recent publications
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academic article
- Tan, Y. X., Peters, D. S., Walsh, S. I., Holcomb, M., Santos-Martins, D., Forli, S., Romesberg, F. E. Initial Analysis of the Arylomycin D Antibiotics Journal of Natural Products 2020 83:2112-2121 DOI:10.1021/acs.jnatprod.9b01174 PMID:32614583
- Fischer, E. C., Hashimoto, K., Zhang, Y., Feldman, A. W., Dien, V. T., Karadeema, R. J., Adhikary, R., Ledbetter, M. P., Krishnamurthy, R., Romesberg, F. E. New codons for efficient production of unnatural proteins in a semisynthetic organism Nature Chemical Biology 2020 16:570-576 DOI:10.1038/s41589-020-0507-z PMID:32251411
- Ledbetter, M. P., Craig, J. M., Karadeema, R. J., Noakes, M. T., Kim, H. C., Abell, S. J., Huang, J. R., Anderson, B. A., Krishnamurthy, R., Gundlach, J. H., Romesberg, F. E. Nanopore sequencing of an expanded genetic alphabet reveals high-fidelity replication of a predominantly hydrophobic unnatural base pair Journal of the American Chemical Society 2020 142:2110-2114 DOI:10.1021/jacs.9b09808 PMID:31985216
- Shao, Q., Chen, T., Sheng, K., Liu, Z., Zhang, Z., Romesberg, F. E. Selection of aptamers with large hydrophobic 2'-substituents Journal of the American Chemical Society 2020 142:2125-2128 DOI:10.1021/jacs.9b10538 PMID:31961667
- Zhou, A. X. Z., Sheng, K., Feldman, A. W., Romesberg, F. E. Progress toward eukaryotic semisynthetic organisms: translation of unnatural codons Journal of the American Chemical Society 2019 141:20166-20170 DOI:10.1021/jacs.9b09080
- Feldman, A. W., Dien, V. T., Karadeema, R. J., Fischer, E. C., You, Y., Anderson, B. A., Krishnamurthy, R., Chen, J. S., Li, L., Romesberg, F. E. Optimization of replication, transcription, and translation in a semi-synthetic organism Journal of the American Chemical Society 2019 141:10644-10653 DOI:10.1021/jacs.9b02075 PMID:31241334
- Adhikary, R., Zimmermann, J., Stanfield, R. L., Wilson, I. A., Yu, W., Oda, M., Romesberg, F. E. Structure and dynamics of stacking interactions in an antibody binding site Biochemistry 2019 58:2987-2995 DOI:10.1021/acs.biochem.9b00119 PMID:31243995
- Walsh, S. I., Peters, D. S., Smith, P. A., Craney, A., Dix, M. M., Cravatt, B. F., Romesberg, F. E. Inhibition of protein secretion in Escherichia coli and sub-MIC effects of arylomycin antibiotics Antimicrobial Agents and Chemotherapy 2019 63:e01253-18 DOI:10.1128/aac.01253-18 PMID:30420476 PMCID:PMC6355593
- Romesberg, F. E. Synthetic Biology: The chemist's approach Israel Journal of Chemistry 2019 59:91-94 DOI:10.1002/ijch.201900014
- Ledbetter, M. P., Malyshev, D. A., Romesberg, F. E. Site-specific labeling of DNA via PCR with an expanded genetic alphabet Methods in Molecular Biology 2019 1973:193-212 DOI:10.1007/978-1-4939-9216-4_13 PMID:31016704
- Dien, V. T., Holcomb, M., Feldman, A. W., Fischer, E. C., Dwyer, T. J., Romesberg, F. E. Progress toward a semi-synthetic organism with an unrestricted expanded genetic alphabet Journal of the American Chemical Society 2018 140:16115-16123 DOI:10.1021/jacs.8b08416 PMID:30418780
- Ledbetter, M. P., Romesberg, F. E. Editorial overview: Expanding the genetic alphabet and code Current Opinion in Chemical Biology 2018 46:A1-A2 DOI:10.1016/j.cbpa.2018.09.007 PMID:30270151
- Dien, V. T.*, Morris, S. E.*, Karadeemal, R. J., Romesberg, F. E. Expansion of the genetic code via expansion of the genetic alphabet Current Opinion in Chemical Biology 2018 46:196-202 DOI:10.1016/j.cbpa.2018.08.009 PMID:30205312 (* = equal contribution)
- White, R. F., Steele, L., O'Callaghan, J. P., Sullivan, K., Binns, J. H., Golomb, B. A., Bloom, F. E., Bunker, J. A., Crawford, F., Graves, J. C., Hardie, A., Klimas, N., et al. Recent research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effects of toxicant exposures during deployment Cortex 2016 74:449-475 DOI:10.1016/j.cortex.2015.08.022 PMID:26493934 PMCID:PMC4724528
- Bloom, F. E. Mentored and inspired by Mimo: A tribute to Erminio Costa Neuropharmacology 2011 60:1003-1006 DOI:10.1016/j.neuropharm.2010.09.019 PMID:20869374
- Sutcliffe, J. G., Hedlund, P. B., Thomas, E. A., Bloom, F. E., Hilbush, B. S. Peripheral reduction of beta-amyloid is sufficient to reduce brain beta-amyloid: Implications for alzheimer's disease Journal of Neuroscience Research 2011 89:808-814 DOI:10.1002/jnr.22603 PMID:21374699
- Bloom, F. E. The catecholamine neuron: Historical and future perspectives Progress in Neurobiology 2010 90:75-81 DOI:10.1016/j.pneurobio.2009.10.014 PMID:19853013
- Broide, R. S., Redwine, J. M., Aftahi, N., Young, W., Bloom, F. E., Winrow, C. J. Distribution of histone deacetylases 1-11 in the rat brain Journal of Molecular Neuroscience 2007 31:47-58 DOI:10.1385/jmn/31:01:47 PMID:17416969
- Bloom, F. E., Morrison, J. H., Young, W. G. Neuroinformatics: A new tool for studying the brain Journal of Affective Disorders 2006 92:133-138 DOI:10.1016/j.jad.2005.12.043 PMID:16488481
- Jacobsen, J. S., Wu, C. C., Redwine, J. M., Comery, T. A., Arias, R., Bowlby, M., Martone, R., Morrison, J. H., Pangalos, M. N., Reinhart, P. H., Bloom, F. E. Early-onset behavioral and synaptic deficits in a mouse model of alzheimer's disease Proceedings of the National Academy of Sciences of the United States of America 2006 103:5161-5166 DOI:10.1073/pnas.0600948103 PMID:16549764 PMCID:PMC1405622
- Zapala, M. A., Hovatta, I., Ellison, J. A., Wodicka, L., Del Rio, J. A., Tennant, R., Tynan, W., Broide, R. S., Helton, R., Stoveken, B. S., Winrow, C., Lockhart, D. J., et al. Adult mouse brain gene expression patterns bear an embryologic imprint Proceedings of the National Academy of Sciences of the United States of America 2005 102:10357-10362 DOI:10.1073/pnas.0503357102 PMID:16002470 PMCID:PMC1173363
- Bloom, F. E., Reilly, J. F., Redwine, J. M., Wu, C. C., Young, W. G., Morrison, J. H. Mouse models of human neurodegenerative disorders - requirements for medication development Archives of Neurology 2005 62:185-187 DOI:10.1001/archneur.62.2.185 PMID:15710845
- Wu, C. C., Chawla, F., Games, D., Rydel, R. E., Freedman, S., Schenk, D., Young, W. G., Morrison, J. H., Bloom, F. E. Selective vulnerability of dentate granule cells prior to amyloid deposition in pdapp mice: Digital morphometric analyses Proceedings of the National Academy of Sciences of the United States of America 2004 101:7141-7146 DOI:10.1073/pnas.0402147101 PMID:15118092 PMCID:PMC406479
- Wu, C. C., Reilly, J. F., Young, W. G., Morrison, J. H., Bloom, F. E. High-throughput morphometric analysis of individual neurons Cerebral Cortex 2004 14:543-554 DOI:10.1093/cercor/bhh016 PMID:15054070
- Broide, R. S., Trembleau, A., Ellison, J. A., Cooper, J., Lo, D., Young, W. G., Morrison, J. H., Bloom, F. E. Standardized quantitative in situ hybridization using radioactive oligonucleotide probes for detecting relative levels of mrna transcripts verified by real-time pcr Brain Research 2004 1000:211-222 DOI:10.1016/j.brainres.2003.11.069 PMID:15053970
- Engelmann, M., Wolf, G., Putzke, J., Bloom, F. E., Raber, J., Landgraf, R., Spina, M. G., Horn, T. F. W. Nitric oxide is not involved in the control of vasopressin release during acute forced swimming in rats Amino Acids 2004 26:37-43 DOI:10.1007/s00726-003-0040-x PMID:14752614
- Hokfelt, T., Bartfai, T., Bloom, F. Neuropeptides: Opportunities for drug discovery Lancet Neurology 2003 2:463-472 DOI:10.1016/s1474-4422(03)00482-4 PMID:12878434
- Reilly, J. F., Games, D., Rydel, R. E., Freedman, S., Schenk, D., Young, W. G., Morrison, J. H., Bloom, F. E. Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model Proceedings of the National Academy of Sciences of the United States of America 2003 100:4837-4842 DOI:10.1073/pnas.0330745100 PMID:12697936 PMCID:PMC153642
- Redwine, J. M., Kosofsky, B., Jacobs, R. E., Games, D., Reilly, J. F., Morrison, J. H., Young, W. G., Bloom, F. E. Dentate gyrus volume is reduced before onset of plaque formation in pdapp mice: A magnetic resonance microscopy and stereologic analysis Proceedings of the National Academy of Sciences of the United States of America 2003 100:1381-1386 DOI:10.1073/pnas.242746599 PMID:12552120 PMCID:PMC298781
- Sanna, P. P., Cammalleri, M., Berton, F., Simpson, C., Lutjens, R., Bloom, F. E., Francesconi, W. Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region Journal of Neuroscience 2002 22:3359-3365 PMID:11978812
- Bloom, F. E. Publishing (whatever that means) neuroscience in the new millennium Brain Research 2000 886:1-4 DOI:10.1016/s0006-8993(00)02754-2 PMID:11119682
- Sanna, P. P., Berton, F., Cammalleri, M., Tallent, M. K., Siggins, G. R., Bloom, F. E., Francesconi, W. A role for Src kinase in spontaneous epileptiform activity in the CA3 region of the hippocampus Proceedings of the National Academy of Sciences of the United States of America 2000 97:8653-8657 DOI:10.1073/pnas.140219097 PMID:10890901 PMCID:PMC27003
- Nimchinsky, E. A., Young, W. G., Yeung, G., Shah, R. A., Gordon, J. W., Bloom, F. E., Morrison, J. H., Hof, P. R. Differential vulnerability of oculomotor, facial, and hypoglossal nuclei in g86r superoxide dismutase transgenic mice Journal of Comparative Neurology 2000 416:112-125 DOI:10.1002/(sici)1096-9861(20000103)416:1<112::aid-cne9>3.0.co;2-k PMID:10578106
- Weed, M. R., Taffe, M. A., Polis, I., Roberts, A. C., Robbins, T. W., Koob, G. F., Bloom, F. E., Gold, L. H. Performance norms for a rhesus monkey neuropsychological testing battery: acquisition and long-term performance Cognitive Brain Research 1999 8:185-201 DOI:10.1016/s0926-6410(99)00020-8 PMID:10556598
- Rende, M., Morales, M., Brizi, E., Bruno, R., Bloom, F., Sanna, P. P. Modulation of serotonin 5-HT3 receptor expression in injured adult rat spinal cord motoneurons Brain Research 1999 823:234-240 DOI:10.1016/s0006-8993(99)01180-4 PMID:10095035
- Polich, J., Bloom, F. E. P300, alcoholism heritability, and stimulus modality Alcohol 1999 17:149-156 DOI:10.1016/s0741-8329(98)00047-0 PMID:10064383
- Morales, R., Battenberg, E., Bloom, F. E. Distribution of neurons expressing immunoreactivity for the 5ht(3) receptor subtype in the rat brain and spinal cord Journal of Comparative Neurology 1998 402:385-401 PMID:9853906
- Akwa, Y., Hassett, D. E., Eloranta, M. L., Sandberg, K., Masliah, E., Powell, H., Whitton, J. L., Bloom, F. E., Campbell, I. L. Transgenic expression of ifn-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration Journal of Immunology 1998 161:5016-5026 PMID:9794439
- Koob, G. F., Sanna, P. P., Bloom, F. E. Neuroscience of addiction Neuron 1998 21:467-476 DOI:10.1016/s0896-6273(00)80557-7 PMID:9768834
- Morales, M., Criado, J. R., Sanna, P. P., Henriksen, S. J., Bloom, F. E. Acute ethanol induces c-fos immunoreactivity in GABAergic neurons of the central nucleus of the amygdala Brain Research 1998 798:333-336 DOI:10.1016/s0006-8993(98)00457-0 PMID:9666163
- Raber, J., Sorg, O., Horn, T. F. W., Yu, N., Koob, G. F., Campbell, I. L., Bloom, F. E. Inflammatory cytokines: Putative regulators of neuronal and neuro-endocrine function Brain Research Reviews 1998 26:320-326 DOI:10.1016/s0165-0173(97)00041-6 PMID:9651548
- Woldorff, M. G., Hillyard, S. A., Gallen, C. C., Hampson, S. R., Bloom, F. E. Magnetoencephalographic recordings demonstrate attentional modulation of mismatch-related neural activity in human auditory cortex Psychophysiology 1998 35:283-292 DOI:10.1017/s0048577298961601 PMID:9564748
- Bloom, F. E., Morales, M. The central 5-ht3 receptor in cns disorders Neurochemical Research 1998 23:653-659 DOI:10.1023/a:1022486705184 PMID:9566603
- Gold, L. H., Fox, H. S., Henriksen, S. J., Buchmeier, M. J., Weed, M. R., Taffe, M. A., Huitron-Resendiz, S., Horn, T. F. W., Bloom, F. E. Longitudinal analysis of behavioral, neurophysiological, viral and immunological effects of SIV infection in rhesus monkeys Journal of Medical Primatology 1998 27:104-112 DOI:10.1111/j.1600-0684.1998.tb00234.x PMID:9747951
- Begleiter, H., Porjesz, B., Reich, T., Edenberg, H. J., Goate, A., Blangero, J., Almasy, L., Foroud, T., Van Eerdewegh, P., Polich, J., Rohrbaugh, J., Kuperman, S., et al. Quantitative trait loci analysis of human event-related brain potentials: P3 voltage Evoked Potentials-Electroencephalography and Clinical Neurophysiology 1998 108:244-250 DOI:10.1016/s0168-5597(98)00002-1
- De Lecea, L., Kilduff, T. S., Peyron, C., Gao, X. B., Foye, P. E., Danielson, P. E., Fukuhara, C., Battenberg, E. L. F., Gautvik, V. T., Bartlett, F. S., Frankel, W. N., van den Pol, A. N., et al. The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity Proceedings of the National Academy of Sciences of the United States of America 1998 95:322-327 DOI:10.1073/pnas.95.1.322 PMID:9419374
- Yu, N. C., Zhang, X. H., Magistretti, P. J., Bloom, F. E. Il-1-alpha and tnf-alpha differentially regulate cd4 and mac-1 expression in mouse microglia Neuroimmunomodulation 1998 5:42-52 DOI:10.1159/000026325 PMID:9698257
- Burton, F. H., Forss-Petter, S., Battenberg, E., Bloom, F. E., Sutcliffe, J. G. Lethal psychomotor abnormalities in mice caused by a neural cholera toxin transgene Transgenics 1998 2:249-257
- Trembleau, A., Bloom, F. E. Subcellular localization of tyrosine hydroxylase (th) gene transcripts: New insights into the pattern of th gene expression in the locus coeruleus under pharmacological stimulation Biology of the Cell 1998 90:39-51 DOI:10.1016/s0248-4900(98)80231-1 PMID:9691425
- Raber, J., Oshea, R. D., Bloom, F. E., Campbell, I. L. Modulation of hypothalamic-pituitary-adrenal function by transgenic expression of interleukin-6 in the cns of mice Journal of Neuroscience 1997 17:9473-9480 PMID:9391003
