academic article

• Ledbetter, M. P., Craig, J. M., Karadeema, R. J., Noakes, M. T., Kim, H. C., Abell, S. J., Huang, J. R., Anderson, B. A., Krishnamurthy, R., Gundlach, J. H., Romesberg, F. E. Nanopore sequencing of an expanded genetic alphabet reveals high-fidelity replication of a predominantly hydrophobic unnatural base pair Journal of the American Chemical Society  2020 142:2110-2114  DOI:10.1021/jacs.9b09808  PMID:31985216
• Fischer, E. C., Hashimoto, K., Zhang, Y., Feldman, A. W., Dien, V. T., Karadeema, R. J., Adhikary, R., Ledbetter, M. P., Krishnamurthy, R., Romesberg, F. E. New codons for efficient production of unnatural proteins in a semisynthetic organism Nature Chemical Biology  2020 16:570-576  DOI:10.1038/s41589-020-0507-z  PMID:32251411
• Shao, Q., Chen, T., Sheng, K., Liu, Z., Zhang, Z., Romesberg, F. E. Selection of aptamers with large hydrophobic 2'-substituents Journal of the American Chemical Society  2020 142:2125-2128  DOI:10.1021/jacs.9b10538  PMID:31961667
• Walsh, S. I., Peters, D. S., Smith, P. A., Craney, A., Dix, M. M., Cravatt, B. F., Romesberg, F. E. Inhibition of protein secretion in Escherichia coli and sub-MIC effects of arylomycin antibiotics Antimicrobial Agents and Chemotherapy  2019 63:e01253-18  DOI:10.1128/aac.01253-18  PMID:30420476  PMCID:PMC6355593
• Feldman, A. W., Dien, V. T., Karadeema, R. J., Fischer, E. C., You, Y., Anderson, B. A., Krishnamurthy, R., Chen, J. S., Li, L., Romesberg, F. E. Optimization of replication, transcription, and translation in a semi-synthetic organism Journal of the American Chemical Society  2019 141:10644-10653  DOI:10.1021/jacs.9b02075  PMID:31241334
• Zhou, A. X. Z., Sheng, K., Feldman, A. W., Romesberg, F. E. Progress toward eukaryotic semisynthetic organisms: translation of unnatural codons Journal of the American Chemical Society  2019 141:20166-20170  DOI:10.1021/jacs.9b09080
• Ledbetter, M. P., Malyshev, D. A., Romesberg, F. E. Site-specific labeling of DNA via PCR with an expanded genetic alphabet Methods in Molecular Biology  2019 1973:193-212  DOI:10.1007/978-1-4939-9216-4_13  PMID:31016704 
• Adhikary, R., Zimmermann, J., Stanfield, R. L., Wilson, I. A., Yu, W., Oda, M., Romesberg, F. E. Structure and dynamics of stacking interactions in an antibody binding site Biochemistry  2019 58:2987-2995  DOI:10.1021/acs.biochem.9b00119  PMID:31243995
• Romesberg, F. E. Synthetic Biology: The chemist's approach Israel Journal of Chemistry  2019 59:91-94  DOI:10.1002/ijch.201900014
• Ledbetter, M. P., Romesberg, F. E. Editorial overview: Expanding the genetic alphabet and code Current Opinion in Chemical Biology  2018 46:A1-A2  DOI:10.1016/j.cbpa.2018.09.007  PMID:30270151
• Dien, V. T.*, Morris, S. E.*, Karadeemal, R. J., Romesberg, F. E. Expansion of the genetic code via expansion of the genetic alphabet Current Opinion in Chemical Biology  2018 46:196-202  DOI:10.1016/j.cbpa.2018.08.009  PMID:30205312 (* = equal contribution)
• Dien, V. T., Holcomb, M., Feldman, A. W., Fischer, E. C., Dwyer, T. J., Romesberg, F. E. Progress toward a semi-synthetic organism with an unrestricted expanded genetic alphabet Journal of the American Chemical Society  2018 140:16115-16123  DOI:10.1021/jacs.8b08416  PMID:30418780
• White, R. F., Steele, L., O'Callaghan, J. P., Sullivan, K., Binns, J. H., Golomb, B. A., Bloom, F. E., Bunker, J. A., Crawford, F., Graves, J. C., Hardie, A., Klimas, N., et al. Recent research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effects of toxicant exposures during deployment Cortex  2016 74:449-475  DOI:10.1016/j.cortex.2015.08.022  PMID:26493934  PMCID:PMC4724528
• Bloom, F. E. Mentored and inspired by Mimo: A tribute to Erminio Costa Neuropharmacology  2011 60:1003-1006  DOI:10.1016/j.neuropharm.2010.09.019  PMID:20869374
• Sutcliffe, J. G., Hedlund, P. B., Thomas, E. A., Bloom, F. E., Hilbush, B. S. Peripheral reduction of beta-amyloid is sufficient to reduce brain beta-amyloid: Implications for alzheimer's disease Journal of Neuroscience Research  2011 89:808-814  DOI:10.1002/jnr.22603  PMID:21374699
• Bloom, F. E. The catecholamine neuron: Historical and future perspectives Progress in Neurobiology  2010 90:75-81  DOI:10.1016/j.pneurobio.2009.10.014  PMID:19853013
• Broide, R. S., Redwine, J. M., Aftahi, N., Young, W., Bloom, F. E., Winrow, C. J. Distribution of histone deacetylases 1-11 in the rat brain Journal of Molecular Neuroscience  2007 31:47-58  DOI:10.1385/jmn/31:01:47  PMID:17416969
• Jacobsen, J. S., Wu, C. C., Redwine, J. M., Comery, T. A., Arias, R., Bowlby, M., Martone, R., Morrison, J. H., Pangalos, M. N., Reinhart, P. H., Bloom, F. E. Early-onset behavioral and synaptic deficits in a mouse model of alzheimer's disease Proceedings of the National Academy of Sciences of the United States of America  2006 103:5161-5166  DOI:10.1073/pnas.0600948103  PMID:16549764  PMCID:PMC1405622
• Bloom, F. E., Morrison, J. H., Young, W. G. Neuroinformatics: A new tool for studying the brain Journal of Affective Disorders  2006 92:133-138  DOI:10.1016/j.jad.2005.12.043  PMID:16488481
• Zapala, M. A., Hovatta, I., Ellison, J. A., Wodicka, L., Del Rio, J. A., Tennant, R., Tynan, W., Broide, R. S., Helton, R., Stoveken, B. S., Winrow, C., Lockhart, D. J., et al. Adult mouse brain gene expression patterns bear an embryologic imprint Proceedings of the National Academy of Sciences of the United States of America  2005 102:10357-10362  DOI:10.1073/pnas.0503357102  PMID:16002470  PMCID:PMC1173363
• Bloom, F. E., Reilly, J. F., Redwine, J. M., Wu, C. C., Young, W. G., Morrison, J. H. Mouse models of human neurodegenerative disorders - requirements for medication development Archives of Neurology  2005 62:185-187  DOI:10.1001/archneur.62.2.185  PMID:15710845
• Wu, C. C., Reilly, J. F., Young, W. G., Morrison, J. H., Bloom, F. E. High-throughput morphometric analysis of individual neurons Cerebral Cortex  2004 14:543-554  DOI:10.1093/cercor/bhh016  PMID:15054070
• Engelmann, M., Wolf, G., Putzke, J., Bloom, F. E., Raber, J., Landgraf, R., Spina, M. G., Horn, T. F. W. Nitric oxide is not involved in the control of vasopressin release during acute forced swimming in rats Amino Acids  2004 26:37-43  DOI:10.1007/s00726-003-0040-x  PMID:14752614
• Wu, C. C., Chawla, F., Games, D., Rydel, R. E., Freedman, S., Schenk, D., Young, W. G., Morrison, J. H., Bloom, F. E. Selective vulnerability of dentate granule cells prior to amyloid deposition in pdapp mice: Digital morphometric analyses Proceedings of the National Academy of Sciences of the United States of America  2004 101:7141-7146  DOI:10.1073/pnas.0402147101  PMID:15118092  PMCID:PMC406479
• Broide, R. S., Trembleau, A., Ellison, J. A., Cooper, J., Lo, D., Young, W. G., Morrison, J. H., Bloom, F. E. Standardized quantitative in situ hybridization using radioactive oligonucleotide probes for detecting relative levels of mrna transcripts verified by real-time pcr Brain Research  2004 1000:211-222  DOI:10.1016/j.brainres.2003.11.069  PMID:15053970
• Reilly, J. F., Games, D., Rydel, R. E., Freedman, S., Schenk, D., Young, W. G., Morrison, J. H., Bloom, F. E. Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model Proceedings of the National Academy of Sciences of the United States of America  2003 100:4837-4842  DOI:10.1073/pnas.0330745100  PMID:12697936  PMCID:PMC153642
• Redwine, J. M., Kosofsky, B., Jacobs, R. E., Games, D., Reilly, J. F., Morrison, J. H., Young, W. G., Bloom, F. E. Dentate gyrus volume is reduced before onset of plaque formation in pdapp mice: A magnetic resonance microscopy and stereologic analysis Proceedings of the National Academy of Sciences of the United States of America  2003 100:1381-1386  DOI:10.1073/pnas.242746599  PMID:12552120  PMCID:PMC298781
• Hokfelt, T., Bartfai, T., Bloom, F. Neuropeptides: Opportunities for drug discovery Lancet Neurology  2003 2:463-472  DOI:10.1016/s1474-4422(03)00482-4  PMID:12878434
• Sanna, P. P., Cammalleri, M., Berton, F., Simpson, C., Lutjens, R., Bloom, F. E., Francesconi, W. Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region Journal of Neuroscience  2002 22:3359-3365  PMID:11978812
• Sanna, P. P., Berton, F., Cammalleri, M., Tallent, M. K., Siggins, G. R., Bloom, F. E., Francesconi, W. A role for Src kinase in spontaneous epileptiform activity in the CA3 region of the hippocampus Proceedings of the National Academy of Sciences of the United States of America  2000 97:8653-8657  DOI:10.1073/pnas.140219097  PMID:10890901  PMCID:PMC27003
• Nimchinsky, E. A., Young, W. G., Yeung, G., Shah, R. A., Gordon, J. W., Bloom, F. E., Morrison, J. H., Hof, P. R. Differential vulnerability of oculomotor, facial, and hypoglossal nuclei in g86r superoxide dismutase transgenic mice Journal of Comparative Neurology  2000 416:112-125  DOI:10.1002/(sici)1096-9861(20000103)416:1<112::aid-cne9>3.0.co;2-k  PMID:10578106
• Bloom, F. E. Publishing (whatever that means) neuroscience in the new millennium Brain Research  2000 886:1-4  DOI:10.1016/s0006-8993(00)02754-2  PMID:11119682
• Rende, M., Morales, M., Brizi, E., Bruno, R., Bloom, F., Sanna, P. P. Modulation of serotonin 5-HT3 receptor expression in injured adult rat spinal cord motoneurons Brain Research  1999 823:234-240  DOI:10.1016/s0006-8993(99)01180-4  PMID:10095035
• Polich, J., Bloom, F. E. P300, alcoholism heritability, and stimulus modality Alcohol  1999 17:149-156  DOI:10.1016/s0741-8329(98)00047-0  PMID:10064383
• Weed, M. R., Taffe, M. A., Polis, I., Roberts, A. C., Robbins, T. W., Koob, G. F., Bloom, F. E., Gold, L. H. Performance norms for a rhesus monkey neuropsychological testing battery: acquisition and long-term performance Cognitive Brain Research  1999 8:185-201  DOI:10.1016/s0926-6410(99)00020-8  PMID:10556598
• Morales, M., Criado, J. R., Sanna, P. P., Henriksen, S. J., Bloom, F. E. Acute ethanol induces c-fos immunoreactivity in GABAergic neurons of the central nucleus of the amygdala Brain Research  1998 798:333-336  DOI:10.1016/s0006-8993(98)00457-0  PMID:9666163
• Morales, R., Battenberg, E., Bloom, F. E. Distribution of neurons expressing immunoreactivity for the 5ht(3) receptor subtype in the rat brain and spinal cord Journal of Comparative Neurology  1998 402:385-401  PMID:9853906
• Yu, N. C., Zhang, X. H., Magistretti, P. J., Bloom, F. E. Il-1-alpha and tnf-alpha differentially regulate cd4 and mac-1 expression in mouse microglia Neuroimmunomodulation  1998 5:42-52  DOI:10.1159/000026325  PMID:9698257
• Raber, J., Sorg, O., Horn, T. F. W., Yu, N., Koob, G. F., Campbell, I. L., Bloom, F. E. Inflammatory cytokines: Putative regulators of neuronal and neuro-endocrine function Brain Research Reviews  1998 26:320-326  DOI:10.1016/s0165-0173(97)00041-6  PMID:9651548
• Burton, F. H., Forss-Petter, S., Battenberg, E., Bloom, F. E., Sutcliffe, J. G. Lethal psychomotor abnormalities in mice caused by a neural cholera toxin transgene Transgenics  1998 2:249-257
• Gold, L. H., Fox, H. S., Henriksen, S. J., Buchmeier, M. J., Weed, M. R., Taffe, M. A., Huitron-Resendiz, S., Horn, T. F. W., Bloom, F. E. Longitudinal analysis of behavioral, neurophysiological, viral and immunological effects of SIV infection in rhesus monkeys Journal of Medical Primatology  1998 27:104-112  DOI:10.1111/j.1600-0684.1998.tb00234.x  PMID:9747951
• Woldorff, M. G., Hillyard, S. A., Gallen, C. C., Hampson, S. R., Bloom, F. E. Magnetoencephalographic recordings demonstrate attentional modulation of mismatch-related neural activity in human auditory cortex Psychophysiology  1998 35:283-292  DOI:10.1017/s0048577298961601  PMID:9564748
• Koob, G. F., Sanna, P. P., Bloom, F. E. Neuroscience of addiction Neuron  1998 21:467-476  DOI:10.1016/s0896-6273(00)80557-7  PMID:9768834
• Begleiter, H., Porjesz, B., Reich, T., Edenberg, H. J., Goate, A., Blangero, J., Almasy, L., Foroud, T., Van Eerdewegh, P., Polich, J., Rohrbaugh, J., Kuperman, S., et al. Quantitative trait loci analysis of human event-related brain potentials: P3 voltage Evoked Potentials-Electroencephalography and Clinical Neurophysiology  1998 108:244-250  DOI:10.1016/s0168-5597(98)00002-1
• Trembleau, A., Bloom, F. E. Subcellular localization of tyrosine hydroxylase (th) gene transcripts: New insights into the pattern of th gene expression in the locus coeruleus under pharmacological stimulation Biology of the Cell  1998 90:39-51  DOI:10.1016/s0248-4900(98)80231-1  PMID:9691425
• Bloom, F. E., Morales, M. The central 5-ht3 receptor in cns disorders Neurochemical Research  1998 23:653-659  DOI:10.1023/a:1022486705184  PMID:9566603
• De Lecea, L., Kilduff, T. S., Peyron, C., Gao, X. B., Foye, P. E., Danielson, P. E., Fukuhara, C., Battenberg, E. L. F., Gautvik, V. T., Bartlett, F. S., Frankel, W. N., van den Pol, A. N., et al. The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity Proceedings of the National Academy of Sciences of the United States of America  1998 95:322-327  DOI:10.1073/pnas.95.1.322  PMID:9419374
• Akwa, Y., Hassett, D. E., Eloranta, M. L., Sandberg, K., Masliah, E., Powell, H., Whitton, J. L., Bloom, F. E., Campbell, I. L. Transgenic expression of ifn-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration Journal of Immunology  1998 161:5016-5026  PMID:9794439
• Raber, J., Mehta, P. P., Kreifeldt, M., Parsons, L. H., Weiss, F., Bloom, F. E., Wilson, M. C. Coloboma hyperactive mutant mice exhibit regional and transmitter-specific deficits in neurotransmission Journal of Neurochemistry  1997 68:176-186  DOI:10.1046/j.1471-4159.1997.68010176.x  PMID:8978724
• Jacobson, S., Henriksen, S. J., ProsperoGarcia, O., Phillips, T. R., Elder, J. H., Young, W. G., Bloom, F. E., Fox, H. S. Cortical neuronal cytoskeletal changes associated with fiv infection Journal of Neurovirology  1997 3:283-289  PMID:9291236
