0 PMID:10047544
- Franc, N. C., Dimarcq, J. L., Lagueux, M., Hoffmann, J., Ezekowitz, R. A. B. Croquemort, a novel Drosophila hemocyte/macrophage receptor that recognizes apoptotic cells Immunity 1996 4:431-443 DOI:10.1016/s1074-7613(00)80410-0 PMID:8630729
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