- Jacobson, S., Henriksen, S. J., ProsperoGarcia, O., Phillips, T. R., Elder, J. H., Young, W. G., Bloom, F. E., Fox, H. S. Cortical neuronal cytoskeletal changes associated with fiv infection Journal of Neurovirology 1997 3:283-289 PMID:9291236
- Stalder, A. K., Pagenstecher, A., Yu, N. C., Kincaid, C., Chiang, C. S., Hobbs, M. V., Bloom, F. E., Campbell, I. L. Lipopolysaccharide-induced il-12 expression in the central nervous system and cultured astrocytes and microglia Journal of Immunology 1997 159:1344-1351 PMID:9233631
- Sorg, O., Horn, T. F. W., Yu, N. C., Gruol, D. L., Bloom, F. E. Inhibition of astrocyte glutamate uptake by reactive oxygen species: Role of antioxidant enzymes Molecular Medicine 1997 3:431-440 PMID:9260155 PMCID:PMC2230215
- Cunningham, E. T., Stalder, A. K., Sanna, P. P., Liu, S. S., Bloom, F. E., Howes, E. L., Campbell, I. L., Margolis, T. P. Distribution of tumor necrosis factor receptor messenger rna in normal and herpes simplex virus infected trigeminal ganglia in the mouse Brain Research 1997 758:99-106 DOI:10.1016/s0006-8993(97)00169-8 PMID:9203538
- Morales, M., Bloom, F. E. The 5-HT(3) receptor is present in different subpopulations of GABAergic neurons in the rat telencephalon Journal of Neuroscience 1997 17:3157-3167 PMID:9096150
- Raber, J., Koob, G. F., Bloom, F. E. Interferon-alpha and transforming growth factor-beta(1) regulate corticotropin-releasing factor release from the amygdala: Comparison with the hypothalamic response Neurochemistry International 1997 30:455-463 DOI:10.1016/s0197-0186(96)00082-4 PMID:9106261
- Gallen, C. C., Tecoma, E., Iragui, V., Sobel, D. F., Schwartz, B. J., Bloom, F. E. Magnetic source imaging of abnormal low-frequency magnetic activity in presurgical evaluations of epilepsy Epilepsia 1997 38:452-460 DOI:10.1111/j.1528-1157.1997.tb01735.x PMID:9118851
- Raber, J., Mehta, P. P., Kreifeldt, M., Parsons, L. H., Weiss, F., Bloom, F. E., Wilson, M. C. Coloboma hyperactive mutant mice exhibit regional and transmitter-specific deficits in neurotransmission Journal of Neurochemistry 1997 68:176-186 DOI:10.1046/j.1471-4159.1997.68010176.x PMID:8978724
- Ryabinin, A. E., Criado, J. R., Henriksen, S. J., Bloom, F. E., Wilson, M. C. Differential sensitivity of c-fos expression in hippocampus and other brain regions to moderate and low doses of alcohol Molecular Psychiatry 1997 2:32-43 DOI:10.1038/sj.mp.4000206 PMID:9154216
- Cunningham, E. T., Stalder, A., Sanna, P. P., Liu, S. S., Bloom, F. E., Howes, E. L., Campbell, I. L., Margolis, T. P. Localization of tumor necrosis factor receptor messenger rna in normal and herpes simplex virus infected mouse eyes Investigative Ophthalmology & Visual Science 1997 38:9-15 PMID:9008625
- Fox, H. S., Gold, L. H., Henriksen, S. J., Bloom, F. E. Simian immunodeficiency virus: A model for neuroaids Neurobiology of Disease 1997 4:265-274 DOI:10.1006/nbdi.1997.0159 PMID:9361303
- Phillips, T. R., ProsperoGarcia, O., Wheeler, D. W., Wagaman, P. C., Lerner, D. L., Fox, H. S., Whalen, L. R., Bloom, F. E., Elder, J. H., Henriksen, S. J. Neurologic dysfunctions caused by a molecular clone of feline immunodeficiency virus, fiv-ppr Journal of Neurovirology 1996 2:388-396 DOI:10.3109/13550289609146904 PMID:8972420
- Bloom, F. E. The multidimensional database and neuroinformatics requirements for molecular and cellular neuroscience Neuroimage 1996 4:S12-S13 DOI:10.1006/nimg.1996.0042 PMID:9345517
- ProsperoGarcia, O., Gold, L. H., Fox, H. S., Polis, I., Koob, G. F., Bloom, F. E., Henriksen, S. J. Microglia-passaged simian immunodeficiency virus induces neurophysiological abnormalities in monkeys Proceedings of the National Academy of Sciences of the United States of America 1996 93:14158-14163 DOI:10.1073/pnas.93.24.14158 PMID:8943077
- Mathiasen, J. R., MaciejewskiLenoir, D., Bloom, F. E., Sladek, C. D. Increased vasopressin secretion from hypothalamic cultures following administration of exogenous vasopressin mrna Experimental Neurology 1996 141:165-172 DOI:10.1006/exnr.1996.0150 PMID:8812149
- Heinrichs, S. C., StenzelPoore, M. P., Gold, L. H., Battenberg, E., Bloom, F. E., Koob, G. F., Vale, W. W., Pich, E. M. Learning impairment in transgenic mice with central overexpression of corticotropin-releasing factor Neuroscience 1996 74:303-311 DOI:10.1016/0306-4522(96)00140-6 PMID:8865183
- Morales, M., Battenberg, E., deLecea, L., Bloom, F. E. The type 3 serotonin receptor is expressed in a subpopulation of gabaergic neurons in the rat neocortex and hippocampus Brain Research 1996 731:199-202 DOI:10.1016/s0006-8993(96)00557-4 PMID:8883870
- Gautvik, K. M., deLecea, L., Gautvik, V. T., Danielson, P. E., Tranque, P., Dopazo, A., Bloom, F. E., Sutcliffe, J. G. Overview of the most prevalent hypothalamus-specific mrnas, as identified by directional tag pcr subtraction Proceedings of the National Academy of Sciences of the United States of America 1996 93:8733-8738 DOI:10.1073/pnas.93.16.8733 PMID:8710940
- Easton, C., Bauer, L. O., Begleiter, H., Reich, T., Nurnberger, J., Conneally, P. M., Crow, R., Kuperman, S., Schuckit, M., Bloom, F. E., Hesselbrock, V., Porjesz, B., et al. Neuropsychological correlates of urine toxicology results Progress in Neuro-Psychopharmacology & Biological Psychiatry 1996 20:969-982 DOI:10.1016/0278-5846(96)00077-2 PMID:8888104
- Weiss, F., Parsons, L. H., Schulteis, G., Hyytia, P., Lorang, M. T., Bloom, F. E., Koob, G. F. Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats Journal of Neuroscience 1996 16:3474-3485 PMID:8627380
- Morales, M., Battenberg, E., deLecea, L., Sanna, P. P., Bloom, F. E. Cellular and subcellular immunolocalization of the type 3 serotonin receptor in the rat central nervous system Molecular Brain Research 1996 36:251-260 DOI:10.1016/0169-328x(96)88406-3 PMID:8965645
- Bloom, F. E. An internet review: The compleat neuroscientist scours the world wide web Science 1996 274:1104-1108 DOI:10.1126/science.274.5290.1104 PMID:8895452
- Raber, J., Bloom, F. E. Arginine vasopressin release by acetylcholine or norepinephrine: Region-specific and cytokine-specific regulation Neuroscience 1996 71:747-759 DOI:10.1016/0306-4522(95)00517-x PMID:8867047
- Trembleau, A., Morales, M., Bloom, F. E. Differential compartmentalization of vasopressin messenger rna and neuropeptide within the rat hypothalamo-neurohypophysial axonal tracts: Light and electron microscopic evidence Neuroscience 1996 70:113-125 DOI:10.1016/0306-4522(95)00328-g PMID:8848117
- Sanna, P. P., deLogu, A., Williamson, R. A., Hom, Y. L., Straus, S. E., Bloom, F. E., Burton, D. R. Protection of nude mice by passive immunization with a type-common human recombinant monoclonal antibody against hsv Virology 1996 215:101-106 DOI:10.1006/viro.1996.0011 PMID:8553581
- Trembleau, A., Bloom, F. E. Spatial segregation of g(alpha s) mrna and vasopressin mrna to distinct domains of the rough endoplasmic reticulum within secretory neurons of the rat hypothalamus Molecular and Cellular Neuroscience 1996 7:17-28 DOI:10.1006/mcne.1996.0002 PMID:8812056
- Trembleau, A., Melia, K. R., Bloom, F. E. Bc1 rna and vasopressin messenger-rna in rat neurohypophysis - axonal compartmentalization and differential regulation during dehydration and rehydration European Journal of Neuroscience 1995 7:2249-2260 DOI:10.1111/j.1460-9568.1995.tb00646.x PMID:8563974
- Sanna, P. P., Delogu, A., Williamson, R. A., Samson, M. E., Altieri, D. C., Bloom, F. E., Burton, D. R. Rapid assay of phage-derived recombinant human Fabs as bispecific antibodies Bio-Technology 1995 13:1221-1224 DOI:10.1038/nbt1195-1221 PMID:9636296
- Yu, N. C., Maciejewskilenoir, D., Bloom, F. E., Magistretti, P. J. Tumor-necrosis-factor-alpha and interleukin-1-alpha enhance glucose-utilization by astrocytes - involvement of phospholipase a(2) Molecular Pharmacology 1995 48:550-558 PMID:7565637
- Trembleau, A., Bloom, F. E. Enhanced sensitivity for light and electron-microscopic in-situ hybridization with multiple simultaneous nonradioactive oligodeoxynucleotide probes Journal of Histochemistry & Cytochemistry 1995 43:829-841 PMID:7622844
- Lerner, D. L., Wagaman, P. C., Phillips, T. R., Prosperogarcia, O., Henriksen, S. J., Fox, H. S., Bloom, F. E., Elder, J. H. Increased mutation frequency of feline immunodeficiency virus lacking functional deoxyuridine-triphosphatase Proceedings of the National Academy of Sciences of the United States of America 1995 92:7480-7484 DOI:10.1073/pnas.92.16.7480 PMID:7638216
- Sanna, P. P., Williamson, R. A., Delogu, A., Bloom, F. E., Burton, D. R. Directed selection of recombinant human monoclonal-antibodies to herpes-simplex virus glycoproteins from phage display libraries Proceedings of the National Academy of Sciences of the United States of America 1995 92:6439-6443 DOI:10.1073/pnas.92.14.6439 PMID:7604009
- Ryabinin, A. E., Cole, M., Bloom, F. E., Wilson, M. C. Exposure of neonatal rats to alcohol by vapor inhalation demonstrates specificity of microcephaly and purkinje-cell loss but not astrogliosis Alcoholism-Clinical and Experimental Research 1995 19:784-791 DOI:10.1111/j.1530-0277.1995.tb01583.x PMID:7573809
- Bloom, F. E. Gene-expression from recombinant viral vectors in the central-nervous-system after blood-brain-barrier disruption - comment Neurosurgery 1995 36:970-970
- Geiger, K. D., Gurushanthaiah, D., Howes, E. L., Lewandowski, G. A., Reed, J. C., Bloom, F. E., Sarvetnick, N. E. Cytokine-mediated survival from lethal herpes-simplex virus-infection - role of programmed neuronal death Proceedings of the National Academy of Sciences of the United States of America 1995 92:3411-3415 DOI:10.1073/pnas.92.8.3411 PMID:7724576
- Raber, J., Koob, G. F., Bloom, F. E. Interleukin-2 (il-2) induces corticotropin-releasing factor (crf) release from the amygdala and involves a nitric oxide-mediated signaling - comparison with the hypothalamic response Journal of Pharmacology and Experimental Therapeutics 1995 272:815-824 PMID:7853199
- Bloom, F. E. Neuroscience knowledge management - slow change so far Trends in Neurosciences 1995 18:48-49 DOI:10.1016/0166-2236(95)93864-t PMID:7537402
- Sanna, P. P., Weiss, F., Samson, M. E., Bloom, F. E., Pich, E. M. Rapid induction of tumor-necrosis-factor-alpha in the cerebrospinal-fluid after intracerebroventricular injection of lipopolysaccharide revealed by a sensitive capture immuno-pcb assay Proceedings of the National Academy of Sciences of the United States of America 1995 92:272-275 DOI:10.1073/pnas.92.1.272 PMID:7816831
- Ryabinin, A. E., Melia, K. R., Cole, M., Bloom, F. E., Wilson, M. C. Alcohol selectively attenuates stress-induced c-fos expression in rat hippocampus Journal of Neuroscience 1995 15:721-730 PMID:7823175
- Henriksen, S. J., Prospero-Garcia, O., Phillips, T. R., Fox, H. S., Bloom, F. E., Elder, J. H. Feline immunodeficiency virus as a model for study of lentivirus infection of the central nervous system Current Topics in Microbiology and Immunology 1995 202:167-186 PMID:7587362
- Prosperogarcia, O., Herold, N., Phillips, T. R., Elder, J. H., Bloom, F. E., Henriksen, S. J. Sleep patterns are disturbed in cats infected with feline immunodeficiency virus Proceedings of the National Academy of Sciences of the United States of America 1994 91:12947-12951 DOI:10.1073/pnas.91.26.12947 PMID:7809152
- Melia, K. R., Trembleau, A., Oddi, R., Sanna, P. P., Bloom, F. E. Detection and regulation of tyrosine-hydroxylase messenger-rna in catecholaminergic terminal fields - possible axonal compartmentalization Experimental Neurology 1994 130:394-406 DOI:10.1006/exnr.1994.1219 PMID:7532593
- Lewandowski, G., Hobbs, M. V., Bloom, F. E. Alteration of intracerebral cytokine production in mice infected with herpes-simplex virus type-1 and type-2 Journal of Neuroimmunology 1994 55:23-34 DOI:10.1016/0165-5728(94)90143-0 PMID:7962482
- Raber, J., Bloom, F. E. Il-2 induces vasopressin release from the hypothalamus and the amygdala - role of nitric oxide-mediated signaling Journal of Neuroscience 1994 14:6187-6195 PMID:7523633
- Melia, K. R., Ryabinin, A. E., Schroeder, R., Bloom, F. E., Wilson, M. C. Induction and habituation of immediate-early gene-expression in rat-brain by acute and repeated restraint stress Journal of Neuroscience 1994 14:5929-5938 PMID:7931554
- Alexander, J. E., Polich, J., Bloom, F. E., Bauer, L. O., Kuperman, S., Rohrbaugh, J., Morzorati, S., Oconnor, S. J., Porjesz, B., Begleiter, H. P300 from an auditory oddball task - inter-laboratory consistency International Journal of Psychophysiology 1994 17:35-46 DOI:10.1016/0167-8760(94)90053-1 PMID:7961052
- Phillips, T. R., Prosperogarcia, O., Puaoi, D. L., Lerner, D. L., Fox, H. S., Olmsted, R. A., Bloom, F. E., Henriksen, S. J., Elder, J. H. Neurological abnormalities associated with feline immunodeficiency virus-infection Journal of General Virology 1994 75:979-987 DOI:10.1099/0022-1317-75-5-979 PMID:8176384
- Raber, J., Pich, E. M., Koob, G. F., Bloom, F. E. Il-1-beta potentiates the acetylcholine-induced release of vasopressin from the hypothalamus in-vitro, but not from the amygdala Neuroendocrinology 1994 59:208-217 DOI:10.1159/000126661 PMID:8159270
- Yang, T. T., Gallen, C. C., Ramachandran, V. S., Cobb, S., Schwartz, B. J., Bloom, F. E. Noninvasive detection of cerebral plasticity in adult human somatosensory cortex Neuroreport 1994 5:701-704 DOI:10.1097/00001756-199402000-00010 PMID:8199341
- Gallen, C. C., Schwartz, B., Rieke, K., Pantev, C., Sobel, D., Hirschkoff, E., Bloom, F. E. Intrasubject reliability and validity of somatosensory source localization using a large array biomagnetometer Electroencephalography and Clinical Neurophysiology 1994 90:145-156 DOI:10.1016/0013-4694(94)90006-x PMID:7510629