• Ryabinin, A. E., Criado, J. R., Henriksen, S. J., Bloom, F. E., Wilson, M. C. Differential sensitivity of c-fos expression in hippocampus and other brain regions to moderate and low doses of alcohol Molecular Psychiatry  1997 2:32-43  DOI:10.1038/sj.mp.4000206  PMID:9154216
• Cunningham, E. T., Stalder, A. K., Sanna, P. P., Liu, S. S., Bloom, F. E., Howes, E. L., Campbell, I. L., Margolis, T. P. Distribution of tumor necrosis factor receptor messenger rna in normal and herpes simplex virus infected trigeminal ganglia in the mouse Brain Research  1997 758:99-106  DOI:10.1016/s0006-8993(97)00169-8  PMID:9203538
• Sorg, O., Horn, T. F. W., Yu, N. C., Gruol, D. L., Bloom, F. E. Inhibition of astrocyte glutamate uptake by reactive oxygen species: Role of antioxidant enzymes Molecular Medicine  1997 3:431-440  PMID:9260155  PMCID:PMC2230215
• Raber, J., Koob, G. F., Bloom, F. E. Interferon-alpha and transforming growth factor-beta(1) regulate corticotropin-releasing factor release from the amygdala: Comparison with the hypothalamic response Neurochemistry International  1997 30:455-463  DOI:10.1016/s0197-0186(96)00082-4  PMID:9106261
• Stalder, A. K., Pagenstecher, A., Yu, N. C., Kincaid, C., Chiang, C. S., Hobbs, M. V., Bloom, F. E., Campbell, I. L. Lipopolysaccharide-induced il-12 expression in the central nervous system and cultured astrocytes and microglia Journal of Immunology  1997 159:1344-1351  PMID:9233631
• Cunningham, E. T., Stalder, A., Sanna, P. P., Liu, S. S., Bloom, F. E., Howes, E. L., Campbell, I. L., Margolis, T. P. Localization of tumor necrosis factor receptor messenger rna in normal and herpes simplex virus infected mouse eyes Investigative Ophthalmology & Visual Science  1997 38:9-15  PMID:9008625
• Gallen, C. C., Tecoma, E., Iragui, V., Sobel, D. F., Schwartz, B. J., Bloom, F. E. Magnetic source imaging of abnormal low-frequency magnetic activity in presurgical evaluations of epilepsy Epilepsia  1997 38:452-460  DOI:10.1111/j.1528-1157.1997.tb01735.x  PMID:9118851
• Raber, J., Oshea, R. D., Bloom, F. E., Campbell, I. L. Modulation of hypothalamic-pituitary-adrenal function by transgenic expression of interleukin-6 in the cns of mice Journal of Neuroscience  1997 17:9473-9480  PMID:9391003
• Fox, H. S., Gold, L. H., Henriksen, S. J., Bloom, F. E. Simian immunodeficiency virus: A model for neuroaids Neurobiology of Disease  1997 4:265-274  DOI:10.1006/nbdi.1997.0159  PMID:9361303
• Morales, M., Bloom, F. E. The 5-HT(3) receptor is present in different subpopulations of GABAergic neurons in the rat telencephalon Journal of Neuroscience  1997 17:3157-3167  PMID:9096150
• Bloom, F. E. An internet review: The compleat neuroscientist scours the world wide web Science  1996 274:1104-1108  DOI:10.1126/science.274.5290.1104  PMID:8895452
• Raber, J., Bloom, F. E. Arginine vasopressin release by acetylcholine or norepinephrine: Region-specific and cytokine-specific regulation Neuroscience  1996 71:747-759  DOI:10.1016/0306-4522(95)00517-x  PMID:8867047
• Morales, M., Battenberg, E., deLecea, L., Sanna, P. P., Bloom, F. E. Cellular and subcellular immunolocalization of the type 3 serotonin receptor in the rat central nervous system Molecular Brain Research  1996 36:251-260  DOI:10.1016/0169-328x(96)88406-3  PMID:8965645
• Trembleau, A., Morales, M., Bloom, F. E. Differential compartmentalization of vasopressin messenger rna and neuropeptide within the rat hypothalamo-neurohypophysial axonal tracts: Light and electron microscopic evidence Neuroscience  1996 70:113-125  DOI:10.1016/0306-4522(95)00328-g  PMID:8848117
• Weiss, F., Parsons, L. H., Schulteis, G., Hyytia, P., Lorang, M. T., Bloom, F. E., Koob, G. F. Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats Journal of Neuroscience  1996 16:3474-3485  PMID:8627380
• Mathiasen, J. R., MaciejewskiLenoir, D., Bloom, F. E., Sladek, C. D. Increased vasopressin secretion from hypothalamic cultures following administration of exogenous vasopressin mrna Experimental Neurology  1996 141:165-172  DOI:10.1006/exnr.1996.0150  PMID:8812149
• Heinrichs, S. C., StenzelPoore, M. P., Gold, L. H., Battenberg, E., Bloom, F. E., Koob, G. F., Vale, W. W., Pich, E. M. Learning impairment in transgenic mice with central overexpression of corticotropin-releasing factor Neuroscience  1996 74:303-311  DOI:10.1016/0306-4522(96)00140-6  PMID:8865183
• ProsperoGarcia, O., Gold, L. H., Fox, H. S., Polis, I., Koob, G. F., Bloom, F. E., Henriksen, S. J. Microglia-passaged simian immunodeficiency virus induces neurophysiological abnormalities in monkeys Proceedings of the National Academy of Sciences of the United States of America  1996 93:14158-14163  DOI:10.1073/pnas.93.24.14158  PMID:8943077
• Phillips, T. R., ProsperoGarcia, O., Wheeler, D. W., Wagaman, P. C., Lerner, D. L., Fox, H. S., Whalen, L. R., Bloom, F. E., Elder, J. H., Henriksen, S. J. Neurologic dysfunctions caused by a molecular clone of feline immunodeficiency virus, fiv-ppr Journal of Neurovirology  1996 2:388-396  DOI:10.3109/13550289609146904  PMID:8972420
• Easton, C., Bauer, L. O., Begleiter, H., Reich, T., Nurnberger, J., Conneally, P. M., Crow, R., Kuperman, S., Schuckit, M., Bloom, F. E., Hesselbrock, V., Porjesz, B., et al. Neuropsychological correlates of urine toxicology results Progress in Neuro-Psychopharmacology & Biological Psychiatry  1996 20:969-982  DOI:10.1016/0278-5846(96)00077-2  PMID:8888104
• Gautvik, K. M., deLecea, L., Gautvik, V. T., Danielson, P. E., Tranque, P., Dopazo, A., Bloom, F. E., Sutcliffe, J. G. Overview of the most prevalent hypothalamus-specific mrnas, as identified by directional tag pcr subtraction Proceedings of the National Academy of Sciences of the United States of America  1996 93:8733-8738  DOI:10.1073/pnas.93.16.8733  PMID:8710940
• Sanna, P. P., deLogu, A., Williamson, R. A., Hom, Y. L., Straus, S. E., Bloom, F. E., Burton, D. R. Protection of nude mice by passive immunization with a type-common human recombinant monoclonal antibody against hsv Virology  1996 215:101-106  DOI:10.1006/viro.1996.0011  PMID:8553581
• Trembleau, A., Bloom, F. E. Spatial segregation of g(alpha s) mrna and vasopressin mrna to distinct domains of the rough endoplasmic reticulum within secretory neurons of the rat hypothalamus Molecular and Cellular Neuroscience  1996 7:17-28  DOI:10.1006/mcne.1996.0002  PMID:8812056
• Bloom, F. E. The multidimensional database and neuroinformatics requirements for molecular and cellular neuroscience Neuroimage  1996 4:S12-S13  DOI:10.1006/nimg.1996.0042  PMID:9345517
• Morales, M., Battenberg, E., deLecea, L., Bloom, F. E. The type 3 serotonin receptor is expressed in a subpopulation of gabaergic neurons in the rat neocortex and hippocampus Brain Research  1996 731:199-202  DOI:10.1016/s0006-8993(96)00557-4  PMID:8883870
• Ryabinin, A. E., Melia, K. R., Cole, M., Bloom, F. E., Wilson, M. C. Alcohol selectively attenuates stress-induced c-fos expression in rat hippocampus Journal of Neuroscience  1995 15:721-730  PMID:7823175
• Trembleau, A., Melia, K. R., Bloom, F. E. Bc1 rna and vasopressin messenger-rna in rat neurohypophysis - axonal compartmentalization and differential regulation during dehydration and rehydration European Journal of Neuroscience  1995 7:2249-2260  DOI:10.1111/j.1460-9568.1995.tb00646.x  PMID:8563974
• Geiger, K. D., Gurushanthaiah, D., Howes, E. L., Lewandowski, G. A., Reed, J. C., Bloom, F. E., Sarvetnick, N. E. Cytokine-mediated survival from lethal herpes-simplex virus-infection - role of programmed neuronal death Proceedings of the National Academy of Sciences of the United States of America  1995 92:3411-3415  DOI:10.1073/pnas.92.8.3411  PMID:7724576
• Sanna, P. P., Williamson, R. A., Delogu, A., Bloom, F. E., Burton, D. R. Directed selection of recombinant human monoclonal-antibodies to herpes-simplex virus glycoproteins from phage display libraries Proceedings of the National Academy of Sciences of the United States of America  1995 92:6439-6443  DOI:10.1073/pnas.92.14.6439  PMID:7604009
• Trembleau, A., Bloom, F. E. Enhanced sensitivity for light and electron-microscopic in-situ hybridization with multiple simultaneous nonradioactive oligodeoxynucleotide probes Journal of Histochemistry & Cytochemistry  1995 43:829-841  PMID:7622844
• Ryabinin, A. E., Cole, M., Bloom, F. E., Wilson, M. C. Exposure of neonatal rats to alcohol by vapor inhalation demonstrates specificity of microcephaly and purkinje-cell loss but not astrogliosis Alcoholism-Clinical and Experimental Research  1995 19:784-791  DOI:10.1111/j.1530-0277.1995.tb01583.x  PMID:7573809
• Henriksen, S. J., Prospero-Garcia, O., Phillips, T. R., Fox, H. S., Bloom, F. E., Elder, J. H. Feline immunodeficiency virus as a model for study of lentivirus infection of the central nervous system Current Topics in Microbiology and Immunology  1995 202:167-186  PMID:7587362
• Bloom, F. E. Gene-expression from recombinant viral vectors in the central-nervous-system after blood-brain-barrier disruption - comment Neurosurgery  1995 36:970-970
• Lerner, D. L., Wagaman, P. C., Phillips, T. R., Prosperogarcia, O., Henriksen, S. J., Fox, H. S., Bloom, F. E., Elder, J. H. Increased mutation frequency of feline immunodeficiency virus lacking functional deoxyuridine-triphosphatase Proceedings of the National Academy of Sciences of the United States of America  1995 92:7480-7484  DOI:10.1073/pnas.92.16.7480  PMID:7638216
• Raber, J., Koob, G. F., Bloom, F. E. Interleukin-2 (il-2) induces corticotropin-releasing factor (crf) release from the amygdala and involves a nitric oxide-mediated signaling - comparison with the hypothalamic response Journal of Pharmacology and Experimental Therapeutics  1995 272:815-824  PMID:7853199
• Bloom, F. E. Neuroscience knowledge management - slow change so far Trends in Neurosciences  1995 18:48-49  DOI:10.1016/0166-2236(95)93864-t  PMID:7537402
• Sanna, P. P., Delogu, A., Williamson, R. A., Samson, M. E., Altieri, D. C., Bloom, F. E., Burton, D. R. Rapid assay of phage-derived recombinant human Fabs as bispecific antibodies Bio-Technology  1995 13:1221-1224  DOI:10.1038/nbt1195-1221  PMID:9636296
• Sanna, P. P., Weiss, F., Samson, M. E., Bloom, F. E., Pich, E. M. Rapid induction of tumor-necrosis-factor-alpha in the cerebrospinal-fluid after intracerebroventricular injection of lipopolysaccharide revealed by a sensitive capture immuno-pcb assay Proceedings of the National Academy of Sciences of the United States of America  1995 92:272-275  DOI:10.1073/pnas.92.1.272  PMID:7816831
• Yu, N. C., Maciejewskilenoir, D., Bloom, F. E., Magistretti, P. J. Tumor-necrosis-factor-alpha and interleukin-1-alpha enhance glucose-utilization by astrocytes - involvement of phospholipase a(2) Molecular Pharmacology  1995 48:550-558  PMID:7565637
• Godbout, M., Erlander, M. G., Hasel, K. W., Danielson, P. E., Wong, K. K., Battenberg, E. L. F., Foye, P. E., Bloom, F. E., Sutcliffe, J. G. 1G5: a calmodulin-binding, vesicle-associated, protein kinase-like protein enriched in forebrain neurites Journal of Neuroscience  1994 14:1-13  PMID:8283228
• Trembleau, A., Morales, M., Bloom, F. E. Aggregation of vasopressin messenger-rna in a subset of axonal swellings of the median-eminence and posterior pituitary - light and electron-microscopic evidence Journal of Neuroscience  1994 14:39-53  PMID:8283246
• Lewandowski, G., Hobbs, M. V., Bloom, F. E. Alteration of intracerebral cytokine production in mice infected with herpes-simplex virus type-1 and type-2 Journal of Neuroimmunology  1994 55:23-34  DOI:10.1016/0165-5728(94)90143-0  PMID:7962482
• Melia, K. R., Trembleau, A., Oddi, R., Sanna, P. P., Bloom, F. E. Detection and regulation of tyrosine-hydroxylase messenger-rna in catecholaminergic terminal fields - possible axonal compartmentalization Experimental Neurology  1994 130:394-406  DOI:10.1006/exnr.1994.1219  PMID:7532593
• Danielson, P. E., Forsspetter, S., Battenberg, E. L. F., Delecea, L., Bloom, F. E., Sutcliffe, J. G. Four structurally distinct neuron-specific olfactomedin-related glycoproteins produced by differential promoter utilization and alternative mRNA splicing from a single gene Journal of Neuroscience Research  1994 38:468-478  DOI:10.1002/jnr.490380413  PMID:7932877
• Raber, J., Pich, E. M., Koob, G. F., Bloom, F. E. Il-1-beta potentiates the acetylcholine-induced release of vasopressin from the hypothalamus in-vitro, but not from the amygdala Neuroendocrinology  1994 59:208-217  DOI:10.1159/000126661  PMID:8159270
• Raber, J., Bloom, F. E. Il-2 induces vasopressin release from the hypothalamus and the amygdala - role of nitric oxide-mediated signaling Journal of Neuroscience  1994 14:6187-6195  PMID:7523633
• Melia, K. R., Ryabinin, A. E., Schroeder, R., Bloom, F. E., Wilson, M. C. Induction and habituation of immediate-early gene-expression in rat-brain by acute and repeated restraint stress Journal of Neuroscience  1994 14:5929-5938  PMID:7931554
• Gallen, C. C., Schwartz, B., Rieke, K., Pantev, C., Sobel, D., Hirschkoff, E., Bloom, F. E. Intrasubject reliability and validity of somatosensory source localization using a large array biomagnetometer Electroencephalography and Clinical Neurophysiology  1994 90:145-156  DOI:10.1016/0013-4694(94)90006-x  PMID:7510629
• Polich, J., Pollock, V. E., Bloom, F. E. Metaanalysis of p300 amplitude from males at risk for alcoholism Psychological Bulletin  1994 115:55-73  DOI:10.1037//0033-2909.115.1.55  PMID:8310100
• Phillips, T. R., Prosperogarcia, O., Puaoi, D. L., Lerner, D. L., Fox, H. S., Olmsted, R. A., Bloom, F. E., Henriksen, S. J., Elder, J. H. Neurological abnormalities associated with feline immunodeficiency virus-infection Journal of General Virology  1994 75:979-987  DOI:10.1099/0022-1317-75-5-979  PMID:8176384
• Bloom, F. E., Young, W. G. New solutions for neuroscience communications are still needed Neuroscience: From the Molecular to the Cognitive  1994 100:275-281  PMID:7938529
