recent publications
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academic article
- Gracey, E., Burssens, A., Cambre, I., Schett, G., Lories, R., McInnes, I. B., Asahara, H., Elewaut, D. Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis Nature Reviews Rheumatology 2020 DOI:10.1038/s41584-019-0364-x PMID:32080619
- Yamashita, S., Kataoka, K., Yamamoto, H., Kato, T., Hara, S., Yamaguchi, K., Renard-Guillet, C., Katou, Y., Shirahige, K., Ochi, H., Ogino, H., Uchida, T., et al. Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken Scientific Reports 2019 9 DOI:10.1038/s41598-019-48979-4 PMID:31467356 PMCID:PMC6715657
- Mochizuki, Y., Chiba, T., Kataoka, K., Yamashita, S., Sato, T., Kato, T., Takahashi, K., Miyamoto, T., Kitazawa, M., Hatta, T., Natsume, T., Takai, S., et al. Combinatorial CRISPR/Cas9 approach to elucidate a far-upstream enhancer complex for tissue-specific Sox9 expression Developmental Cell 2018 46:794-806 DOI:10.1016/j.devcel.2018.07.024 PMID:30146478
- Inui, M., Mokuda, S., Sato, T., Tamano, M., Takada, S., Asahara, H. Dissecting the roles of miR-140 and its host gene Nature Cell Biology 2018 20:516-518 DOI:10.1038/s41556-018-0077-4 PMID:29695789
- Nakamichi, R., Kataoka, K., Asahara, H. Essential role of Mohawk for tenogenic tissue homeostasis including spinal disc and periodontal ligament Modern Rheumatology 2018 28:933-940 DOI:10.1080/14397595.2018.1466644 PMID:29667905
- Alvarez-Garcia, O., Matsuzaki, T., Olmer, M., Miyata, K., Mokuda, S., Sakai, D., Masuda, K., Asahara, H., Lotz, M. K. FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration Aging Cell 2018 17 DOI:10.1111/acel.12800 PMID:29963746 PMCID:PMC6156454
- Matsuzaki, T., Alvarez-Garcia, O., Mokuda, S., Nagira, K., Olmer, M., Gamini, R., Miyata, K., Akasaki, Y., Su, A. I., Asahara, H., Lotz, M. K. FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis Science Translational Medicine 2018 10:eaan0746 DOI:10.1126/scitranslmed.aan0746 PMID:29444976
- Yokoyama, S., Furukawa, S., Kitada, S., Mori, M., Saito, T., Kawakami, K., Belmonte, J. C. I., Kawakami, Y., Ito, Y., Sato, T., Asahara, H. Analysis of transcription factors expressed at the anterior mouse limb bud PLoS One 2017 12 DOI:10.1371/journal.pone.0175673 PMID:28467430 PMCID:PMC5415108
- Okuda, K., Kobayashi, S., Fukaya, M., Watanabe, A., Murakami, T., Hagiwara, M., Sato, T., Ueno, H., Ogonuki, N., Komano-Inoue, S., Manabe, H., Yamaguchi, M., et al. CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility Neurobiology of Disease 2017 106:158-170 DOI:10.1016/j.nbd.2017.07.002 PMID:28688852
- Nakasuji, T., Ogonuki, N., Chiba, T., Kato, T., Shiozawa, K., Yamatoya, K., Tanaka, H., Kondo, T., Miyado, K., Miyasaka, N., Kubota, T., Ogura, A., et al. Complementary critical functions of Zfy1 and Zfy2 in mouse spermatogenesis and reproduction PLoS Genetics 2017 13 DOI:10.1371/journal.pgen.1006578 PMID:28114340 PMCID:PMC5287576
- Ito, Y., Inoue, A., Seers, T., Hato, Y., Igarashi, A., Toyama, T., Taganov, K. D., Boldin, M. P., Asahara, H. Identification of targets of tumor suppressor microRNA-34a using a reporter library system Proceedings of the National Academy of Sciences of the United States of America 2017 114:3927-3932 DOI:10.1073/pnas.1620019114 PMID:28356515 PMCID:PMC5393199