- Burioni, R., Williamson, R. A., Sanna, P. P., Bloom, F. E., Burton, D. R. Recombinant human fab to glycoprotein-d neutralizes infectivity and prevents cell-to-cell transmission of herpes-simplex virus-1 and virus-2 in-vitro Proceedings of the National Academy of Sciences of the United States of America 1994 91:355-359 DOI:10.1073/pnas.91.1.355 PMID:8278393
- Godbout, M., Erlander, M. G., Hasel, K. W., Danielson, P. E., Wong, K. K., Battenberg, E. L. F., Foye, P. E., Bloom, F. E., Sutcliffe, J. G. 1G5: a calmodulin-binding, vesicle-associated, protein kinase-like protein enriched in forebrain neurites Journal of Neuroscience 1994 14:1-13 PMID:8283228
- Trembleau, A., Morales, M., Bloom, F. E. Aggregation of vasopressin messenger-rna in a subset of axonal swellings of the median-eminence and posterior pituitary - light and electron-microscopic evidence Journal of Neuroscience 1994 14:39-53 PMID:8283246
- Danielson, P. E., Forsspetter, S., Battenberg, E. L. F., Delecea, L., Bloom, F. E., Sutcliffe, J. G. Four structurally distinct neuron-specific olfactomedin-related glycoproteins produced by differential promoter utilization and alternative mRNA splicing from a single gene Journal of Neuroscience Research 1994 38:468-478 DOI:10.1002/jnr.490380413 PMID:7932877
- Polich, J., Pollock, V. E., Bloom, F. E. Metaanalysis of p300 amplitude from males at risk for alcoholism Psychological Bulletin 1994 115:55-73 DOI:10.1037//0033-2909.115.1.55 PMID:8310100
- Bloom, F. E., Young, W. G. New solutions for neuroscience communications are still needed Neuroscience: From the Molecular to the Cognitive 1994 100:275-281 PMID:7938529
- Moses, A. V., Bloom, F. E., Pauza, C. D., Nelson, J. A. Human-immunodeficiency-virus infection of human brain capillary endothelial-cells occurs via a cd4 galactosylceramide-independent mechanism Proceedings of the National Academy of Sciences of the United States of America 1993 90:10474-10478 DOI:10.1073/pnas.90.22.10474 PMID:7504264
- Weiss, F., Lorang, M. T., Bloom, F. E., Koob, G. F. Oral alcohol self-administration stimulates dopamine release in the rat nucleus-accumbens - genetic and motivational determinants Journal of Pharmacology and Experimental Therapeutics 1993 267:250-258 PMID:8229752
- Woldorff, M. G., Gallen, C. C., Hampson, S. A., Hillyard, S. A., Pantev, C., Sobel, D., Bloom, F. E. Modulation of early sensory processing in human auditory-cortex during auditory selective attention Proceedings of the National Academy of Sciences of the United States of America 1993 90:8722-8726 DOI:10.1073/pnas.90.18.8722 PMID:8378354
- Gallen, C. C., Bloom, F. E. Brain imaging - mapping the brain with msi Current Biology 1993 3:522-524 DOI:10.1016/0960-9822(93)90046-q PMID:15335693
- Sanna, P. P., Folsom, D. P., Barizo, M. J., Hirsch, M. D., Melia, K. R., Maciejewskilenoir, D., Bloom, F. E. Chronic ethanol intake decreases vasopressin messenger-rna content in the rat hypothalamus - a pcr study Molecular Brain Research 1993 19:241-245 DOI:10.1016/0169-328x(93)90035-n PMID:8412569
- Gallen, C. C., Roberts, D. W., Sobel, D. F., Waltz, T., Crandall, P. H., Aung, M., Copeland, B., Schwartz, B. J., Hirschkoff, E. C., Bloom, F. E. Noninvasive presurgical neuromagnetic mapping of somatosensory cortex Neurosurgery 1993 33:260-268 PMID:8367048
- Sobel, D. F., Gallen, C. C., Schwartz, B. J., Waltz, T. A., Copeland, B., Yamada, S., Hirschkoff, E. C., Bloom, F. E. Locating the central sulcus - comparison of mr anatomic and magnetoencephalographic functional methods American Journal of Neuroradiology 1993 14:915-925 PMID:8352165
- Yang, T. T., Gallen, C. C., Schwartz, B. J., Bloom, F. E. Noninvasive somatosensory homunculus mapping in humans by using a large-array biomagnetometer Proceedings of the National Academy of Sciences of the United States of America 1993 90:3098-3102 DOI:10.1073/pnas.90.7.3098 PMID:8464929
- Sanna, P. P., Celio, M. R., Bloom, F. E., Rende, M. Presumptive renshaw cells contain decreased calbindin during recovery from sciatic-nerve lesions Proceedings of the National Academy of Sciences of the United States of America 1993 90:3048-3052 DOI:10.1073/pnas.90.7.3048 PMID:8464922
- Bloom, F. E. Advancing a neurodevelopmental origin for schizophrenia Archives of General Psychiatry 1993 50:224-227 PMID:8439244
- Lewandowski, G. A., Lo, D., Bloom, F. E. Interference with major histocompatibility complex class-ii-restricted antigen presentation in the brain by herpes-simplex virus type-1 - a possible mechanism of evasion of the immune-response Proceedings of the National Academy of Sciences of the United States of America 1993 90:2005-2009 DOI:10.1073/pnas.90.5.2005 PMID:8095338
- Maciejewskilenoir, D., Jirikowski, G. F., Sanna, P. P., Bloom, F. E. Reduction of exogenous vasopressin rna poly(a) tail length increases its effectiveness in transiently correcting diabetes-insipidus in the brattleboro rat Proceedings of the National Academy of Sciences of the United States of America 1993 90:1435-1439 DOI:10.1073/pnas.90.4.1435 PMID:7679506
- Sanna, P. P., Keyser, K. T., Celio, M. R., Karten, H. J., Bloom, F. E. Distribution of parvalbumin immunoreactivity in the vertebrate retina Brain Research 1993 600:141-150 DOI:10.1016/0006-8993(93)90412-g PMID:8422581
- Sanna, P. P., Jirikowski, G. F., Lewandowski, G. A., Bloom, F. E. Applications of dapi cytochemistry to neurobiology Biotechnic & Histochemistry 1992 67:346-350 DOI:10.3109/10520299209110047 PMID:1489836
- Bloom, F. E. Training neuroscientists for the 21st-century Trends in Neurosciences 1992 15:383-386 DOI:10.1016/0166-2236(92)90184-a PMID:1279859
- Giovannelli, L., Shiromani, P. J., Jirikowski, G. F., Bloom, F. E. Expression of c-fos protein by immunohistochemically identified oxytocin neurons in the rat hypothalamus upon osmotic stimulation Brain Research 1992 588:41-48 DOI:10.1016/0006-8993(92)91342-c PMID:1393570
- Sanna, P. P., Jirikowski, G. F., Maciejewskilenoir, D., Bloom, F. E. Expression of exogenous vasopressin messenger-rna by magnocellular neurons of the supraoptic and paraventricular nuclei in brattleboro rats Annals of the New York Academy of Sciences 1992 652:462-465 DOI:10.1111/j.1749-6632.1992.tb34385.x PMID:1626850
- Shiromani, P. J., Kilduff, T. S., Bloom, F. E., McCarley, R. W. Cholinergically induced rem-sleep triggers fos-like immunoreactivity in dorsolateral pontine regions associated with rem-sleep Brain Research 1992 580:351-357 DOI:10.1016/0006-8993(92)90968-f PMID:1504815
- Giovannelli, L., Bloom, F. E. C-fos protein expression in the rat subfornical organ following osmotic stimulation Neuroscience Letters 1992 139:1-6 DOI:10.1016/0304-3940(92)90844-w PMID:1407673
- Sanna, P. P., Keyser, K. T., Deerink, T. J., Ellisman, M. H., Karten, H. J., Bloom, F. E. Distribution and ontogeny of parvalbumin immunoreactivity in the chicken retina Neuroscience 1992 47:745-751 DOI:10.1016/0306-4522(92)90182-2 PMID:1584416
- Jirikowski, G. F., Sanna, P. P., Maciejewskilenoir, D., Bloom, F. E. Reversal of diabetes-insipidus in brattleboro rats - intrahypothalamic injection of vasopressin messenger-rna Science 1992 255:996-998 DOI:10.1126/science.1546298 PMID:1546298
- Bloom, F. E., Engel, J. Aberrant genetic expression and opportunities for epilepsy research Epilepsy Research 1992 1-18
- Bloom, F. E. Molecular studies in neuroscience - implications for medicine Biological Chemistry Hoppe-Seyler 1991 372:245-254 PMID:1676270
- Sanna, P. P., Bloom, F. E., Wilson, M. C. Dibutyryl-camp induces snap-25 translocation into the neurites in pc12 Developmental Brain Research 1991 59:104-108 DOI:10.1016/0165-3806(91)90035-h PMID:1645626
- Burton, F. H., Hasel, K. W., Bloom, F. E., Sutcliffe, J. G. Pituitary hyperplasia and gigantism in mice caused by a cholera toxin transgene Nature 1991 350:74-77 DOI:10.1038/350074a0 PMID:1848356
- Sutcliffe, J. G., Travis, G. H., Danielson, P. E., Wong, K. K., Ottiger, H. P., Burton, F. H., Hasel, K. W., Bloom, F. E., Forsspetter, S. Molecular approaches to genes of the cns Epilepsy Research 1991 213-223
- Bloom, F. E., Bulger, R. E., Randolph, M. A. Funding health-sciences research - a strategy to restore balance Clinical Research 1990 38:671-685 PMID:2177388
- Giovannelli, L., Shiromani, P. J., Jirikowski, G. F., Bloom, F. E. Oxytocin neurons in the rat hypothalamus exhibit c-fos immunoreactivity upon osmotic-stress Brain Research 1990 531:299-303 DOI:10.1016/0006-8993(90)90789-e PMID:2126973
- Sanna, P. P., Keyser, K. T., Battenberg, E., Bloom, F. E. Parvalbumin immunoreactivity in the rat retina Neuroscience Letters 1990 118:136-139 DOI:10.1016/0304-3940(90)90267-d PMID:2259462
- Jirikowski, G. F., Sanna, P. P., Bloom, F. E. Messenger-rna coding for oxytocin is present in axons of the hypothalamoneurohypophyseal tract Proceedings of the National Academy of Sciences of the United States of America 1990 87:7400-7404 DOI:10.1073/pnas.87.19.7400 PMID:2268384
- Ottiger, H. P., Battenberg, E. F., Tsou, A. P., Bloom, F. E., Sutcliffe, J. G. 1B1075: a brain- and pituitary-specific mRNA that encodes a novel chromogranin/secretogranin-like component of intracellular vesicles Journal of Neuroscience 1990 10:3135-3147 PMID:2204688
- Watson, J. B., Battenberg, E. F., Wong, K. K., Bloom, F. E., Sutcliffe, J. G. Subtractive cdna cloning of rc3, a rodent cortex-enriched messenger-rna encoding a novel 78 residue protein Journal of Neuroscience Research 1990 26:397-408 DOI:10.1002/jnr.490260402 PMID:2231781
- Polich, J., Ladish, C., Bloom, F. E. P300 assessment of early alzheimers-disease Electroencephalography and Clinical Neurophysiology 1990 77:179-189 DOI:10.1016/0168-5597(90)90036-d PMID:1691970
- Weiss, F., Mitchiner, M., Bloom, F. E., Koob, G. F. Free-choice responding for ethanol versus water in alcohol preferring (p) and unselected wistar rats is differentially modified by naloxone, bromocriptine, and methysergide Psychopharmacology 1990 101:178-186 DOI:10.1007/bf02244123 PMID:2349359
- Sussman, M. A., Battenberg, E., Bloom, F. E., Fowler, V. M. Identification of two nerve growth factor-induced polypeptides in PC12 cells Journal of Molecular Neuroscience 1990 2:163-174 DOI:10.1007/bf02896841 PMID:2275847
- Jirikowski, G. F., Ramalhoortigao, J. F., Kesse, K. W., Bloom, F. E. Insitu hybridization of semithin epon sections with brdu labeled oligonucleotide probes Histochemistry 1990 94:187-190 DOI:10.1007/bf02440186 PMID:2358376
- Oyler, G. A., Higgins, G. A., Hart, R. A., Battenberg, E., Billingsley, M., Bloom, F. E., Wilson, M. C. The identification of a novel synaptosomal-associated protein, snap-25, differentially expressed by neuronal subpopulations Journal of Cell Biology 1989 109:3039-3052 DOI:10.1083/jcb.109.6.3039 PMID:2592413
- Bloom, F. E., Miller, F. D., Ozimek, G. Regulation of neuronal oxytocin messenger-rna by ovarian-steroids in the mature and developing hypothalamus Proceedings of the National Academy of Sciences of the United States of America 1989 86:2468-2472 DOI:10.1073/pnas.86.7.2468 PMID:2928343
- Bloom, F. E., Higgins, G. A., Schmale, H., Wilson, M. C. Cellular-localization of 1b236/myelin-associated glycoprotein messenger-rna during rat-brain development Proceedings of the National Academy of Sciences of the United States of America 1989 86:2074-2078 DOI:10.1073/pnas.86.6.2074 PMID:2467299
- Forsspetter, S., Danielson, P., Battenberg, E., Bloom, F., Sutcliffe, J. G. Nucleotide-sequence and cellular-distribution of rat chromogranin-b (secretogranin-i) messenger-rna in the neuro-endocrine system Journal of Molecular Neuroscience 1989 1:63-75 DOI:10.1007/bf02918892 PMID:2641278
- Koob, G. F., Wall, T. L., Bloom, F. E. Nucleus accumbens as a substrate for the aversive stimulus effects of opiate withdrawal Psychopharmacology 1989 98:530-534 DOI:10.1007/bf00441954 PMID:2505294
- Koob, G. F., Stinus, L., Lemoal, M., Bloom, F. E. Opponent process theory of motivation - neurobiological evidence from studies of opiate dependence Neuroscience and Biobehavioral Reviews 1989 13:135-140 DOI:10.1016/s0149-7634(89)80022-3 PMID:2682399
- Mitler, M. M., Dawson, A., Henriksen, S. J., Sobers, M., Bloom, F. E. Bedtime ethanol increases resistance of upper airways and produces sleep apneas in asymptomatic snorers Alcoholism-Clinical and Experimental Research 1988 12:801-805 DOI:10.1111/j.1530-0277.1988.tb01349.x PMID:3064641
- Koob, G. F., Bloom, F. E. Cellular and molecular mechanisms of drug-dependence Science 1988 242:715-723 DOI:10.1126/science.2903550 PMID:2903550
- Koob, G. F., Mendelson, W. B., Schafer, J., Wall, T. L., Britton, K. T., Bloom, F. E. Picrotoxinin receptor ligand blocks anti-punishment effects of alcohol Alcohol 1988 5:437-443 DOI:10.1016/0741-8329(88)90079-1 PMID:2854473
- Naus, C. C. G., Bloom, F. E. Immunohistochemical analysis of the development of somatostatin in the reeler neocortex Developmental Brain Research 1988 43:61-68 DOI:10.1016/0165-3806(88)90153-8 PMID:2905929
- Delima, A. D., Bloom, F. E., Morrison, J. H. Synaptic organization of serotonin-immunoreactive fibers in primary visual-cortex of the macaque monkey Journal of Comparative Neurology 1988 274:280-294 DOI:10.1002/cne.902740211 PMID:3209742
- Polich, J., Bloom, F. E. Event-related brain potentials in individuals at high and low-risk for developing alcoholism - failure to replicate Alcoholism-Clinical and Experimental Research 1988 12:368-373 DOI:10.1111/j.1530-0277.1988.tb00210.x PMID:3044165
- Naus, C. C. G., Morrison, J. H., Bloom, F. E. Development of somatostatin-containing neurons and fibers in the rat hippocampus Developmental Brain Research 1988 40:113-121 DOI:10.1016/0165-3806(88)90013-2
- Polich, J., Burns, T., Bloom, F. E. P300 and the risk for alcoholism - family history, task-difficulty, and gender Alcoholism-Clinical and Experimental Research 1988 12:248-254 DOI:10.1111/j.1530-0277.1988.tb00189.x PMID:3287988
