Cancer Biology Academic Department uri icon

The overall goal of the research in the Department of Cancer Biology at the Scripps Florida campus is to understand the molecular pathogenesis of cancer, with a special focus on signaling pathways directed by oncogenes and tumor suppressors that control cell division, growth, survival, differentiation and metastasis, as well as those that modify the response to therapeutics. The Department, launched in 2006, has developed close research ties with the La Jolla campus.

The Cancer Biology faculty uses a variety of state-of-the-art technologies for target discovery and validation; pre-clinical models have also been developed to evaluate the efficacy of new leads in cancer prevention and therapeutics. While investigators are interested in the molecular underpinnings of all of the major human malignancies, they have special interests in breast, lung, ovarian, and prostate cancer, and in multiple myeloma, leukemia, lymphoma and melanoma. They also have exciting programs evaluating the interplay between cancer and the immune system, and the relationships between aging and cancer.

One of the many strengths of Scripps Florida is the availability of high-throughput technologies that allow Investigators to rapidly develop potential lead compounds by using both genetic and small molecule screens. Collaborations with the major Cancer Centers in the State of Florida and with the La Jolla campus allow identified leads to quickly move forward into translational and clinical studies.