- Hasei, J., Teramura, T., Takehara, T., Onodera, Y., Horii, T., Olmer, M., Hatada, I., Fukuda, K., Ozaki, T., Lotz, M. K., Asahara, H. TWIST1 induces MMP3 expression through up-regulating DNA hydroxymethylation and promotes catabolic responses in human chondrocytes Scientific Reports 2017 7 DOI:10.1038/srep42990 PMID:28220902 PMCID:PMC5318945
- Asahara, H., Inui, M., Lotz, M. K. Tendons and ligaments: connecting developmental biology to musculoskeletal disease pathogenesis Journal of Bone and Mineral Research 2017 32:1773-1782 DOI:10.1002/jbmr.3199 PMID:28621492
- Koda, N., Sato, T., Shinohara, M., Ichinose, S., Ito, Y., Nakamichi, R., Kayama, T., Kataoka, K., Suzuki, H., Moriyama, K., Asahara, H. The transcription factor mohawk homeobox regulates homeostasis of the periodontal ligament Development 2017 144:313-320 DOI:10.1242/dev.135798 PMID:27993989
- Asahara, H. Current status and strategy of microRNA research for cartilage development and osteoarthritis pathogenesis Journal of Bone Metabolism 2016 23:121-127 DOI:10.11005/jbm.2016.23.3.121 PMID:27622175 PMCID:PMC5018604
- Naito, M., Mori, M., Inagawa, M., Miyata, K., Hashimoto, N., Tanaka, S., Asahara, H. Dnmt3a regulates proliferation of muscle satellite cells via p57Kip2 PLoS Genetics 2016 12 DOI:10.1371/journal.pgen.1006167 PMID:27415617 PMCID:PMC4944932
- Otero, M., Peng, H., El Hachem, K., Culley, K. L., Wondimu, E. B., Quinn, J., Asahara, H., Tsuchimochi, K., Hashimoto, K., Goldring, M. B. ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity Connective Tissue Research 2016 58:1-12 DOI:10.1080/03008207.2016.1200566 PMID:27310669 PMCID:PMC5326708
- Suzuki, H., Ito, Y., Shinohara, M., Yamashita, S., Ichinose, S., Kishida, A., Oyaizu, T., Kayama, T., Nakamichi, R., Koda, N., Yagishita, K., Lotz, M. K., et al. Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis Proceedings of the National Academy of Sciences of the United States of America 2016 113:7840-7845 DOI:10.1073/pnas.1522054113 PMID:27370800 PMCID:PMC4948356
- Shimbo, M., Kudo, T., Hamada, M., Jeon, H., Imamura, Y., Asano, K., Okada, R., Tsunakawa, Y., Mizuno, S., Yagami, K., Ishikawa, C., Li, H., et al. Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies Experimental Animals 2016 65:175-187 PMID:26822934 PMCID:PMC4873486
- Kayama, T., Mori, M., Ito, Y., Matsushima, T., Nakamichi, R., Suzuki, H., Ichinose, S., Saito, M., Marumo, K., Asahara, H. Gtf2ird1-dependent mohawk expression regulates mechanosensing properties of the tendon Molecular and Cellular Biology 2016 36:1297-1309 DOI:10.1128/mcb.00950-15 PMID:26884464
- Nakamichi, R., Ito, Y., Inui, M., Onizuka, N., Kayama, T., Kataoka, K., Suzuki, H., Mori, M., Inagawa, M., Ichinose, S., Lotz, M. K., Sakai, D., et al. Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs Nature Communications 2016 7 DOI:10.1038/ncomms12503 PMID:27527664 PMCID:PMC4990710