- Naus, C. C. G., Miller, F. D., Morrison, J. H., Bloom, F. E. Immunohistochemical and insitu hybridization analysis of the development of the rat somatostatin-containing neocortical neuronal system Journal of Comparative Neurology 1988 269:448-463 DOI:10.1002/cne.902690311 PMID:2897381
- Polich, J., Haier, R. J., Buchsbaum, M., Bloom, F. E. Assessment of young men at risk for alcoholism with p300 from a visual-discrimination task Journal of Studies on Alcohol 1988 49:186-190 PMID:3361911
- Bloom, F. E. Neurotransmitters - past, present, and future-directions FASEB Journal 1988 2:32-41 PMID:2891578
- Staunton, D. A., Svensson, T. H., Chouvet, G. E., Siggins, G. R., Bloom, F. E. Systemic phenoxybenzamine but not beta-adrenergic antagonists block noradrenergic inhibition of cerebellar purkinje and hippocampal pyramidal neurons Journal of Neural Transmission 1988 73:101-113 DOI:10.1007/bf01243381 PMID:2905380
- Lipkin, W. I., Battenberg, E. L. F., Bloom, F. E., Oldstone, M. B. A. Viral infection of neurons can depress neurotransmitter mRNA levels without histologic injury Brain Research 1988 451:333-339 DOI:10.1016/0006-8993(88)90779-2 PMID:2908027
- Bloom, F. E., Nave, K. A. A single nucleotide difference in the gene for myelin proteolipid protein defines the jimpy mutation in mouse Journal of Neurochemistry 1987 49:1873-1877 PMID:2445921
- Bloom, F. E., Durand, M., Miller, F. D., Naus, C. C. G. Isotypes of a-tubulin are differentially regulated during neuronal maturation Journal of Cell Biology 1987 105:3065-3073 DOI:10.1083/jcb.105.6.3065 PMID:3693406
- Bloom, F. E., Lai, C., Sutcliffe, J. G., Watson, J. B. Neural protein 1B236/myelin-associated glycoprotein (MAG) defines a subgroup of the immunoglobulin superfamily Immunological Reviews 1987 100:129-151 DOI:10.1111/j.1600-065X.1987.tb00530.x PMID:2450062
- Wiesner, J. B., Henriksen, S. J., Bloom, F. E. Ethanol enhances recurrent inhibition in the dentate gyrus of the hippocampus Neuroscience Letters 1987 79:169-173 DOI:10.1016/0304-3940(87)90691-4 PMID:3670725
- Bloom, F. E., Higgins, G. A., Miller, F. D., Naus, C. C. G. Developmentally regulated rat brain mRNAs: molecular and anatomical characterization Journal of Neuroscience 1987 7:2433-2444 PMID:2441010
- Bloom, F. E., Lai, C., Nave, K. A. Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin Proceedings of the National Academy of Sciences of the United States of America 1987 84:5665-5669 DOI:10.1073/pnas.84.16.5665 PMID:2441390
- Bloom, F. E., Siggins, G. R. Electrophysiological action of ethanol at the cellular-level Alcohol 1987 4:331-337 DOI:10.1016/0741-8329(87)90031-0 PMID:3304331
- Polich, J., Bloom, F. E. P300 from normals and adult children of alcoholics Alcohol 1987 4:301-305 DOI:10.1016/0741-8329(87)90027-9 PMID:3620099
- Travis, G. H., Naus, C. G., Morrison, J. H., Bloom, F. E., Sutcliffe, J. G. Subtractive cloning of complementary dnas and analysis of messenger-rnas with regional heterogeneous distributions in primate cortex Neuropharmacology 1987 26:845-854 DOI:10.1016/0028-3908(87)90061-x PMID:2443867
- McKinnon, R. D., Danielson, P., Brow, M. A. D., Bloom, F. E., Sutcliffe, J. G. Expression of small cytoplasmic transcripts of the rat identifier element in vivo and in cultured cells Molecular and Cellular Biology 1987 7:2148-2154 PMID:2439903 PMCID:PMC365337
- Siggins, G. R., Bloom, F. E., French, E. D., Madamba, S. G., Mancillas, J., Pittman, Q. J., Rogers, J. Electrophysiology of ethanol on central neurons Annals of the New York Academy of Sciences 1987 492:350-366 DOI:10.1111/j.1749-6632.1987.tb48692.x PMID:3474932
- Lebrun, C., Lemoal, M., Dantzer, R., Bloom, F. E., Koob, G. F. Hypertonic saline mimics the effects of vasopressin on inhibitory avoidance in the rat Behavioral and Neural Biology 1987 47:130-137 DOI:10.1016/s0163-1047(87)90229-9 PMID:3579833
- Bloom, F. E., Sutcliffe, J. G. Brain-specific genes - strategies and issues Current Topics in Developmental Biology 1987 21:117-150 PMID:2443305
- Lewis, D. A., Bloom, F. E. Clinical perspectives on neuropeptides Annual Review of Medicine 1987 38:143-148 DOI:10.1146/annurev.med.38.1.143 PMID:2953298
- Bloom, F. E. Hypothalamus: past, present, future Advances in Biochemical Psychopharmacology 1987 43:1-11 PMID:2884815
- Bloom, F. E. Molecular diversity and cellular functions of neuropeptides Progress in Brain Research 1987 72:213-220 PMID:3039577
- Bloom, F. E., Brow, M. A., Lai, C., Nave, K. A., Noronha, A. B., Quarles, R. H., Sutcliffe, J. G. Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing Proceedings of the National Academy of Sciences of the United States of America 1987 84:4337-4341 DOI:10.1073/pnas.84.12.4337 PMID:2438699 PMCID:PMC305080
- Wiesner, J. B., Henriksen, S. J., Bloom, F. E. Opioid enhancement of perforant path transmission - effect of an enkephalin analog on inhibition and facilitation in the dentate gyrus Brain Research 1986 399:404-408 DOI:10.1016/0006-8993(86)91537-4 PMID:3030491
- Celio, M. R., Scharer, L., Morrison, J. H., Norman, A. W., Bloom, F. E. Calbindin immunoreactivity alternates with cytochrome-c-oxidase-rich zones in some layers of the primate visual-cortex Nature 1986 323:715-717 DOI:10.1038/323715a0 PMID:3022149
- Mancillas, J. R., Siggins, G. R., Bloom, F. E. Somatostatin selectively enhances acetylcholine-induced excitations in rat hippocampus and cortex Proceedings of the National Academy of Sciences of the United States of America 1986 83:7518-7521 DOI:10.1073/pnas.83.19.7518 PMID:2876428
- Loughlin, S. E., Foote, S. L., Bloom, F. E. Efferent projections of nucleus locus-coeruleus - topographic organization of cells of origin demonstrated by 3-dimensional reconstruction Neuroscience 1986 18:291-306 DOI:10.1016/0306-4522(86)90155-7 PMID:3736860
- Celio, M. R., Keller, G. A., Bloom, F. E. Immunoelectronmicroscopy of neural antigens on ultrathin frozen-sections Journal of Histochemistry & Cytochemistry 1986 34:491-500 PMID:3512699
- Koob, G. F., Dantzer, R., Bluthe, R. M., Lebrun, C., Bloom, F. E., Lemoal, M. Central injections of arginine vasopressin prolong extinction of active-avoidance Peptides 1986 7:213-218 DOI:10.1016/0196-9781(86)90215-9 PMID:3737445
- Polich, J., Ehlers, C. L., Otis, S., Mandell, A. J., Bloom, F. E. P300 latency reflects the degree of cognitive decline in dementing illness Electroencephalography and Clinical Neurophysiology 1986 63:138-144 DOI:10.1016/0013-4694(86)90007-6 PMID:2417814
- Battenberg, E., Bloom, F. E., Kiel, M., Lenoir, D. The brain-specific gene 1B236 is expressed postnatally in the developing rat brain Journal of Neuroscience 1986 6:522-530 PMID:3950709
- Mancillas, J. R., Siggins, G. R., Bloom, F. E. Systemic ethanol: selective enhancement of responses to acetylcholine and somatostatin in hippocampus Science 1986 231:161-163 DOI:10.1126/science.2867600 PMID:2867600
- Bloom, F. E. Genetic background for multiple messengers Progress in Brain Research 1986 68:149-159 DOI:10.1016/s0079-6123(08)60236-8 PMID:3562850
- Bloom, F. E. Identifying neuropeptides by gene cloning Psychopharmacology Bulletin 1986 22:701-707 PMID:3797575
- Bloom, F. E., Lai, C., Nave, K. A. Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing Proceedings of the National Academy of Sciences of the United States of America 1986 83:9264-9268 DOI:10.1073/pnas.83.23.9264 PMID:3466187
- Bloom, F. E. Molecular mechanisms of psychopathology Clinical Neuropharmacology 1986 9:1-2
- Chavkin, C., Bloom, F. E. Opiate antagonists do not alter neuronal responses to stimulation of opioid-containing pathways in rat hippocampus Neuropeptides 1986 7:19-22 DOI:10.1016/0143-4179(86)90074-0 PMID:2869440
- Polich, J., Bloom, F. E. P300 and alcohol-consumption in normals and individuals at risk for alcoholism - a preliminary-report Progress in Neuro-Psychopharmacology & Biological Psychiatry 1986 10:201-210 DOI:10.1016/0278-5846(86)90074-6 PMID:3749511
- Deyo, S. N., Shoemaker, W. J., Ettenberg, A., Bloom, F. E., Koob, G. F. Subcutaneous administration of behaviorally effective doses of arginine vasopressin change brain avp content only in median-eminence Neuroendocrinology 1986 42:260-266 DOI:10.1159/000124449 PMID:3951675
- Ferron, A., Siggins, G. R., Bloom, F. E. Vasoactive intestinal polypeptide acts synergistically with norepinephrine to depress spontaneous discharge rate in cerebral cortical-neurons Proceedings of the National Academy of Sciences of the United States of America 1985 82:8810-8812 DOI:10.1073/pnas.82.24.8810 PMID:3866254
- Koob, G. F., Lebrun, C., Martinez, J. L., Dantzer, R., Lemoal, M., Bloom, F. E. Arginine vasopressin, stress, and memory Annals of the New York Academy of Sciences 1985 444:194-202 DOI:10.1111/j.1749-6632.1985.tb37589.x PMID:3860087
- Vaccarino, F. J., Bloom, F. E., Koob, G. F. Blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat Psychopharmacology 1985 86:37-42 DOI:10.1007/bf00431681 PMID:2991967
- Bakhit, C., Bloom, F. E., Malfroy, B., Sutcliffe, J. G. Brain-specific polypeptide 1B236 exists in multiple molecular forms Proceedings of the National Academy of Sciences of the United States of America 1985 82:2009-2013 DOI:10.1073/pnas.82.7.2009 PMID:3856879
- Chavkin, C., Shoemaker, W. J., McGinty, J. F., Bayon, A., Bloom, F. E. Characterization of the prodynorphin and proenkephalin neuropeptide systems in rat hippocampus Journal of Neuroscience 1985 5:808-816 PMID:3838345
- Koob, G. F., Bloom, F. E. Corticotropin-releasing factor and behavior Federation Proceedings 1985 44:259-263 PMID:3871412
- Vaccarino, F. J., Pettit, H. O., Bloom, F. E., Koob, G. F. Effects of intracerebroventricular administration of methyl naloxonium chloride on heroin self-administration in the rat Pharmacology, Biochemistry and Behavior 1985 23:495-498 DOI:10.1016/0091-3057(85)90027-9
- Battenberg, E. L. F., Bloom, F. E., Sutcliffe, J. G. Immunocytochemical mapping of 1B236, a brain-specific neuronal polypeptide deduced from the sequence of a cloned mRNA Journal of Neuroscience 1985 5:1781-1802 PMID:4020419
- Bloom, F. E. Neuropeptides and other mediators in the central nervous-system Journal of Immunology 1985 135:S743-S745
- Bloom, F. E. Neurotransmitter diversity and its functional-significance Journal of the Royal Society of Medicine 1985 78:189-192 PMID:2857791 PMCID:PMC1289631
- Koob, G. F., Dantzer, R., Rodriguez, F., Bloom, F. E., Lemoal, M. Osmotic-stress mimics effects of vasopressin on learned behavior Nature 1985 315:750-752 DOI:10.1038/315750a0 PMID:4010780
- Chavkin, C., Henriksen, S. J., Siggins, G. R., Bloom, F. E. Selective inactivation of opioid receptors in rat hippocampus demonstrates that dynorphin-a and dynorphin-b may act on mu-receptors in the ca1 region Brain Research 1985 331:366-370 DOI:10.1016/0006-8993(85)91565-3 PMID:2859095
- Morrison, J. H., Rogers, J., Scherr, S., Benoit, R., Bloom, F. E. Somatostatin immunoreactivity in neuritic plaques of alzheimers patients Nature 1985 314:90-92 DOI:10.1038/314090a0 PMID:2858056
- Benoit, R., Bohlen, P., Ling, N., Esch, F., Baird, A., Ying, S. Y., Wehrenberg, W. B., Guillemin, R., Morrison, J. H., Bakhit, C., Koda, L., Bloom, F. E. Somatostatin-28 1-12 - like peptides Advances in Experimental Medicine and Biology 1985 188:89-107 PMID:2863951
- Vaccarino, F. J., Bloom, F. E., Rivier, J., Vale, W., Koob, G. F. Stimulation of food-intake in rats by centrally administered hypothalamic growth hormone-releasing factor Nature 1985 314:167-168 DOI:10.1038/314167a0 PMID:3919314
- Lebrun, C., Lemoal, M., Koob, G. F., Bloom, F. E. Vasopressin pressor antagonist injected centrally reverses behavioral-effects of peripheral injection of vasopressin, but only at doses that reverse increase in blood-pressure Regulatory Peptides 1985 11:173-181 DOI:10.1016/0167-0115(85)90077-1 PMID:4035008
- Way, W. L., Hosobuchi, Y., Johnson, B. H., Eger, E. I., Bloom, F. E. Anesthesia does not increase opioid peptides in cerebrospinal fluid of humans Anesthesiology 1984 60:43-45 DOI:10.1097/00000542-198401000-00009 PMID:6318607
- Lebrun, C. J., Rigter, H., Martinez, J. L., Koob, G. F., Lemoal, M., Bloom, F. E. Antagonism of effects of vasopressin (avp) on inhibitory avoidance by a vasopressin antagonist peptide dptyr(me)avp Life Sciences 1984 35:1505-1512 DOI:10.1016/0024-3205(84)90168-1 PMID:6482669
- Lemoal, M., Dantzer, R., Mormede, P., Baduel, A., Lebrun, C., Ettenberg, A., Vanderkooy, D., Wenger, J., Deyo, S., Koob, G. F., Bloom, F. E. Behavioral-effects of peripheral administration of arginine vasopressin - a review of our search for a mode of action and a hypothesis Psychoneuroendocrinology 1984 9:319-341 DOI:10.1016/0306-4530(84)90042-8 PMID:6514931
- Bloom, F. E., Lai, C., Lerner, R. A., Sutcliffe, J. G. Brain-specific genes have identifier sequences in their introns Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1984 81:713-717 DOI:10.1073/pnas.81.3.713 PMID:6583673
- Pettit, H. O., Ettenberg, A., Bloom, F. E., Koob, G. F. Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats Psychopharmacology 1984 84:167-173 DOI:10.1007/bf00427441 PMID:6438676
- Koob, G. F., Thatcherbritton, K., Britton, D. R., Roberts, D. C. S., Bloom, F. E. Destruction of the locus coeruleus or the dorsal ne bundle does not alter the release of punished responding by ethanol and chlordiazepoxide Physiology & Behavior 1984 33:479-485 DOI:10.1016/0031-9384(84)90172-0 PMID:6542682
- Baird, A., Bloch, B., Bloom, F. E., Bohlen, P., Gubler, U., Leguellec, D., Reymond, C. Detection of the messenger RNA coding for preproenkephalin A in bovine adrenal by in situ hybridization Regulatory Peptides 1984 8:345-354 DOI:10.1016/0167-0115(84)90045-4 PMID:6548571
