recent publications
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academic article
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Barton, L. M., Edwards, J. T., Johnson, E. C., Bukowski, E. J., Sausa, R. C., Byrd, E. F. C., Orlicki, J. A., Sabatini, J. J., Baran, P. S.
Impact of stereo- and regiochemistry on energetic materials
Journal of the American Chemical Society
2019
141:12531-12535
DOI:10.1021/jacs.9b06961
PMID:31361955
- Widen, J. C., Kempema, A. M., Baur, J. W., Skopec, H. M., Edwards, J. T., Brown, T. J., Brown, D. A., Meece, F. A., Harki, D. A. Helenalin analogues targeting NF-κB p65: thiol reactivity and cellular potency studies of varied electrophiles Chemmedchem 2018 13:303-311 DOI:10.1002/cmdc.201700752 PMID:29349898 PMCID:PMC5894512
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Merchant, R. R.*, Edwards, J. T.*, Qin, T., Kruszyk, M. M., Bi, C., Che, G., Bao, D. H., Qiao, W., Sun, L., Collins, M. R., Fadeyi, O. O., Gallego, G. M., et al.
Modular radical cross-coupling with sulfones enables access to sp(3)-rich (fluoro)alkylated scaffolds
Science
2018
360:75-80
DOI:10.1126/science.aar7335
PMID:29456201
(* = equal contribution)
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Edwards, J. T., Merchant, R. R., McClymont, K. S., Knouse, K. W., Qin, T., Malins, L. R., Vokits, B., Shaw, S. A., Bao, D. H., Wei, F. L., Zhou, T., Eastgate, M. D., et al.
Decarboxylative alkenylation
Nature
2017
545:213-218
DOI:10.1038/nature22307
PMID:28424520
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Smith, J. M., Qin, T., Merchant, R. R., Edwards, J. T., Malins, L. R., Liu, Z., Che, G., Shen, Z., Shaw, S. A., Eastgate, M. D., Baran, P. S.
Decarboxylative alkynylation
Angewandte Chemie-International Edition
2017
56:11906-11910
DOI:10.1002/anie.201705107
PMID:28636185
PMCID:PMC5792189
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Lo, J. C., Kim, D., Pan, C. M., Edwards, J. T., Yabe, Y., Gui, J. H., Qin, T., Gutierrez, S., Giacoboni, J., Smith, M. W., Holland, P. L., Baran, P. S.
Fe-catalyzed C-C bond construction from olefins via radicals
Journal of the American Chemical Society
2017
139:2484-2503
DOI:10.1021/jacs.6b13155
PMID:28094980
PMCID:PMC5314431
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Qin, T., Malins, L. R., Edwards, J. T., Merchant, R. R., Novak, A. J. E., Zhong, J. Z., Mills, R. B., Yan, M., Yuan, C., Eastgate, M. D., Baran, P. S.
Nickel-catalyzed barton decarboxylation and giese reactions: a practical take on classic transforms
Angewandte Chemie-International Edition
2017
56:260-265
DOI:10.1002/anie.201609662
PMID:27981703
PMCID:PMC5295468
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Qin, T., Cornella, J., Li, C., Malins, L. R., Edwards, J. T., Kawamura, S., Maxwell, B. D., Eastgate, M. D., Baran, P. S.
A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents
Science
2016
352:801-805
DOI:10.1126/science.aaf6123
PMID:27103669
PMCID:PMC4867118
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Wang, J., Qin, T., Chen, T. G., Wimmer, L., Edwards, J. T., Cornella, J., Vokits, B., Shaw, S. A., Baran, P. S.
Nickel-catalyzed cross-coupling of redox-active esters with boronic acids
Angewandte Chemie-International Edition
2016
55:9675-9678
DOI:10.1002/anie.201605463
PMID:27380912
PMCID:PMC5232357
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Cornella, J., Edwards, J. T., Qin, T., Kawamura, S., Wang, J., Pan, C. M., Gianatassio, R., Schmidt, M., Eastgate, M. D., Baran, P. S.
Practical Ni-catalyzed aryl-alkyl cross-coupling of secondary redox-active esters
Journal of the American Chemical Society
2016
138:2174-2177
DOI:10.1021/jacs.6b00250
PMID:26835704
PMCID:PMC4768290
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Yan, M., Lo, J. C., Edwards, J. T., Baran, P. S.
Radicals: reactive intermediates with translational potential
Journal of the American Chemical Society
2016
138:12692-12714
DOI:10.1021/jacs.6b08856
PMID:27631602
PMCID:PMC5054485
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