- Doiguchi, M., Nakagawa, T., Imamura, Y., Yoneda, M., Higashi, M., Kubota, K., Yamashita, S., Asahara, H., Iida, M., Fujii, S., Ikura, T., Liu, Z. Y., et al. SMARCAD1 is an ATP-dependent stimulator of nucleosomal H2A acetylation via CBP, resulting in transcriptional regulation Scientific Reports 2016 6 DOI:10.1038/srep20179 PMID:26888216 PMCID:PMC4757861
- Craney, A., Gernapudi, R., Yao, Y., Wolfson, B., Zhang, Y., Craney, A., Yao, Y., Yang, P., Asahara, H., Zhou, Q. MicroRNA 140 promotes expression of long noncoding RNA NEAT1 in adipogenesis Molecular and Cellular Biology 2016 36:30-38 DOI:10.1128/mcb.00702-15 PMID:26459763
- Tateishi, R., Akiyama, N., Miyauchi, M., Yoshinaga, R., Sasanuma, H., Kudo, T., Shimbo, M., Shinohara, M., Obata, K., Inoue, J., Shirakawa, M., Shiba, D., et al. Hypergravity provokes a temporary reduction in CD4+CD8+thymocyte number and a persistent decrease in medullary thymic epithelial cell frequency in mice PLoS One 2015 10 DOI:10.1371/journal.pone.0141650 PMID:26513242 PMCID:PMC4626100
- Ogura, Y., Miyake, N., Kou, I., Iida, A., Nakajima, M., Takeda, K., Fujibayashi, S., Shiina, M., Okada, E., Toyama, Y., Iwanami, A., Ishii, K., et al. Identification of HOXD4 mutations in spinal extradural arachnoid cyst PLoS One 2015 10 DOI:10.1371/journal.pone.0142126 PMID:26545093 PMCID:PMC4636324
- Miyata, K., Miyata, T., Nakabayashi, K., Okamura, K., Naito, M., Kawai, T., Takada, S., Kato, K., Miyamoto, S., Hata, K., Asahara, H. DNA methylation analysis of human myoblasts during in vitro myogenic differentiation: de novo methylation of promoters of muscle-related genes and its involvement in transcriptional down-regulation Human Molecular Genetics 2015 24:410-423 DOI:10.1093/hmg/ddu457 PMID:25190712 PMCID:PMC4275072
- Matsubara, Y., Kato, T., Kashimada, K., Tanaka, H., Zhi, Z., Ichinose, S., Mizutani, S., Morio, T., Chiba, T., Ito, Y., Saga, Y., Takada, S., et al. TALEN-mediated gene disruption on Y chromosome reveals critical role of EIF2S3Y in mouse spermatogenesis Stem Cells and Development 2015 24:1164-1170 DOI:10.1089/scd.2014.0466 PMID:25579647 PMCID:PMC4425228
- Otabe, K., Nakahara, H., Hasegawa, A., Matsukawa, T., Ayabe, F., Onizuka, N., Inui, M., Takada, S., Ito, Y., Sekiya, I., Muneta, T., Lotz, M., et al. Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo Journal of Orthopaedic Research 2015 33:1-8 DOI:10.1002/jor.22750 PMID:25312837 PMCID:PMC4294629
- Miyata, K., Yotsumoto, F., Nam, S. O., Odawara, T., Manabe, S., Ishikawa, T., Itamochi, H., Kigawa, J., Takada, S., Asahara, H., Kuroki, M., Miyamoto, S. Contribution of transcription factor, SP1, to the promotion of HB-EGF expression in defense mechanism against the treatment of irinotecan in ovarian clear cell carcinoma Cancer Medicine 2014 3:1159-1169 DOI:10.1002/cam4.301 PMID:25060396 PMCID:PMC4302667
- Takasawa, K., Kashimada, K., Pelosi, E., Takagi, M., Morio, T., Asahara, H., Schlessinger, D., Mizutani, S., Koopman, P. FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice FASEB Journal 2014 28:2020-2028 DOI:10.1096/fj.13-246108 PMID:24451388 PMCID:PMC3986836