- Britton, K. T., Svensson, T., Schwartz, J., Bloom, F. E., Koob, G. F. Dorsal noradrenergic bundle lesions fail to alter opiate withdrawal or suppression of opiate withdrawal by clonidine Life Sciences 1984 34:133-139 DOI:10.1016/0024-3205(84)90583-6 PMID:6537983
- Koob, G. F., Pettit, H. O., Ettenberg, A., Bloom, F. E. Effects of opiate antagonists and their quaternary derivatives on heroin self-administration in the rat Journal of Pharmacology and Experimental Therapeutics 1984 229:481-486 PMID:6716270
- Bloom, F. E. Endorphins and psychiatry - pre-clinical perspectives Psychiatric Developments 1984 2:1-21 PMID:6326090
- Bakhit, C., Koda, L., Benoit, R., Morrison, J. H., Bloom, F. E. Evidence for selective release of somatostatin-14 and somatostatin-28(1-12) from rat hypothalamus Journal of Neuroscience 1984 4:411-419 PMID:6142098
- Koda, L. Y., Madamba, S. G., Bloom, F. E. Hypotensive response of ethanol in rats pretreated with disulfiram or nitrefazole Life Sciences 1984 35:1659-1665 DOI:10.1016/0024-3205(84)90177-2 PMID:6482674
- Magistretti, P. J., Morrison, J. H., Shoemaker, W. J., Bloom, F. E. Morphological and functional correlates of vip neurons in cerebral-cortex Peptides 1984 5:213-218 DOI:10.1016/0196-9781(84)90209-2 PMID:6473153
- Bloom, F. E. Neurotransmitter molecular diversity: some views of its functional significance Biomedical Research-Tokyo 1984 5:49-56
- Rogers, J., Zornetzer, S. F., Bloom, F. E., Mervis, R. E. Senescent microstructural changes in rat cerebellum Brain Research 1984 292:23-32 DOI:10.1016/0006-8993(84)90886-2 PMID:6199084
- Morrison, J. H., Magistretti, P. J., Benoit, R., Bloom, F. E. The distribution and morphological-characteristics of the intracortical vip-positive cell - an immunohistochemical analysis Brain Research 1984 292:269-282 DOI:10.1016/0006-8993(84)90763-7 PMID:6362778
- McGinty, J. F., Vanderkooy, D., Bloom, F. E. The distribution and morphology of opioid peptide immunoreactive neurons in the cerebral-cortex of rats Journal of Neuroscience 1984 4:1104-1117 PMID:6143786
- Bloom, F. E. The functional-significance of neurotransmitter diversity American Journal of Physiology 1984 246:C184-C194 PMID:6142651
- Vanderkooy, D., Koda, L. Y., McGinty, J. F., Gerfen, C. R., Bloom, F. E. The organization of projections from the cortex, amygdala, and hypothalamus to the nucleus of the solitary tract in rat Journal of Comparative Neurology 1984 224:1-24 DOI:10.1002/cne.902240102 PMID:6715573
- McGinty, J. F., Koda, L. Y., Bloom, F. E. A combined vascular catecholamine fluorescence method reveals the relative vascularity of rat locus coeruleus and the paraventricular and supraoptic nuclei of the hypothalamus Neuroscience Letters 1983 36:117-123 DOI:10.1016/0304-3940(83)90252-5 PMID:6866325
- Gozes, I., O'Connor, D. T., Bloom, F. E. A possible high molecular-weight precursor to vasoactive intestinal polypeptide sequestered into pheochromocytoma chromaffin granules Regulatory Peptides 1983 6:111-119 DOI:10.1016/0167-0115(83)90004-6 PMID:6878752
- Schwartz, J. M., Ehlers, C. L., Detmer, W. M., Bloom, F. E. Amygdala kindling after ligation of the middle cerebral-artery in the rat Experimental Neurology 1983 80:484-490 DOI:10.1016/0014-4886(83)90300-x PMID:6840252
- Ehlers, C. L., Russo, P. V., Mandell, A. J., Bloom, F. E. Architecture of rat nocturnal locomotion - a predictive descriptor of the effects of anti-depressant and antimanic treatments Psychopharmacology Bulletin 1983 19:692-695
- Koob, G. F., Bloom, F. E. Behavioral effects of opioid peptides British Medical Bulletin 1983 39:89-94 PMID:6340789
- Ettenberg, A., Vanderkooy, D., Lemoal, M., Koob, G. F., Bloom, F. E. Can aversive properties of (peripherally-injected) vasopressin account for its putative role in memory Behavioural Brain Research 1983 7:331-350 DOI:10.1016/0166-4328(83)90024-4 PMID:6838716
- Bloom, F. E., Sutcliffe, J. G. Cellular-localization and function of the proteins encoded by brain-specific messenger-RNAs Cold Spring Harbor Symposia on Quantitative Biology 1983 48:477-484 PMID:6586369
- Vale, W., Rivier, C., Brown, M. R., Spiess, J., Koob, G., Swanson, L., Bilezikjian, L., Bloom, F., Rivier, J. Chemical and biological characterization of corticotropin releasing-factor Recent Progress in Hormone Research 1983 39:245-270 PMID:6314446
- Bloom, F. E., Baetge, G., Deyo, S., Ettenberg, A., Koda, L., Magistretti, P. J., Shoemaker, W. J., Staunton, D. A. Chemical and physiological-aspects of the actions of lithium and anti-depressant drugs Neuropharmacology 1983 22:359-365 DOI:10.1016/0028-3908(83)90184-3
- Bloom, F. E. Chemical communication in the cns - neurotransmitters and their function Progress in Brain Research 1983 58:3-9 DOI:10.1016/s0079-6123(08)60001-1 PMID:6138811
- Ehlers, C. L., Henriksen, S. J., Wang, M., Rivier, J., Vale, W., Bloom, F. E. Corticotropin releasing-factor produces increases in brain excitability and convulsive seizures in rats Brain Research 1983 278:332-336 DOI:10.1016/0006-8993(83)90266-4 PMID:6605787
- Koda, L. Y., Bloom, F. E. Distribution of catecholamine-containing cell-bodies and blood-vessels in the rat nucleus tractus solitarius Brain Research 1983 289:71-78 DOI:10.1016/0006-8993(83)90007-0 PMID:6661657
- McGinty, J. F., Bloom, F. E. Double immunostaining reveals distinctions among opioid peptidergic neurons in the medial basal hypothalamus Brain Research 1983 278:145-153 DOI:10.1016/0006-8993(83)90233-0 PMID:6196087
- McGinty, J. F., Henriksen, S. J., Goldstein, A., Terenius, L., Bloom, F. E. Dynorphin is contained within hippocampal mossy fibers: immunochemical alterations after kainic acid administration and colchicine-induced neurotoxicity Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1983 80:589-593 DOI:10.1073/pnas.80.2.589 PMID:6132379 PMCID:PMC393425
- Magistretti, P. J., Morrison, J. H., Shoemaker, W. J., Bloom, F. E. Effect of 6-hydroxydopamine lesions on norepinephrine-induced h-3 -labeled glycogen hydrolysis in mouse cortical slices Brain Research 1983 261:159-162 DOI:10.1016/0006-8993(83)91297-0 PMID:6301624
- Bakhit, C., Benoit, R., Bloom, F. E. Effects of cysteamine on pro-somatostatin related peptides Regulatory Peptides 1983 6:169-177 DOI:10.1016/0167-0115(83)90010-1 PMID:6192467
- Chavkin, C., Bakhit, C., Bloom, F. E. Evidence for dynorphin-a as a neurotransmitter in rat hippocampus Life Sciences 1983 33:13-16 DOI:10.1016/0024-3205(83)90432-0 PMID:6141483
- Magistretti, P. J., Manthorpe, M., Bloom, F. E., Varon, S. Functional receptors for vasoactive intestinal polypeptide in cultured astroglia from neonatal rat-brain Regulatory Peptides 1983 6:71-80 DOI:10.1016/0167-0115(83)90136-2 PMID:6306734
- Bloom, F. E., Shinnick, T. M., Sutcliffe, J. G. Identifying the protein products of brain-specific genes with antibodies to chemically synthesized peptides Cell 1983 33:671-682 DOI:10.1016/0092-8674(83)90010-7 PMID:6347394
- Bloom, F. E., Battenberg, E. L. F. Immunocytochemistry of endorphins and enkephalins Methods in Enzymology 1983 103:670-687 DOI:10.1016/S0076-6879(83)03048-7 PMID:6321899
- Morrison, J. H., Benoit, R., Magistretti, P. J., Bloom, F. E. Immunohistochemical distribution of pro-somatostatin-related peptides in cerebral-cortex Brain Research 1983 262:344-351 DOI:10.1016/0006-8993(83)91031-4 PMID:6132664
- Iversen, L. L., Rossor, M. N., Reynolds, G. P., Hills, R., Roth, M., Mountjoy, C. Q., Foote, S. L., Morrison, J. H., Bloom, F. E. Loss of pigmented dopamine-beta-hydroxylase positive cells from locus coeruleus in senile dementia of alzheimer type Neuroscience Letters 1983 39:95-100 DOI:10.1016/0304-3940(83)90171-4 PMID:6633940
- Shier, W. T., Koda, L. Y., Bloom, F. E. Metabolism of h-3 dopamine following intracerebroventricular injection in rats pretreated with ethanol or chloral hydrate Neuropharmacology 1983 22:279-286 DOI:10.1016/0028-3908(83)90241-1 PMID:6843789
- Battenberg, E. L. F., Bloom, F. E., Gozes, I., Johnson, E., Katz, D. H., Liu, F. T. Monoclonal antibodies against vasoactive intestinal polypeptide: Studies of structure and related antigens Journal of Neurochemistry 1983 41:549-555 DOI:10.1111/j.1471-4159.1983.tb04774.x PMID:6875552
- Arnsten, A. F. T., Segal, D. S., Neville, H. J., Hillyard, S. A., Janowsky, D. S., Judd, L. L., Bloom, F. E. Naloxone augments electro-physiological signs of selective attention in man Nature 1983 304:725-727 DOI:10.1038/304725a0 PMID:6888538
- Atkinson, J. H., Jr., Kremer, E. F., Risch, S. C., Bloom, F. E. Neuroendocrine function and endogenous opioid peptide systems in chronic pain Psychosomatics 1983 24:899-901, 905, 909 passim DOI:10.1016/S0033-3182(83)73141-5 PMID:6316397
- Foote, S. L., Bloom, F. E., Astonjones, G. Nucleus locus ceruleus - new evidence of anatomical and physiological specificity Physiological Reviews 1983 63:844-914 PMID:6308694
- Atkinson, J. H., Kremer, E. F., Risch, S. C., Morgan, C. D., Azad, R. F., Ehlers, C. L., Bloom, F. E. Plasma measures of beta-endorphin beta-lipotropin-like immunoreactivity in chronic pain syndrome and psychiatric subjects Psychiatry Research 1983 9:319-327 DOI:10.1016/0165-1781(83)90005-7 PMID:6316390
- Chavkin, C., Bakhit, C., Weber, E., Bloom, F. E. Relative contents and concomitant release of prodynorphin neoendorphin-derived peptides in rat hippocampus Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1983 80:7669-7673 DOI:10.1073/pnas.80.24.7669 PMID:6143317
- Bakhit, C., Benoit, R., Bloom, F. E. Release of somatostatin-28(1-12) from rat hypothalamus in vitro Nature 1983 301:524-526 DOI:10.1038/301524a0 PMID:6130476
- Benabid, A. L., Henriksen, S. J., McGinty, J. F., Bloom, F. E. Thalamic nucleus ventro-postero-lateralis inhibits nucleus parafascicularis response to noxious stimuli through a non-opioid pathway Brain Research 1983 280:217-231 DOI:10.1016/0006-8993(83)90052-5 PMID:6652483
- Ehlers, C. L., Indik, J. H., Koob, G. F., Bloom, F. E. The effect of single and repeated electroconvulsive shock (ECS) on locomotor-activity in rats Progress in Neuro-Psychopharmacology & Biological Psychiatry 1983 7:217-222 DOI:10.1016/0278-5846(83)90110-0 PMID:6684316
- Bloom, F. E. The endorphins - a growing family of pharmacologically pertinent peptides Annual Review of Pharmacology and Toxicology 1983 23:151-170 DOI:10.1146/annurev.pa.23.040183.001055 PMID:6307119
- Ettenberg, A., Koob, G. F., Bloom, F. E. Time course of alpha-flupenthixol action explains response artifacts of neuroleptic action on brain-stimulation reward - reply Science 1983 222:1253-1254 DOI:10.1126/science.222.4629.1253-a
- Ettenberg, A., Lemoal, M., Koob, G. F., Bloom, F. E. Vasopressin potentiation in the performance of a learned appetitive task - reversal by a pressor antagonist analog of vasopressin Pharmacology, Biochemistry and Behavior 1983 18:645-647 DOI:10.1016/0091-3057(83)90294-0 PMID:6867069
- Pittman, Q. J., Rogers, J., Bloom, F. E. Arginine vasopressin deficient brattleboro rats fail to develop tolerance to the hypothermic effects of ethanol Regulatory Peptides 1982 4:33-41 DOI:10.1016/0167-0115(82)90106-9 PMID:6289383
- Koob, G. F., Bloom, F. E. Behavioral-effects of neuropeptides - endorphins and vasopressin Annual Review of Physiology 1982 44:571-582 DOI:10.1146/annurev.ph.44.030182.003035 PMID:7041806
- Schwartz, J. M., Ksir, C., Koob, G. F., Bloom, F. E. Changes in locomotor response to beta-endorphin microinfusion during and after opiate abstinence syndrome - a proposal for a model of the onset of mania Psychiatry Research 1982 7:153-161 DOI:10.1016/0165-1781(92)90088-k PMID:6292980
- Bloom, F. E., Koda, L. Y. Chemical circuitry and central cardiovascular regulation Clinical and Experimental Hypertension 1982 4:529-541 DOI:10.3109/10641968209061597 PMID:6125281
- Bloom, F. E., Lerner, R. A., Sutcliffe, J. G. Common 82-nucleotide sequence unique to brain-RNA Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1982 79:4942-4946 DOI:10.1073/pnas.79.16.4942 PMID:6956902
- Bloom, F. E., Battenberg, E. L. F., Rivier, J., Vale, W. Corticotropin releasing-factor (crf) - immunoreactive neurons and fibers in rat hypothalamus Regulatory Peptides 1982 4:43-48 DOI:10.1016/0167-0115(82)90107-0 PMID:6750704
- Pittman, Q. J., Rogers, J., Bloom, F. E. Deficits in tolerance to ethanol in brattleboro rats Annals of the New York Academy of Sciences 1982 394:764-766 DOI:10.1111/j.1749-6632.1982.tb37496.x PMID:6960795
- Staunton, D. A., Magistretti, P. J., Koob, G. F., Shoemaker, W. J., Bloom, F. E. Dopaminergic super-sensitivity induced by denervation and chronic receptor blockade is additive Nature 1982 299:72-74 DOI:10.1038/299072a0 PMID:7110328
- Staunton, D. A., Deyo, S. N., Shoemaker, W. J., Ettenberg, A., Bloom, F. E. Effects of chronic lithium on enkephalin systems and pain responsiveness Life Sciences 1982 31:1837-1840 DOI:10.1016/0024-3205(82)90223-5 PMID:7154836
- Staunton, D. A., Magistretti, P. J., Shoemaker, W. J., Bloom, F. E. Effects of chronic lithium treatment on dopamine-receptors in the rat corpus striatum .1. Locomotor-activity and behavioral super-sensitivity Brain Research 1982 232:391-400 DOI:10.1016/0006-8993(82)90282-7 PMID:6322914
- Staunton, D. A., Magistretti, P. J., Shoemaker, W. J., Deyo, S. N., Bloom, F. E. Effects of chronic lithium treatment on dopamine-receptors in the rat corpus striatum .2. No effect on denervation or neuroleptic-induced super-sensitivity Brain Research 1982 232:401-412 DOI:10.1016/0006-8993(82)90283-9 PMID:6322915
- Schultz, J. E., Siggins, G. R., Turck, M., Bloom, F. E. Electrophysiological and biochemical comparison of the acute and chronic effects of lithium and tricyclic antidepressants Advances in Biochemical Psychopharmacology 1982 31:347-357 PMID:6282062
