academic article

• Johnson, J. L., Ramadass, M., Rahman, F., Meneses-Salas, E., Zgajnar, N. R., Gontijo, R. C., Zhang, J. Z., Kiosses, W. B., Zhu, Yfpp, Hedrick, C. C., Perego, M., Gunton, J. E., et al. The atypical small GTPase GEM/Kir is a negative regulator of the NADPH oxidase and NETs production through macroautophagy Journal of Leukocyte Biology  2021 110:629-649  DOI:10.1002/jlb.2hi0421-123r  PMID:34085299
• Zeng, F. R., Chen, Z. Z., Chen, R., Shufesky, W. J., Bandyopadhyay, M., Camirand, G., Oberbarnscheidt, M. H., Sullivan, M. L. G., Baty, C. J., Yang, M. Q., Calderon, M., Stolz, D. B., et al. Graft-derived extracellular vesicles transported across subcapsular sinus macrophages elicit B cell alloimmunity after transplantation Science Translational Medicine  2021 13  DOI:10.1126/scitranslmed.abb0122  PMID:33731430
• Rahman, F., Johnson, J. L., Zhang, J. Z., He, J., Pestonjamasp, K., Cherqui, S., Catz, S. D. DYNC1LI2 regulates localization of the chaperone-mediated autophagy receptor LAMP2A and improves cellular homeostasis in cystinosis Autophagy  2021  DOI:10.1080/15548627.2021.1971937  PMID:34643468
• Karmakar, M., Minns, M., Greenberg, E. N., Diaz-Aponte, J., Pestonjamasp, K., Johnson, J. L., Rathkey, J. K., Abbott, D. W., Wang, K., Shao, F., Catz, S. D., Dubyak, G. R., et al. N-GSDMD trafficking to neutrophil organelles facilitates IL-1 beta release independently of plasma membrane pores and pyroptosis Nature Communications  2020 11  DOI:10.1038/s41467-020-16043-9  PMID:32371889  PMCID:PMC7200749
• Catz, S. D., McLeish, K. R. Therapeutic targeting of neutrophil exocytosis Journal of Leukocyte Biology  2020  DOI:10.1002/jlb.3ri0120-645r  PMID:31990103
• Rohwedder, I., Kurz, A. R. M., Pruenster, M., Immler, R., Pick, R., Eggersmann, T., Klapproth, S., Johnson, J. L., Alsina, S. M., Lowell, C. A., Mocsai, A., Catz, S. D., et al. Src family kinase-mediated vesicle trafficking is critical for neutrophil basement membrane penetration Haematologica  2019 105:1845-1856  DOI:10.3324/haematol.2019.225722  PMID:31699792  PMCID:PMC7327629
• Zhang, J., He, J., Johnson, J. L., Napolitano, G., Ramadass, M., Rahman, F., Catz, S. D. Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency Autophagy  2019 15:1738-1756  DOI:10.1080/15548627.2019.1596475  PMID:30892133
• Lobry, T., Miller, R., Nevo, N., Rocca, C. J., Zhang, J., Catz, S. D., Moore, F., Thomas, L., Pouly, D., Bailleux, A., Guerrera, I. C., Gubler, M. C., et al. Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis Kidney International  2019 96:350-362  DOI:10.1016/j.kint.2019.01.029  PMID:30928021
• Ramadass, M., Johnson, J. L., Marki, A., Zhang, J., Wolf, D., Kiosses, W. B., Pestonjamasp, K., Ley, K., Catz, S. D. The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration Journal of Leukocyte Biology  2019 105:1209-1224  DOI:10.1002/jlb.1vma0818-320r  PMID:30748033  PMCID:PMC6543538
• Zhang, J., He, J., Johnson, J. L., Rahman, F., Gavathiotis, E., Cuervo, A. M., Catz, S. D. Chaperone-mediated autophagy upregulation rescues megalin expression and localization in cystinotic proximal tubule cells Frontiers in Endocrinology  2019 10  DOI:10.3389/fendo.2019.00021
• Ley, K., Hoffman, H. M., Kubes, P., Cassatella, M. A., Zychlinsky, A., Hedrick, C. C., Catz, S. D. Neutrophils: New insights and open questions Science Immunology  2018 3  DOI:10.1126/sciimmunol.aat4579  PMID:30530726
• Kurz, A. R. M., Catz, S. D., Sperandio, M. Noncanonical hippo signalling in the regulation of leukocyte function Trends in Immunology  2018 39:656-669  DOI:10.1016/j.it.2018.05.003  PMID:29954663
• Johnson, J. L., Ramadass, M., Haimovich, A., McGeough, M. D., Zhang, J., Hoffman, H. M., Catz, S. D. Increased neutrophil secretion induced by NLRP3 mutation links the inflammasome to azurophilic granule exocytosis Frontiers in Cellular and Infection Microbiology  2017 7  DOI:10.3389/fcimb.2017.00507