- Nagata, E., Kano, H., Kato, F., Yamaguchi, R., Nakashima, S., Takayama, S., Kosaki, R., Tonoki, H., Mizuno, S., Watanabe, S., Yoshiura, K. I., Kosho, T., et al. Japanese founder duplications/triplications involving BHLHA9 are associated with split-hand/foot malformation with or without long bone deficiency and Gollop-Wolfgang complex Orphanet Journal of Rare Diseases 2014 9 DOI:10.1186/s13023-014-0125-5 PMID:25351291 PMCID:PMC4205278
- Shinohara, M., Chang, B. Y., Buggy, J. J., Nagai, Y., Kodama, T., Asahara, H., Takayanagi, H. The orally available Btk inhibitor ibrutinib (PCI-32765) protects against osteoclast-mediated bone loss Bone 2014 60:8-15 DOI:10.1016/j.bone.2013.11.025 PMID:24316417
- Akasaki, Y., Hasegawa, A., Saito, M., Asahara, H., Iwamoto, Y., Lotz, M. K. Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis Osteoarthritis and Cartilage 2014 22:162-170 DOI:10.1016/j.joca.2013.11.004 PMID:24269635 PMCID:PMC3932989
- Inui, M., Miyado, M., Igarashi, M., Tamano, M., Kubo, A., Yamashita, S., Asahara, H., Fukami, M., Takada, S. Rapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system Scientific Reports 2014 4:5396 DOI:10.1038/srep05396 PMID:24953798 PMCID:PMC4066261
- Onizuka, N., Ito, Y., Inagawa, M., Nakahara, H., Takada, S., Lotz, M., Toyama, Y., Asahara, H. The Mohawk homeobox transcription factor regulates the differentiation of tendons and volar plates Journal of Orthopaedic Science 2014 19:172-180 DOI:10.1007/s00776-013-0485-z PMID:24166359 PMCID:PMC3943675
- Matsubara, Y., Chiba, T., Kashimada, K., Morio, T., Takada, S., Mizutani, S., Asahara, H. Transcription activator-like effector nuclease-mediated transduction of exogenous gene into IL2RG locus Scientific Reports 2014 4:5043 DOI:10.1038/srep05043 PMID:24853770 PMCID:PMC4031469
- Furumatsu, T., Asahara, H. Chromatin assembly and in vitro transcription analyses for evaluation of individual protein activities in multicomponent transcriptional complexes Methods in Molecular Biology 2013 977:193-202 DOI:10.1007/978-1-62703-284-1_15 PMID:23436363
- Rakoczy, J., Fernandez-Valverde, S. L., Glazov, E. A., Wainwright, E. N., Sato, T., Takada, S., Combes, A. N., Korbie, D. J., Miller, D., Grimmond, S. M., Little, M. H., Asahara, H., et al. MicroRNAs-140-5p/140-3p modulate Leydig cell numbers in the developing mouse testis Biology of Reproduction 2013 88 DOI:10.1095/biolreprod.113.107607 PMID:23616593
- Kato, T., Miyata, K., Sonobe, M., Yamashita, S., Tamano, M., Miura, K., Kanai, Y., Miyamoto, S., Sakuma, T., Yamamoto, T., Inui, M., Kikusui, T., et al. Production of Sry knockout mouse using TALEN via oocyte injection Scientific Reports 2013 3 DOI:10.1038/srep03136 PMID:24190364 PMCID:PMC3817445
- Shimizu, H., Kubo, A., Uchibe, K., Hashimoto, M., Yokoyama, S., Takada, S., Mitsuoka, K., Asahara, H. The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo PLoS One 2013 8 DOI:10.1371/journal.pone.0075754 PMID:24146773 PMCID:PMC3797748
- Yoshitaka, T., Kawai, A., Miyaki, S., Numoto, K., Kikuta, K., Ozaki, T., Lotz, M., Asahara, H. Analysis of microRNAs expressions in chondrosarcoma Journal of Orthopaedic Research 2013 31:1992-1998 DOI:10.1002/jor.22457 PMID:23940002 PMCID:PMC3835201