- Berger, T., French, E. D., Siggins, G. R., Shier, W. T., Bloom, F. E. Ethanol and some tetrahydroisoquinolines alter the discharge of cortical and hippocampal-neurons - relationship to endogenous opioids Pharmacology, Biochemistry and Behavior 1982 17:813-821 DOI:10.1016/0091-3057(82)90365-3 PMID:7178189
- Ettenberg, A., Pettit, H. O., Bloom, F. E., Koob, G. F. Heroin and cocaine intravenous self-administration in rats - mediation by separate neural systems Psychopharmacology 1982 78:204-209 DOI:10.1007/bf00428151 PMID:6296898
- Morrison, J. H., Benoit, R., Magistretti, P. J., Ling, N., Bloom, F. E. Immunohistochemical distribution of pro-somatostatin-related peptides in hippocampus Neuroscience Letters 1982 34:137-142 DOI:10.1016/0304-3940(82)90165-3 PMID:6135179
- Henriksen, S. J., Chouvet, G., Bloom, F. E. In vivo cellular responses to electrophoretically applied dynorphin in the rat hippocampus Life Sciences 1982 31:1785-1788 DOI:10.1016/0024-3205(82)90210-7 PMID:6130440
- Morrison, J. H., Foote, S. L., Oconnor, D., Bloom, F. E. Laminar, tangential and regional organization of the noradrenergic innervation of monkey cortex: dopamine-beta-hydroxylase immunohistochemistry Brain Research Bulletin 1982 9:309-319 DOI:10.1016/0361-9230(82)90144-7 PMID:6756551
- Astonjones, G., Foote, S. L., Bloom, F. E. Low-doses of ethanol disrupt sensory responses of brain noradrenergic neurons Nature 1982 296:857-860 DOI:10.1038/296857a0 PMID:6280069
- Bloom, F. E. Neurotransmitters and cns disease - the future Lancet 1982 2:1381-1384 PMID:6129472
- Bloom, F. E. New frontiers in molecular neuroscience Trends in Neurosciences 1982 5:295-296 DOI:10.1016/0166-2236(82)90184-9
- Morrison, J. H., Foote, S. L., Molliver, M. E., Bloom, F. E., Lidov, H. G. W. Noradrenergic and serotonergic fibers innervate complementary layers in monkey primary visual-cortex - an immunohistochemical study Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1982 79:2401-2405 DOI:10.1073/pnas.79.7.2401 PMID:7048320
- McGinty, J. F., Henriksen, S. J., Goldstein, A., Terenius, L., Bloom, F. E. Opioid peptide identity and localization in hippocampus Life Sciences 1982 31:1797-1800 DOI:10.1016/0024-3205(82)90213-2 PMID:6759828
- Henriksen, S. J., Chouvet, G., McGinty, J., Bloom, F. E. Opioid-peptides in the hippocampus - anatomical and physiological considerations Annals of the New York Academy of Sciences 1982 398:207-219 DOI:10.1111/j.1749-6632.1982.tb39495.x PMID:6130736
- Ehlers, C. L., Koob, G. F., Bloom, F. E. Post-ictal locomotor-activity in 3 different rat models of epilepsy Brain Research 1982 250:178-182 DOI:10.1016/0006-8993(82)90966-0 PMID:7139314
- Vanderkooy, D., McGinty, J. F., Koda, L. Y., Gerfen, C. R., Bloom, F. E. Visceral cortex - a direct connection from prefrontal cortex to the solitary nucleus in rat Neuroscience Letters 1982 33:123-127 DOI:10.1016/0304-3940(82)90238-5 PMID:6185887
- Bloom, F. E., Feldman, J. D., Gilman, S. C., Schwartz, J. M. β-endorphin enhances lymphocyte proliferative responses Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1982 79:4226-4230 DOI:10.1073/pnas.79.13.4226 PMID:6287475
- Astonjones, G., Bloom, F. E. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle Journal of Neuroscience 1981 1:876-886 PMID:7346592
- Roberts, D. C. S., Bloom, F. E. Adrenal steroid-induced changes in beta-adrenergic-receptor binding in rat hippocampus European Journal of Pharmacology 1981 74:37-41 DOI:10.1016/0014-2999(81)90320-4 PMID:6274649
- Koob, G. F., Lemoal, M., Gaffori, O., Manning, M., Sawyer, W. H., Rivier, J., Bloom, F. E. Arginine vasopressin and a vasopressin antagonist peptide - opposite effects on extinction of active-avoidance in rats Regulatory Peptides 1981 2:153-163 DOI:10.1016/0167-0115(81)90009-4 PMID:7255768
- Schultz, J. E., Siggins, G. R., Schocker, F. W., Turck, M., Bloom, F. E. Effects of prolonged treatment with lithium and tricyclic anti-depressants on discharge frequency, norepinephrine responses and beta-receptor binding in rat cerebellum - electro-physiological and biochemical-comparison Journal of Pharmacology and Experimental Therapeutics 1981 216:28-38 PMID:6256526
- Bloom, F. E., Siggins, G. R., Henriksen, S. J. Electrophysiologic assessment of receptor changes following chronic drug treatment Federation Proceedings 1981 40:166-172 PMID:6257556
- Ettenberg, A., Rogers, J., Koob, G. F., Bloom, F. E. Endogenous opiates and fasting Science 1981 213:1282-1282 DOI:10.1126/science.6267697 PMID:6267697
- Newlin, S. A., Mancillastrevino, J., Bloom, F. E. Ethanol causes increases in excitation and inhibition in area ca3 of the dorsal hippocampus Brain Research 1981 209:113-128 DOI:10.1016/0006-8993(81)91175-6 PMID:6260298
- Schulman, J. A., Bloom, F. E. Golgi cells of the cerebellum are inhibited by inferior olive activity Brain Research 1981 210:350-355 DOI:10.1016/0006-8993(81)90908-2 PMID:7225813
- Mancillas, J. R., McGinty, J. F., Selverston, A. I., Karten, H., Bloom, F. E. Immuno-cytochemical localization of enkephalin and substance-p in retina and eyestalk neurons of lobster Nature 1981 293:576-578 DOI:10.1038/293576a0 PMID:6169995
- Bayon, A., Shoemaker, W. J., Lugo, L., Azad, R., Ling, N., Druckercolin, R. R., Bloom, F. E. In vivo release of enkephalin from the globus pallidus Neuroscience Letters 1981 24:65-70 DOI:10.1016/0304-3940(81)90360-8 PMID:7266940
- Wiener, S. G., Shoemaker, W. J., Koda, L. Y., Bloom, F. E. Interaction of ethanol and nutrition during gestation - influence on maternal and offspring development in the rat Journal of Pharmacology and Experimental Therapeutics 1981 216:572-579 PMID:7205638
- Ehlers, C. L., Henriksen, S. J., Bloom, F. E. Levonantradol potentiates the anticonvulsant effects of diazepam and valproic acid in the kindling model of epilepsy Journal of Clinical Pharmacology 1981 21:S406-S412
- Koda, L. Y., Shoemaker, W. J., Baetge, G., Bloom, F. E. Lithium treatment decreases blood-pressure in genetically hypertensive rats European Journal of Pharmacology 1981 76:411-415 DOI:10.1016/0014-2999(81)90112-6 PMID:7327210
- Bloom, F. E. Neuropeptides Scientific American 1981 245:148-168 PMID:6117125
- Astonjones, G., Bloom, F. E. Norepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli Journal of Neuroscience 1981 1:887-900 PMID:7346593
- Ettenberg, A., Koob, G. F., Bloom, F. E. Response artifact in the measurement of neuroleptic-induced anhedonia Science 1981 213:357-359 DOI:10.1126/science.7244622 PMID:7244622
- Rogers, J., Zornetzer, S. F., Bloom, F. E. Senescent pathology of cerebellum - purkinje neurons and their parallel fiber afferents Neurobiology of Aging 1981 2:15-25 DOI:10.1016/0197-4580(81)90054-3 PMID:6267492
- Pittman, Q. J., Hatton, J. D., Bloom, F. E. Spontaneous activity in perfused hypothalamic slices - dependence on calcium content of perfusate Experimental Brain Research 1981 42:49-52 PMID:7215509
- Joyce, E. M., Koob, G. F., Strecker, R., Iversen, S. D., Bloom, F. E. The behavioral-effects of enkephalin analogs injected into the ventral tegmental area and globus pallidus Brain Research 1981 221:359-370 DOI:10.1016/0006-8993(81)90784-8 PMID:7025963
- Magistretti, P. J., Morrison, J. H., Shoemaker, W. J., Sapin, V., Bloom, F. E. Vasoactive intestinal polypeptide induces glycogenolysis in mouse cortical slices - a possible regulatory mechanism for the local-control of energy-metabolism Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1981 78:6535-6539 DOI:10.1073/pnas.78.10.6535 PMID:6118864
- Lemoal, M., Koob, G. F., Koda, L. Y., Bloom, F. E., Manning, M., Sawyer, W. H., Rivier, J. Vasopressor receptor antagonist prevents behavioral-effects of vasopressin Nature 1981 291:491-493 PMID:7231561
- Foote, S. L., Loughlin, S. E., Cohen, P. S., Bloom, F. E., Livingston, R. B. Accurate 3-dimensional reconstruction of neuronal distributions in brain - reconstruction of the rat nucleus locus coeruleus Journal of Neuroscience Methods 1980 3:159-173 DOI:10.1016/0165-0270(80)90023-0 PMID:7206782
- Siggins, G. R., Bloom, F. E. Alcohol-related electrophysiology Pharmacology, Biochemistry and Behavior 1980 13:203-211 PMID:7017760
- Jaimetcheverry, G., Shoemaker, W. J., Zieher, L. M., Bloom, F. E. Antiserum to nerve growth-factor does not prevent the increase of brain-stem noradrenaline after neonatal 6-hydroxydopa Brain Research 1980 197:547-553 DOI:10.1016/0006-8993(80)91145-2 PMID:6773617
- Karobath, M., Rogers, J., Bloom, F. E. Benzodiazepine receptors remain unchanged after chronic ethanol administration Neuropharmacology 1980 19:125-128 DOI:10.1016/0028-3908(80)90177-x PMID:7360326
- Astonjones, G., Segal, M., Bloom, F. E. Brain aminergic axons exhibit marked variability in conduction-velocity Brain Research 1980 195:215-222 DOI:10.1016/0006-8993(80)90880-x PMID:7397496
- Shoemaker, W. J., Koda, L. Y., Shoemaker, C. A., Bloom, F. E. Ethanol effects in chick-embryos - cerebellar purkinje neurons Neurobehavioral Toxicology 1980 2:239-242
- Foote, S. L., Astonjones, G., Bloom, F. E. Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1980 77:3033-3037 DOI:10.1073/pnas.77.5.3033 PMID:6771765
- Schlumpf, M., Shoemaker, W. J., Bloom, F. E. Innervation of embryonic rat cerebral-cortex by catecholamine-containing fibers Journal of Comparative Neurology 1980 192:361-376 DOI:10.1002/cne.901920210 PMID:7400402
- Bloom, F. E., Battenberg, E. L. F., Shibasaki, T., Benoit, R., Ling, N., Guillemin, R. Localization of gamma-melanocyte stimulating hormone (gamma-msh) immunoreactivity in rat-brain and pituitary Regulatory Peptides 1980 1:205-222 DOI:10.1016/0167-0115(80)90272-4 PMID:6262877
- Stinus, L., Koob, G. F., Ling, N., Bloom, F. E., Lemoal, M. Locomotor activation induced by infusion of endorphins into the ventral tegmental area - evidence for opiate-dopamine interactions Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1980 77:2323-2327 DOI:10.1073/pnas.77.4.2323 PMID:6929553
- Pittman, Q. J., Hatton, J. D., Bloom, F. E. Morphine and opioid-peptides reduce paraventricular neuronal-activity - studies on the rat hypothalamic slice preparation Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1980 77:5527-5531 DOI:10.1073/pnas.77.9.5527 PMID:6254087
- Iversen, L. L., Iversen, S. D., Bloom, F. E. Opiate receptors influence vasopressin release from nerve-terminals in rat neurohypophysis Nature 1980 284:350-351 DOI:10.1038/284350a0 PMID:6244503
- Rogers, J., Siggins, G. R., Schulman, J. A., Bloom, F. E. Physiological correlates of ethanol intoxication, tolerance, and dependence in rat cerebellar purkinje-cells Brain Research 1980 196:183-198 DOI:10.1016/0006-8993(80)90725-8 PMID:7190454
- Bayon, A., Koda, L., Battenberg, E., Bloom, F. E. Redistribution of endorphin and enkephalin immunoreactivity in the rat brain and pituitary after in vivo treatment with colchicine or cytochalasin B Brain Research 1980 183:103-111 DOI:10.1016/0006-8993(80)90122-5 PMID:6153550
- Bayon, A., Koda, L., Battenberg, E., Azad, R., Bloom, F. E. Regional distribution of endorphin, met5-enkephalin and leu5-enkephalin in the pigeon brain Neuroscience Letters 1980 16:75-80 DOI:10.1016/0304-3940(80)90104-4 PMID:6763159
- Rogers, J., Silver, M. A., Shoemaker, W. J., Bloom, F. E. Senescent changes in a neurobiological model system - cerebellar purkinje-cell electrophysiology and correlative anatomy Neurobiology of Aging 1980 1:3-11 DOI:10.1016/0197-4580(80)90018-4 PMID:7266732
- Rossier, J., French, E., Rivier, C., Shibasaki, T., Guillemin, R., Bloom, F. E. Stress-induced release of prolactin - blockade by dexamethasone and naloxone may indicate beta-endorphin mediation Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences 1980 77:666-669 DOI:10.1073/pnas.77.1.666 PMID:6244573
- Rossier, J., French, E., Gros, C., Minick, S., Guillemin, R., Bloom, F. E. Adrenalectomy, dexamethasone or stress alters opioid peptides levels in rat anterior-pituitary but not intermediate lobe or brain Life Sciences 1979 25:2105-2112 DOI:10.1016/0024-3205(79)90204-2 PMID:537470
- Moore, R. Y., Bloom, F. E. Central catecholamine neuron systems - anatomy and physiology of the norepinephrine and epinephrine systems Annual Review of Neuroscience 1979 2:113-168 DOI:10.1146/annurev.ne.02.030179.000553 PMID:231924
- Bloom, F. E. Cyclic-nucleotides in central synaptic function Federation Proceedings 1979 38:2203-2207 PMID:221275
- Lemoal, M., Koob, G. F., Bloom, F. E. Endorphins and extinction - differential actions on appetitive and adversive tasks Life Sciences 1979 24:1631-1636 DOI:10.1016/0024-3205(79)90245-5 PMID:481097
- Bloom, F. E., Ueda, T., Battenberg, E., Greengard, P. Immunocytochemical localization, in synapses, of protein-i, an endogenous substrate for protein-kinases in mammalian brain Proceedings of the National Academy of Sciences of the United States of America 1979 76:5982-5986 DOI:10.1073/pnas.76.11.5982 PMID:392512
- Siggins, G. R., Henriksen, S. J., Bloom, F. Iontophoresis of li+ antagonizes noradrenergic synaptic inhibition of rat cerebellar purkinje-cells Proceedings of the National Academy of Sciences of the United States of America 1979 76:3015-3018 DOI:10.1073/pnas.76.6.3015 PMID:288083
- Rogers, J., Wiener, S. G., Bloom, F. E. Long-term ethanol administration methods for rats - advantages of inhalation over intubation or liquid diets Behavioral and Neural Biology 1979 27:466-486 DOI:10.1016/s0163-1047(79)92061-2 PMID:575037
- Rossier, J., Rogers, J., Shibasaki, T., Guillemin, R., Bloom, F. E. Opioid peptides and alpha-melanocyte-stimulating hormone in genetically-obese (ob-ob) mice during development Proceedings of the National Academy of Sciences of the United States of America 1979 76:2077-2080 DOI:10.1073/pnas.76.4.2077 PMID:287046
- Zieglgansberger, W., French, E. D., Siggins, G. R., Bloom, F. E. Opioid peptides may excite hippocampal pyramidal neurons by inhibiting adjacent inhibitory interneurons Science 1979 205:415-417 DOI:10.1126/science.451610 PMID:451610