• Yang, T. T., Gallen, C. C., Ramachandran, V. S., Cobb, S., Schwartz, B. J., Bloom, F. E. Noninvasive detection of cerebral plasticity in adult human somatosensory cortex Neuroreport  1994 5:701-704  DOI:10.1097/00001756-199402000-00010  PMID:8199341
• Alexander, J. E., Polich, J., Bloom, F. E., Bauer, L. O., Kuperman, S., Rohrbaugh, J., Morzorati, S., Oconnor, S. J., Porjesz, B., Begleiter, H. P300 from an auditory oddball task - inter-laboratory consistency International Journal of Psychophysiology  1994 17:35-46  DOI:10.1016/0167-8760(94)90053-1  PMID:7961052
• Burioni, R., Williamson, R. A., Sanna, P. P., Bloom, F. E., Burton, D. R. Recombinant human fab to glycoprotein-d neutralizes infectivity and prevents cell-to-cell transmission of herpes-simplex virus-1 and virus-2 in-vitro Proceedings of the National Academy of Sciences of the United States of America  1994 91:355-359  DOI:10.1073/pnas.91.1.355  PMID:8278393
• Prosperogarcia, O., Herold, N., Phillips, T. R., Elder, J. H., Bloom, F. E., Henriksen, S. J. Sleep patterns are disturbed in cats infected with feline immunodeficiency virus Proceedings of the National Academy of Sciences of the United States of America  1994 91:12947-12951  DOI:10.1073/pnas.91.26.12947  PMID:7809152
• Bloom, F. E. Advancing a neurodevelopmental origin for schizophrenia Archives of General Psychiatry  1993 50:224-227  PMID:8439244
• Gallen, C. C., Bloom, F. E. Brain imaging - mapping the brain with msi Current Biology  1993 3:522-524  DOI:10.1016/0960-9822(93)90046-q  PMID:15335693
• Sanna, P. P., Folsom, D. P., Barizo, M. J., Hirsch, M. D., Melia, K. R., Maciejewskilenoir, D., Bloom, F. E. Chronic ethanol intake decreases vasopressin messenger-rna content in the rat hypothalamus - a pcr study Molecular Brain Research  1993 19:241-245  DOI:10.1016/0169-328x(93)90035-n  PMID:8412569
• Sanna, P. P., Keyser, K. T., Celio, M. R., Karten, H. J., Bloom, F. E. Distribution of parvalbumin immunoreactivity in the vertebrate retina Brain Research  1993 600:141-150  DOI:10.1016/0006-8993(93)90412-g  PMID:8422581
• Moses, A. V., Bloom, F. E., Pauza, C. D., Nelson, J. A. Human-immunodeficiency-virus infection of human brain capillary endothelial-cells occurs via a cd4 galactosylceramide-independent mechanism Proceedings of the National Academy of Sciences of the United States of America  1993 90:10474-10478  DOI:10.1073/pnas.90.22.10474  PMID:7504264
• Lewandowski, G. A., Lo, D., Bloom, F. E. Interference with major histocompatibility complex class-ii-restricted antigen presentation in the brain by herpes-simplex virus type-1 - a possible mechanism of evasion of the immune-response Proceedings of the National Academy of Sciences of the United States of America  1993 90:2005-2009  DOI:10.1073/pnas.90.5.2005  PMID:8095338
• Sobel, D. F., Gallen, C. C., Schwartz, B. J., Waltz, T. A., Copeland, B., Yamada, S., Hirschkoff, E. C., Bloom, F. E. Locating the central sulcus - comparison of mr anatomic and magnetoencephalographic functional methods American Journal of Neuroradiology  1993 14:915-925  PMID:8352165
• Woldorff, M. G., Gallen, C. C., Hampson, S. A., Hillyard, S. A., Pantev, C., Sobel, D., Bloom, F. E. Modulation of early sensory processing in human auditory-cortex during auditory selective attention Proceedings of the National Academy of Sciences of the United States of America  1993 90:8722-8726  DOI:10.1073/pnas.90.18.8722  PMID:8378354
• Gallen, C. C., Roberts, D. W., Sobel, D. F., Waltz, T., Crandall, P. H., Aung, M., Copeland, B., Schwartz, B. J., Hirschkoff, E. C., Bloom, F. E. Noninvasive presurgical neuromagnetic mapping of somatosensory cortex Neurosurgery  1993 33:260-268  PMID:8367048
• Yang, T. T., Gallen, C. C., Schwartz, B. J., Bloom, F. E. Noninvasive somatosensory homunculus mapping in humans by using a large-array biomagnetometer Proceedings of the National Academy of Sciences of the United States of America  1993 90:3098-3102  DOI:10.1073/pnas.90.7.3098  PMID:8464929
• Weiss, F., Lorang, M. T., Bloom, F. E., Koob, G. F. Oral alcohol self-administration stimulates dopamine release in the rat nucleus-accumbens - genetic and motivational determinants Journal of Pharmacology and Experimental Therapeutics  1993 267:250-258  PMID:8229752
• Sanna, P. P., Celio, M. R., Bloom, F. E., Rende, M. Presumptive renshaw cells contain decreased calbindin during recovery from sciatic-nerve lesions Proceedings of the National Academy of Sciences of the United States of America  1993 90:3048-3052  DOI:10.1073/pnas.90.7.3048  PMID:8464922
• Maciejewskilenoir, D., Jirikowski, G. F., Sanna, P. P., Bloom, F. E. Reduction of exogenous vasopressin rna poly(a) tail length increases its effectiveness in transiently correcting diabetes-insipidus in the brattleboro rat Proceedings of the National Academy of Sciences of the United States of America  1993 90:1435-1439  DOI:10.1073/pnas.90.4.1435  PMID:7679506
• Bloom, F. E., Engel, J. Aberrant genetic expression and opportunities for epilepsy research Epilepsy Research  1992 1-18
• Sanna, P. P., Jirikowski, G. F., Lewandowski, G. A., Bloom, F. E. Applications of dapi cytochemistry to neurobiology Biotechnic & Histochemistry  1992 67:346-350  DOI:10.3109/10520299209110047  PMID:1489836
• Giovannelli, L., Bloom, F. E. C-fos protein expression in the rat subfornical organ following osmotic stimulation Neuroscience Letters  1992 139:1-6  DOI:10.1016/0304-3940(92)90844-w  PMID:1407673
• Shiromani, P. J., Kilduff, T. S., Bloom, F. E., McCarley, R. W. Cholinergically induced rem-sleep triggers fos-like immunoreactivity in dorsolateral pontine regions associated with rem-sleep Brain Research  1992 580:351-357  DOI:10.1016/0006-8993(92)90968-f  PMID:1504815
• Sanna, P. P., Keyser, K. T., Deerink, T. J., Ellisman, M. H., Karten, H. J., Bloom, F. E. Distribution and ontogeny of parvalbumin immunoreactivity in the chicken retina Neuroscience  1992 47:745-751  DOI:10.1016/0306-4522(92)90182-2  PMID:1584416
• Giovannelli, L., Shiromani, P. J., Jirikowski, G. F., Bloom, F. E. Expression of c-fos protein by immunohistochemically identified oxytocin neurons in the rat hypothalamus upon osmotic stimulation Brain Research  1992 588:41-48  DOI:10.1016/0006-8993(92)91342-c  PMID:1393570
• Sanna, P. P., Jirikowski, G. F., Maciejewskilenoir, D., Bloom, F. E. Expression of exogenous vasopressin messenger-rna by magnocellular neurons of the supraoptic and paraventricular nuclei in brattleboro rats Annals of the New York Academy of Sciences  1992 652:462-465  DOI:10.1111/j.1749-6632.1992.tb34385.x  PMID:1626850
• Jirikowski, G. F., Sanna, P. P., Maciejewskilenoir, D., Bloom, F. E. Reversal of diabetes-insipidus in brattleboro rats - intrahypothalamic injection of vasopressin messenger-rna Science  1992 255:996-998  DOI:10.1126/science.1546298  PMID:1546298
• Bloom, F. E. Training neuroscientists for the 21st-century Trends in Neurosciences  1992 15:383-386  DOI:10.1016/0166-2236(92)90184-a  PMID:1279859
• Sanna, P. P., Bloom, F. E., Wilson, M. C. Dibutyryl-camp induces snap-25 translocation into the neurites in pc12 Developmental Brain Research  1991 59:104-108  DOI:10.1016/0165-3806(91)90035-h  PMID:1645626
• Sutcliffe, J. G., Travis, G. H., Danielson, P. E., Wong, K. K., Ottiger, H. P., Burton, F. H., Hasel, K. W., Bloom, F. E., Forsspetter, S. Molecular approaches to genes of the cns Epilepsy Research  1991 213-223
• Bloom, F. E. Molecular studies in neuroscience - implications for medicine Biological Chemistry Hoppe-Seyler  1991 372:245-254  PMID:1676270
• Burton, F. H., Hasel, K. W., Bloom, F. E., Sutcliffe, J. G. Pituitary hyperplasia and gigantism in mice caused by a cholera toxin transgene Nature  1991 350:74-77  DOI:10.1038/350074a0  PMID:1848356
• Ottiger, H. P., Battenberg, E. F., Tsou, A. P., Bloom, F. E., Sutcliffe, J. G. 1B1075: a brain- and pituitary-specific mRNA that encodes a novel chromogranin/secretogranin-like component of intracellular vesicles Journal of Neuroscience  1990 10:3135-3147  PMID:2204688
• Weiss, F., Mitchiner, M., Bloom, F. E., Koob, G. F. Free-choice responding for ethanol versus water in alcohol preferring (p) and unselected wistar rats is differentially modified by naloxone, bromocriptine, and methysergide Psychopharmacology  1990 101:178-186  DOI:10.1007/bf02244123  PMID:2349359
• Bloom, F. E., Bulger, R. E., Randolph, M. A. Funding health-sciences research - a strategy to restore balance Clinical Research  1990 38:671-685  PMID:2177388
• Sussman, M. A., Battenberg, E., Bloom, F. E., Fowler, V. M. Identification of two nerve growth factor-induced polypeptides in PC12 cells Journal of Molecular Neuroscience  1990 2:163-174  DOI:10.1007/bf02896841  PMID:2275847
• Jirikowski, G. F., Ramalhoortigao, J. F., Kesse, K. W., Bloom, F. E. Insitu hybridization of semithin epon sections with brdu labeled oligonucleotide probes Histochemistry  1990 94:187-190  DOI:10.1007/bf02440186  PMID:2358376
• Jirikowski, G. F., Sanna, P. P., Bloom, F. E. Messenger-rna coding for oxytocin is present in axons of the hypothalamoneurohypophyseal tract Proceedings of the National Academy of Sciences of the United States of America  1990 87:7400-7404  DOI:10.1073/pnas.87.19.7400  PMID:2268384
• Giovannelli, L., Shiromani, P. J., Jirikowski, G. F., Bloom, F. E. Oxytocin neurons in the rat hypothalamus exhibit c-fos immunoreactivity upon osmotic-stress Brain Research  1990 531:299-303  DOI:10.1016/0006-8993(90)90789-e  PMID:2126973
• Polich, J., Ladish, C., Bloom, F. E. P300 assessment of early alzheimers-disease Electroencephalography and Clinical Neurophysiology  1990 77:179-189  DOI:10.1016/0168-5597(90)90036-d  PMID:1691970
• Sanna, P. P., Keyser, K. T., Battenberg, E., Bloom, F. E. Parvalbumin immunoreactivity in the rat retina Neuroscience Letters  1990 118:136-139  DOI:10.1016/0304-3940(90)90267-d  PMID:2259462
• Watson, J. B., Battenberg, E. F., Wong, K. K., Bloom, F. E., Sutcliffe, J. G. Subtractive cdna cloning of rc3, a rodent cortex-enriched messenger-rna encoding a novel 78 residue protein Journal of Neuroscience Research  1990 26:397-408  DOI:10.1002/jnr.490260402  PMID:2231781
• Bloom, F. E., Higgins, G. A., Schmale, H., Wilson, M. C. Cellular-localization of 1b236/myelin-associated glycoprotein messenger-rna during rat-brain development Proceedings of the National Academy of Sciences of the United States of America  1989 86:2074-2078  DOI:10.1073/pnas.86.6.2074  PMID:2467299
• Forsspetter, S., Danielson, P., Battenberg, E., Bloom, F., Sutcliffe, J. G. Nucleotide-sequence and cellular-distribution of rat chromogranin-b (secretogranin-i) messenger-rna in the neuro-endocrine system Journal of Molecular Neuroscience  1989 1:63-75  DOI:10.1007/bf02918892  PMID:2641278
• Koob, G. F., Wall, T. L., Bloom, F. E. Nucleus accumbens as a substrate for the aversive stimulus effects of opiate withdrawal Psychopharmacology  1989 98:530-534  DOI:10.1007/bf00441954  PMID:2505294
• Koob, G. F., Stinus, L., Lemoal, M., Bloom, F. E. Opponent process theory of motivation - neurobiological evidence from studies of opiate dependence Neuroscience and Biobehavioral Reviews  1989 13:135-140  DOI:10.1016/s0149-7634(89)80022-3  PMID:2682399
• Bloom, F. E., Miller, F. D., Ozimek, G. Regulation of neuronal oxytocin messenger-rna by ovarian-steroids in the mature and developing hypothalamus Proceedings of the National Academy of Sciences of the United States of America  1989 86:2468-2472  DOI:10.1073/pnas.86.7.2468  PMID:2928343
• Oyler, G. A., Higgins, G. A., Hart, R. A., Battenberg, E., Billingsley, M., Bloom, F. E., Wilson, M. C. The identification of a novel synaptosomal-associated protein, snap-25, differentially expressed by neuronal subpopulations Journal of Cell Biology  1989 109:3039-3052  DOI:10.1083/jcb.109.6.3039  PMID:2592413
• Polich, J., Haier, R. J., Buchsbaum, M., Bloom, F. E. Assessment of young men at risk for alcoholism with p300 from a visual-discrimination task Journal of Studies on Alcohol  1988 49:186-190  PMID:3361911
• Mitler, M. M., Dawson, A., Henriksen, S. J., Sobers, M., Bloom, F. E. Bedtime ethanol increases resistance of upper airways and produces sleep apneas in asymptomatic snorers Alcoholism-Clinical and Experimental Research  1988 12:801-805  DOI:10.1111/j.1530-0277.1988.tb01349.x  PMID:3064641
• Koob, G. F., Bloom, F. E. Cellular and molecular mechanisms of drug-dependence Science  1988 242:715-723  DOI:10.1126/science.2903550  PMID:2903550
• Naus, C. C. G., Morrison, J. H., Bloom, F. E. Development of somatostatin-containing neurons and fibers in the rat hippocampus Developmental Brain Research  1988 40:113-121  DOI:10.1016/0165-3806(88)90013-2
• Polich, J., Bloom, F. E. Event-related brain potentials in individuals at high and low-risk for developing alcoholism - failure to replicate Alcoholism-Clinical and Experimental Research  1988 12:368-373  DOI:10.1111/j.1530-0277.1988.tb00210.x  PMID:3044165
• Naus, C. C. G., Bloom, F. E. Immunohistochemical analysis of the development of somatostatin in the reeler neocortex Developmental Brain Research  1988 43:61-68  DOI:10.1016/0165-3806(88)90153-8  PMID:2905929
• Naus, C. C. G., Miller, F. D., Morrison, J. H., Bloom, F. E. Immunohistochemical and insitu hybridization analysis of the development of the rat somatostatin-containing neocortical neuronal system Journal of Comparative Neurology  1988 269:448-463  DOI:10.1002/cne.902690311  PMID:2897381
• Bloom, F. E. Neurotransmitters - past, present, and future-directions FASEB Journal  1988 2:32-41  PMID:2891578
• Polich, J., Burns, T., Bloom, F. E. P300 and the risk for alcoholism - family history, task-difficulty, and gender Alcoholism-Clinical and Experimental Research  1988 12:248-254  DOI:10.1111/j.1530-0277.1988.tb00189.x  PMID:3287988
