recent publications
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academic article
- Tsutakawa, S. E., Classen, S., Chapados, B. R., Arvai, A. S., Finger, L. D., Guenther, G., Tomlinson, C. G., Thompson, P., Sarker, A. H., Shen, B. H., Cooper, P. K., Grasby, J. A., et al. Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the fen1 superfamily Cell 2011 145:198-211 DOI:10.1016/j.cell.2011.03.004 PMID:21496641 PMCID:PMC3086263
- Zeitlin, S. G., Chapados, B. R., Baker, N. M., Tai, C., Slupphaug, G., Wang, J. Y. J. Uracil DNA N-glycosylase promotes assembly of human centromere protein A PLoS One 2011 6 DOI:10.1371/journal.pone.0017151 PMID:21399697 PMCID:PMC3047565
- Tomlinson, C. G., Atack, J. M., Chapados, B., Tainer, J. A., Grasby, J. A. Substrate recognition and catalysis by flap endonucleases and related enzymes Biochemical Society Transactions 2010 38:433-437 DOI:10.1042/BST0380433 PMID:20298197
- Zeitlin, S. G., Baker, N. M., Chapados, B. R., Soutoglou, E., Wang, J. Y. J., Berns, M. W., Cleveland, D. W. Double-strand DNA breaks recruit the centromeric histone CENP-A Proceedings of the National Academy of Sciences of the United States of America 2009 106:15762-15767 DOI:10.1073/pnas.0908233106 PMID:19717431 PMCID:PMC2747192
- Syson, K., Tomlinson, C., Chapados, B. R., Sayers, J. R., Tainer, J. A., Williams, N. H., Grasby, J. A. Three metal ions participate in the reaction catalyzed by t5 flap endonuclease Journal of Biological Chemistry 2008 283:28741-28746 DOI:10.1074/jbc.M801264200 PMID:18697748 PMCID:PMC2568906
- Williams, R., Sengerowa, B., Osborne, S., Syson, K., Ault, S., Kilgour, A., Chapados, B. R., Tainer, J. A., Sayers, J. R., Grasby, J. A. Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease Journal of Molecular Biology 2007 371:34-48 DOI:10.1016/j.jmb.2007.04.063 PMID:17559871 PMCID:PMC1993357
- Vijayakumar, S., Chapados, B. R., Schmidt, K. H., Kolodner, R. D., Tainer, J. A., Tomkinson, A. E. The c-terminal domain of yeast pcna is required for physical and functional interactions with cdc9 DNA ligase Nucleic Acids Research 2007 35:1624-1637 DOI:10.1093/nar/gkm006 PMID:17308348 PMCID:PMC1865074
- Ivanov, I., Chapados, B. R., McCammon, J. A., Tainer, J. A. Proliferating cell nuclear antigen loaded onto double-stranded DNA: Dynamics, minor groove interactions and functional implications Nucleic Acids Research 2006 34:6023-6033 DOI:10.1093/nar/gkl744 PMID:17071716 PMCID:PMC1635319
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Chao, J. A., Lee, J. H., Chapados, B. R., Debler, E. W., Schneemann, A., Williamson, J. R.
Dual modes of RNA-silencing suppression by Flock House virus protein B2
Nature Structural & Molecular Biology
2005
12:952-957
DOI:10.1038/nsmb1005
PMID:16228003
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Qiu, J. Z., Liu, R., Chapados, B. R., Sherman, M., Tainer, J. A., Shen, B. H.
Interaction interface of human flap endonuclease-1 with its DNA substrates
Journal of Biological Chemistry
2004
279:24394-24402
DOI:10.1074/jbc.M401464200
PMID:15037610
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Chapados, B. R., Hosfield, D. J., Han, S., Qiu, J. Z., Yelent, B., Shen, B. H., Tainer, J. A.
Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair
Cell
2004
116:39-50
DOI:10.1016/s0092-8674(03)01036-5
PMID:14718165
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Chai, Q., Qiu, J., Chapados, B. R., Shen, B.
Archaeoglobus fulgidus RNase HII in DNA replication: enzymological functions and activity regulation via metal cofactors
Biochemical and Biophysical Research Communications
2001
286:1073-1081
DOI:10.1006/bbrc.2001.5523
PMID:11527410
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Chapados, B. R., Chai, Q., Hosfield, D. J., Qiu, J. Z., Shen, B. H., Tainer, J. A.
Structural biochemistry of a type 2 rnase h: Rna primer recognition and removal during DNA replication
Journal of Molecular Biology
2001
307:541-556
DOI:10.1006/jmbi.2001.4494
PMID:11254381
- Kabza, K. G., Chapados, B. R., Gestwicki, J. E., McGrath, J. L. Microwave-induced esterification using heterogeneous acid catalyst in a low dielectric constant medium Journal of Organic Chemistry 2000 65:1210-1214 DOI:10.1021/jo990515c PMID:10814074