- Bayon, A., Shoemaker, W. J., Bloom, F. E., Mauss, A., Guillemin, R. Perinatal-development of the endorphin-containing and enkephalin-containing systems in the rat-brain Brain Research 1979 179:93-101 DOI:10.1016/0006-8993(79)90493-1 PMID:509236
- Rossier, J., Bloom, F. E., Guillemin, R. Stimulation of human periaqueductal gray for pain relief increases immunoreactive beta-endorphin in ventricular fluid Science 1979 203:279-281 PMID:83674
- Decamilli, P., Ueda, T., Bloom, F. E., Battenberg, E., Greengard, P. Widespread distribution of protein-i in the central and peripheral nervous systems Proceedings of the National Academy of Sciences of the United States of America 1979 76:5977-5981 PMID:392511 PMCID:PMC411776
- Henriksen, S. J., Bloom, F. E., McCoy, F., Ling, N., Guillemin, R. Beta-endorphin induces non-convulsive limbic seizures Proceedings of the National Academy of Sciences of the United States of America 1978 75:5221-5225 DOI:10.1073/pnas.75.10.5221 PMID:283426
- Moore, R. Y., Bloom, F. E. Central catecholamine neuron systems - anatomy and physiology of the dopamine systems Annual Review of Neuroscience 1978 1:129-169 DOI:10.1146/annurev.ne.01.030178.001021 PMID:756202
- Robinson, R. G., Bloom, F. E. Changes in posterior hypothalamic self-stimulation following experimental cerebral infarction in rat Journal of Comparative and Physiological Psychology 1978 92:969-976 DOI:10.1037/h0077541 PMID:730862
- Jacobs, B. L., Foote, S. L., Bloom, F. E. Differential projections of neurons within dorsal raphe nucleus of rat - a horseradish-peroxidase (hrp) study Brain Research 1978 147:149-153 DOI:10.1016/0006-8993(78)90779-5 PMID:77700
- Bayon, A., Rossier, J., Mauss, A., Bloom, F. E., Iversen, L. L., Ling, N., Guillemin, R. In vitro release of 5-methionine enkephalin and 5-leucine -enkephalin from rat globus pallidus Proceedings of the National Academy of Sciences of the United States of America 1978 75:3503-3506 DOI:10.1073/pnas.75.7.3503 PMID:277953
- Koda, L. Y., Wise, R. A., Bloom, F. E. Light and electron-microscopic changes in rat dentate gyrus after lesions or stimulation of ascending locus coeruleus pathway Brain Research 1978 144:363-368 DOI:10.1016/0006-8993(78)90162-2 PMID:638766
- Iversen, L. L., Iversen, S. D., Bloom, F. E., Vargo, T., Guillemin, R. Release of enkephalin from rat globus pallidus in vitro Nature 1978 271:679-681 DOI:10.1038/271679a0 PMID:24182
- Koda, L. Y., Koob, G. F., Shier, W. T., Bloom, F. E. Tetrahydropapaveroline induces small granular vesicles in brain dopamine fibers Nature 1978 276:281-283 DOI:10.1038/276281a0 PMID:714160
- Koda, L. Y., Schulman, J. A., Bloom, F. E. Ultrastructural identification of noradrenergic terminals in rat hippocampus - unilateral destruction of locus coeruleus with 6-hydroxydopamine Brain Research 1978 145:190-195 DOI:10.1016/0006-8993(78)90810-7 PMID:638778
- Schlumpf, M., Shoemaker, W. J., Bloom, F. E. Explant cultures of catecholamine-containing neurons from rat-brain - biochemical, histofluorescence, and electron-microscopic studies Proceedings of the National Academy of Sciences of the United States of America 1977 74:4471-4475 DOI:10.1073/pnas.74.10.4471 PMID:270693
- Robinson, R. G., Bloom, F. E., Battenberg, E. L. F. Fluorescent histochemical study of changes in noradrenergic neurons following experimental cerebral infarction in rat Brain Research 1977 132:259-272 DOI:10.1016/0006-8993(77)90420-6 PMID:890481
- Rossier, J., French, E. D., Rivier, C., Ling, N., Guillemin, R., Bloom, F. E. Foot-shock induced stress increases beta-endorphin levels in blood but not brain Nature 1977 270:618-620 DOI:10.1038/270618a0 PMID:201864
- Koda, L. Y., Bloom, F. E. Light and electron-microscopic study of noradrenergic terminals in rat dentate gyrus Brain Research 1977 120:327-335 DOI:10.1016/0006-8993(77)90910-6 PMID:832125
- Bloom, F. E. Neural mechanisms of benzodiazepine actions American Journal of Psychiatry 1977 134:669-672 PMID:17306
- Nicoll, R. A., Siggins, G. R., Ling, N., Bloom, F. E., Guillemin, R. Neuronal actions of endorphins and enkephalins among brain-regions - comparative microiontophoretic study Proceedings of the National Academy of Sciences of the United States of America 1977 74:2584-2588 DOI:10.1073/pnas.74.6.2584 PMID:267951
- Hall, R. D., Bloom, F. E., Olds, J. Neuronal and neurochemical substrates of reinforcement Neurosciences Research Program Bulletin 1977 15:139-314
- Bloom, F. E. Peptide transmitters - clues to chemical cryptogram of interneuronal communication Biosystems 1977 8:179-183 DOI:10.1016/0303-2647(77)90036-3 PMID:18227
- Robinson, R. G., Bloom, F. E. Pharmacological treatment following experimental cerebral infarction - implications for understanding psychological symptoms of human stroke Biological Psychiatry 1977 12:669-680 PMID:588647
- Rossier, J., Vargo, T. M., Minick, S., Ling, N., Bloom, F. E., Guillemin, R. Regional dissociation of beta-endorphin and enkephalin contents in rat-brain and pituitary Proceedings of the National Academy of Sciences of the United States of America 1977 74:5162-5165 DOI:10.1073/pnas.74.11.5162 PMID:270754
- Segal, M., Bloom, F. E. Action of norepinephrine in rat hippocampus .3. Hippocampal cellular responses to locus coeruleus stimulation in awake rat Brain Research 1976 107:499-511 DOI:10.1016/0006-8993(76)90140-2 PMID:178410
- Segal, M., Bloom, F. E. Action of norepinephrine in rat hippocampus .4. Effects of locus coeruleus stimulation on evoked hippocampal unit-activity Brain Research 1976 107:513-525 DOI:10.1016/0006-8993(76)90141-4 PMID:178411
- Nathanson, J. A., Bloom, F. E. Heavy-metals and adenosine cyclic 3',5'-monophosphate metabolism - possible relevance to heavy-metal toxicity Molecular Pharmacology 1976 12:390-398 PMID:180396
- Bloom, F. E. Possible sites in neuron for interactions of drugs of abuse Annals of the New York Academy of Sciences 1976 281:11-23 DOI:10.1111/j.1749-6632.1976.tb27916.x PMID:1071363
- Bloom, F. E., Battenberg, E. L. F. Rapid, simple and sensitive method for demonstration of central catecholamine-containing neurons and axons by glyoxylic acid-induced fluorescence .2. Detailed description of methodology Journal of Histochemistry & Cytochemistry 1976 24:561-571 PMID:1270793
- Landis, S. C., Shoemaker, W. J., Schlumpf, M., Bloom, F. E. Catecholamines in mutant mouse cerebellum - fluorescence microscopic and chemical studies Brain Research 1975 93:253-266 DOI:10.1016/0006-8993(75)90349-2 PMID:1174970
- Shoemaker, W. J., Balentine, L. T., Siggins, G. R., Hoffer, B. J., Henriksen, S. J., Bloom, F. E. Characteristics of release of adenosine 3'-5' - monophosphate from micropipets by microiontophoresis Journal of Cyclic Nucleotide Research 1975 1:97-106 PMID:4474
- Robinson, R. G., McHugh, P. R., Bloom, F. E. Chlorpromazine induced hyperphagia in rat Psychopharmacology Communications 1975 1:37-50 PMID:1223991
- Stone, T. W., Taylor, D. A., Bloom, F. E. Cyclic-amp and cyclic-gmp may mediate opposite neuronal responses in rat cerebral-cortex Science 1975 187:845-847 DOI:10.1126/science.163488 PMID:163488
- Robinson, R. G., Shoemaker, W. J., Schlumpf, M., Valk, T., Bloom, F. E. Effect of experimental cerebral infarction in rat-brain on catecholamines and behavior Nature 1975 255:332-334 DOI:10.1038/255332a0 PMID:1128692
- Freedman, R., Foote, S. L., Bloom, F. E. Histochemical characterization of a neocortical projection of nucleus locus coeruleus in squirrel-monkey Journal of Comparative Neurology 1975 164:209-231 DOI:10.1002/cne.901640205 PMID:810499
- Goodman, D. B. P., Bloom, F. E., Battenberg, E. R., Rasmussen, H., Davis, W. L. Immunofluorescent localization of cyclic-amp in toad urinary-bladder - possible intercellular transfer Science 1975 188:1023-1025 DOI:10.1126/science.167437 PMID:167437
- Nathanson, J. A., Bloom, F. E. Lead-induced inhibition of brain adenyl-cyclase Nature 1975 255:419-420 DOI:10.1038/255419a0 PMID:165434
- Bloom, F. E. Modern concepts in electrophysiology for psychiatry Psychopharmacology Communications 1975 1:579-585 PMID:817377
- Bloom, F. E. Monoaminergic neurotoxins - are they selective Journal of Neural Transmission 1975 37:183-187 DOI:10.1007/bf01670127 PMID:1185164
- Kebabian, J. W., Bloom, F. E., Steiner, A. L., Greengard, P. Neurotransmitters increase cyclic nucleotides in postganglionic neurons - immunocytochemical demonstration Science 1975 190:157-159 DOI:10.1126/science.241121 PMID:241121
- Lauder, J. M., Bloom, F. E. Ontogeny of monoamine neurons in locus coeruleus, raphe nuclei and substantia nigra of rat .2. Synaptogenesis Journal of Comparative Neurology 1975 163:251-264 DOI:10.1002/cne.901630302 PMID:240873
- Battenberg, E. L. F., Bloom, F. E. Rapid, simple and more sensitive method for demonstration of central catecholamine-containing neurons and axons by glyoxylic-acid induced fluorescence .1. Specificity Psychopharmacology Communications 1975 1:3-13 PMID:1223990
- Bloom, F. E. Role of cyclic nucleotides in central synaptic function Reviews of Physiology Biochemistry and Pharmacology 1975 74:1-103 PMID:1841
- Landis, S. C., Bloom, F. E. Ultrastructural identification of noradrenergic boutons in mutant and normal mouse cerebellar cortex Brain Research 1975 96:299-305 DOI:10.1016/0006-8993(75)90738-6 PMID:1175014
- Segal, M., Bloom, F. E. Action of norepinephrine in rat hippocampus .1. Iontophoretic studies Brain Research 1974 72:79-97 DOI:10.1016/0006-8993(74)90652-0 PMID:4364476
- Segal, M., Bloom, F. E. Action of norepinephrine in rat hippocampus .2. Activation of input pathway Brain Research 1974 72:99-114 DOI:10.1016/0006-8993(74)90653-2 PMID:4364477
- Chu, N. S., Bloom, F. E. Activity patterns of catecholamine-containing pontine neurons in dorsolateral tegmentum of unrestrained cats Journal of Neurobiology 1974 5:527-544 DOI:10.1002/neu.480050605 PMID:4373534
- Pickel, V. M., Segal, M., Bloom, F. E. Autoradiographic study of efferent pathways of nucleus locus coeruleus Journal of Comparative Neurology 1974 155:15-41 DOI:10.1002/cne.901550103 PMID:4836061
- Pickel, V. M., Segal, M., Bloom, F. E. Axonal proliferation following lesions of cerebellar peduncles - combined fluorescence microscopic and autoradiographic study Journal of Comparative Neurology 1974 155:43-59 DOI:10.1002/cne.901550104 PMID:4836062
- Chu, N. S., Bloom, F. E. Catecholamine-containing neurons in cat dorsolateral pontine tegmentum: distribution of cell bodies and some axonal projections Brain Research 1974 66:1-21 DOI:10.1016/0006-8993(74)90075-4
- Sheu, Y. S., Nelson, J. P., Bloom, F. E. Discharge patterns of cat raphe neurons during sleep and waking Brain Research 1974 73:263-276 DOI:10.1016/0006-8993(74)91048-8 PMID:4364625
- Bloom, F. E., Siggins, G. R., Hoffer, B. J. Interpreting failures to confirm depression of cerebellar purkinje-cells by cyclic-amp Science 1974 185:627-629 DOI:10.1126/science.185.4151.627 PMID:4366788
- Kauffman, F. C., Pickel, V. M., Sims, K. L., Bloom, F. E. Localization of nicotinamide adenine-dinucleotide phosphate-dependent dehydrogenases in catecholamine-containing neurons of rat-brain - studies on nucleus locus ceruleus Journal of Histochemistry & Cytochemistry 1974 22:20-28 PMID:4133068
- Lauder, J. M., Bloom, F. E. Ontogeny of monoamine neurons in locus coeruleus, raphe nuclei and substantia nigra of rat .1. Cell-differentiation Journal of Comparative Neurology 1974 155:469-481 DOI:10.1002/cne.901550407 PMID:4847734
- Bloom, F. E. To spritz or not to spritz - doubtful value of aimless iontophoresis Life Sciences 1974 14:1819-1834 DOI:10.1016/0024-3205(74)90400-7 PMID:4368008
- Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Activation of pathway from locus coeruleus to rat cerebellar purkinje neurons - pharmacological evidence of noradrenergic central inhibition Journal of Pharmacology and Experimental Therapeutics 1973 184:553-569 PMID:4347049
- Sims, K. L., Davis, G. A., Bloom, F. E. Activities of 3,4-dihydroxy-l-phenylalanine and 5-hydroxy-l-tryptophan decarboxylases in rat-brain - assay characteristics and distribution Journal of Neurochemistry 1973 20:449-464 DOI:10.1111/j.1471-4159.1973.tb12144.x PMID:4540567
- Nelson, C. N., Hoffer, B. J., Chu, N. S., Bloom, F. E. Cytochemical and pharmacological studies on polysensory neurons in primate frontal cortex Brain Research 1973 62:115-133 DOI:10.1016/0006-8993(73)90623-9 PMID:4148775
- Hanker, J. S., Kusyk, C. J., Bloom, F. E., Pearse, A. G. E. Demonstration of dehydrogenases and monoamine-oxidase by formation of osmium blacks at sites of hatchetts brown Histochemie 1973 33:205-230 PMID:4119081
- Bloom, F. E. Dynamic synaptic communication - finding vocabulary Brain Research 1973 62:299-305 DOI:10.1016/0006-8993(73)90690-2 PMID:4148549
- Davis, G. A., Bloom, F. E. Isolation of synaptic junctional complexes from rat-brain Brain Research 1973 62:135-153 DOI:10.1016/0006-8993(73)90624-0 PMID:4128804
- Siggins, G. R., Battenberg, E. F., Hoffer, B. J., Bloom, F. E., Steiner, A. L. Noradrenergic stimulation of cyclic adenosine monophosphate in rat purkinje neurons: An immunocytochemical study Science 1973 179:585-588 DOI:10.1126/science.179.4073.585 PMID:4346826
- Chu, N., Bloom, F. E. Norepinephrine-containing neurons - changes in spontaneous discharge patterns during sleeping and waking Science 1973 179:908-910 DOI:10.1126/science.179.4076.908 PMID:4347167
- Pickel, V. M., Krebs, H., Bloom, F. E. Proliferation of norepinephrine-containing axons in rat cerebellar cortex after peduncle lesions Brain Research 1973 59:169-179 DOI:10.1016/0006-8993(73)90258-8 PMID:4747749