• Koob, G. F., Mendelson, W. B., Schafer, J., Wall, T. L., Britton, K. T., Bloom, F. E. Picrotoxinin receptor ligand blocks anti-punishment effects of alcohol Alcohol  1988 5:437-443  DOI:10.1016/0741-8329(88)90079-1  PMID:2854473
• Delima, A. D., Bloom, F. E., Morrison, J. H. Synaptic organization of serotonin-immunoreactive fibers in primary visual-cortex of the macaque monkey Journal of Comparative Neurology  1988 274:280-294  DOI:10.1002/cne.902740211  PMID:3209742
• Staunton, D. A., Svensson, T. H., Chouvet, G. E., Siggins, G. R., Bloom, F. E. Systemic phenoxybenzamine but not beta-adrenergic antagonists block noradrenergic inhibition of cerebellar purkinje and hippocampal pyramidal neurons Journal of Neural Transmission  1988 73:101-113  DOI:10.1007/bf01243381  PMID:2905380
• Lipkin, W. I., Battenberg, E. L. F., Bloom, F. E., Oldstone, M. B. A. Viral infection of neurons can depress neurotransmitter mRNA levels without histologic injury Brain Research  1988 451:333-339  DOI:10.1016/0006-8993(88)90779-2  PMID:2908027
• Bloom, F. E., Nave, K. A. A single nucleotide difference in the gene for myelin proteolipid protein defines the jimpy mutation in mouse Journal of Neurochemistry  1987 49:1873-1877  PMID:2445921
• Bloom, F. E., Sutcliffe, J. G. Brain-specific genes - strategies and issues Current Topics in Developmental Biology  1987 21:117-150  PMID:2443305
• Lewis, D. A., Bloom, F. E. Clinical perspectives on neuropeptides Annual Review of Medicine  1987 38:143-148  DOI:10.1146/annurev.med.38.1.143  PMID:2953298
• Bloom, F. E., Higgins, G. A., Miller, F. D., Naus, C. C. G. Developmentally regulated rat brain mRNAs: molecular and anatomical characterization Journal of Neuroscience  1987 7:2433-2444  PMID:2441010
• Bloom, F. E., Siggins, G. R. Electrophysiological action of ethanol at the cellular-level Alcohol  1987 4:331-337  DOI:10.1016/0741-8329(87)90031-0  PMID:3304331
• Siggins, G. R., Bloom, F. E., French, E. D., Madamba, S. G., Mancillas, J., Pittman, Q. J., Rogers, J. Electrophysiology of ethanol on central neurons Annals of the New York Academy of Sciences  1987 492:350-366  DOI:10.1111/j.1749-6632.1987.tb48692.x  PMID:3474932
• Wiesner, J. B., Henriksen, S. J., Bloom, F. E. Ethanol enhances recurrent inhibition in the dentate gyrus of the hippocampus Neuroscience Letters  1987 79:169-173  DOI:10.1016/0304-3940(87)90691-4  PMID:3670725
• McKinnon, R. D., Danielson, P., Brow, M. A. D., Bloom, F. E., Sutcliffe, J. G. Expression of small cytoplasmic transcripts of the rat identifier element in vivo and in cultured cells Molecular and Cellular Biology  1987 7:2148-2154  PMID:2439903  PMCID:PMC365337
• Lebrun, C., Lemoal, M., Dantzer, R., Bloom, F. E., Koob, G. F. Hypertonic saline mimics the effects of vasopressin on inhibitory avoidance in the rat Behavioral and Neural Biology  1987 47:130-137  DOI:10.1016/s0163-1047(87)90229-9  PMID:3579833
• Bloom, F. E. Hypothalamus: past, present, future Advances in Biochemical Psychopharmacology  1987 43:1-11  PMID:2884815
• Bloom, F. E., Durand, M., Miller, F. D., Naus, C. C. G. Isotypes of a-tubulin are differentially regulated during neuronal maturation Journal of Cell Biology  1987 105:3065-3073  DOI:10.1083/jcb.105.6.3065  PMID:3693406
• Bloom, F. E. Molecular diversity and cellular functions of neuropeptides Progress in Brain Research  1987 72:213-220  PMID:3039577
• Bloom, F. E., Lai, C., Sutcliffe, J. G., Watson, J. B. Neural protein 1B236/myelin-associated glycoprotein (MAG) defines a subgroup of the immunoglobulin superfamily Immunological Reviews  1987 100:129-151  DOI:10.1111/j.1600-065X.1987.tb00530.x  PMID:2450062
• Polich, J., Bloom, F. E. P300 from normals and adult children of alcoholics Alcohol  1987 4:301-305  DOI:10.1016/0741-8329(87)90027-9  PMID:3620099
• Bloom, F. E., Lai, C., Nave, K. A. Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin Proceedings of the National Academy of Sciences of the United States of America  1987 84:5665-5669  DOI:10.1073/pnas.84.16.5665  PMID:2441390
• Travis, G. H., Naus, C. G., Morrison, J. H., Bloom, F. E., Sutcliffe, J. G. Subtractive cloning of complementary dnas and analysis of messenger-rnas with regional heterogeneous distributions in primate cortex Neuropharmacology  1987 26:845-854  DOI:10.1016/0028-3908(87)90061-x  PMID:2443867
• Bloom, F. E., Brow, M. A., Lai, C., Nave, K. A., Noronha, A. B., Quarles, R. H., Sutcliffe, J. G. Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing Proceedings of the National Academy of Sciences of the United States of America  1987 84:4337-4341  DOI:10.1073/pnas.84.12.4337  PMID:2438699  PMCID:PMC305080
• Celio, M. R., Scharer, L., Morrison, J. H., Norman, A. W., Bloom, F. E. Calbindin immunoreactivity alternates with cytochrome-c-oxidase-rich zones in some layers of the primate visual-cortex Nature  1986 323:715-717  DOI:10.1038/323715a0  PMID:3022149
• Koob, G. F., Dantzer, R., Bluthe, R. M., Lebrun, C., Bloom, F. E., Lemoal, M. Central injections of arginine vasopressin prolong extinction of active-avoidance Peptides  1986 7:213-218  DOI:10.1016/0196-9781(86)90215-9  PMID:3737445
• Loughlin, S. E., Foote, S. L., Bloom, F. E. Efferent projections of nucleus locus-coeruleus - topographic organization of cells of origin demonstrated by 3-dimensional reconstruction Neuroscience  1986 18:291-306  DOI:10.1016/0306-4522(86)90155-7  PMID:3736860
• Bloom, F. E. Genetic background for multiple messengers Progress in Brain Research  1986 68:149-159  DOI:10.1016/s0079-6123(08)60236-8  PMID:3562850
• Bloom, F. E. Identifying neuropeptides by gene cloning Psychopharmacology Bulletin  1986 22:701-707  PMID:3797575
• Celio, M. R., Keller, G. A., Bloom, F. E. Immunoelectronmicroscopy of neural antigens on ultrathin frozen-sections Journal of Histochemistry & Cytochemistry  1986 34:491-500  PMID:3512699
• Bloom, F. E., Lai, C., Nave, K. A. Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing Proceedings of the National Academy of Sciences of the United States of America  1986 83:9264-9268  DOI:10.1073/pnas.83.23.9264  PMID:3466187
• Bloom, F. E. Molecular mechanisms of psychopathology Clinical Neuropharmacology  1986 9:1-2
• Chavkin, C., Bloom, F. E. Opiate antagonists do not alter neuronal responses to stimulation of opioid-containing pathways in rat hippocampus Neuropeptides  1986 7:19-22  DOI:10.1016/0143-4179(86)90074-0  PMID:2869440
• Wiesner, J. B., Henriksen, S. J., Bloom, F. E. Opioid enhancement of perforant path transmission - effect of an enkephalin analog on inhibition and facilitation in the dentate gyrus Brain Research  1986 399:404-408  DOI:10.1016/0006-8993(86)91537-4  PMID:3030491
• Polich, J., Bloom, F. E. P300 and alcohol-consumption in normals and individuals at risk for alcoholism - a preliminary-report Progress in Neuro-Psychopharmacology & Biological Psychiatry  1986 10:201-210  DOI:10.1016/0278-5846(86)90074-6  PMID:3749511
• Polich, J., Ehlers, C. L., Otis, S., Mandell, A. J., Bloom, F. E. P300 latency reflects the degree of cognitive decline in dementing illness Electroencephalography and Clinical Neurophysiology  1986 63:138-144  DOI:10.1016/0013-4694(86)90007-6  PMID:2417814
• Mancillas, J. R., Siggins, G. R., Bloom, F. E. Somatostatin selectively enhances acetylcholine-induced excitations in rat hippocampus and cortex Proceedings of the National Academy of Sciences of the United States of America  1986 83:7518-7521  DOI:10.1073/pnas.83.19.7518  PMID:2876428
• Deyo, S. N., Shoemaker, W. J., Ettenberg, A., Bloom, F. E., Koob, G. F. Subcutaneous administration of behaviorally effective doses of arginine vasopressin change brain avp content only in median-eminence Neuroendocrinology  1986 42:260-266  DOI:10.1159/000124449  PMID:3951675
• Mancillas, J. R., Siggins, G. R., Bloom, F. E. Systemic ethanol: selective enhancement of responses to acetylcholine and somatostatin in hippocampus Science  1986 231:161-163  DOI:10.1126/science.2867600  PMID:2867600
• Battenberg, E., Bloom, F. E., Kiel, M., Lenoir, D. The brain-specific gene 1B236 is expressed postnatally in the developing rat brain Journal of Neuroscience  1986 6:522-530  PMID:3950709
• Koob, G. F., Lebrun, C., Martinez, J. L., Dantzer, R., Lemoal, M., Bloom, F. E. Arginine vasopressin, stress, and memory Annals of the New York Academy of Sciences  1985 444:194-202  DOI:10.1111/j.1749-6632.1985.tb37589.x  PMID:3860087
• Vaccarino, F. J., Bloom, F. E., Koob, G. F. Blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat Psychopharmacology  1985 86:37-42  DOI:10.1007/bf00431681  PMID:2991967
• Bakhit, C., Bloom, F. E., Malfroy, B., Sutcliffe, J. G. Brain-specific polypeptide 1B236 exists in multiple molecular forms Proceedings of the National Academy of Sciences of the United States of America  1985 82:2009-2013  DOI:10.1073/pnas.82.7.2009  PMID:3856879
• Chavkin, C., Shoemaker, W. J., McGinty, J. F., Bayon, A., Bloom, F. E. Characterization of the prodynorphin and proenkephalin neuropeptide systems in rat hippocampus Journal of Neuroscience  1985 5:808-816  PMID:3838345
• Koob, G. F., Bloom, F. E. Corticotropin-releasing factor and behavior Federation Proceedings  1985 44:259-263  PMID:3871412
• Vaccarino, F. J., Pettit, H. O., Bloom, F. E., Koob, G. F. Effects of intracerebroventricular administration of methyl naloxonium chloride on heroin self-administration in the rat Pharmacology, Biochemistry and Behavior  1985 23:495-498  DOI:10.1016/0091-3057(85)90027-9
• Battenberg, E. L. F., Bloom, F. E., Sutcliffe, J. G. Immunocytochemical mapping of 1B236, a brain-specific neuronal polypeptide deduced from the sequence of a cloned mRNA Journal of Neuroscience  1985 5:1781-1802  PMID:4020419
• Bloom, F. E. Neuropeptides and other mediators in the central nervous-system Journal of Immunology  1985 135:S743-S745
• Bloom, F. E. Neurotransmitter diversity and its functional-significance Journal of the Royal Society of Medicine  1985 78:189-192  PMID:2857791  PMCID:PMC1289631
• Koob, G. F., Dantzer, R., Rodriguez, F., Bloom, F. E., Lemoal, M. Osmotic-stress mimics effects of vasopressin on learned behavior Nature  1985 315:750-752  DOI:10.1038/315750a0  PMID:4010780
• Chavkin, C., Henriksen, S. J., Siggins, G. R., Bloom, F. E. Selective inactivation of opioid receptors in rat hippocampus demonstrates that dynorphin-a and dynorphin-b may act on mu-receptors in the ca1 region Brain Research  1985 331:366-370  DOI:10.1016/0006-8993(85)91565-3  PMID:2859095
• Morrison, J. H., Rogers, J., Scherr, S., Benoit, R., Bloom, F. E. Somatostatin immunoreactivity in neuritic plaques of alzheimers patients Nature  1985 314:90-92  DOI:10.1038/314090a0  PMID:2858056
• Benoit, R., Bohlen, P., Ling, N., Esch, F., Baird, A., Ying, S. Y., Wehrenberg, W. B., Guillemin, R., Morrison, J. H., Bakhit, C., Koda, L., Bloom, F. E. Somatostatin-28 1-12 - like peptides Advances in Experimental Medicine and Biology  1985 188:89-107  PMID:2863951
• Vaccarino, F. J., Bloom, F. E., Rivier, J., Vale, W., Koob, G. F. Stimulation of food-intake in rats by centrally administered hypothalamic growth hormone-releasing factor Nature  1985 314:167-168  DOI:10.1038/314167a0  PMID:3919314
• Ferron, A., Siggins, G. R., Bloom, F. E. Vasoactive intestinal polypeptide acts synergistically with norepinephrine to depress spontaneous discharge rate in cerebral cortical-neurons Proceedings of the National Academy of Sciences of the United States of America  1985 82:8810-8812  DOI:10.1073/pnas.82.24.8810  PMID:3866254
• Lebrun, C., Lemoal, M., Koob, G. F., Bloom, F. E. Vasopressin pressor antagonist injected centrally reverses behavioral-effects of peripheral injection of vasopressin, but only at doses that reverse increase in blood-pressure Regulatory Peptides  1985 11:173-181  DOI:10.1016/0167-0115(85)90077-1  PMID:4035008
• Way, W. L., Hosobuchi, Y., Johnson, B. H., Eger, E. I., Bloom, F. E. Anesthesia does not increase opioid peptides in cerebrospinal fluid of humans Anesthesiology  1984 60:43-45  DOI:10.1097/00000542-198401000-00009  PMID:6318607
• Lebrun, C. J., Rigter, H., Martinez, J. L., Koob, G. F., Lemoal, M., Bloom, F. E. Antagonism of effects of vasopressin (avp) on inhibitory avoidance by a vasopressin antagonist peptide dptyr(me)avp Life Sciences  1984 35:1505-1512  DOI:10.1016/0024-3205(84)90168-1  PMID:6482669
• Lemoal, M., Dantzer, R., Mormede, P., Baduel, A., Lebrun, C., Ettenberg, A., Vanderkooy, D., Wenger, J., Deyo, S., Koob, G. F., Bloom, F. E. Behavioral-effects of peripheral administration of arginine vasopressin - a review of our search for a mode of action and a hypothesis Psychoneuroendocrinology  1984 9:319-341  DOI:10.1016/0306-4530(84)90042-8  PMID:6514931
• Bloom, F. E., Lai, C., Lerner, R. A., Sutcliffe, J. G. Brain-specific genes have identifier sequences in their introns Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1984 81:713-717  DOI:10.1073/pnas.81.3.713  PMID:6583673
• Pettit, H. O., Ettenberg, A., Bloom, F. E., Koob, G. F. Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats Psychopharmacology  1984 84:167-173  DOI:10.1007/bf00427441  PMID:6438676
• Koob, G. F., Thatcherbritton, K., Britton, D. R., Roberts, D. C. S., Bloom, F. E. Destruction of the locus coeruleus or the dorsal ne bundle does not alter the release of punished responding by ethanol and chlordiazepoxide Physiology & Behavior  1984 33:479-485  DOI:10.1016/0031-9384(84)90172-0  PMID:6542682
• Baird, A., Bloch, B., Bloom, F. E., Bohlen, P., Gubler, U., Leguellec, D., Reymond, C. Detection of the messenger RNA coding for preproenkephalin A in bovine adrenal by in situ hybridization Regulatory Peptides  1984 8:345-354  DOI:10.1016/0167-0115(84)90045-4  PMID:6548571
• Britton, K. T., Svensson, T., Schwartz, J., Bloom, F. E., Koob, G. F. Dorsal noradrenergic bundle lesions fail to alter opiate withdrawal or suppression of opiate withdrawal by clonidine Life Sciences  1984 34:133-139  DOI:10.1016/0024-3205(84)90583-6  PMID:6537983