• Catz, S. D. Editorial: The secrets of secretion Journal of Leukocyte Biology  2017 102:4-6  DOI:10.1189/jlb.3CE0217-046R  PMID:28667084
• Zhang, J., Johnson, J. L., He, J., Napolitano, G., Ramadass, M., Rocca, C., Kiosses, W. B., Bucci, C., Xin, Q., Gavathiotis, E., Cuervo, A. M., Cherqui, S., et al. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A Journal of Biological Chemistry  2017 292:10328-10346  DOI:10.1074/jbc.M116.764076  PMID:28465352  PMCID:PMC5481548
• Ramadass, M., Johnson, J. L., Catz, S. D. Rab27a regulates GM-CSF-dependent priming of neutrophil exocytosis Journal of Leukocyte Biology  2017 101:693-702  DOI:10.1189/jlb.3AB0416-189RR  PMID:27733578
• Johnson, J. L., Ramadass, M., He, J., Brown, S. J., Zhang, J., Abgaryan, L., Biris, N., Gavathiotis, E., Rosen, H., Catz, S. D. Identification of neutrophil exocytosis inhibitors (Nexinhibs), small molecule inhibitors of neutrophil exocytosis and inflammation: druggability of the small GTPase Rab27a Journal of Biological Chemistry  2016 291:25965-25982  DOI:10.1074/jbc.M116.741884  PMID:27702998  PMCID:PMC5207069
• Kurz, A. R. M., Pruenster, M., Rohwedder, I., Ramadass, M., Schafer, K., Harrison, U., Gouveia, G., Nussbaum, C., Immler, R., Wiessner, J. R., Margraf, A., Lim, D. S., et al. MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membrane Journal of Clinical Investigation  2016 126:4125-4139  DOI:10.1172/jci87043  PMID:27701149  PMCID:PMC5096904
• Ramadass, M., Catz, S. D. Molecular mechanisms regulating secretory organelles and endosomes in neutrophils and their implications for inflammation Immunological Reviews  2016 273:249-265  DOI:10.1111/imr.12452  PMID:27558339
• Rega, L. R., Polishchuk, E., Montefusco, S., Napolitano, G., Tozzi, G., Zhang, J., Bellomo, F., Taranta, A., Pastore, A., Polishchuk, R., Piemonte, F., Medina, D. L., et al. Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells Kidney International  2016 89:862-873  DOI:10.1016/j.kint.2015.12.045  PMID:26994576
• Johnson, J. L., He, J., Ramadass, M., Pestonjamasp, K., Kiosses, W. B., Zhang, J. Z., Catz, S. D. Munc13-4 Is a Rab11-binding protein that regulates Rab11-positive vesicle trafficking and docking at the plasma membrane Journal of Biological Chemistry  2016 291:3423-3438  DOI:10.1074/jbc.M115.705871  PMID:26637356  PMCID:PMC4751385
• He, J., Johnson, J. L., Monfregola, J., Ramadass, M., Pestonjamasp, K., Napolitano, G., Zhang, J., Catz, S. D. Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses Molecular Biology of the Cell  2016 27:572-587  DOI:10.1091/mbc.E15-05-0283  PMID:26680738  PMCID:PMC4751605
• Napolitano, G., Johnson, J. L., He, J., Rocca, C. J., Monfregola, J., Pestonjamasp, K., Cherqui, S., Catz, S. D. Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis EMBO Molecular Medicine  2015 7:158-174  DOI:10.15252/emmm.201404223  PMID:25586965  PMCID:PMC4328646
• Sasaki, T., Lian, S., Qi, J., Bayliss, P. E., Carr, C. E., Johnson, J. L., Guha, S., Kobler, P., Catz, S. D., Gill, M., Jia, K., Klionsky, D. J., et al. Aberrant autolysosomal regulation is linked to the induction of embryonic senescence: differential roles of Beclin 1 and p53 in vertebrate Spns1 deficiency PLoS Genetics  2014 10:e1004409  DOI:10.1371/journal.pgen.1004409  PMID:24967584  PMCID:PMC4072523
• Catz, S. D. Regulation of vesicular trafficking and leukocyte function by Rab27 GTPases and their effectors Journal of Leukocyte Biology  2013 94:613-622  DOI:10.1189/jlb.1112600  PMID:23378593  PMCID:PMC3774847
• Johnson, J. L., Napolitano, G., Monfregola, J., Rocca, C. J., Cherqui, S., Catz, S. D. Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis Molecular and Cellular Biology  2013 33:2950-2962  DOI:10.1128/mcb.00417-13  PMID:23716592  PMCID:PMC3719680