- Sims, K. L., Bloom, F. E. Rat-brain l-3,4-dihydroxyphenylalanine and l-5-hydroxy-tryptophan decarboxylase activities - differential effect of 6-hydroxydopamine Brain Research 1973 49:165-175 DOI:10.1016/0006-8993(73)90408-3 PMID:4540548
- Davis, G. A., Bloom, F. E. Subcellular particles separated through a histochemical reaction Analytical Biochemistry 1973 51:429-435 DOI:10.1016/0003-2697(73)90496-x PMID:4700192
- Bloom, F. E. Ultrastructural identification of catecholamine-containing central synaptic terminals Journal of Histochemistry & Cytochemistry 1973 21:333-348 PMID:4122462
- Bloom, F. E., Wedner, H. J., Parker, C. W. Use of antibodies to study cell structure and metabolism Pharmacological Reviews 1973 25:343-358 PMID:4361228
- Bloom, F. E., Hoffer, B. J., Battenberg, E. R., Siggins, G. R., Steiner, A. L., Parker, C. W., Wedner, H. J. Adenosine 3',5'-monophosphate is localized in cerebellar neurons: Immunofluorescence evidence Science 1972 177:436-438 DOI:10.1126/science.177.4047.436 PMID:4339615
- Silberstein, S. D., Johnson, D. G., Bloom, F. E., Kopin, I. J., Hanbauer, I. Axonal sprouts and [3h]norepinephrine uptake by superior cervical ganglia in organ culture Proceedings of the National Academy of Sciences of the United States of America 1972 69:1450-1455 DOI:10.1073/pnas.69.6.1450 PMID:4504357 PMCID:PMC426723
- Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Cyclic AMP-mediated adrenergic synapses to cerebellar Purkinje cells Advances in Cyclic Nucleotide Research 1972 1:411-423 PMID:4353180
- Bloom, F. E., Barker, J. L., Hoffer, B. J., Siggins, G. R., Nicoll, R. A. Effects of serotonin on central neurons: Microiontophoretic administration Federation Proceedings 1972 31:97-106 PMID:4333253
- Sims, K. L., Weitsen, H. A., Bloom, F. E. Gaba catabolism: Localization of succinic semialdehyde dehydrogenase in brain motor and sensory nuclei Science 1972 175:1479-1480 DOI:10.1126/science.175.4029.1479 PMID:5013679
- Aghajanian, G. K., Bloom, F. E., Haigler, H. J. Lysergic-acid diethylamide and serotonin - direct action on serotonin-containing neurons in rat-brain Life Science Part 1 Physiology & Pharmacology 1972 11:615-622 DOI:10.1016/0024-3205(72)90153-1
- Bloom, F. E., Hoffer, B. J., Siggins, G. R. Norepinephrine mediated cerebellar synapses: A model system for neuropsychopharmacology Biological Psychiatry 1972 4:157-177 PMID:4337435
- Hanker, J. S., Anderson, W. A., Bloom, F. E. Osmiophilic polymer generation: Catalysis by transition metal compounds in ultrastructural cytochemistry Science 1972 175:991-993 DOI:10.1126/science.175.4025.991 PMID:5009401
- Iversen, L. L., Bloom, F. E. Studies of the uptake of 3 h-gaba and ( 3 h)glycine in slices and homogenates of rat brain and spinal cord by electron microscopic autoradiography Brain Research 1972 41:131-143 DOI:10.1016/0006-8993(72)90621-x PMID:5036031
- Siggins, G. R., Hoffer, B. J., Oliver, A. P., Bloom, F. E. Activation of a central noradrenergic projection to cerebellum Nature 1971 233:481-483 DOI:10.1038/233481a0 PMID:4939543
- Godfraind, J. M., Pumain, R., Siggins, G. R., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate and norepinephrine: Effect on purkinje cells in rat cerebellar cortex Science 1971 174:1257-1259 PMID:4332286
- Siggins, G. R., Oliver, A. P., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate and norepinephrine: Effects on transmembrane properties of cerebellar purkinje cells Science 1971 171:192-194 DOI:10.1126/science.171.3967.192 PMID:4322158
- Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Cyclic amp mediation of norepinephrine inhibition in rat cerebellar cortex: A unique class of synaptic responses Annals of the New York Academy of Sciences 1971 185:531-549 PMID:4330518
- Sims, K. L., Weitsen, H. A., Bloom, F. E. Histochemical localization of brain succinic semialdehyde dehydrogenase-a gamma-aminobutyric acid degradative enzyme Journal of Histochemistry & Cytochemistry 1971 19:405-415 DOI:10.1177/19.7.405 PMID:4105040
- Bloom, F. E., Iversen, L. L. Localizing h-3-gaba in nerve terminals of rat cerebral cortex by electron microscopic autoradiography Nature 1971 229:628-630 DOI:10.1038/229628a0 PMID:4925465
- Siggins, G., Hoffer, B., Bloom, F. Prostaglandin-norepinephrine interactions in brain: Microelectrophoretic and histochemical correlates Annals of the New York Academy of Sciences 1971 180:302-323 DOI:10.1111/j.1749-6632.1971.tb53199.x PMID:5286100
- Hoffer, B. J., Siggins, G. R., Woodward, D. J., Bloom, F. E. Spontaneous discharge of purkinje neurons after destruction of catecholamine-containing afferents by 6-hydroxydopamine Brain Research 1971 30:425-430 DOI:10.1016/0006-8993(71)90095-3 PMID:4329214
- Bloom, F. E., Hoffer, B. J., Siggins, G. R. Studies on norepinephrine-containing afferents to purkinje cells of art cerebellum. I. Localization of the fibers and their synapses Brain Research 1971 25:501-521 DOI:10.1016/0006-8993(71)90457-4 PMID:5544323
- Siggins, G. R., Hoffer, B. J., Bloom, F. E. Studies on norepinephrine-containing afferents to purkinje cells of rat cerebellum. 3. Evidence for mediation of norepinephrine effects by cyclic 3',5'-adenosine monophosphate Brain Research 1971 25:535-553 DOI:10.1016/0006-8993(71)90459-8 PMID:4322679
- Hoffer, B. J., Siggins, G. R., Bloom, F. E. Studies on norepinephrine-containing afferents to purkinje cells of rat cerebellum. Ii. Sensitivity of purkinje cells to norepinephrine and related substances administered by microiontophoresis Brain Research 1971 25:523-534 DOI:10.1016/0006-8993(71)90458-6 PMID:4395919
- Woodward, D. J., Hoffer, B. J., Siggins, G. R., Bloom, F. E. The ontogenetic development of synaptic junctions, synaptic activation and responsiveness to neurotransmitter substances in rat cerebellar purkinje cells Brain Research 1971 34:73-97 DOI:10.1016/0006-8993(71)90352-0 PMID:4330971
- Shorr, S. S., Bloom, F. E. Acino-insular cells in normal rat pancreas Yale Journal of Biology and Medicine 1970 43:47-49 PMID:4918984 PMCID:PMC2591532
- Siggins, G. R., Bloom, F. E. Cytochemical and physiological effects of 6-hydroxydopamine on periarteriolar nerves of frogs Circulation Research 1970 27:23-38 PMID:5424564
- Shorr, S. S., Bloom, F. E. Fine structure of islet-cell innervation in the pancreas of normal and alloxan-treated rats Zeitschrift für Zellforschung und Mikroskopische Anatomie 1970 103:12-25 DOI:10.1007/bf00335397 PMID:4904355
- Stjarne, L., Roth, R. H., Bloom, F. E., Giarman, N. J. Norepinephrine concentrating mechanisms in sympathetic nerve trunks Journal of Pharmacology and Experimental Therapeutics 1970 171:70-79 PMID:5410939
- Bloom, F. E., Giarman, N. J. The effects of p-Cl-phenylalanine on the content and cellular distribution of 5-HT in the rat pineal gland: combined biochemical and electron microscopic analyses Biochemical Pharmacology 1970 19:1213-1219 DOI:10.1016/0006-2952(70)90381-3
- Boadle, M. C., Bloom, F. E. A method for the fine structural localization of monoamine oxidase Journal of Histochemistry & Cytochemistry 1969 17:331-340 PMID:4896953
- Siggins, G. R., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate: Possible mediator for norepinephrine effects on cerebellar purkinje cells Science 1969 165:1018-1020 DOI:10.1126/science.165.3897.1018 PMID:4308638
- Aghajanian, G. K., Bloom, F. E., Sheard, M. H. Electron microscopy of degeneration within the serotonin pathway of rat brain Brain Research 1969 13:266-273 DOI:10.1016/0006-8993(69)90286-8 PMID:5772424
- Bloom, F. E., Algeri, S., Groppetti, A., Revuelta, A., Costa, E. Lesions of central norepinephrine terminals with 6-oh-dopamine: Biochemistry and fine structure Science 1969 166:1284-1286 DOI:10.1126/science.166.3910.1284 PMID:5350323
- Hoffer, B. J., Siggins, G. R., Bloom, F. E. Prostaglandins e1 and e2 antagonize norepinephrine effects on cerebellar purkinje cells: Microelectrophoretic study Science 1969 166:1418-1420 DOI:10.1126/science.166.3911.1418 PMID:5350346
- Hughes, J., Gillis, C. N., Bloom, F. E. The uptake and disposition of dl-norepinephrine in perfused rat lung Journal of Pharmacology and Experimental Therapeutics 1969 169:237-248 PMID:5824606
- Bloom, F. E., Aghajanian, G. K. An electron microscopic analysis of large granular synaptic vesicles of the brain in relation to monoamine content Journal of Pharmacology and Experimental Therapeutics 1968 159:261-273 PMID:5638647
- Bloom, F. E., Aghajanian, G. K. An osmiophilic substance in brain synaptic vesicles not associated with catecholamine content Experientia 1968 24:1225-1227 DOI:10.1007/bf02146636 PMID:5703021
- Bloom, F. E., Aghajanian, G. K. Fine structural and cytochemical analysis of the staining of synaptic junctions with phosphotungstic acid Journal of Ultrastructure Research 1968 22:361-375 DOI:10.1016/s0022-5320(68)90027-0 PMID:4173151
- Roth, R. H., Stjarne, L., Bloom, F. E., Giarman, N. J. Light and heavy norepinephrine storage particles in the rat heart and in bovine splenic nerve Journal of Pharmacology and Experimental Therapeutics 1968 162:203-212 PMID:5666978
- Bloom, F. E., Giarman, N. J. Physiologic and pharmacologic considerations of biogenic amines in the nervous system Annual Review of Pharmacology 1968 8:229-258 DOI:10.1146/annurev.pa.08.040168.001305 PMID:5302125
- Aghajanian, G. K., Bloom, F. E. Electron-microscopic localization of tritiated norepinephrine in rat brain: Effect of drugs Journal of Pharmacology and Experimental Therapeutics 1967 156:407-416 PMID:6027453
- Aghajanian, G. K., Bloom, F. E. Localization of tritiated serotonin in rat brain by electron-microscopic autoradiography Journal of Pharmacology and Experimental Therapeutics 1967 156:23-30 PMID:6023598
- Morris, N. R., Aghajanian, G. K., Bloom, F. E. Magnesium pemoline: Failure to affect in vivo synthesis of brain rna Science 1967 155:1125-1126 DOI:10.1126/science.155.3766.1125 PMID:4381484
- Bloom, F. E., Barrnett, R. J. The fine structural localization of cholinesterases in nervous tissue Annals of the New York Academy of Sciences 1967 144:626-645 DOI:10.1111/j.1749-6632.1967.tb53799.x
- Bloom, F. E., Aghajanian, G. K. Cytochemistry of synapses: Selective staining for electron microscopy Science 1966 154:1575-1577 DOI:10.1126/science.154.3756.1575 PMID:5924927
- Aghajanian, G. K., Bloom, F. E. Electron-microscopic autoradiography of rat hypothalamus after intraventricular h3-norepinephrine Science 1966 153:308-310 DOI:10.1126/science.153.3733.308 PMID:17780004
- Bloom, F. E., Barrnett, R. J. Fine structural localization of acetylcholinesterase in electroplaque of the electric eel Journal of Cell Biology 1966 29:475-495 DOI:10.1083/jcb.29.3.475 PMID:5962939 PMCID:PMC2106980
- Bloom, F. E., Barrnett, R. J. Fine structural localization of noradrenaline in vesicles of autonomic nerve endings Nature 1966 210:599-601 DOI:10.1038/210599a0 PMID:6007247
- Van Orden, L. S. 3rd, Bloom, F. E., Barrnett, R. J., Giarman, N. J. Histochemical and functional relationships of catecholamines in adrenergic nerve endings. I. Participation of granular vesicles Journal of Pharmacology and Experimental Therapeutics 1966 154:185-199 PMID:5950955
- Aghajanian, G. K., Bloom, F. E., Lovell, R. A., Sheard, M. H., Freedman, D. X. The uptake of 5-hydroxytryptamine-(3)H from the cerebral ventricles: autoradiographic localization Biochemical Pharmacology 1966 15:1401-1403 DOI:10.1016/0006-2952(66)90051-7
- Bloom, F. E., Costa, E., Salmoiraghi, G. C. Anesthesia and the responsiveness of individual neurons of the caudate nucleus of the cat to acetylcholine, norepinephrine and dopamine administered by microelectrophoresis Journal of Pharmacology and Experimental Therapeutics 1965 150:244-252 PMID:5855881
- Salmoiraghi, G. C., Costa, E., Bloom, F. E. Pharmacology of central synapses Annual Review of Pharmacology 1965 5:213-234 DOI:10.1146/annurev.pa.05.040165.001241 PMID:14287881
- Salmoiraghi, G. C., Bloom, F. E., Costa, E. Adrenergic mechanisms in rabbit olfactory bulb American Journal of Physiology 1964 207:1417-1424 PMID:14251955
- Bloom, F. E., Costa, E., Salmoiraghi, G. C. Analysis of individual rabbit olfactory bulb neuron responses to the microelectrophoresis of acetylcholine, norepinephrine and serotonin synergists and antagonists Journal of Pharmacology and Experimental Therapeutics 1964 146:16-23 PMID:14221220
- Bloom, F. E., Baumgarten, R. V., Oliver, A. P., Costa, E., Salmoiraghi, G. C. Microelectrophoretic studies of adrenergic mechanisms of rabbit olfactory neurons Life Sciences 1964 3:131-136 DOI:10.1016/0024-3205(64)90192-4 PMID:14148134
- Salmoiraghi, G. C., Bloom, F. E. Pharmacology of individual neurons: Microelectrophoresis provides closer observation of interactions between nerve cells and drugs Science 1964 144:493-499 DOI:10.1126/science.144.3618.493 PMID:14197558
- Bloom, F. E., Schoepfle, G. M. Kinetics of procaine-acetylcholine antagonism American Journal of Physiology 1963 204:73-76 PMID:13971781
- Baumgarten, R. V., Salmoiraghi, G. C., Bloom, F. E., Oliver, A. P. Response of individual olfactory nerve cells to microelectrophoretically administered chemical substances Pflugers Archiv-European Journal of Physiology 1963 277:125-140 DOI:10.1007/BF00363371
- Bloom, F. E., Oliver, A. P., Salmoiraghi, G. C. The responsiveness of individual hypothalamic neurons to microelectrophoretically administered endogenous amines International Journal of Neuropharmacology 1963 2:181-193 DOI:10.1016/0028-3908(63)90019-4
- Schoepfle, G. M., Bloom, F. E. Effects of cyanide and dinitrophenol on membrane properties of single nerve fibers American Journal of Physiology 1959 197:1131-1135 PMID:14443394
- Schoepfle, G. M., Bloom, F. E., Hellam, D. Kinetics of the negative after-potential in frog single nerve fibers American Journal of Physiology 1958 193:195-202 PMID:13521007