• Koob, G. F., Pettit, H. O., Ettenberg, A., Bloom, F. E. Effects of opiate antagonists and their quaternary derivatives on heroin self-administration in the rat Journal of Pharmacology and Experimental Therapeutics  1984 229:481-486  PMID:6716270
• Bloom, F. E. Endorphins and psychiatry - pre-clinical perspectives Psychiatric Developments  1984 2:1-21  PMID:6326090
• Bakhit, C., Koda, L., Benoit, R., Morrison, J. H., Bloom, F. E. Evidence for selective release of somatostatin-14 and somatostatin-28(1-12) from rat hypothalamus Journal of Neuroscience  1984 4:411-419  PMID:6142098
• Koda, L. Y., Madamba, S. G., Bloom, F. E. Hypotensive response of ethanol in rats pretreated with disulfiram or nitrefazole Life Sciences  1984 35:1659-1665  DOI:10.1016/0024-3205(84)90177-2  PMID:6482674
• Magistretti, P. J., Morrison, J. H., Shoemaker, W. J., Bloom, F. E. Morphological and functional correlates of vip neurons in cerebral-cortex Peptides  1984 5:213-218  DOI:10.1016/0196-9781(84)90209-2  PMID:6473153
• Bloom, F. E. Neurotransmitter molecular diversity: some views of its functional significance Biomedical Research-Tokyo  1984 5:49-56
• Rogers, J., Zornetzer, S. F., Bloom, F. E., Mervis, R. E. Senescent microstructural changes in rat cerebellum Brain Research  1984 292:23-32  DOI:10.1016/0006-8993(84)90886-2  PMID:6199084
• Morrison, J. H., Magistretti, P. J., Benoit, R., Bloom, F. E. The distribution and morphological-characteristics of the intracortical vip-positive cell - an immunohistochemical analysis Brain Research  1984 292:269-282  DOI:10.1016/0006-8993(84)90763-7  PMID:6362778
• McGinty, J. F., Vanderkooy, D., Bloom, F. E. The distribution and morphology of opioid peptide immunoreactive neurons in the cerebral-cortex of rats Journal of Neuroscience  1984 4:1104-1117  PMID:6143786
• Bloom, F. E. The functional-significance of neurotransmitter diversity American Journal of Physiology  1984 246:C184-C194  PMID:6142651
• Vanderkooy, D., Koda, L. Y., McGinty, J. F., Gerfen, C. R., Bloom, F. E. The organization of projections from the cortex, amygdala, and hypothalamus to the nucleus of the solitary tract in rat Journal of Comparative Neurology  1984 224:1-24  DOI:10.1002/cne.902240102  PMID:6715573
• McGinty, J. F., Koda, L. Y., Bloom, F. E. A combined vascular catecholamine fluorescence method reveals the relative vascularity of rat locus coeruleus and the paraventricular and supraoptic nuclei of the hypothalamus Neuroscience Letters  1983 36:117-123  DOI:10.1016/0304-3940(83)90252-5  PMID:6866325
• Gozes, I., O'Connor, D. T., Bloom, F. E. A possible high molecular-weight precursor to vasoactive intestinal polypeptide sequestered into pheochromocytoma chromaffin granules Regulatory Peptides  1983 6:111-119  DOI:10.1016/0167-0115(83)90004-6  PMID:6878752
• Schwartz, J. M., Ehlers, C. L., Detmer, W. M., Bloom, F. E. Amygdala kindling after ligation of the middle cerebral-artery in the rat Experimental Neurology  1983 80:484-490  DOI:10.1016/0014-4886(83)90300-x  PMID:6840252
• Ehlers, C. L., Russo, P. V., Mandell, A. J., Bloom, F. E. Architecture of rat nocturnal locomotion - a predictive descriptor of the effects of anti-depressant and antimanic treatments Psychopharmacology Bulletin  1983 19:692-695
• Koob, G. F., Bloom, F. E. Behavioral effects of opioid peptides British Medical Bulletin  1983 39:89-94  PMID:6340789
• Ettenberg, A., Vanderkooy, D., Lemoal, M., Koob, G. F., Bloom, F. E. Can aversive properties of (peripherally-injected) vasopressin account for its putative role in memory Behavioural Brain Research  1983 7:331-350  DOI:10.1016/0166-4328(83)90024-4  PMID:6838716
• Bloom, F. E., Sutcliffe, J. G. Cellular-localization and function of the proteins encoded by brain-specific messenger-RNAs Cold Spring Harbor Symposia on Quantitative Biology  1983 48:477-484  PMID:6586369
• Vale, W., Rivier, C., Brown, M. R., Spiess, J., Koob, G., Swanson, L., Bilezikjian, L., Bloom, F., Rivier, J. Chemical and biological characterization of corticotropin releasing-factor Recent Progress in Hormone Research  1983 39:245-270  PMID:6314446
• Bloom, F. E., Baetge, G., Deyo, S., Ettenberg, A., Koda, L., Magistretti, P. J., Shoemaker, W. J., Staunton, D. A. Chemical and physiological-aspects of the actions of lithium and anti-depressant drugs Neuropharmacology  1983 22:359-365  DOI:10.1016/0028-3908(83)90184-3
• Bloom, F. E. Chemical communication in the cns - neurotransmitters and their function Progress in Brain Research  1983 58:3-9  DOI:10.1016/s0079-6123(08)60001-1  PMID:6138811
• Ehlers, C. L., Henriksen, S. J., Wang, M., Rivier, J., Vale, W., Bloom, F. E. Corticotropin releasing-factor produces increases in brain excitability and convulsive seizures in rats Brain Research  1983 278:332-336  DOI:10.1016/0006-8993(83)90266-4  PMID:6605787
• Koda, L. Y., Bloom, F. E. Distribution of catecholamine-containing cell-bodies and blood-vessels in the rat nucleus tractus solitarius Brain Research  1983 289:71-78  DOI:10.1016/0006-8993(83)90007-0  PMID:6661657
• McGinty, J. F., Bloom, F. E. Double immunostaining reveals distinctions among opioid peptidergic neurons in the medial basal hypothalamus Brain Research  1983 278:145-153  DOI:10.1016/0006-8993(83)90233-0  PMID:6196087
• McGinty, J. F., Henriksen, S. J., Goldstein, A., Terenius, L., Bloom, F. E. Dynorphin is contained within hippocampal mossy fibers: immunochemical alterations after kainic acid administration and colchicine-induced neurotoxicity Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1983 80:589-593  DOI:10.1073/pnas.80.2.589  PMID:6132379  PMCID:PMC393425
• Magistretti, P. J., Morrison, J. H., Shoemaker, W. J., Bloom, F. E. Effect of 6-hydroxydopamine lesions on norepinephrine-induced h-3 -labeled glycogen hydrolysis in mouse cortical slices Brain Research  1983 261:159-162  DOI:10.1016/0006-8993(83)91297-0  PMID:6301624
• Bakhit, C., Benoit, R., Bloom, F. E. Effects of cysteamine on pro-somatostatin related peptides Regulatory Peptides  1983 6:169-177  DOI:10.1016/0167-0115(83)90010-1  PMID:6192467
• Chavkin, C., Bakhit, C., Bloom, F. E. Evidence for dynorphin-a as a neurotransmitter in rat hippocampus Life Sciences  1983 33:13-16  DOI:10.1016/0024-3205(83)90432-0  PMID:6141483
• Magistretti, P. J., Manthorpe, M., Bloom, F. E., Varon, S. Functional receptors for vasoactive intestinal polypeptide in cultured astroglia from neonatal rat-brain Regulatory Peptides  1983 6:71-80  DOI:10.1016/0167-0115(83)90136-2  PMID:6306734
• Bloom, F. E., Shinnick, T. M., Sutcliffe, J. G. Identifying the protein products of brain-specific genes with antibodies to chemically synthesized peptides Cell  1983 33:671-682  DOI:10.1016/0092-8674(83)90010-7  PMID:6347394
• Bloom, F. E., Battenberg, E. L. F. Immunocytochemistry of endorphins and enkephalins Methods in Enzymology  1983 103:670-687  DOI:10.1016/S0076-6879(83)03048-7  PMID:6321899
• Morrison, J. H., Benoit, R., Magistretti, P. J., Bloom, F. E. Immunohistochemical distribution of pro-somatostatin-related peptides in cerebral-cortex Brain Research  1983 262:344-351  DOI:10.1016/0006-8993(83)91031-4  PMID:6132664
• Iversen, L. L., Rossor, M. N., Reynolds, G. P., Hills, R., Roth, M., Mountjoy, C. Q., Foote, S. L., Morrison, J. H., Bloom, F. E. Loss of pigmented dopamine-beta-hydroxylase positive cells from locus coeruleus in senile dementia of alzheimer type Neuroscience Letters  1983 39:95-100  DOI:10.1016/0304-3940(83)90171-4  PMID:6633940
• Shier, W. T., Koda, L. Y., Bloom, F. E. Metabolism of h-3 dopamine following intracerebroventricular injection in rats pretreated with ethanol or chloral hydrate Neuropharmacology  1983 22:279-286  DOI:10.1016/0028-3908(83)90241-1  PMID:6843789
• Battenberg, E. L. F., Bloom, F. E., Gozes, I., Johnson, E., Katz, D. H., Liu, F. T. Monoclonal antibodies against vasoactive intestinal polypeptide: Studies of structure and related antigens Journal of Neurochemistry  1983 41:549-555  DOI:10.1111/j.1471-4159.1983.tb04774.x  PMID:6875552
• Arnsten, A. F. T., Segal, D. S., Neville, H. J., Hillyard, S. A., Janowsky, D. S., Judd, L. L., Bloom, F. E. Naloxone augments electro-physiological signs of selective attention in man Nature  1983 304:725-727  DOI:10.1038/304725a0  PMID:6888538
• Atkinson, J. H., Jr., Kremer, E. F., Risch, S. C., Bloom, F. E. Neuroendocrine function and endogenous opioid peptide systems in chronic pain Psychosomatics  1983 24:899-901, 905, 909 passim  DOI:10.1016/S0033-3182(83)73141-5  PMID:6316397
• Foote, S. L., Bloom, F. E., Astonjones, G. Nucleus locus ceruleus - new evidence of anatomical and physiological specificity Physiological Reviews  1983 63:844-914  PMID:6308694
• Atkinson, J. H., Kremer, E. F., Risch, S. C., Morgan, C. D., Azad, R. F., Ehlers, C. L., Bloom, F. E. Plasma measures of beta-endorphin beta-lipotropin-like immunoreactivity in chronic pain syndrome and psychiatric subjects Psychiatry Research  1983 9:319-327  DOI:10.1016/0165-1781(83)90005-7  PMID:6316390
• Chavkin, C., Bakhit, C., Weber, E., Bloom, F. E. Relative contents and concomitant release of prodynorphin neoendorphin-derived peptides in rat hippocampus Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1983 80:7669-7673  DOI:10.1073/pnas.80.24.7669  PMID:6143317
• Bakhit, C., Benoit, R., Bloom, F. E. Release of somatostatin-28(1-12) from rat hypothalamus in vitro Nature  1983 301:524-526  DOI:10.1038/301524a0  PMID:6130476
• Benabid, A. L., Henriksen, S. J., McGinty, J. F., Bloom, F. E. Thalamic nucleus ventro-postero-lateralis inhibits nucleus parafascicularis response to noxious stimuli through a non-opioid pathway Brain Research  1983 280:217-231  DOI:10.1016/0006-8993(83)90052-5  PMID:6652483
• Ehlers, C. L., Indik, J. H., Koob, G. F., Bloom, F. E. The effect of single and repeated electroconvulsive shock (ECS) on locomotor-activity in rats Progress in Neuro-Psychopharmacology & Biological Psychiatry  1983 7:217-222  DOI:10.1016/0278-5846(83)90110-0  PMID:6684316
• Bloom, F. E. The endorphins - a growing family of pharmacologically pertinent peptides Annual Review of Pharmacology and Toxicology  1983 23:151-170  DOI:10.1146/annurev.pa.23.040183.001055  PMID:6307119
• Ettenberg, A., Koob, G. F., Bloom, F. E. Time course of alpha-flupenthixol action explains response artifacts of neuroleptic action on brain-stimulation reward - reply Science  1983 222:1253-1254  DOI:10.1126/science.222.4629.1253-a
• Ettenberg, A., Lemoal, M., Koob, G. F., Bloom, F. E. Vasopressin potentiation in the performance of a learned appetitive task - reversal by a pressor antagonist analog of vasopressin Pharmacology, Biochemistry and Behavior  1983 18:645-647  DOI:10.1016/0091-3057(83)90294-0  PMID:6867069
• Pittman, Q. J., Rogers, J., Bloom, F. E. Arginine vasopressin deficient brattleboro rats fail to develop tolerance to the hypothermic effects of ethanol Regulatory Peptides  1982 4:33-41  DOI:10.1016/0167-0115(82)90106-9  PMID:6289383
• Koob, G. F., Bloom, F. E. Behavioral-effects of neuropeptides - endorphins and vasopressin Annual Review of Physiology  1982 44:571-582  DOI:10.1146/annurev.ph.44.030182.003035  PMID:7041806
• Schwartz, J. M., Ksir, C., Koob, G. F., Bloom, F. E. Changes in locomotor response to beta-endorphin microinfusion during and after opiate abstinence syndrome - a proposal for a model of the onset of mania Psychiatry Research  1982 7:153-161  DOI:10.1016/0165-1781(92)90088-k  PMID:6292980
• Bloom, F. E., Koda, L. Y. Chemical circuitry and central cardiovascular regulation Clinical and Experimental Hypertension  1982 4:529-541  DOI:10.3109/10641968209061597  PMID:6125281
• Bloom, F. E., Lerner, R. A., Sutcliffe, J. G. Common 82-nucleotide sequence unique to brain-RNA Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1982 79:4942-4946  DOI:10.1073/pnas.79.16.4942  PMID:6956902
• Bloom, F. E., Battenberg, E. L. F., Rivier, J., Vale, W. Corticotropin releasing-factor (crf) - immunoreactive neurons and fibers in rat hypothalamus Regulatory Peptides  1982 4:43-48  DOI:10.1016/0167-0115(82)90107-0  PMID:6750704
• Pittman, Q. J., Rogers, J., Bloom, F. E. Deficits in tolerance to ethanol in brattleboro rats Annals of the New York Academy of Sciences  1982 394:764-766  DOI:10.1111/j.1749-6632.1982.tb37496.x  PMID:6960795
• Staunton, D. A., Magistretti, P. J., Koob, G. F., Shoemaker, W. J., Bloom, F. E. Dopaminergic super-sensitivity induced by denervation and chronic receptor blockade is additive Nature  1982 299:72-74  DOI:10.1038/299072a0  PMID:7110328
• Staunton, D. A., Deyo, S. N., Shoemaker, W. J., Ettenberg, A., Bloom, F. E. Effects of chronic lithium on enkephalin systems and pain responsiveness Life Sciences  1982 31:1837-1840  DOI:10.1016/0024-3205(82)90223-5  PMID:7154836
• Staunton, D. A., Magistretti, P. J., Shoemaker, W. J., Bloom, F. E. Effects of chronic lithium treatment on dopamine-receptors in the rat corpus striatum .1. Locomotor-activity and behavioral super-sensitivity Brain Research  1982 232:391-400  DOI:10.1016/0006-8993(82)90282-7  PMID:6322914
• Staunton, D. A., Magistretti, P. J., Shoemaker, W. J., Deyo, S. N., Bloom, F. E. Effects of chronic lithium treatment on dopamine-receptors in the rat corpus striatum .2. No effect on denervation or neuroleptic-induced super-sensitivity Brain Research  1982 232:401-412  DOI:10.1016/0006-8993(82)90283-9  PMID:6322915
• Schultz, J. E., Siggins, G. R., Turck, M., Bloom, F. E. Electrophysiological and biochemical comparison of the acute and chronic effects of lithium and tricyclic antidepressants Advances in Biochemical Psychopharmacology  1982 31:347-357  PMID:6282062
• Berger, T., French, E. D., Siggins, G. R., Shier, W. T., Bloom, F. E. Ethanol and some tetrahydroisoquinolines alter the discharge of cortical and hippocampal-neurons - relationship to endogenous opioids Pharmacology, Biochemistry and Behavior  1982 17:813-821  DOI:10.1016/0091-3057(82)90365-3  PMID:7178189