• Singh, R. K., Mizuno, K., Wasmeier, C., Wavre-Shapton, S. T., Recchi, C., Catz, S. D., Futter, C., Tolmachova, T., Hume, A. N., Seabra, M. C. Distinct and opposing roles for Rab27a/MIph/MyoVa and Rab27b/Munc13-4 in mast cell secretion FEBS Journal  2013 280:892-903  DOI:10.1111/febs.12081  PMID:23281710
• Johnson, J. L., Monfregola, J., Napolitano, G., Kiosses, W. B., Catz, S. D. Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein Molecular Biology of the Cell  2012 23:1902-1916  DOI:10.1091/mbc.E11-12-1001  PMID:22438581  PMCID:PMC3350554
• Johnson, J. L., Hong, H., Monfregola, J., Catz, S. D. Increased survival and reduced neutrophil infiltration of the liver in Rab27a-but not Munc13-4-deficient mice in lipopolysaccharide-induced systemic inflammation Infection and Immunity  2011 79:3607-3618  DOI:10.1128/iai.05043-11  PMID:21746860  PMCID:PMC3165471
• Johnson, J. L., Hong, H., Monfregola, J., Kiosses, W. B., Catz, S. D. Munc13-4 restricts motility of rab27a-expressing vesicles to facilitate lipopolysaccharide-induced priming of exocytosis in neutrophils Journal of Biological Chemistry  2011 286:5647-5656  DOI:10.1074/jbc.M110.184762  PMID:21148308  PMCID:PMC3037678
• Johnson, J. L., Brzezinska, A. A., Tolmachova, T., Munafo, D. B., Ellis, B. A., Seabra, M. C., Hong, H., Catz, S. D. Rab27a and Rab27b regulate neutrophil azurophilic granule exocytosis and NADPH oxidase activity by independent mechanisms Traffic  2010 11:533-547  DOI:10.1111/j.1600-0854.2009.01029.x  PMID:20028487  PMCID:PMC2937183
• Brzezinska, A. A., Johnson, J. L., Munafo, D. B., Ellis, B. A., Catz, S. D. Signalling mechanisms for toll-like receptor-activated neutrophil exocytosis: Key roles for interleukin-1-receptor-associated kinase-4 and phosphatidylinositol 3-kinase but not toll/il-1 receptor (tir) domain-containing adaptor inducing ifn-beta (trif) Immunology  2009 127:386-397  DOI:10.1111/j.1365-2567.2008.02980.x  PMID:19019092  PMCID:PMC2712107
• Munafo, D. B., Johnson, J. L., Brzezinska, A. A., Ellis, B. A., Wood, M. R., Catz, S. D. DNase I inhibits a late phase of reactive oxygen species production in neutrophils Journal of Innate Immunity  2009 1:527-542  DOI:10.1159/000235860  PMID:20375609  PMCID:PMC2919508
• Brzezinska, A. A., Johnson, J. L., Munafo, D. B., Crozat, K., Beutler, B., Kiosses, W. B., Ellis, B. A., Catz, S. D. The Rab27a effectors JFC1/Slp1 and Munc13-4 regulate exocytosis of neutrophil granules Traffic  2008 9:2151-2164  DOI:10.1111/j.1600-0854.2008.00838.x  PMID:18939952
• Pacquelet, S., Johnson, J. L., Ellis, B. A., Brzezinska, A. A., Lane, W. S., Munafo, D. B., Catz, S. D. Cross-talk between IRAK-4 and the NADPH oxidase Biochemical Journal  2007 403:451-461  DOI:10.1042/bj20061184  PMID:17217339
• Munafo, D. B., Johnson, J. L., Ellis, B. A., Rutschmann, S., Beutler, B., Catz, S. D. Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes Biochemical Journal  2007 402:229-239  DOI:10.1042/bj20060950  PMID:17090228
• Johnson, J. L., Ellis, B. A., Munafo, D. B., Brzezinska, A. A., Catz, S. D. Gene transfer and expression in human neutrophils. The phox homology domain of p47(phox) translocates to the plasma membrane but not to the membrane of mature phagosomes BMC Immunology  2006 7:28  DOI:10.1186/1471-2172-7-28  PMID:17150107  PMCID:PMC1712351
• Johnson, J. L., Ellis, B. A., Noack, D., Seabra, M. C., Catz, S. D. The Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphatase Biochemical Journal  2005 391:699-710  DOI:10.1042/bj20050380  PMID:16004602
• Johnson, J. L., Pacquelet, S., Lane, W. S., Eam, B., Catz, S. D. Akt regulates the subcellular localization of the Rab27a-binding protein JFC1 by phosphorylation Traffic  2005 6:667-681  DOI:10.1111/j.1600-0854.2005.00308.x  PMID:15998322
