Publications in VIVO
 

Hodder, Peter Faculty Member

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selected publications

Research

research overview

  • The Hodder laboratory, in collaboration with other scientists at Scripps and around the world, identifies “lead” compounds that can help better understand and ultimately cure diseases such as cancer, diabetes, Alzheimer's and hepatitis. By combining robotics , biology, chemistry and informatics, we are able to perform High-Throughput Screening , a robotic process employing sophisticated automation, detection and assay technologies that tests hundreds of thousands of drug-like compounds for biological activity both rapidly and economically. In addition we have the personnel and facilities to engage both pre- and post-HTS activities, including HTS assay development , cheminformatics , compound synthesis/procurement, compound QC (via LC-MS) and mechanism of action/profiling studies. We work with mammalian, yeast and bacterial targets. Our expertise can be accessed through collaborative mechanisms, such as the NIH’s Molecular Libraries initiative (http://mlpcn.florida.scripps.edu/ ). In other efforts, we research and develop novel automation, instrumentation and assay technologies that benefit the HTS disciplines. We are also engaged in developing novel probes and therapeutics relevant to infectious disease research.

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