• Ettenberg, A., Pettit, H. O., Bloom, F. E., Koob, G. F. Heroin and cocaine intravenous self-administration in rats - mediation by separate neural systems Psychopharmacology  1982 78:204-209  DOI:10.1007/bf00428151  PMID:6296898
• Morrison, J. H., Benoit, R., Magistretti, P. J., Ling, N., Bloom, F. E. Immunohistochemical distribution of pro-somatostatin-related peptides in hippocampus Neuroscience Letters  1982 34:137-142  DOI:10.1016/0304-3940(82)90165-3  PMID:6135179
• Henriksen, S. J., Chouvet, G., Bloom, F. E. In vivo cellular responses to electrophoretically applied dynorphin in the rat hippocampus Life Sciences  1982 31:1785-1788  DOI:10.1016/0024-3205(82)90210-7  PMID:6130440
• Morrison, J. H., Foote, S. L., Oconnor, D., Bloom, F. E. Laminar, tangential and regional organization of the noradrenergic innervation of monkey cortex: dopamine-beta-hydroxylase immunohistochemistry Brain Research Bulletin  1982 9:309-319  DOI:10.1016/0361-9230(82)90144-7  PMID:6756551
• Astonjones, G., Foote, S. L., Bloom, F. E. Low-doses of ethanol disrupt sensory responses of brain noradrenergic neurons Nature  1982 296:857-860  DOI:10.1038/296857a0  PMID:6280069
• Bloom, F. E. Neurotransmitters and cns disease - the future Lancet  1982 2:1381-1384  PMID:6129472
• Bloom, F. E. New frontiers in molecular neuroscience Trends in Neurosciences  1982 5:295-296  DOI:10.1016/0166-2236(82)90184-9
• Morrison, J. H., Foote, S. L., Molliver, M. E., Bloom, F. E., Lidov, H. G. W. Noradrenergic and serotonergic fibers innervate complementary layers in monkey primary visual-cortex - an immunohistochemical study Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1982 79:2401-2405  DOI:10.1073/pnas.79.7.2401  PMID:7048320
• McGinty, J. F., Henriksen, S. J., Goldstein, A., Terenius, L., Bloom, F. E. Opioid peptide identity and localization in hippocampus Life Sciences  1982 31:1797-1800  DOI:10.1016/0024-3205(82)90213-2  PMID:6759828
• Henriksen, S. J., Chouvet, G., McGinty, J., Bloom, F. E. Opioid-peptides in the hippocampus - anatomical and physiological considerations Annals of the New York Academy of Sciences  1982 398:207-219  DOI:10.1111/j.1749-6632.1982.tb39495.x  PMID:6130736
• Ehlers, C. L., Koob, G. F., Bloom, F. E. Post-ictal locomotor-activity in 3 different rat models of epilepsy Brain Research  1982 250:178-182  DOI:10.1016/0006-8993(82)90966-0  PMID:7139314
• Vanderkooy, D., McGinty, J. F., Koda, L. Y., Gerfen, C. R., Bloom, F. E. Visceral cortex - a direct connection from prefrontal cortex to the solitary nucleus in rat Neuroscience Letters  1982 33:123-127  DOI:10.1016/0304-3940(82)90238-5  PMID:6185887
• Bloom, F. E., Feldman, J. D., Gilman, S. C., Schwartz, J. M. β-endorphin enhances lymphocyte proliferative responses Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1982 79:4226-4230  DOI:10.1073/pnas.79.13.4226  PMID:6287475
• Astonjones, G., Bloom, F. E. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle Journal of Neuroscience  1981 1:876-886  PMID:7346592
• Roberts, D. C. S., Bloom, F. E. Adrenal steroid-induced changes in beta-adrenergic-receptor binding in rat hippocampus European Journal of Pharmacology  1981 74:37-41  DOI:10.1016/0014-2999(81)90320-4  PMID:6274649
• Koob, G. F., Lemoal, M., Gaffori, O., Manning, M., Sawyer, W. H., Rivier, J., Bloom, F. E. Arginine vasopressin and a vasopressin antagonist peptide - opposite effects on extinction of active-avoidance in rats Regulatory Peptides  1981 2:153-163  DOI:10.1016/0167-0115(81)90009-4  PMID:7255768
• Schultz, J. E., Siggins, G. R., Schocker, F. W., Turck, M., Bloom, F. E. Effects of prolonged treatment with lithium and tricyclic anti-depressants on discharge frequency, norepinephrine responses and beta-receptor binding in rat cerebellum - electro-physiological and biochemical-comparison Journal of Pharmacology and Experimental Therapeutics  1981 216:28-38  PMID:6256526
• Bloom, F. E., Siggins, G. R., Henriksen, S. J. Electrophysiologic assessment of receptor changes following chronic drug treatment Federation Proceedings  1981 40:166-172  PMID:6257556
• Ettenberg, A., Rogers, J., Koob, G. F., Bloom, F. E. Endogenous opiates and fasting Science  1981 213:1282-1282  DOI:10.1126/science.6267697  PMID:6267697
• Newlin, S. A., Mancillastrevino, J., Bloom, F. E. Ethanol causes increases in excitation and inhibition in area ca3 of the dorsal hippocampus Brain Research  1981 209:113-128  DOI:10.1016/0006-8993(81)91175-6  PMID:6260298
• Schulman, J. A., Bloom, F. E. Golgi cells of the cerebellum are inhibited by inferior olive activity Brain Research  1981 210:350-355  DOI:10.1016/0006-8993(81)90908-2  PMID:7225813
• Mancillas, J. R., McGinty, J. F., Selverston, A. I., Karten, H., Bloom, F. E. Immuno-cytochemical localization of enkephalin and substance-p in retina and eyestalk neurons of lobster Nature  1981 293:576-578  DOI:10.1038/293576a0  PMID:6169995
• Bayon, A., Shoemaker, W. J., Lugo, L., Azad, R., Ling, N., Druckercolin, R. R., Bloom, F. E. In vivo release of enkephalin from the globus pallidus Neuroscience Letters  1981 24:65-70  DOI:10.1016/0304-3940(81)90360-8  PMID:7266940
• Wiener, S. G., Shoemaker, W. J., Koda, L. Y., Bloom, F. E. Interaction of ethanol and nutrition during gestation - influence on maternal and offspring development in the rat Journal of Pharmacology and Experimental Therapeutics  1981 216:572-579  PMID:7205638
• Ehlers, C. L., Henriksen, S. J., Bloom, F. E. Levonantradol potentiates the anticonvulsant effects of diazepam and valproic acid in the kindling model of epilepsy Journal of Clinical Pharmacology  1981 21:S406-S412
• Koda, L. Y., Shoemaker, W. J., Baetge, G., Bloom, F. E. Lithium treatment decreases blood-pressure in genetically hypertensive rats European Journal of Pharmacology  1981 76:411-415  DOI:10.1016/0014-2999(81)90112-6  PMID:7327210
• Bloom, F. E. Neuropeptides Scientific American  1981 245:148-168  PMID:6117125
• Astonjones, G., Bloom, F. E. Norepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli Journal of Neuroscience  1981 1:887-900  PMID:7346593
• Ettenberg, A., Koob, G. F., Bloom, F. E. Response artifact in the measurement of neuroleptic-induced anhedonia Science  1981 213:357-359  DOI:10.1126/science.7244622  PMID:7244622
• Rogers, J., Zornetzer, S. F., Bloom, F. E. Senescent pathology of cerebellum - purkinje neurons and their parallel fiber afferents Neurobiology of Aging  1981 2:15-25  DOI:10.1016/0197-4580(81)90054-3  PMID:6267492
• Pittman, Q. J., Hatton, J. D., Bloom, F. E. Spontaneous activity in perfused hypothalamic slices - dependence on calcium content of perfusate Experimental Brain Research  1981 42:49-52  PMID:7215509
• Joyce, E. M., Koob, G. F., Strecker, R., Iversen, S. D., Bloom, F. E. The behavioral-effects of enkephalin analogs injected into the ventral tegmental area and globus pallidus Brain Research  1981 221:359-370  DOI:10.1016/0006-8993(81)90784-8  PMID:7025963
• Magistretti, P. J., Morrison, J. H., Shoemaker, W. J., Sapin, V., Bloom, F. E. Vasoactive intestinal polypeptide induces glycogenolysis in mouse cortical slices - a possible regulatory mechanism for the local-control of energy-metabolism Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1981 78:6535-6539  DOI:10.1073/pnas.78.10.6535  PMID:6118864
• Lemoal, M., Koob, G. F., Koda, L. Y., Bloom, F. E., Manning, M., Sawyer, W. H., Rivier, J. Vasopressor receptor antagonist prevents behavioral-effects of vasopressin Nature  1981 291:491-493  PMID:7231561
• Foote, S. L., Loughlin, S. E., Cohen, P. S., Bloom, F. E., Livingston, R. B. Accurate 3-dimensional reconstruction of neuronal distributions in brain - reconstruction of the rat nucleus locus coeruleus Journal of Neuroscience Methods  1980 3:159-173  DOI:10.1016/0165-0270(80)90023-0  PMID:7206782
• Siggins, G. R., Bloom, F. E. Alcohol-related electrophysiology Pharmacology, Biochemistry and Behavior  1980 13:203-211  PMID:7017760
• Jaimetcheverry, G., Shoemaker, W. J., Zieher, L. M., Bloom, F. E. Antiserum to nerve growth-factor does not prevent the increase of brain-stem noradrenaline after neonatal 6-hydroxydopa Brain Research  1980 197:547-553  DOI:10.1016/0006-8993(80)91145-2  PMID:6773617
• Karobath, M., Rogers, J., Bloom, F. E. Benzodiazepine receptors remain unchanged after chronic ethanol administration Neuropharmacology  1980 19:125-128  DOI:10.1016/0028-3908(80)90177-x  PMID:7360326
• Astonjones, G., Segal, M., Bloom, F. E. Brain aminergic axons exhibit marked variability in conduction-velocity Brain Research  1980 195:215-222  DOI:10.1016/0006-8993(80)90880-x  PMID:7397496
• Shoemaker, W. J., Koda, L. Y., Shoemaker, C. A., Bloom, F. E. Ethanol effects in chick-embryos - cerebellar purkinje neurons Neurobehavioral Toxicology  1980 2:239-242
• Foote, S. L., Astonjones, G., Bloom, F. E. Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1980 77:3033-3037  DOI:10.1073/pnas.77.5.3033  PMID:6771765
• Schlumpf, M., Shoemaker, W. J., Bloom, F. E. Innervation of embryonic rat cerebral-cortex by catecholamine-containing fibers Journal of Comparative Neurology  1980 192:361-376  DOI:10.1002/cne.901920210  PMID:7400402
• Bloom, F. E., Battenberg, E. L. F., Shibasaki, T., Benoit, R., Ling, N., Guillemin, R. Localization of gamma-melanocyte stimulating hormone (gamma-msh) immunoreactivity in rat-brain and pituitary Regulatory Peptides  1980 1:205-222  DOI:10.1016/0167-0115(80)90272-4  PMID:6262877
• Stinus, L., Koob, G. F., Ling, N., Bloom, F. E., Lemoal, M. Locomotor activation induced by infusion of endorphins into the ventral tegmental area - evidence for opiate-dopamine interactions Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1980 77:2323-2327  DOI:10.1073/pnas.77.4.2323  PMID:6929553
• Pittman, Q. J., Hatton, J. D., Bloom, F. E. Morphine and opioid-peptides reduce paraventricular neuronal-activity - studies on the rat hypothalamic slice preparation Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1980 77:5527-5531  DOI:10.1073/pnas.77.9.5527  PMID:6254087
• Iversen, L. L., Iversen, S. D., Bloom, F. E. Opiate receptors influence vasopressin release from nerve-terminals in rat neurohypophysis Nature  1980 284:350-351  DOI:10.1038/284350a0  PMID:6244503
• Rogers, J., Siggins, G. R., Schulman, J. A., Bloom, F. E. Physiological correlates of ethanol intoxication, tolerance, and dependence in rat cerebellar purkinje-cells Brain Research  1980 196:183-198  DOI:10.1016/0006-8993(80)90725-8  PMID:7190454
• Bayon, A., Koda, L., Battenberg, E., Bloom, F. E. Redistribution of endorphin and enkephalin immunoreactivity in the rat brain and pituitary after in vivo treatment with colchicine or cytochalasin B Brain Research  1980 183:103-111  DOI:10.1016/0006-8993(80)90122-5  PMID:6153550
• Bayon, A., Koda, L., Battenberg, E., Azad, R., Bloom, F. E. Regional distribution of endorphin, met5-enkephalin and leu5-enkephalin in the pigeon brain Neuroscience Letters  1980 16:75-80  DOI:10.1016/0304-3940(80)90104-4  PMID:6763159
• Rogers, J., Silver, M. A., Shoemaker, W. J., Bloom, F. E. Senescent changes in a neurobiological model system - cerebellar purkinje-cell electrophysiology and correlative anatomy Neurobiology of Aging  1980 1:3-11  DOI:10.1016/0197-4580(80)90018-4  PMID:7266732
• Rossier, J., French, E., Rivier, C., Shibasaki, T., Guillemin, R., Bloom, F. E. Stress-induced release of prolactin - blockade by dexamethasone and naloxone may indicate beta-endorphin mediation Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1980 77:666-669  DOI:10.1073/pnas.77.1.666  PMID:6244573
• Rossier, J., French, E., Gros, C., Minick, S., Guillemin, R., Bloom, F. E. Adrenalectomy, dexamethasone or stress alters opioid peptides levels in rat anterior-pituitary but not intermediate lobe or brain Life Sciences  1979 25:2105-2112  DOI:10.1016/0024-3205(79)90204-2  PMID:537470
• Moore, R. Y., Bloom, F. E. Central catecholamine neuron systems - anatomy and physiology of the norepinephrine and epinephrine systems Annual Review of Neuroscience  1979 2:113-168  DOI:10.1146/annurev.ne.02.030179.000553  PMID:231924
• Bloom, F. E. Cyclic-nucleotides in central synaptic function Federation Proceedings  1979 38:2203-2207  PMID:221275
• Lemoal, M., Koob, G. F., Bloom, F. E. Endorphins and extinction - differential actions on appetitive and adversive tasks Life Sciences  1979 24:1631-1636  DOI:10.1016/0024-3205(79)90245-5  PMID:481097
• Bloom, F. E., Ueda, T., Battenberg, E., Greengard, P. Immunocytochemical localization, in synapses, of protein-i, an endogenous substrate for protein-kinases in mammalian brain Proceedings of the National Academy of Sciences of the United States of America  1979 76:5982-5986  DOI:10.1073/pnas.76.11.5982  PMID:392512
• Siggins, G. R., Henriksen, S. J., Bloom, F. Iontophoresis of li+ antagonizes noradrenergic synaptic inhibition of rat cerebellar purkinje-cells Proceedings of the National Academy of Sciences of the United States of America  1979 76:3015-3018  DOI:10.1073/pnas.76.6.3015  PMID:288083
• Rogers, J., Wiener, S. G., Bloom, F. E. Long-term ethanol administration methods for rats - advantages of inhalation over intubation or liquid diets Behavioral and Neural Biology  1979 27:466-486  DOI:10.1016/s0163-1047(79)92061-2  PMID:575037
• Rossier, J., Rogers, J., Shibasaki, T., Guillemin, R., Bloom, F. E. Opioid peptides and alpha-melanocyte-stimulating hormone in genetically-obese (ob-ob) mice during development Proceedings of the National Academy of Sciences of the United States of America  1979 76:2077-2080  DOI:10.1073/pnas.76.4.2077  PMID:287046
• Zieglgansberger, W., French, E. D., Siggins, G. R., Bloom, F. E. Opioid peptides may excite hippocampal pyramidal neurons by inhibiting adjacent inhibitory interneurons Science  1979 205:415-417  DOI:10.1126/science.451610  PMID:451610