• Hoyal, C. R., Gutierrez, A., Young, B. M., Catz, S. D., Lin, J. H., Tsichlis, P. N., Babior, B. M. Modulation of p47(PHOX) activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase Proceedings of the National Academy of Sciences of the United States of America  2003 100:5130-5135  DOI:10.1073/pnas.1031526100  PMID:12704229  PMCID:PMC154310
• Catz, S. D., Johnson, J. L. BCL-2 in prostate cancer: A minireview Apoptosis  2003 8:29-37  DOI:10.1023/a:1021692801278  PMID:12510149
• Catz, S. D., Babior, B. M., Johnson, J. L. JFC1 is transcriptionally activated by nuclear factor-kappa B and up-regulated by tumour necrosis factor alpha in prostate carcinoma cells Biochemical Journal  2002 367:791-799  DOI:10.1042/bj20020345  PMID:12137562
• Catz, S. D., Johnson, J. L., Babior, B. M. The C2A domain of JFC1 binds to 3 '-phosphorylated phosphoinositides and directs plasma membrane association in living cells Proceedings of the National Academy of Sciences of the United States of America  2002 99:11652-11657  DOI:10.1073/pnas.172382799  PMID:12189202  PMCID:PMC129324
• Catz, S. D., Johnson, J. L. Transcriptional regulation of BCL-2 by nuclear factor kappa B and its significance in prostate cancer Oncogene  2001 20:7342-7351  DOI:10.1038/sj.onc.1204926  PMID:11704864
• Catz, S. D., Johnson, J. L., Babior, B. M. Characterization of the nucleotide-binding capacity and the ATPase activity of the PIP3-binding protein JFC1 Proceedings of the National Academy of Sciences of the United States of America  2001 98:11230-11235  DOI:10.1073/pnas.191369598  PMID:11553774  PMCID:PMC58712
• Berkowitz, J. K. M., Catz, S. D., Johnson, J. L., Ruedi, J. M., Thon, V., Babior, B. M. JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase Journal of Biological Chemistry  2001 276:18855-18862  DOI:10.1074/jbc.M011167200  PMID:11278853
• Catz, S. D., Speziale, E. H., Sterin-Speziale, N. B. Polyphosphoinositide synthesis in human neutrophils - effects of a low metabolic energy state Prostaglandins & Other Lipid Mediators  1998 55:245-264  DOI:10.1016/s0090-6980(98)00021-5  PMID:9644115
• Catz, S. D., SterinSpeziale, N. B. Bradykinin stimulates phosphoinositide turnover and phospholipase C but not phospholipase D and NADPH oxidase in human neutrophils Journal of Leukocyte Biology  1996 59:591-597  PMID:8613709
• Peralta, J., Reides, C., Garcia, S., Llesuy, S., Pargament, G., Carreras, M. C., Catz, S., Poderoso, J. J. Oxidative stress in rodent closed duodenal loop pancreatitis International Journal of Pancreatology  1996 19:61-69  PMID:8656029
• Catz, S. D., Carreras, M. C., Poderoso, J. J. Nitric oxide synthase inhibitors decrease human polymorphonuclear leukocyte luminol-dependent chemiluminescence Free Radical Biology and Medicine  1995 19:741-748  DOI:10.1016/0891-5849(95)00065-6  PMID:8582646
• Kahane, V. L., Cutrin, J. C., Setton, C. P., Fernandez, M. D., Catz, S. D., Sterinspeziale, N. B. Biochemical and morphological-changes in the developing kidney Biology of the Neonate  1995 68:141-152  PMID:8534774
• Carreras, M. C., Catz, S. D., Pargament, G. A., Delbosco, C. G., Poderoso, J. J. Decreased production of nitric oxide by human neutrophils during septic multiple organ dysfunction syndrome. Comparison with endotoxin and cytokine effects on normal cells Inflammation  1994 18:151-161  DOI:10.1007/bf01534556  PMID:8070900
• Carreras, M. C., Pargament, G. A., Catz, S. D., Poderoso, J. J., Boveris, A. Kinetics of nitric oxide and hydrogen peroxide production and formation of peroxynitrite during the respiratory burst of human neutrophils FEBS Letters  1994 341:65-68  DOI:10.1016/0014-5793(94)80241-6  PMID:8137924
• Hoschoian, J. C., Catz, S. D., Borruel, M. A., Wikinski, R. L., Rodriguez, M. P. Evaluation of the blood components considered as risk predictors in coronary heart-disease Medicina-Buenos Aires  1993 53:13-20  PMID:8246725