- Hasegawa, A., Nakahara, H., Kinoshita, M., Asahara, H., Koziol, J., Lotz, M. K. Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis Arthritis Research & Therapy 2013 15:R29 DOI:10.1186/ar4165 PMID:23406989 PMCID:PMC3672799
- Watanabe, T., Oyama, T., Asada, M., Harada, D., Ito, Y., Inagawa, M., Suzuki, Y., Sugano, S., Katsube, K., Karsenty, G., Komori, T., Kitagawa, M., et al. MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development PLoS Genetics 2013 9:e1003132 DOI:10.1371/journal.pgen.1003132 PMID:23326237 PMCID:PMC3542067
- Matsukawa, T., Sakai, T., Yonezawa, T., Hiraiwa, H., Hamada, T., Nakashima, M., Ono, Y., Ishizuka, S., Nakahara, H., Lotz, M. K., Asahara, H., Ishiguro, N. MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes Arthritis Research & Therapy 2013 15:R28 DOI:10.1186/ar4164 PMID:23406982 PMCID:PMC3672767
- Takata, A., Otsuka, M., Yoshikawa, T., Kishikawa, T., Hikiba, Y., Obi, S., Goto, T., Kang, Y. J., Maeda, S., Yoshida, H., Omata, M., Asahara, H., et al. MicroRNA-140 acts as a liver tumor suppressor by controlling NF-kappaB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression Hepatology 2013 57:162-170 DOI:10.1002/hep.26011 PMID:22898998 PMCID:PMC3521841
- Takada, S., Sato, T., Ito, Y., Yamashita, S., Kato, T., Kawasumi, M., Kanai-Azuma, M., Igarashi, A., Kato, T., Tamano, M., Asahara, H. Targeted gene deletion of miRNAs in mice by TALEN system PLoS One 2013 8:e76004 DOI:10.1371/journal.pone.0076004 PMID:24146809 PMCID:PMC3797721
- Nakahara, H., Hasegawa, A., Otabe, K., Ayabe, F., Matsukawa, T., Onizuka, N., Ito, Y., Ozaki, T., Lotz, M. K., Asahara, H. Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation Arthritis and Rheumatism 2013 65:2081-2089 DOI:10.1002/art.38020 PMID:23686683 PMCID:PMC3840305
- Gibson, G., Asahara, H. microRNAs and cartilage Journal of Orthopaedic Research 2013 31:1333-1344 DOI:10.1002/jor.22397 PMID:23754477
- Ito, Y., Kayama, T., Asahara, H. A systems approach and skeletal myogenesis Comparative and Functional Genomics 2012 759407 DOI:10.1155/2012/759407 PMID:22991503 PMCID:PMC3443578
- Fukami, M., Tsuchiya, T., Takada, S., Kanbara, A., Asahara, H., Igarashi, A., Kamiyama, Y., Nishimura, G., Ogata, T. Complex genomic rearrangement in the SOX9 5' region in a patient with Pierre Robin sequence and hypoplastic left scapula American Journal of Medical Genetics Part A 2012 158A:1529-1534 DOI:10.1002/ajmg.a.35308 PMID:22529047
- Takada, S., Asahara, H. Current strategies for microRNA research Modern Rheumatology 2012 22:645-653 DOI:10.1007/s10165-011-0583-8 PMID:22237764
- Uchibe, K., Shimizu, H., Yokoyama, S., Kuboki, T., Asahara, H. Identification of novel transcription-regulating genes expressed during murine molar development Developmental Dynamics 2012 241:1217-1226 DOI:10.1002/dvdy.23808 PMID:22639370
- Yamashita, S., Miyaki, S., Kato, Y., Yokoyama, S., Sato, T., Barrionuevo, F., Akiyama, H., Scherer, G., Takada, S., Asahara, H. L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity Journal of Biological Chemistry 2012 287:22206-22215 DOI:10.1074/jbc.M112.343194 PMID:22547066 PMCID:PMC3381182