• Bayon, A., Shoemaker, W. J., Bloom, F. E., Mauss, A., Guillemin, R. Perinatal-development of the endorphin-containing and enkephalin-containing systems in the rat-brain Brain Research  1979 179:93-101  DOI:10.1016/0006-8993(79)90493-1  PMID:509236
• Rossier, J., Bloom, F. E., Guillemin, R. Stimulation of human periaqueductal gray for pain relief increases immunoreactive beta-endorphin in ventricular fluid Science  1979 203:279-281  PMID:83674
• Decamilli, P., Ueda, T., Bloom, F. E., Battenberg, E., Greengard, P. Widespread distribution of protein-i in the central and peripheral nervous systems Proceedings of the National Academy of Sciences of the United States of America  1979 76:5977-5981  PMID:392511  PMCID:PMC411776
• Henriksen, S. J., Bloom, F. E., McCoy, F., Ling, N., Guillemin, R. Beta-endorphin induces non-convulsive limbic seizures Proceedings of the National Academy of Sciences of the United States of America  1978 75:5221-5225  DOI:10.1073/pnas.75.10.5221  PMID:283426
• Moore, R. Y., Bloom, F. E. Central catecholamine neuron systems - anatomy and physiology of the dopamine systems Annual Review of Neuroscience  1978 1:129-169  DOI:10.1146/annurev.ne.01.030178.001021  PMID:756202
• Robinson, R. G., Bloom, F. E. Changes in posterior hypothalamic self-stimulation following experimental cerebral infarction in rat Journal of Comparative and Physiological Psychology  1978 92:969-976  DOI:10.1037/h0077541  PMID:730862
• Jacobs, B. L., Foote, S. L., Bloom, F. E. Differential projections of neurons within dorsal raphe nucleus of rat - a horseradish-peroxidase (hrp) study Brain Research  1978 147:149-153  DOI:10.1016/0006-8993(78)90779-5  PMID:77700
• Bayon, A., Rossier, J., Mauss, A., Bloom, F. E., Iversen, L. L., Ling, N., Guillemin, R. In vitro release of 5-methionine enkephalin and 5-leucine -enkephalin from rat globus pallidus Proceedings of the National Academy of Sciences of the United States of America  1978 75:3503-3506  DOI:10.1073/pnas.75.7.3503  PMID:277953
• Koda, L. Y., Wise, R. A., Bloom, F. E. Light and electron-microscopic changes in rat dentate gyrus after lesions or stimulation of ascending locus coeruleus pathway Brain Research  1978 144:363-368  DOI:10.1016/0006-8993(78)90162-2  PMID:638766
• Iversen, L. L., Iversen, S. D., Bloom, F. E., Vargo, T., Guillemin, R. Release of enkephalin from rat globus pallidus in vitro Nature  1978 271:679-681  DOI:10.1038/271679a0  PMID:24182
• Koda, L. Y., Koob, G. F., Shier, W. T., Bloom, F. E. Tetrahydropapaveroline induces small granular vesicles in brain dopamine fibers Nature  1978 276:281-283  DOI:10.1038/276281a0  PMID:714160
• Koda, L. Y., Schulman, J. A., Bloom, F. E. Ultrastructural identification of noradrenergic terminals in rat hippocampus - unilateral destruction of locus coeruleus with 6-hydroxydopamine Brain Research  1978 145:190-195  DOI:10.1016/0006-8993(78)90810-7  PMID:638778
• Schlumpf, M., Shoemaker, W. J., Bloom, F. E. Explant cultures of catecholamine-containing neurons from rat-brain - biochemical, histofluorescence, and electron-microscopic studies Proceedings of the National Academy of Sciences of the United States of America  1977 74:4471-4475  DOI:10.1073/pnas.74.10.4471  PMID:270693
• Robinson, R. G., Bloom, F. E., Battenberg, E. L. F. Fluorescent histochemical study of changes in noradrenergic neurons following experimental cerebral infarction in rat Brain Research  1977 132:259-272  DOI:10.1016/0006-8993(77)90420-6  PMID:890481
• Rossier, J., French, E. D., Rivier, C., Ling, N., Guillemin, R., Bloom, F. E. Foot-shock induced stress increases beta-endorphin levels in blood but not brain Nature  1977 270:618-620  DOI:10.1038/270618a0  PMID:201864
• Koda, L. Y., Bloom, F. E. Light and electron-microscopic study of noradrenergic terminals in rat dentate gyrus Brain Research  1977 120:327-335  DOI:10.1016/0006-8993(77)90910-6  PMID:832125
• Bloom, F. E. Neural mechanisms of benzodiazepine actions American Journal of Psychiatry  1977 134:669-672  PMID:17306
• Nicoll, R. A., Siggins, G. R., Ling, N., Bloom, F. E., Guillemin, R. Neuronal actions of endorphins and enkephalins among brain-regions - comparative microiontophoretic study Proceedings of the National Academy of Sciences of the United States of America  1977 74:2584-2588  DOI:10.1073/pnas.74.6.2584  PMID:267951
• Hall, R. D., Bloom, F. E., Olds, J. Neuronal and neurochemical substrates of reinforcement Neurosciences Research Program Bulletin  1977 15:139-314
• Bloom, F. E. Peptide transmitters - clues to chemical cryptogram of interneuronal communication Biosystems  1977 8:179-183  DOI:10.1016/0303-2647(77)90036-3  PMID:18227
• Robinson, R. G., Bloom, F. E. Pharmacological treatment following experimental cerebral infarction - implications for understanding psychological symptoms of human stroke Biological Psychiatry  1977 12:669-680  PMID:588647
• Rossier, J., Vargo, T. M., Minick, S., Ling, N., Bloom, F. E., Guillemin, R. Regional dissociation of beta-endorphin and enkephalin contents in rat-brain and pituitary Proceedings of the National Academy of Sciences of the United States of America  1977 74:5162-5165  DOI:10.1073/pnas.74.11.5162  PMID:270754
• Segal, M., Bloom, F. E. Action of norepinephrine in rat hippocampus .3. Hippocampal cellular responses to locus coeruleus stimulation in awake rat Brain Research  1976 107:499-511  DOI:10.1016/0006-8993(76)90140-2  PMID:178410
• Segal, M., Bloom, F. E. Action of norepinephrine in rat hippocampus .4. Effects of locus coeruleus stimulation on evoked hippocampal unit-activity Brain Research  1976 107:513-525  DOI:10.1016/0006-8993(76)90141-4  PMID:178411
• Nathanson, J. A., Bloom, F. E. Heavy-metals and adenosine cyclic 3',5'-monophosphate metabolism - possible relevance to heavy-metal toxicity Molecular Pharmacology  1976 12:390-398  PMID:180396
• Bloom, F. E. Possible sites in neuron for interactions of drugs of abuse Annals of the New York Academy of Sciences  1976 281:11-23  DOI:10.1111/j.1749-6632.1976.tb27916.x  PMID:1071363
• Bloom, F. E., Battenberg, E. L. F. Rapid, simple and sensitive method for demonstration of central catecholamine-containing neurons and axons by glyoxylic acid-induced fluorescence .2. Detailed description of methodology Journal of Histochemistry & Cytochemistry  1976 24:561-571  PMID:1270793
• Landis, S. C., Shoemaker, W. J., Schlumpf, M., Bloom, F. E. Catecholamines in mutant mouse cerebellum - fluorescence microscopic and chemical studies Brain Research  1975 93:253-266  DOI:10.1016/0006-8993(75)90349-2  PMID:1174970
• Shoemaker, W. J., Balentine, L. T., Siggins, G. R., Hoffer, B. J., Henriksen, S. J., Bloom, F. E. Characteristics of release of adenosine 3'-5' - monophosphate from micropipets by microiontophoresis Journal of Cyclic Nucleotide Research  1975 1:97-106  PMID:4474
• Robinson, R. G., McHugh, P. R., Bloom, F. E. Chlorpromazine induced hyperphagia in rat Psychopharmacology Communications  1975 1:37-50  PMID:1223991
• Stone, T. W., Taylor, D. A., Bloom, F. E. Cyclic-amp and cyclic-gmp may mediate opposite neuronal responses in rat cerebral-cortex Science  1975 187:845-847  DOI:10.1126/science.163488  PMID:163488
• Robinson, R. G., Shoemaker, W. J., Schlumpf, M., Valk, T., Bloom, F. E. Effect of experimental cerebral infarction in rat-brain on catecholamines and behavior Nature  1975 255:332-334  DOI:10.1038/255332a0  PMID:1128692
• Freedman, R., Foote, S. L., Bloom, F. E. Histochemical characterization of a neocortical projection of nucleus locus coeruleus in squirrel-monkey Journal of Comparative Neurology  1975 164:209-231  DOI:10.1002/cne.901640205  PMID:810499
• Goodman, D. B. P., Bloom, F. E., Battenberg, E. R., Rasmussen, H., Davis, W. L. Immunofluorescent localization of cyclic-amp in toad urinary-bladder - possible intercellular transfer Science  1975 188:1023-1025  DOI:10.1126/science.167437  PMID:167437
• Nathanson, J. A., Bloom, F. E. Lead-induced inhibition of brain adenyl-cyclase Nature  1975 255:419-420  DOI:10.1038/255419a0  PMID:165434
• Bloom, F. E. Modern concepts in electrophysiology for psychiatry Psychopharmacology Communications  1975 1:579-585  PMID:817377
• Bloom, F. E. Monoaminergic neurotoxins - are they selective Journal of Neural Transmission  1975 37:183-187  DOI:10.1007/bf01670127  PMID:1185164
• Kebabian, J. W., Bloom, F. E., Steiner, A. L., Greengard, P. Neurotransmitters increase cyclic nucleotides in postganglionic neurons - immunocytochemical demonstration Science  1975 190:157-159  DOI:10.1126/science.241121  PMID:241121
• Lauder, J. M., Bloom, F. E. Ontogeny of monoamine neurons in locus coeruleus, raphe nuclei and substantia nigra of rat .2. Synaptogenesis Journal of Comparative Neurology  1975 163:251-264  DOI:10.1002/cne.901630302  PMID:240873
• Battenberg, E. L. F., Bloom, F. E. Rapid, simple and more sensitive method for demonstration of central catecholamine-containing neurons and axons by glyoxylic-acid induced fluorescence .1. Specificity Psychopharmacology Communications  1975 1:3-13  PMID:1223990
• Bloom, F. E. Role of cyclic nucleotides in central synaptic function Reviews of Physiology Biochemistry and Pharmacology  1975 74:1-103  PMID:1841
• Landis, S. C., Bloom, F. E. Ultrastructural identification of noradrenergic boutons in mutant and normal mouse cerebellar cortex Brain Research  1975 96:299-305  DOI:10.1016/0006-8993(75)90738-6  PMID:1175014
• Segal, M., Bloom, F. E. Action of norepinephrine in rat hippocampus .1. Iontophoretic studies Brain Research  1974 72:79-97  DOI:10.1016/0006-8993(74)90652-0  PMID:4364476
• Segal, M., Bloom, F. E. Action of norepinephrine in rat hippocampus .2. Activation of input pathway Brain Research  1974 72:99-114  DOI:10.1016/0006-8993(74)90653-2  PMID:4364477
• Chu, N. S., Bloom, F. E. Activity patterns of catecholamine-containing pontine neurons in dorsolateral tegmentum of unrestrained cats Journal of Neurobiology  1974 5:527-544  DOI:10.1002/neu.480050605  PMID:4373534
• Pickel, V. M., Segal, M., Bloom, F. E. Autoradiographic study of efferent pathways of nucleus locus coeruleus Journal of Comparative Neurology  1974 155:15-41  DOI:10.1002/cne.901550103  PMID:4836061
• Pickel, V. M., Segal, M., Bloom, F. E. Axonal proliferation following lesions of cerebellar peduncles - combined fluorescence microscopic and autoradiographic study Journal of Comparative Neurology  1974 155:43-59  DOI:10.1002/cne.901550104  PMID:4836062
• Chu, N. S., Bloom, F. E. Catecholamine-containing neurons in cat dorsolateral pontine tegmentum: distribution of cell bodies and some axonal projections Brain Research  1974 66:1-21  DOI:10.1016/0006-8993(74)90075-4
• Sheu, Y. S., Nelson, J. P., Bloom, F. E. Discharge patterns of cat raphe neurons during sleep and waking Brain Research  1974 73:263-276  DOI:10.1016/0006-8993(74)91048-8  PMID:4364625
• Bloom, F. E., Siggins, G. R., Hoffer, B. J. Interpreting failures to confirm depression of cerebellar purkinje-cells by cyclic-amp Science  1974 185:627-629  DOI:10.1126/science.185.4151.627  PMID:4366788
• Kauffman, F. C., Pickel, V. M., Sims, K. L., Bloom, F. E. Localization of nicotinamide adenine-dinucleotide phosphate-dependent dehydrogenases in catecholamine-containing neurons of rat-brain - studies on nucleus locus ceruleus Journal of Histochemistry & Cytochemistry  1974 22:20-28  PMID:4133068
• Lauder, J. M., Bloom, F. E. Ontogeny of monoamine neurons in locus coeruleus, raphe nuclei and substantia nigra of rat .1. Cell-differentiation Journal of Comparative Neurology  1974 155:469-481  DOI:10.1002/cne.901550407  PMID:4847734
• Bloom, F. E. To spritz or not to spritz - doubtful value of aimless iontophoresis Life Sciences  1974 14:1819-1834  DOI:10.1016/0024-3205(74)90400-7  PMID:4368008
• Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Activation of pathway from locus coeruleus to rat cerebellar purkinje neurons - pharmacological evidence of noradrenergic central inhibition Journal of Pharmacology and Experimental Therapeutics  1973 184:553-569  PMID:4347049
• Sims, K. L., Davis, G. A., Bloom, F. E. Activities of 3,4-dihydroxy-l-phenylalanine and 5-hydroxy-l-tryptophan decarboxylases in rat-brain - assay characteristics and distribution Journal of Neurochemistry  1973 20:449-464  DOI:10.1111/j.1471-4159.1973.tb12144.x  PMID:4540567
• Nelson, C. N., Hoffer, B. J., Chu, N. S., Bloom, F. E. Cytochemical and pharmacological studies on polysensory neurons in primate frontal cortex Brain Research  1973 62:115-133  DOI:10.1016/0006-8993(73)90623-9  PMID:4148775
• Hanker, J. S., Kusyk, C. J., Bloom, F. E., Pearse, A. G. E. Demonstration of dehydrogenases and monoamine-oxidase by formation of osmium blacks at sites of hatchetts brown Histochemie  1973 33:205-230  PMID:4119081
• Bloom, F. E. Dynamic synaptic communication - finding vocabulary Brain Research  1973 62:299-305  DOI:10.1016/0006-8993(73)90690-2  PMID:4148549
• Davis, G. A., Bloom, F. E. Isolation of synaptic junctional complexes from rat-brain Brain Research  1973 62:135-153  DOI:10.1016/0006-8993(73)90624-0  PMID:4128804
• Siggins, G. R., Battenberg, E. F., Hoffer, B. J., Bloom, F. E., Steiner, A. L. Noradrenergic stimulation of cyclic adenosine monophosphate in rat purkinje neurons: An immunocytochemical study Science  1973 179:585-588  DOI:10.1126/science.179.4073.585  PMID:4346826
• Chu, N., Bloom, F. E. Norepinephrine-containing neurons - changes in spontaneous discharge patterns during sleeping and waking Science  1973 179:908-910  DOI:10.1126/science.179.4076.908  PMID:4347167
• Pickel, V. M., Krebs, H., Bloom, F. E. Proliferation of norepinephrine-containing axons in rat cerebellar cortex after peduncle lesions Brain Research  1973 59:169-179  DOI:10.1016/0006-8993(73)90258-8  PMID:4747749
• Sims, K. L., Bloom, F. E. Rat-brain l-3,4-dihydroxyphenylalanine and l-5-hydroxy-tryptophan decarboxylase activities - differential effect of 6-hydroxydopamine Brain Research  1973 49:165-175  DOI:10.1016/0006-8993(73)90408-3  PMID:4540548
• Davis, G. A., Bloom, F. E. Subcellular particles separated through a histochemical reaction Analytical Biochemistry  1973 51:429-435  DOI:10.1016/0003-2697(73)90496-x  PMID:4700192
• Bloom, F. E. Ultrastructural identification of catecholamine-containing central synaptic terminals Journal of Histochemistry & Cytochemistry  1973 21:333-348  PMID:4122462
• Bloom, F. E., Wedner, H. J., Parker, C. W. Use of antibodies to study cell structure and metabolism Pharmacological Reviews  1973 25:343-358  PMID:4361228
• Bloom, F. E., Hoffer, B. J., Battenberg, E. R., Siggins, G. R., Steiner, A. L., Parker, C. W., Wedner, H. J. Adenosine 3',5'-monophosphate is localized in cerebellar neurons: Immunofluorescence evidence Science  1972 177:436-438  DOI:10.1126/science.177.4047.436  PMID:4339615
• Silberstein, S. D., Johnson, D. G., Bloom, F. E., Kopin, I. J., Hanbauer, I. Axonal sprouts and [3h]norepinephrine uptake by superior cervical ganglia in organ culture Proceedings of the National Academy of Sciences of the United States of America  1972 69:1450-1455  DOI:10.1073/pnas.69.6.1450  PMID:4504357  PMCID:PMC426723
• Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Cyclic AMP-mediated adrenergic synapses to cerebellar Purkinje cells Advances in Cyclic Nucleotide Research  1972 1:411-423  PMID:4353180
• Bloom, F. E., Barker, J. L., Hoffer, B. J., Siggins, G. R., Nicoll, R. A. Effects of serotonin on central neurons: Microiontophoretic administration Federation Proceedings  1972 31:97-106  PMID:4333253
• Sims, K. L., Weitsen, H. A., Bloom, F. E. Gaba catabolism: Localization of succinic semialdehyde dehydrogenase in brain motor and sensory nuclei Science  1972 175:1479-1480  DOI:10.1126/science.175.4029.1479  PMID:5013679
• Aghajanian, G. K., Bloom, F. E., Haigler, H. J. Lysergic-acid diethylamide and serotonin - direct action on serotonin-containing neurons in rat-brain Life Science Part 1 Physiology & Pharmacology  1972 11:615-622  DOI:10.1016/0024-3205(72)90153-1
• Bloom, F. E., Hoffer, B. J., Siggins, G. R. Norepinephrine mediated cerebellar synapses: A model system for neuropsychopharmacology Biological Psychiatry  1972 4:157-177  PMID:4337435
• Hanker, J. S., Anderson, W. A., Bloom, F. E. Osmiophilic polymer generation: Catalysis by transition metal compounds in ultrastructural cytochemistry Science  1972 175:991-993  DOI:10.1126/science.175.4025.991  PMID:5009401
• Iversen, L. L., Bloom, F. E. Studies of the uptake of 3 h-gaba and ( 3 h)glycine in slices and homogenates of rat brain and spinal cord by electron microscopic autoradiography Brain Research  1972 41:131-143  DOI:10.1016/0006-8993(72)90621-x  PMID:5036031
• Siggins, G. R., Hoffer, B. J., Oliver, A. P., Bloom, F. E. Activation of a central noradrenergic projection to cerebellum Nature  1971 233:481-483  DOI:10.1038/233481a0  PMID:4939543
• Godfraind, J. M., Pumain, R., Siggins, G. R., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate and norepinephrine: Effect on purkinje cells in rat cerebellar cortex Science  1971 174:1257-1259  PMID:4332286
• Siggins, G. R., Oliver, A. P., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate and norepinephrine: Effects on transmembrane properties of cerebellar purkinje cells Science  1971 171:192-194  DOI:10.1126/science.171.3967.192  PMID:4322158
• Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Cyclic amp mediation of norepinephrine inhibition in rat cerebellar cortex: A unique class of synaptic responses Annals of the New York Academy of Sciences  1971 185:531-549  PMID:4330518
• Sims, K. L., Weitsen, H. A., Bloom, F. E. Histochemical localization of brain succinic semialdehyde dehydrogenase-a gamma-aminobutyric acid degradative enzyme Journal of Histochemistry & Cytochemistry  1971 19:405-415  DOI:10.1177/19.7.405  PMID:4105040
• Bloom, F. E., Iversen, L. L. Localizing h-3-gaba in nerve terminals of rat cerebral cortex by electron microscopic autoradiography Nature  1971 229:628-630  DOI:10.1038/229628a0  PMID:4925465
• Siggins, G., Hoffer, B., Bloom, F. Prostaglandin-norepinephrine interactions in brain: Microelectrophoretic and histochemical correlates Annals of the New York Academy of Sciences  1971 180:302-323  DOI:10.1111/j.1749-6632.1971.tb53199.x  PMID:5286100
• Hoffer, B. J., Siggins, G. R., Woodward, D. J., Bloom, F. E. Spontaneous discharge of purkinje neurons after destruction of catecholamine-containing afferents by 6-hydroxydopamine Brain Research  1971 30:425-430  DOI:10.1016/0006-8993(71)90095-3  PMID:4329214
• Bloom, F. E., Hoffer, B. J., Siggins, G. R. Studies on norepinephrine-containing afferents to purkinje cells of art cerebellum. I. Localization of the fibers and their synapses Brain Research  1971 25:501-521  DOI:10.1016/0006-8993(71)90457-4  PMID:5544323
• Siggins, G. R., Hoffer, B. J., Bloom, F. E. Studies on norepinephrine-containing afferents to purkinje cells of rat cerebellum. 3. Evidence for mediation of norepinephrine effects by cyclic 3',5'-adenosine monophosphate Brain Research  1971 25:535-553  DOI:10.1016/0006-8993(71)90459-8  PMID:4322679
• Hoffer, B. J., Siggins, G. R., Bloom, F. E. Studies on norepinephrine-containing afferents to purkinje cells of rat cerebellum. Ii. Sensitivity of purkinje cells to norepinephrine and related substances administered by microiontophoresis Brain Research  1971 25:523-534  DOI:10.1016/0006-8993(71)90458-6  PMID:4395919
• Woodward, D. J., Hoffer, B. J., Siggins, G. R., Bloom, F. E. The ontogenetic development of synaptic junctions, synaptic activation and responsiveness to neurotransmitter substances in rat cerebellar purkinje cells Brain Research  1971 34:73-97  DOI:10.1016/0006-8993(71)90352-0  PMID:4330971
• Shorr, S. S., Bloom, F. E. Acino-insular cells in normal rat pancreas Yale Journal of Biology and Medicine  1970 43:47-49  PMID:4918984  PMCID:PMC2591532
• Siggins, G. R., Bloom, F. E. Cytochemical and physiological effects of 6-hydroxydopamine on periarteriolar nerves of frogs Circulation Research  1970 27:23-38  PMID:5424564
• Shorr, S. S., Bloom, F. E. Fine structure of islet-cell innervation in the pancreas of normal and alloxan-treated rats Zeitschrift für Zellforschung und Mikroskopische Anatomie  1970 103:12-25  DOI:10.1007/bf00335397  PMID:4904355
• Stjarne, L., Roth, R. H., Bloom, F. E., Giarman, N. J. Norepinephrine concentrating mechanisms in sympathetic nerve trunks Journal of Pharmacology and Experimental Therapeutics  1970 171:70-79  PMID:5410939
• Bloom, F. E., Giarman, N. J. The effects of p-Cl-phenylalanine on the content and cellular distribution of 5-HT in the rat pineal gland: combined biochemical and electron microscopic analyses Biochemical Pharmacology  1970 19:1213-1219  DOI:10.1016/0006-2952(70)90381-3
• Boadle, M. C., Bloom, F. E. A method for the fine structural localization of monoamine oxidase Journal of Histochemistry & Cytochemistry  1969 17:331-340  PMID:4896953
• Siggins, G. R., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate: Possible mediator for norepinephrine effects on cerebellar purkinje cells Science  1969 165:1018-1020  DOI:10.1126/science.165.3897.1018  PMID:4308638
• Aghajanian, G. K., Bloom, F. E., Sheard, M. H. Electron microscopy of degeneration within the serotonin pathway of rat brain Brain Research  1969 13:266-273  DOI:10.1016/0006-8993(69)90286-8  PMID:5772424
• Bloom, F. E., Algeri, S., Groppetti, A., Revuelta, A., Costa, E. Lesions of central norepinephrine terminals with 6-oh-dopamine: Biochemistry and fine structure Science  1969 166:1284-1286  DOI:10.1126/science.166.3910.1284  PMID:5350323
• Hoffer, B. J., Siggins, G. R., Bloom, F. E. Prostaglandins e1 and e2 antagonize norepinephrine effects on cerebellar purkinje cells: Microelectrophoretic study Science  1969 166:1418-1420  DOI:10.1126/science.166.3911.1418  PMID:5350346
• Hughes, J., Gillis, C. N., Bloom, F. E. The uptake and disposition of dl-norepinephrine in perfused rat lung Journal of Pharmacology and Experimental Therapeutics  1969 169:237-248  PMID:5824606
• Bloom, F. E., Aghajanian, G. K. An electron microscopic analysis of large granular synaptic vesicles of the brain in relation to monoamine content Journal of Pharmacology and Experimental Therapeutics  1968 159:261-273  PMID:5638647
• Bloom, F. E., Aghajanian, G. K. An osmiophilic substance in brain synaptic vesicles not associated with catecholamine content Experientia  1968 24:1225-1227  DOI:10.1007/bf02146636  PMID:5703021
• Bloom, F. E., Aghajanian, G. K. Fine structural and cytochemical analysis of the staining of synaptic junctions with phosphotungstic acid Journal of Ultrastructure Research  1968 22:361-375  DOI:10.1016/s0022-5320(68)90027-0  PMID:4173151
• Roth, R. H., Stjarne, L., Bloom, F. E., Giarman, N. J. Light and heavy norepinephrine storage particles in the rat heart and in bovine splenic nerve Journal of Pharmacology and Experimental Therapeutics  1968 162:203-212  PMID:5666978
• Bloom, F. E., Giarman, N. J. Physiologic and pharmacologic considerations of biogenic amines in the nervous system Annual Review of Pharmacology  1968 8:229-258  DOI:10.1146/annurev.pa.08.040168.001305  PMID:5302125
• Aghajanian, G. K., Bloom, F. E. Electron-microscopic localization of tritiated norepinephrine in rat brain: Effect of drugs Journal of Pharmacology and Experimental Therapeutics  1967 156:407-416  PMID:6027453
• Aghajanian, G. K., Bloom, F. E. Localization of tritiated serotonin in rat brain by electron-microscopic autoradiography Journal of Pharmacology and Experimental Therapeutics  1967 156:23-30  PMID:6023598
• Morris, N. R., Aghajanian, G. K., Bloom, F. E. Magnesium pemoline: Failure to affect in vivo synthesis of brain rna Science  1967 155:1125-1126  DOI:10.1126/science.155.3766.1125  PMID:4381484
• Bloom, F. E., Barrnett, R. J. The fine structural localization of cholinesterases in nervous tissue Annals of the New York Academy of Sciences  1967 144:626-645  DOI:10.1111/j.1749-6632.1967.tb53799.x
• Bloom, F. E., Aghajanian, G. K. Cytochemistry of synapses: Selective staining for electron microscopy Science  1966 154:1575-1577  DOI:10.1126/science.154.3756.1575  PMID:5924927
• Aghajanian, G. K., Bloom, F. E. Electron-microscopic autoradiography of rat hypothalamus after intraventricular h3-norepinephrine Science  1966 153:308-310  DOI:10.1126/science.153.3733.308  PMID:17780004
• Bloom, F. E., Barrnett, R. J. Fine structural localization of acetylcholinesterase in electroplaque of the electric eel Journal of Cell Biology  1966 29:475-495  DOI:10.1083/jcb.29.3.475  PMID:5962939  PMCID:PMC2106980
• Bloom, F. E., Barrnett, R. J. Fine structural localization of noradrenaline in vesicles of autonomic nerve endings Nature  1966 210:599-601  DOI:10.1038/210599a0  PMID:6007247
• Van Orden, L. S. 3rd, Bloom, F. E., Barrnett, R. J., Giarman, N. J. Histochemical and functional relationships of catecholamines in adrenergic nerve endings. I. Participation of granular vesicles Journal of Pharmacology and Experimental Therapeutics  1966 154:185-199  PMID:5950955
• Aghajanian, G. K., Bloom, F. E., Lovell, R. A., Sheard, M. H., Freedman, D. X. The uptake of 5-hydroxytryptamine-(3)H from the cerebral ventricles: autoradiographic localization Biochemical Pharmacology  1966 15:1401-1403  DOI:10.1016/0006-2952(66)90051-7
• Bloom, F. E., Costa, E., Salmoiraghi, G. C. Anesthesia and the responsiveness of individual neurons of the caudate nucleus of the cat to acetylcholine, norepinephrine and dopamine administered by microelectrophoresis Journal of Pharmacology and Experimental Therapeutics  1965 150:244-252  PMID:5855881
• Salmoiraghi, G. C., Costa, E., Bloom, F. E. Pharmacology of central synapses Annual Review of Pharmacology  1965 5:213-234  DOI:10.1146/annurev.pa.05.040165.001241  PMID:14287881
• Salmoiraghi, G. C., Bloom, F. E., Costa, E. Adrenergic mechanisms in rabbit olfactory bulb American Journal of Physiology  1964 207:1417-1424  PMID:14251955
• Bloom, F. E., Costa, E., Salmoiraghi, G. C. Analysis of individual rabbit olfactory bulb neuron responses to the microelectrophoresis of acetylcholine, norepinephrine and serotonin synergists and antagonists Journal of Pharmacology and Experimental Therapeutics  1964 146:16-23  PMID:14221220
• Bloom, F. E., Baumgarten, R. V., Oliver, A. P., Costa, E., Salmoiraghi, G. C. Microelectrophoretic studies of adrenergic mechanisms of rabbit olfactory neurons Life Sciences  1964 3:131-136  DOI:10.1016/0024-3205(64)90192-4  PMID:14148134
• Salmoiraghi, G. C., Bloom, F. E. Pharmacology of individual neurons: Microelectrophoresis provides closer observation of interactions between nerve cells and drugs Science  1964 144:493-499  DOI:10.1126/science.144.3618.493  PMID:14197558
• Bloom, F. E., Schoepfle, G. M. Kinetics of procaine-acetylcholine antagonism American Journal of Physiology  1963 204:73-76  PMID:13971781
• Baumgarten, R. V., Salmoiraghi, G. C., Bloom, F. E., Oliver, A. P. Response of individual olfactory nerve cells to microelectrophoretically administered chemical substances Pflugers Archiv-European Journal of Physiology  1963 277:125-140  DOI:10.1007/BF00363371
• Bloom, F. E., Oliver, A. P., Salmoiraghi, G. C. The responsiveness of individual hypothalamic neurons to microelectrophoretically administered endogenous amines International Journal of Neuropharmacology  1963 2:181-193  DOI:10.1016/0028-3908(63)90019-4
• Schoepfle, G. M., Bloom, F. E. Effects of cyanide and dinitrophenol on membrane properties of single nerve fibers American Journal of Physiology  1959 197:1131-1135  PMID:14443394
• Schoepfle, G. M., Bloom, F. E., Hellam, D. Kinetics of the negative after-potential in frog single nerve fibers American Journal of Physiology  1958 193:195-202  PMID:13521007