- Miyaki, S., Asahara, H. Macro view of microrna function in osteoarthritis Nature Reviews Rheumatology 2012 8:543-552 DOI:10.1038/nrrheum.2012.128 PMID:22890245 PMCID:PMC3572197
- Chan, E. F., Harjanto, R., Asahara, H., Inoue, N., Masuda, K., Bugbee, W. D., Firestein, G. S., Hosalkar, H. S., Lotz, M. K., Sah, R. L. Structural and functional maturation of distal femoral cartilage and bone during postnatal development and growth in humans and mice Orthopedic Clinics of North America 2012 43:173-85 DOI:10.1016/j.ocl.2012.01.005 PMID:22480467 PMCID:PMC3321216
- Asahara, H. Switching gears to an arthritis gene expression network by SirT1 cleavage Arthritis and Rheumatism 2011 63:2161-2163 DOI:10.1002/art.30276 PMID:21305531
- Awazawa, M., Ueki, K., Inabe, K., Yamauchi, T., Kubota, N., Kaneko, K., Kobayashi, M., Iwane, A., Sasako, T., Okazaki, Y., Ohsugi, M., Takamoto, I., et al. Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway Cell Metabolism 2011 13:401-412 DOI:10.1016/j.cmet.2011.02.010 PMID:21459325
- Asada, M., Rauch, A., Shimizu, H., Maruyama, H., Miyaki, S., Shibamori, M., Kawasome, H., Ishiyama, H., Tuckermann, J., Asahara, H. DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Kruppel-like factor 15 gene expression Laboratory Investigation 2011 91:203-215 DOI:10.1038/labinvest.2010.170 PMID:20956975 PMCID:PMC3025047
- Mizutani, R., Nakamura, K., Yokoyama, S., Sanbe, A., Kusakawa, S., Miyamoto, Y., Torii, T., Asahara, H., Okado, H., Yamauchi, J., Tanoue, A. Developmental expression of sorting nexin 3 in the mouse central nervous system Gene Expression Patterns 2011 11:33-40 DOI:10.1016/j.gep.2010.08.007 PMID:20817026
- Yokoyama, S., Asahara, H. The myogenic transcriptional network Cellular and Molecular Life Sciences 2011 68:1843-1849 DOI:10.1007/s00018-011-0629-2 PMID:21318263 PMCID:PMC3092062
- Wada, S., Kato, Y., Okutsu, M., Miyaki, S., Suzuki, K., Yan, Z., Schiaffino, S., Asahara, H., Ushida, T., Akimoto, T. Translational suppression of atrophic regulators by microRNA-23a integrates resistance to skeletal muscle atrophy Journal of Biological Chemistry 2011 286:38456-38465 DOI:10.1074/jbc.M111.271270 PMID:21926429 PMCID:PMC3207415
- Higashiyama, R., Miyaki, S., Yamashita, S., Yoshitaka, T., Lindman, G., Ito, Y., Sasho, T., Takahashi, K., Lotz, M., Asahara, H. Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis Modern Rheumatology 2010 20:11-17 DOI:10.1007/s10165-009-0224-7 PMID:19784544 PMCID:PMC2818344
- Otsuki, S., Hanson, S. R., Miyaki, S., Grogan, S. P., Kinoshita, M., Asahara, H., Wong, C. H., Lotz, M. K. Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways Proceedings of the National Academy of Sciences of the United States of America 2010 107:10202-10207 DOI:10.1073/pnas.0913897107 PMID:20479257 PMCID:PMC2890424
- Furumatsu, T., Asahara, H. Histone acetylation influences the activity of Sox9-related transcriptional complex Acta Medica Okayama 2010 64:351-357 PMID:21173804
- Miyaki, S., Sato, T., Inoue, A., Otsuki, S., Ito, Y., Yokoyama, S., Kato, Y., Takemoto, F., Nakasa, T., Yamashita, S., Takada, S., Lotz, M. K., et al. MicroRNA-140 plays dual roles in both cartilage development and homeostasis Genes & Development 2010 24:1173-1185 DOI:10.1101/gad.1915510 PMID:20466812 PMCID:PMC2878654
- Nakanishi, K., Nakasa, T., Tanaka, N., Ishikawa, M., Yamada, K., Yamasaki, K., Kamei, N., Izumi, B., Adachi, N., Miyaki, S., Asahara, H., Ochi, M. Responses of microRNAs 124a and 223 following spinal cord injury in mice Spinal Cord 2010 48:192-196 DOI:10.1038/sc.2009.89 PMID:19621023
- Ito, Y., Toriuchi, N., Yoshitaka, T., Ueno-Kudoh, H., Sato, T., Yokoyama, S., Nishida, K., Akimoto, T., Takahashi, M., Miyaki, S., Asahara, H. The Mohawk homeobox gene is a critical regulator of tendon differentiation Proceedings of the National Academy of Sciences of the United States of America 2010 107:10538-10542 DOI:10.1073/pnas.1000525107 PMID:20498044 PMCID:PMC2890854
- Otsuki, S., Grogan, S. P., Miyaki, S., Kinoshita, M., Asahara, H., Lotz, M. K. Tissue neogenesis and STRO-1 expression in immature and mature articular cartilage Journal of Orthopaedic Research 2010 28:96-102 DOI:10.1002/jor.20944 PMID:19603515 PMCID:PMC2905317
- Shimizu, H., Uchibe, K., Asahara, H. Large-scale whole mount in situ hybridization of mouse embryos Methods in Molecular Biology 2009 577:167-79 DOI:10.1007/978-1-60761-232-2_13 PMID:19718516
- Kumagishi, K., Nishida, K., Yamaai, T., Momota, R., Miyaki, S., Hirohata, S., Naito, I., Asahara, H., Ninomiya, Y., Ohtsuka, A. A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) expression by chondrocytes during endochondral ossification Archives of Histology and Cytology 2009 72:175-185 DOI:10.1679/aohc.72.175 PMID:20513980
- Yokoyama, S., Ito, Y., Ueno-Kudoh, H., Shimizu, H., Uchibe, K., Albini, S., Mitsuoka, K., Miyaki, S., Kiso, M., Nagai, A., Hikata, T., Osada, T., et al. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58 Developmental Cell 2009 17:836-848 DOI:10.1016/j.devcel.2009.10.011 PMID:20059953 PMCID:PMC3110151
- Ito, T., Yadav, N., Lee, J., Furumatsu, T., Yamashita, S., Yoshida, K., Taniguchi, N., Hashimoto, M., Tsuchiya, M., Ozaki, T., Lotz, M., Bedford, M. T., et al. Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification BMC Developmental Biology 2009 9:47 DOI:10.1186/1471-213x-9-47 PMID:19725955 PMCID:PMC2754437
- Abe, Y., Oka, A., Mizuguchi, M., Igarashi, T., Ishikawa, S., Aburatani, H., Yokoyama, S., Asahara, H., Nagao, K., Yamada, M., Miyashita, T. EYA4, deleted in a case with middle interhemispheric variant of holoprosencephaly, interacts with SIX3 both physically and functionally Human Mutation 2009 30:E946-E955 DOI:10.1002/humu.21094 PMID:19606496
- Yamasaki, K., Nakasa, T., Miyaki, S., Ishikawa, M., Deie, M., Adachi, N., Yasunaga, Y., Asahara, H., Ochi, M. Expression of microRNA-146a in osteoarthritis cartilage Arthritis and Rheumatism 2009 60:1035-1041 DOI:10.1002/art.24404 PMID:19333945 PMCID:PMC2670476
- Nagata, Y., Nakasa, T., Mochizuki, Y., Ishikawa, M., Miyaki, S., Shibuya, H., Yamasaki, K., Adachi, N., Asahara, H., Ochi, M. Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded microRNA-15a Arthritis and Rheumatism 2009 60:2677-2683 DOI:10.1002/art.24762 PMID:19714650
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